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Total number of protein in "GO:0045934" GO term:  268

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 GO:0045934 Census Yes 150 0.253 63 20 0.317 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 GO:0045934 Not Cancer Driver No 74 0.124 36 6 0.167 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0045934 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0045934 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0045934 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0045934 Not Cancer Driver No 39 0.16 92 21 0.228 1
ANGEL2 ANGEL2 Q5VTE6 Protein angel homolog 2 chr1 GO:0045934 Not Cancer Driver No 56 0.103 48 6 0.125 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0045934 Not Cancer Driver No 52 0.163 83 13 0.157 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0045934 Not Cancer Driver No 62 0.263 13 1 0.077 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0045934 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0045934 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 GO:0045934 Not Cancer Driver No 23 0.064 341 21 0.062 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0045934 Census, Compendium Yes 120 0.139 619 88 0.142 4
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0045934 Not Cancer Driver No 57 0.099 571 57 0.1 7
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0045934 Census Yes 96 0.124 384 49 0.128 0
BCDIN3D BCDIN3D Q7Z5W3 RNA 5'-monophosphate methyltransferase chr12 GO:0045934 Not Cancer Driver No 27 0.092 44 2 0.045 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0045934 Census, Compendium Yes 134 0.19 328 67 0.204 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0045934 Not Cancer Driver No 21 0.044 213 10 0.047 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0045934 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0045934 Compendium Yes 141 0.136 601 70 0.116 19
BOLL_ENST00000392296 BOLL Q8N9W6 Protein boule-like chr2 GO:0045934 Not Cancer Driver No 59 0.208 78 22 0.282 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0045934 Not Cancer Driver No 14 0.05 103 6 0.058 2
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 GO:0045934 Census, Compendium Yes 83 0.127 502 70 0.139 0
CC2D1A CC2D1A Q6P1N0 Coiled-coil and C2 domain-containing protein 1A chr19 GO:0045934 Not Cancer Driver No 146 0.154 718 100 0.139 0
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0045934 Not Cancer Driver No 85 0.117 495 61 0.123 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0045934 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0045934 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0045934 Census, Compendium Yes 48 0.293 121 30 0.248 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0045934 Not Cancer Driver No 107 0.22 253 74 0.292 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0045934 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0045934 Not Cancer Driver No 58 0.122 86 16 0.186 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0045934 Not Cancer Driver No 23 0.085 230 18 0.078 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0045934 Census Yes 25 0.076 277 23 0.083 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0045934 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0045934 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0045934 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0045934 Not Cancer Driver No 164 0.14 385 48 0.125 0
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0045934 Not Cancer Driver No 24 0.153 128 19 0.148 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0045934 Not Cancer Driver No 157 0.207 641 134 0.209 0
DAZ2_ENST00000382424 DAZ2 Q13117 Deleted in azoospermia protein 2 chrY GO:0045934 Not Cancer Driver No 1 0.002 72 0 0.0 0
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 GO:0045934 Not Cancer Driver No 28 0.095 128 12 0.094 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0045934 Not Cancer Driver No 57 0.136 167 24 0.144 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0045934 Not Cancer Driver No 20 0.086 87 9 0.103 0
DEDD_ENST00000545495 DEDD O75618 Death effector domain-containing protein chr1 GO:0045934 Not Cancer Driver No 36 0.113 90 7 0.078 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0045934 Not Cancer Driver No 47 0.142 113 18 0.159 0
DHX34 DHX34 Q14147 Probable ATP-dependent RNA helicase DHX34 chr19 GO:0045934 Not Cancer Driver No 175 0.153 326 41 0.126 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0045934 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0045934 Compendium Yes 182 0.143 331 42 0.127 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0045934 Not Cancer Driver No 62 0.121 145 29 0.2 24
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0045934 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 GO:0045934 Not Cancer Driver No 67 0.108 425 48 0.113 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0045934 Not Cancer Driver No 83 0.215 10 1 0.1 0
