Total number of protein in "GO:0045786" GO term: 168
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCYAP1_ENST00000450565 | ADCYAP1 | P18509 | Pituitary adenylate cyclase-activating polypeptide | chr18 | GO:0045786 | Not Cancer Driver | No | 43 | 0.244 | 75 | 11 | 0.147 | 0 |
| ALOX15B | ALOX15B | O15296 | Polyunsaturated fatty acid lipoxygenase ALOX15B | chr17 | GO:0045786 | Not Cancer Driver | No | 99 | 0.146 | 62 | 12 | 0.194 | 0 |
| APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | GO:0045786 | Not Cancer Driver | No | 105 | 0.148 | 399 | 58 | 0.145 | 0 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0045786 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0045786 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0045786 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | GO:0045786 | Not Cancer Driver | No | 51 | 0.148 | 63 | 8 | 0.127 | 0 |
| BAZ1B_ENST00000404251 | BAZ1B | Q9UIG0 | Tyrosine-protein kinase BAZ1B | chr7 | GO:0045786 | Not Cancer Driver | No | 153 | 0.103 | 840 | 87 | 0.104 | 0 |
| BCL6_ENST00000232014 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0045786 | Census, Compendium | Yes | 134 | 0.19 | 328 | 67 | 0.204 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0045786 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0045786 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0045786 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0045786 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
| BRINP1 | BRINP1 | O60477 | BMP/retinoic acid-inducible neural-specific protein 1 | chr9 | GO:0045786 | Not Cancer Driver | No | 273 | 0.359 | 36 | 17 | 0.472 | 0 |
| C10orf99 | GPR15L | Q6UWK7 | Protein GPR15L | chr10 | GO:0045786 | Not Cancer Driver | No | 11 | 0.136 | 0 | 0 | 0.0 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0045786 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0045786 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0045786 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCNF | CCNF | P41002 | Cyclin-F | chr16 | GO:0045786 | Not Cancer Driver | No | 106 | 0.135 | 221 | 23 | 0.104 | 3 |
| CCP110 | CCP110 | O43303 | Centriolar coiled-coil protein of 110 kDa | chr16 | GO:0045786 | Not Cancer Driver | No | 94 | 0.093 | 679 | 61 | 0.09 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0045786 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0045786 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CDK5RAP1_ENST00000357886 | CDK5RAP1 | Q96SZ6 | Mitochondrial tRNA methylthiotransferase CDK5RAP1 | chr20 | GO:0045786 | Not Cancer Driver | No | 73 | 0.121 | 95 | 12 | 0.126 | 0 |
| CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0045786 | Not Cancer Driver | No | 217 | 0.115 | 1136 | 128 | 0.113 | 0 |
| CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0045786 | Census | Yes | 40 | 0.123 | 24 | 3 | 0.125 | 1 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0045786 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0045786 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0045786 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0045786 | Census, Compendium | Yes | 166 | 1.064 | 83 | 88 | 1.06 | 36 |
| CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0045786 | Not Cancer Driver | No | 15 | 0.109 | 67 | 3 | 0.045 | 0 |
| CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:0045786 | Census, Compendium | Yes | 23 | 0.137 | 49 | 6 | 0.122 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0045786 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CDT1 | CDT1 | Q9H211 | DNA replication factor Cdt1 | chr16 | GO:0045786 | Not Cancer Driver | No | 60 | 0.11 | 377 | 35 | 0.093 | 5 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0045786 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0045786 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0045786 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
| CHFR | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0045786 | Not Cancer Driver | No | 85 | 0.128 | 341 | 54 | 0.158 | 0 |