DPPA3 DPPA3 Q6W0C5 Developmental pluripotency-associated protein 3 chr12 GO:0045934 Not Cancer Driver No 58 0.365 105 43 0.41 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0045934 Not Cancer Driver No 135 0.177 447 73 0.163 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0045934 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0045934 Not Cancer Driver No 122 0.134 554 70 0.126 0
EAPP EAPP Q56P03 E2F-associated phosphoprotein chr14 GO:0045934 Not Cancer Driver No 35 0.123 210 27 0.129 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 GO:0045934 Census Yes 77 0.189 27 14 0.519 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0045934 Not Cancer Driver No 116 0.118 899 101 0.112 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 GO:0045934 Not Cancer Driver No 69 0.212 43 5 0.116 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0045934 Not Cancer Driver No 118 0.306 117 34 0.291 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0045934 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0045934 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0045934 Not Cancer Driver No 211 0.141 829 117 0.141 9
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0045934 Census, Compendium Yes 121 0.203 195 27 0.138 2
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0045934 Not Cancer Driver No 87 0.098 375 35 0.093 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0045934 Census, Compendium Yes 120 0.161 284 44 0.155 11
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0045934 Not Cancer Driver No 99 0.133 206 20 0.097 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0045934 Not Cancer Driver No 33 0.098 19 0 0.0 4
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0045934 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLNA FLNA P21333 Filamin-A chrX GO:0045934 Census Yes 416 0.157 1456 214 0.147 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0045934 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0045934 Not Cancer Driver No 38 0.088 186 16 0.086 10
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0045934 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0045934 Not Cancer Driver No 57 0.096 476 51 0.107 10
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0045934 Not Cancer Driver No 67 0.088 434 42 0.097 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0045934 Not Cancer Driver No 120 0.206 242 43 0.178 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0045934 Not Cancer Driver No 55 0.114 180 8 0.044 0
GZMA GZMA P12544 Granzyme A chr5 GO:0045934 Not Cancer Driver No 70 0.267 5 1 0.2 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0045934 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0045934 Not Cancer Driver No 59 0.159 171 32 0.187 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0045934 Not Cancer Driver No 182 0.168 749 132 0.176 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0045934 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0045934 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0045934 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0045934 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0045934 Not Cancer Driver No 37 0.106 77 9 0.117 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0045934 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0045934 Not Cancer Driver No 25 0.116 203 20 0.099 0
HNRNPA0 HNRNPA0 Q13151 Heterogeneous nuclear ribonucleoprotein A0 chr5 GO:0045934 Not Cancer Driver No 25 0.082 172 14 0.081 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0045934 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0045934 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0045934 Not Cancer Driver No 31 0.093 202 11 0.054 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0045934 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0045934 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0045934 Not Cancer Driver No 75 0.162 302 59 0.195 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0045934 Not Cancer Driver No 77 0.093 504 45 0.089 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0045934 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0045934 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0045934 Not Cancer Driver No 24 0.037 200 13 0.065 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0045934 Not Cancer Driver No 20 0.129 17 6 0.353 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0045934 Not Cancer Driver No 141 0.244 298 80 0.268 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045934 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0045934 Not Cancer Driver No 49 0.153 84 12 0.143 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0045934 Census Yes 35 0.106 281 25 0.089 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0045934 Not Cancer Driver No 107 0.129 266 27 0.102 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0045934 Not Cancer Driver No 109 0.256 40 10 0.25 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:0045934 Not Cancer Driver No 131 0.113 387 48 0.124 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0045934 Census, Compendium Yes 446 0.112 3145 338 0.107 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0045934 Not Cancer Driver No 58 0.1 350 44 0.126 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0045934 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0045934 Not Cancer Driver No 60 0.24 179 32 0.179 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:0045934 Not Cancer Driver No 131 0.094 18 2 0.111 1
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0045934 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0045934 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0045934 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0045934 Not Cancer Driver No 43 0.107 92 5 0.054 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0045934 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEN1 MEN1 O00255 Menin chr11 GO:0045934 Census, Compendium Yes 73 0.119 228 15 0.066 90
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0045934 Census Yes 92 0.122 208 22 0.106 85
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0045934 Not Cancer Driver No 300 0.305 252 77 0.306 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0045934 Census Yes 40 0.032 1050 19 0.018 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0045934 Census, Compendium Yes 37 0.125 47 1 0.021 2
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0045934 Census Yes 67 0.128 395 51 0.129 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0045934 Not Cancer Driver No 24 0.041 238 10 0.042 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0045934 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0045934 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBAS NBAS A2RRP1 NBAS subunit of NRZ tethering complex chr2 GO:0045934 Not Cancer Driver No 365 0.154 246 41 0.167 5
NBN NBN O60934 Nibrin chr8 GO:0045934 Census Yes 90 0.119 417 54 0.129 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0045934 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0045934 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0045934 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 GO:0045934 Census, Compendium Yes 373 0.148 2355 356 0.151 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0045934 Not Cancer Driver No 22 0.1 44 4 0.091 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0045934 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0045934 Not Cancer Driver No 41 0.105 165 14 0.085 0
NELFA_ENST00000411638 NELFA Q9H3P2 Negative elongation factor A chr4 GO:0045934 Not Cancer Driver No 68 0.129 373 58 0.155 0
NELFCD NELFCD Q8IXH7 Negative elongation factor C/D chr20 GO:0045934 Not Cancer Driver No 69 0.117 53 1 0.019 0
NELFE NELFE P18615 Negative elongation factor E chr6 GO:0045934 Not Cancer Driver No 47 0.124 352 45 0.128 0
NFATC3 NFATC3 Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 chr16 GO:0045934 Not Cancer Driver No 112 0.104 730 80 0.11 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0045934 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0045934 Census Yes 63 0.15 254 36 0.142 3
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0045934 Not Cancer Driver No 59 0.123 391 41 0.105 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0045934 Not Cancer Driver No 10 0.079 82 6 0.073 0
NRDE2 NRDE2 Q9H7Z3 Nuclear exosome regulator NRDE2 chr14 GO:0045934 Not Cancer Driver No 135 0.116 373 50 0.134 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:0045934 Not Cancer Driver No 112 0.146 221 21 0.095 1
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0045934 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0045934 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0045934 Not Cancer Driver No 10 0.122 82 10 0.122 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0045934 Not Cancer Driver No 37 0.107 71 12 0.169 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0045934 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0045934 Not Cancer Driver No 67 0.14 259 36 0.139 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0045934 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0045934 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0045934 Not Cancer Driver No 70 0.131 269 38 0.141 0
PCBP4_ENST00000322099 PCBP4 P57723 Poly(rC)-binding protein 4 chr3 GO:0045934 Not Cancer Driver No 33 0.082 182 16 0.088 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0045934 Census Yes 37 0.154 99 22 0.222 2
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0045934 Not Cancer Driver No 58 0.102 199 19 0.095 0
PHAX PHAX Q9H814 Phosphorylated adapter RNA export protein chr5 GO:0045934 Not Cancer Driver No 32 0.081 331 29 0.088 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0045934 Not Cancer Driver No 37 0.136 4 1 0.25 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0045934 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0045934 Not Cancer Driver No 54 0.084 209 11 0.053 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0045934 Not Cancer Driver No 66 0.201 328 66 0.201 0
PKP1 PKP1 Q13835 Plakophilin-1 chr1 GO:0045934 Not Cancer Driver No 106 0.142 190 26 0.137 0