| CHMP2A_ENST00000601220 | CHMP2A | O43633 | Charged multivesicular body protein 2a | chr19 | GO:0045786 | Not Cancer Driver | No | 29 | 0.131 | 161 | 22 | 0.137 | 0 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | GO:0045786 | Not Cancer Driver | No | 33 | 0.142 | 224 | 31 | 0.138 | 0 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0045786 | Not Cancer Driver | No | 35 | 0.176 | 45 | 5 | 0.111 | 1 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0045786 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0045786 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DMRT1 | DMRT1 | Q9Y5R6 | Doublesex- and mab-3-related transcription factor 1 | chr9 | GO:0045786 | Not Cancer Driver | No | 60 | 0.161 | 282 | 47 | 0.167 | 0 |
| DUSP1 | DUSP1 | P28562 | Dual specificity protein phosphatase 1 | chr5 | GO:0045786 | Not Cancer Driver | No | 31 | 0.084 | 7 | 0 | 0.0 | 0 |
| E2F7 | E2F7 | Q96AV8 | Transcription factor E2F7 | chr12 | GO:0045786 | Not Cancer Driver | No | 122 | 0.134 | 554 | 70 | 0.126 | 0 |
| E2F8_ENST00000250024 | E2F8 | A0AVK6 | Transcription factor E2F8 | chr11 | GO:0045786 | Not Cancer Driver | No | 132 | 0.152 | 582 | 85 | 0.146 | 0 |
| EEF1AKNMT | METTL13 | Q8N6R0 | eEF1A lysine and N-terminal methyltransferase | chr1 | GO:0045786 | Not Cancer Driver | No | 91 | 0.13 | 76 | 16 | 0.211 | 0 |
| ESPL1 | ESPL1 | Q14674 | Separin | chr12 | GO:0045786 | Not Cancer Driver | No | 211 | 0.1 | 380 | 39 | 0.103 | 0 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0045786 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FBXO43 | FBXO43 | Q4G163 | F-box only protein 43 | chr8 | GO:0045786 | Not Cancer Driver | No | 98 | 0.138 | 292 | 40 | 0.137 | 0 |
| FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | GO:0045786 | Not Cancer Driver | No | 48 | 0.107 | 113 | 13 | 0.115 | 0 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | GO:0045786 | Not Cancer Driver | No | 75 | 0.144 | 243 | 38 | 0.156 | 1 |
| FOXO4 | FOXO4 | P98177 | Forkhead box protein O4 | chrX | GO:0045786 | Census | Yes | 75 | 0.149 | 441 | 61 | 0.138 | 0 |
| FZD3_ENST00000240093 | FZD3 | Q9NPG1 | Frizzled-3 | chr8 | GO:0045786 | Not Cancer Driver | No | 64 | 0.096 | 141 | 13 | 0.092 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0045786 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0045786 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
| GML | GML | Q99445 | Glycosyl-phosphatidylinositol-anchored molecule-like protein | chr8 | GO:0045786 | Not Cancer Driver | No | 49 | 0.31 | 12 | 6 | 0.5 | 0 |
| GMNC | GMNC | A6NCL1 | Geminin coiled-coil domain-containing protein 1 | chr3 | GO:0045786 | Not Cancer Driver | No | 13 | 0.039 | 203 | 9 | 0.044 | 0 |
| GMNN_ENST00000620958 | GMNN | O75496 | Geminin | chr6 | GO:0045786 | Not Cancer Driver | No | 24 | 0.115 | 206 | 24 | 0.117 | 1 |
| GTSE1 | GTSE1 | Q9NYZ3 | G2 and S phase-expressed protein 1 | chr22 | GO:0045786 | Not Cancer Driver | No | 91 | 0.126 | 660 | 85 | 0.129 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:0045786 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
| HEXIM2_ENST00000592695 | HEXIM2 | Q96MH2 | Protein HEXIM2 | chr17 | GO:0045786 | Not Cancer Driver | No | 35 | 0.122 | 286 | 35 | 0.122 | 0 |
| HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0045786 | Not Cancer Driver | No | 23 | 0.085 | 193 | 21 | 0.109 | 0 |
| HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0045786 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
| HORMAD1 | HORMAD1 | Q86X24 | HORMA domain-containing protein 1 | chr1 | GO:0045786 | Not Cancer Driver | No | 76 | 0.193 | 178 | 31 | 0.174 | 0 |
| HPGD | HPGD | P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | chr4 | GO:0045786 | Not Cancer Driver | No | 32 | 0.12 | 4 | 1 | 0.25 | 2 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0045786 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| HUS1 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | GO:0045786 | Not Cancer Driver | No | 25 | 0.089 | 17 | 2 | 0.118 | 0 |
| HUS1B | HUS1B | Q8NHY5 | Checkpoint protein HUS1B | chr6 | GO:0045786 | Not Cancer Driver | No | 50 | 0.18 | 10 | 1 | 0.1 | 0 |
| INCA1_ENST00000576820 | INCA1 | Q0VD86 | Protein INCA1 | chr17 | GO:0045786 | Not Cancer Driver | No | 18 | 0.076 | 195 | 14 | 0.072 | 0 |