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 GO:0045934 Not Cancer Driver No 72 0.09 357 22 0.062 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0045934 Census, Compendium Yes 113 0.178 31 6 0.194 9
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:0045934 Census Yes 36 0.1 186 12 0.065 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0045934 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0045934 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0045934 Census Yes 72 0.143 44 4 0.091 3
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0045934 Compendium Yes 85 0.163 140 27 0.193 7
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0045934 Not Cancer Driver No 22 0.103 0 0 0.0 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0045934 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTBP2_ENST00000426398 PTBP2 Q9UKA9 Polypyrimidine tract-binding protein 2 chr1 GO:0045934 Not Cancer Driver No 84 0.158 136 20 0.147 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 GO:0045934 Not Cancer Driver No 61 0.111 114 9 0.079 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0045934 Not Cancer Driver No 157 0.12 730 84 0.115 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0045934 Census, Compendium Yes 70 0.152 167 14 0.084 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0045934 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX GO:0045934 Census, Compendium Yes 112 0.12 777 99 0.127 0
RBM42 RBM42 Q9BTD8 RNA-binding protein 42 chr19 GO:0045934 Not Cancer Driver No 78 0.163 338 48 0.142 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0045934 Not Cancer Driver No 82 0.21 380 81 0.213 0
RD3 RD3 Q7Z3Z2 Protein RD3 chr1 GO:0045934 Not Cancer Driver No 46 0.236 75 21 0.28 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0045934 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0045934 Compendium Yes 75 0.136 400 48 0.12 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0045934 Not Cancer Driver No 142 0.129 868 113 0.13 4
RGN RGN Q15493 Regucalcin chrX GO:0045934 Not Cancer Driver No 38 0.127 14 3 0.214 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0045934 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0045934 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0045934 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0045934 Not Cancer Driver No 56 0.115 226 29 0.128 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 GO:0045934 Not Cancer Driver No 30 0.098 305 30 0.098 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 GO:0045934 Not Cancer Driver No 19 0.126 18 5 0.278 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 GO:0045934 Not Cancer Driver No 9 0.078 52 5 0.096 2
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0045934 Not Cancer Driver No 144 0.118 474 64 0.135 14
SAP18_ENST00000607003 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 GO:0045934 Not Cancer Driver No 18 0.118 99 14 0.141 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 GO:0045934 Not Cancer Driver No 162 0.141 938 132 0.141 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0045934 Not Cancer Driver No 155 0.122 939 118 0.126 0
SECISBP2 SECISBP2 Q96T21 Selenocysteine insertion sequence-binding protein 2 chr9 GO:0045934 Not Cancer Driver No 90 0.105 565 50 0.088 1
SFSWAP_ENST00000261674 SFSWAP Q12872 Splicing factor, suppressor of white-apricot homolog chr12 GO:0045934 Not Cancer Driver No 137 0.144 769 111 0.144 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0045934 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHQ1 SHQ1 Q6PI26 Protein SHQ1 homolog chr3 GO:0045934 Not Cancer Driver No 66 0.114 199 20 0.101 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045934 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0045934 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0045934 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 GO:0045934 Not Cancer Driver No 7 0.064 41 3 0.073 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0045934 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0045934 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0045934 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0045934 Not Cancer Driver No 166 0.117 751 97 0.129 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0045934 Compendium Yes 86 0.169 495 82 0.166 18
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0045934 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0045934 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 GO:0045934 Not Cancer Driver No 2 0.008 192 1 0.005 0
SRSF12 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 GO:0045934 Not Cancer Driver No 36 0.138 205 31 0.151 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 GO:0045934 Not Cancer Driver No 67 0.136 409 55 0.134 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0045934 Not Cancer Driver No 69 0.201 259 49 0.189 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 GO:0045934 Not Cancer Driver No 40 0.168 175 26 0.149 0
SRSF9 SRSF9 Q13242 Serine/arginine-rich splicing factor 9 chr12 GO:0045934 Not Cancer Driver No 20 0.09 111 8 0.072 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0045934 Census, Compendium Yes 110 0.143 152 15 0.099 19
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0045934 Not Cancer Driver No 41 0.111 27 2 0.074 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0045934 Not Cancer Driver No 10 0.099 76 7 0.092 0
SUPT4H1_ENST00000580947 SUPT4H1 P63272 Transcription elongation factor SPT4 chr17 GO:0045934 Not Cancer Driver No 15 0.128 0 0 0.0 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:0045934 Not Cancer Driver No 165 0.152 572 87 0.152 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0045934 Not Cancer Driver No 93 0.149 285 39 0.137 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0045934 Not Cancer Driver No 51 0.123 202 15 0.074 27
TCERG1 TCERG1 O14776 Transcription elongation regulator 1 chr5 GO:0045934 Not Cancer Driver No 143 0.13 811 110 0.136 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0045934 Not Cancer Driver No 6 0.049 8 4 0.5 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0045934 Not Cancer Driver No 65 0.134 75 15 0.2 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0045934 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0045934 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0045934 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0045934 Not Cancer Driver No 28 0.07 310 16 0.052 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0045934 Census Yes 110 0.097 212 16 0.075 31
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0045934 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0045934 Not Cancer Driver No 87 0.104 331 39 0.118 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0045934 Not Cancer Driver No 41 0.105 41 4 0.098 10
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0045934 Not Cancer Driver No 55 0.084 280 26 0.093 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0045934 Not Cancer Driver No 69 0.141 207 30 0.145 2
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0045934 Not Cancer Driver No 44 0.163 39 9 0.231 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:0045934 Not Cancer Driver No 38 0.084 190 17 0.089 4
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0045934 Not Cancer Driver No 28 0.127 80 6 0.075 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0045934 Not Cancer Driver No 16 0.068 3 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045934 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0045934 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0045934 Not Cancer Driver No 117 0.1 255 24 0.094 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0045934 Not Cancer Driver No 35 0.101 214 18 0.084 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0045934 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRDMT1 TRDMT1 O14717 tRNA (cytosine(38)-C(5))-methyltransferase chr10 GO:0045934 Not Cancer Driver No 65 0.166 19 3 0.158 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0045934 Not Cancer Driver No 87 0.104 430 41 0.095 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 GO:0045934 Compendium Yes 78 0.164 191 28 0.147 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0045934 Census, Compendium Yes 142 0.667 117 36 0.308 133
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0045934 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0045934 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0045934 Not Cancer Driver No 213 0.125 577 65 0.113 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0045934 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0045934 Not Cancer Driver No 49 0.132 359 47 0.131 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0045934 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZC3H10 ZC3H10 Q96K80 Zinc finger CCCH domain-containing protein 10 chr12 GO:0045934 Not Cancer Driver No 41 0.094 336 31 0.092 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0045934 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H14 ZC3H14 Q6PJT7 Zinc finger CCCH domain-containing protein 14 chr14 GO:0045934 Not Cancer Driver No 96 0.13 542 68 0.125 0
ZCCHC17_ENST00000373714 ZCCHC17 Q9NP64 Zinc finger CCHC domain-containing protein 17 chr1 GO:0045934 Not Cancer Driver No 25 0.104 153 16 0.105 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0045934 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0045934 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF451 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 GO:0045934 Not Cancer Driver No 169 0.159 191 25 0.131 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 GO:0045934 Not Cancer Driver No 101 0.113 694 83 0.12 0
ZNF91 ZNF91 Q05481 Zinc finger protein 91 chr19 GO:0045934 Not Cancer Driver No 317 0.266 128 24 0.188 0
ZNF93 ZNF93 P35789 Zinc finger protein 93 chr19 GO:0045934 Compendium Yes 101 0.163 73 18 0.247 0
ZSCAN4_ENST00000612521 ZSCAN4 Q8NAM6 Zinc finger and SCAN domain-containing protein 4 chr19 GO:0045934 Not Cancer Driver No 108 0.249 249 58 0.233 0