| INHA | INHA | P05111 | Inhibin alpha chain | chr2 | GO:0045786 | Not Cancer Driver | No | 48 | 0.131 | 144 | 15 | 0.104 | 0 |
| IPO5_ENST00000490680 | IPO5 | O00410 | Importin-5 | chr13 | GO:0045786 | Not Cancer Driver | No | 128 | 0.117 | 52 | 3 | 0.058 | 0 |
| IPO7 | IPO7 | O95373 | Importin-7 | chr11 | GO:0045786 | Not Cancer Driver | No | 138 | 0.133 | 202 | 30 | 0.149 | 0 |
| KAT2A | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | GO:0045786 | Not Cancer Driver | No | 88 | 0.105 | 251 | 17 | 0.068 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0045786 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
| KIF25_ENST00000443060 | KIF25 | Q9UIL4 | Kinesin-like protein KIF25 | chr6 | GO:0045786 | Not Cancer Driver | No | 80 | 0.208 | 143 | 37 | 0.259 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0045786 | Census, Compendium | Yes | 161 | 0.142 | 788 | 100 | 0.127 | 0 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | GO:0045786 | Census, Compendium | Yes | 178 | 0.164 | 687 | 116 | 0.169 | 0 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0045786 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| LILRB1_ENST00000396331 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0045786 | Not Cancer Driver | No | 203 | 0.312 | 291 | 97 | 0.333 | 0 |
| MAD2L1BP_ENST00000372171 | MAD2L1BP | Q15013 | MAD2L1-binding protein | chr6 | GO:0045786 | Not Cancer Driver | No | 26 | 0.095 | 55 | 7 | 0.127 | 0 |
| MAPK12 | MAPK12 | P53778 | Mitogen-activated protein kinase 12 | chr22 | GO:0045786 | Not Cancer Driver | No | 31 | 0.084 | 63 | 5 | 0.079 | 0 |
| MCIDAS | MCIDAS | D6RGH6 | Multicilin | chr5 | GO:0045786 | Not Cancer Driver | No | 4 | 0.01 | 269 | 4 | 0.015 | 2 |
| MDM1 | MDM1 | Q8TC05 | Nuclear protein MDM1 | chr12 | GO:0045786 | Not Cancer Driver | No | 105 | 0.147 | 661 | 101 | 0.153 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0045786 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MEIOC | MEIOC | A2RUB1 | Meiosis-specific coiled-coil domain-containing protein MEIOC | chr17 | GO:0045786 | Not Cancer Driver | No | 92 | 0.097 | 529 | 54 | 0.102 | 0 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0045786 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MOS | MOS | P00540 | Proto-oncogene serine/threonine-protein kinase mos | chr8 | GO:0045786 | Not Cancer Driver | No | 94 | 0.272 | 16 | 4 | 0.25 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:0045786 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| MYOCD_ENST00000343344 | MYOCD | Q8IZQ8 | Myocardin | chr17 | GO:0045786 | Not Cancer Driver | No | 284 | 0.303 | 853 | 263 | 0.308 | 0 |
| NAA10 | NAA10 | P41227 | N-alpha-acetyltransferase 10 | chrX | GO:0045786 | Not Cancer Driver | No | 33 | 0.14 | 117 | 17 | 0.145 | 3 |
| NACC2_ENST00000371753 | NACC2 | Q96BF6 | Nucleus accumbens-associated protein 2 | chr9 | GO:0045786 | Not Cancer Driver | No | 24 | 0.041 | 238 | 10 | 0.042 | 0 |
| NANOS2 | NANOS2 | P60321 | Nanos homolog 2 | chr19 | GO:0045786 | Not Cancer Driver | No | 29 | 0.21 | 50 | 11 | 0.22 | 0 |
| NEK2 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | GO:0045786 | Not Cancer Driver | No | 61 | 0.137 | 92 | 19 | 0.207 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0045786 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0045786 | Census, Compendium | Yes | 29 | 0.099 | 249 | 22 | 0.088 | 0 |
| NPPC | NPPC | P23582 | C-type natriuretic peptide | chr2 | GO:0045786 | Not Cancer Driver | No | 10 | 0.079 | 82 | 6 | 0.073 | 0 |
| NPR2 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0045786 | Not Cancer Driver | No | 144 | 0.138 | 89 | 18 | 0.202 | 20 |
| NR2F2 | NR2F2 | P24468 | COUP transcription factor 2 | chr15 | GO:0045786 | Not Cancer Driver | No | 66 | 0.159 | 101 | 1 | 0.01 | 5 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0045786 | Not Cancer Driver | No | 62 | 0.104 | 252 | 24 | 0.095 | 0 |
| NSUN2 | NSUN2 | Q08J23 | RNA cytosine C(5)-methyltransferase NSUN2 | chr5 | GO:0045786 | Not Cancer Driver | No | 112 | 0.146 | 221 | 21 | 0.095 | 1 |
| NUBP1 | NUBP1 | P53384 | Cytosolic Fe-S cluster assembly factor NUBP1 | chr16 | GO:0045786 | Not Cancer Driver | No | 31 | 0.097 | 62 | 6 | 0.097 | 0 |
| NUDT6 | NUDT6 | P53370 | Nucleoside diphosphate-linked moiety X motif 6 | chr4 | GO:0045786 | Not Cancer Driver | No | 40 | 0.127 | 14 | 0 | 0.0 | 0 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0045786 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| NUPR2 | NUPR2 | A6NF83 | Nuclear protein 2 | chr7 | GO:0045786 | Not Cancer Driver | No | 3 | 0.031 | 76 | 3 | 0.039 | 0 |
| OVOL1 | OVOL1 | O14753 | Putative transcription factor Ovo-like 1 | chr11 | GO:0045786 | Not Cancer Driver | No | 31 | 0.116 | 69 | 9 | 0.13 | 0 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0045786 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PIDD1 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0045786 | Not Cancer Driver | No | 93 | 0.102 | 137 | 14 | 0.102 | 0 |
| PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0045786 | Not Cancer Driver | No | 87 | 0.144 | 119 | 13 | 0.109 | 0 |
| PLK2 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0045786 | Not Cancer Driver | No | 92 | 0.134 | 178 | 21 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0045786 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PLK5 | PLK5 | Q496M5 | Inactive serine/threonine-protein kinase PLK5 | chr19 | GO:0045786 | Not Cancer Driver | No | 8 | 0.024 | 215 | 4 | 0.019 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0045786 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPP1R10 | PPP1R10 | Q96QC0 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | chr6 | GO:0045786 | Not Cancer Driver | No | 114 | 0.121 | 798 | 100 | 0.125 | 0 |
| PPP1R13B | PPP1R13B | Q96KQ4 | Apoptosis-stimulating of p53 protein 1 | chr14 | GO:0045786 | Not Cancer Driver | No | 115 | 0.106 | 821 | 92 | 0.112 | 0 |
| PPP2R5B | PPP2R5B | Q15173 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform | chr11 | GO:0045786 | Not Cancer Driver | No | 79 | 0.159 | 119 | 9 | 0.076 | 0 |
| PRAP1 | PRAP1 | Q96NZ9 | Proline-rich acidic protein 1 | chr10 | GO:0045786 | Not Cancer Driver | No | 14 | 0.093 | 124 | 13 | 0.105 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0045786 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0045786 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0045786 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| PTPRK_ENST00000368215 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0045786 | Census, Compendium | Yes | 292 | 0.203 | 302 | 57 | 0.189 | 0 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0045786 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0045786 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | GO:0045786 | Not Cancer Driver | No | 99 | 0.148 | 350 | 59 | 0.169 | 0 |
| RFWD3 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0045786 | Census | Yes | 68 | 0.088 | 318 | 30 | 0.094 | 1 |
| RGCC | RGCC | Q9H4X1 | Regulator of cell cycle RGCC | chr13 | GO:0045786 | Not Cancer Driver | No | 9 | 0.066 | 81 | 7 | 0.086 | 0 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | GO:0045786 | Not Cancer Driver | No | 52 | 0.265 | 19 | 2 | 0.105 | 0 |
| RNF167_ENST00000571816 | RNF167 | Q9H6Y7 | E3 ubiquitin-protein ligase RNF167 | chr17 | GO:0045786 | Not Cancer Driver | No | 35 | 0.1 | 102 | 18 | 0.176 | 0 |
| RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0045786 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:0045786 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0045786 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| RPS6KA2_ENST00000265678 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | GO:0045786 | Not Cancer Driver | No | 133 | 0.181 | 91 | 15 | 0.165 | 0 |
| RRP8 | RRP8 | O43159 | Ribosomal RNA-processing protein 8 | chr11 | GO:0045786 | Not Cancer Driver | No | 66 | 0.145 | 270 | 44 | 0.163 | 0 |
| RUNX3_ENST00000308873 | RUNX3 | Q13761 | Runt-related transcription factor 3 | chr1 | GO:0045786 | Not Cancer Driver | No | 59 | 0.142 | 331 | 45 | 0.136 | 0 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | GO:0045786 | Not Cancer Driver | No | 56 | 0.124 | 290 | 35 | 0.121 | 0 |
| SIPA1_ENST00000534313 | SIPA1 | Q96FS4 | Signal-induced proliferation-associated protein 1 | chr11 | GO:0045786 | Not Cancer Driver | No | 67 | 0.064 | 666 | 43 | 0.065 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0045786 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | GO:0045786 | Not Cancer Driver | No | 116 | 0.11 | 363 | 48 | 0.132 | 0 |
| SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | GO:0045786 | Census | Yes | 39 | 0.123 | 312 | 39 | 0.125 | 0 |
| SUSD2 | SUSD2 | Q9UGT4 | Sushi domain-containing protein 2 | chr22 | GO:0045786 | Compendium | Yes | 113 | 0.137 | 133 | 22 | 0.165 | 0 |
| SUV39H1_ENST00000376687 | SUV39H1 | O43463 | Histone-lysine N-methyltransferase SUV39H1 | chrX | GO:0045786 | Not Cancer Driver | No | 59 | 0.143 | 15 | 1 | 0.067 | 0 |
| TAF6_ENST00000344095 | TAF6 | P49848 | Transcription initiation factor TFIID subunit 6 | chr7 | GO:0045786 | Not Cancer Driver | No | 79 | 0.117 | 288 | 32 | 0.111 | 2 |
| TENT5B | TENT5B | Q96A09 | Terminal nucleotidyltransferase 5B | chr1 | GO:0045786 | Not Cancer Driver | No | 52 | 0.122 | 57 | 6 | 0.105 | 0 |
| TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | GO:0045786 | Not Cancer Driver | No | 63 | 0.144 | 220 | 34 | 0.155 | 0 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | GO:0045786 | Not Cancer Driver | No | 33 | 0.061 | 361 | 20 | 0.055 | 0 |
| TEX14 | TEX14 | Q8IWB6 | Inactive serine/threonine-protein kinase TEX14 | chr17 | GO:0045786 | Not Cancer Driver | No | 214 | 0.143 | 872 | 115 | 0.132 | 0 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0045786 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0045786 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| THAP5 | THAP5 | Q7Z6K1 | THAP domain-containing protein 5 | chr7 | GO:0045786 | Not Cancer Driver | No | 42 | 0.106 | 218 | 25 | 0.115 | 0 |
| TMEM67 | TMEM67 | Q5HYA8 | Meckelin | chr8 | GO:0045786 | Not Cancer Driver | No | 120 | 0.121 | 11 | 0 | 0.0 | 37 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0045786 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:0045786 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
| TP53BP2 | TP53BP2 | Q13625 | Apoptosis-stimulating of p53 protein 2 | chr1 | GO:0045786 | Not Cancer Driver | No | 152 | 0.135 | 868 | 118 | 0.136 | 0 |
| TP53I13 | TP53I13 | Q8NBR0 | Tumor protein p53-inducible protein 13 | chr17 | GO:0045786 | Not Cancer Driver | No | 38 | 0.097 | 231 | 25 | 0.108 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0045786 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0045786 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0045786 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | GO:0045786 | Not Cancer Driver | No | 119 | 0.123 | 492 | 60 | 0.122 | 3 |
| TRIP13 | TRIP13 | Q15645 | Pachytene checkpoint protein 2 homolog | chr5 | GO:0045786 | Not Cancer Driver | No | 62 | 0.144 | 30 | 6 | 0.2 | 1 |
| TSPYL2 | TSPYL2 | Q9H2G4 | Testis-specific Y-encoded-like protein 2 | chrX | GO:0045786 | Not Cancer Driver | No | 80 | 0.115 | 509 | 55 | 0.108 | 0 |
| TTK | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | GO:0045786 | Not Cancer Driver | No | 136 | 0.159 | 352 | 46 | 0.131 | 0 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | GO:0045786 | Not Cancer Driver | No | 48 | 0.11 | 167 | 17 | 0.102 | 4 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0045786 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| WAPL_ENST00000618527 | WAPL | Q7Z5K2 | Wings apart-like protein homolog | chr10 | GO:0045786 | Not Cancer Driver | No | 140 | 0.118 | 621 | 68 | 0.11 | 0 |
| WEE2 | WEE2 | P0C1S8 | Wee1-like protein kinase 2 | chr7 | GO:0045786 | Not Cancer Driver | No | 104 | 0.183 | 345 | 65 | 0.188 | 1 |
| YTHDC2 | YTHDC2 | Q9H6S0 | 3'-5' RNA helicase YTHDC2 | chr5 | GO:0045786 | Not Cancer Driver | No | 163 | 0.114 | 439 | 48 | 0.109 | 0 |
| ZBTB17_ENST00000375743 | ZBTB17 | Q13105 | Zinc finger and BTB domain-containing protein 17 | chr1 | GO:0045786 | Not Cancer Driver | No | 77 | 0.096 | 310 | 30 | 0.097 | 0 |
| ZFYVE19 | ZFYVE19 | Q96K21 | Abscission/NoCut checkpoint regulator | chr15 | GO:0045786 | Not Cancer Driver | No | 41 | 0.087 | 361 | 28 | 0.078 | 0 |