Total number of protein in "GO:0045785" GO term: 331
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0045785 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0045785 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
ADAM19_ENST00000517905 | ADAM19 | Q9H013 | Disintegrin and metalloproteinase domain-containing protein 19 | chr5 | GO:0045785 | Not Cancer Driver | No | 172 | 0.18 | 370 | 77 | 0.208 | 0 |
ADAM8 | ADAM8 | P78325 | Disintegrin and metalloproteinase domain-containing protein 8 | chr10 | GO:0045785 | Not Cancer Driver | No | 82 | 0.1 | 230 | 13 | 0.057 | 0 |
ADAM9 | ADAM9 | Q13443 | Disintegrin and metalloproteinase domain-containing protein 9 | chr8 | GO:0045785 | Not Cancer Driver | No | 86 | 0.105 | 129 | 13 | 0.101 | 0 |
ADGRG1 | ADGRG1 | Q9Y653 | Adhesion G-protein coupled receptor G1 | chr16 | GO:0045785 | Not Cancer Driver | No | 64 | 0.092 | 67 | 4 | 0.06 | 9 |
AFDN_ENST00000447894 | AFDN | P55196 | Afadin | chr6 | GO:0045785 | Census | Yes | 248 | 0.136 | 1247 | 180 | 0.144 | 0 |
AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0045785 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0045785 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
ALOX5 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0045785 | Not Cancer Driver | No | 129 | 0.191 | 16 | 2 | 0.125 | 0 |
AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0045785 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0045785 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:0045785 | Not Cancer Driver | No | 860 | 0.196 | 3054 | 579 | 0.19 | 0 |
ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0045785 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
AP3B1 | AP3B1 | O00203 | AP-3 complex subunit beta-1 | chr5 | GO:0045785 | Not Cancer Driver | No | 126 | 0.115 | 316 | 31 | 0.098 | 1 |
AP3D1_ENST00000345016 | AP3D1 | O14617 | AP-3 complex subunit delta-1 | chr19 | GO:0045785 | Not Cancer Driver | No | 138 | 0.12 | 404 | 59 | 0.146 | 0 |
APBB1IP | APBB1IP | Q7Z5R6 | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein | chr10 | GO:0045785 | Not Cancer Driver | No | 130 | 0.195 | 396 | 60 | 0.152 | 0 |
APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0045785 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0045785 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
ARPC2_ENST00000315717 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | GO:0045785 | Not Cancer Driver | No | 40 | 0.133 | 49 | 8 | 0.163 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0045785 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
AZU1 | AZU1 | P20160 | Azurocidin | chr19 | GO:0045785 | Not Cancer Driver | No | 42 | 0.167 | 53 | 13 | 0.245 | 0 |
BAG4 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | GO:0045785 | Not Cancer Driver | No | 55 | 0.12 | 402 | 49 | 0.122 | 0 |
BCL6_ENST00000232014 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0045785 | Census, Compendium | Yes | 134 | 0.19 | 328 | 67 | 0.204 | 0 |
BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0045785 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
BTN2A2 | BTN2A2 | Q8WVV5 | Butyrophilin subfamily 2 member A2 | chr6 | GO:0045785 | Not Cancer Driver | No | 92 | 0.176 | 24 | 2 | 0.083 | 0 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0045785 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
CALR | CALR | P27797 | Calreticulin | chr19 | GO:0045785 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
CARD11 | CARD11 | Q9BXL7 | Caspase recruitment domain-containing protein 11 | chr7 | GO:0045785 | Census, Compendium | Yes | 303 | 0.263 | 530 | 140 | 0.264 | 5 |
CARMIL1 | CARMIL1 | Q5VZK9 | F-actin-uncapping protein LRRC16A | chr6 | GO:0045785 | Not Cancer Driver | No | 171 | 0.125 | 537 | 87 | 0.162 | 0 |
CASS4 | CASS4 | Q9NQ75 | Cas scaffolding protein family member 4 | chr20 | GO:0045785 | Not Cancer Driver | No | 204 | 0.26 | 496 | 137 | 0.276 | 0 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0045785 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
CBFB_ENST00000290858 | CBFB | Q13951 | Core-binding factor subunit beta | chr16 | GO:0045785 | Census, Compendium | Yes | 39 | 0.214 | 94 | 17 | 0.181 | 0 |
CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0045785 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0045785 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
CCL25 | CCL25 | O15444 | C-C motif chemokine 25 | chr19 | GO:0045785 | Not Cancer Driver | No | 20 | 0.133 | 26 | 6 | 0.231 | 0 |
CCL28 | CCL28 | Q9NRJ3 | C-C motif chemokine 28 | chr5 | GO:0045785 | Not Cancer Driver | No | 17 | 0.134 | 48 | 8 | 0.167 | 0 |
CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0045785 | Not Cancer Driver | No | 81 | 0.217 | 23 | 1 | 0.043 | 0 |
CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0045785 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
CD160_ENST00000369288 | CD160 | O95971 | CD160 antigen | chr1 | GO:0045785 | Not Cancer Driver | No | 20 | 0.11 | 2 | 0 | 0.0 | 0 |
CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | GO:0045785 | Census | Yes | 29 | 0.1 | 54 | 9 | 0.167 | 0 |
CD28 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0045785 | Census | Yes | 42 | 0.191 | 18 | 10 | 0.556 | 0 |
CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0045785 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0045785 | Not Cancer Driver | No | 28 | 0.135 | 72 | 12 | 0.167 | 0 |
CD40LG | CD40LG | P29965 | CD40 ligand | chrX | GO:0045785 | Not Cancer Driver | No | 56 | 0.215 | 24 | 7 | 0.292 | 32 |
CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:0045785 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
CD46_ENST00000358170 | CD46 | P15529 | Membrane cofactor protein | chr1 | GO:0045785 | Not Cancer Driver | No | 53 | 0.135 | 52 | 4 | 0.077 | 5 |
CD5 | CD5 | P06127 | T-cell surface glycoprotein CD5 | chr11 | GO:0045785 | Not Cancer Driver | No | 67 | 0.135 | 146 | 19 | 0.13 | 0 |
CD55_ENST00000367064 | CD55 | P08174 | Complement decay-accelerating factor | chr1 | GO:0045785 | Not Cancer Driver | No | 45 | 0.118 | 128 | 13 | 0.102 | 1 |
CD80_ENST00000478182 | CD80 | P33681 | T-lymphocyte activation antigen CD80 | chr3 | GO:0045785 | Not Cancer Driver | No | 50 | 0.174 | 26 | 5 | 0.192 | 0 |
CD81 | CD81 | P60033 | CD81 antigen | chr11 | GO:0045785 | Not Cancer Driver | No | 28 | 0.119 | 0 | 0 | 0.0 | 0 |
CD83 | CD83 | Q01151 | CD83 antigen | chr6 | GO:0045785 | Not Cancer Driver | No | 24 | 0.117 | 48 | 8 | 0.167 | 0 |
CD86 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0045785 | Not Cancer Driver | No | 90 | 0.274 | 56 | 18 | 0.321 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0045785 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0045785 | Not Cancer Driver | No | 168 | 0.236 | 235 | 59 | 0.251 | 0 |
CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0045785 | Census | Yes | 40 | 0.123 | 24 | 3 | 0.125 | 1 |
CEACAM6 | CEACAM6 | P40199 | Carcinoembryonic antigen-related cell adhesion molecule 6 | chr19 | GO:0045785 | Not Cancer Driver | No | 63 | 0.183 | 110 | 19 | 0.173 | 0 |
CHRD | CHRD | Q9H2X0 | Chordin | chr3 | GO:0045785 | Not Cancer Driver | No | 171 | 0.179 | 308 | 61 | 0.198 | 0 |
CHST2 | CHST2 | Q9Y4C5 | Carbohydrate sulfotransferase 2 | chr3 | GO:0045785 | Not Cancer Driver | No | 98 | 0.185 | 136 | 11 | 0.081 | 0 |
CHST4_ENST00000539698 | CHST4 | Q8NCG5 | Carbohydrate sulfotransferase 4 | chr16 | GO:0045785 | Not Cancer Driver | No | 59 | 0.153 | 7 | 0 | 0.0 | 0 |
CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0045785 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
COL16A1 | COL16A1 | Q07092 | Collagen alpha-1(XVI) chain | chr1 | GO:0045785 | Not Cancer Driver | No | 192 | 0.12 | 1381 | 163 | 0.118 | 0 |
CR1_ENST00000367053 | CR1 | P17927 | Complement receptor type 1 | chr1 | GO:0045785 | Compendium | Yes | 383 | 0.188 | 151 | 42 | 0.278 | 0 |
CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0045785 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0045785 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0045785 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
CSK_ENST00000439220 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | GO:0045785 | Not Cancer Driver | No | 41 | 0.091 | 18 | 1 | 0.056 | 0 |
CSPG5 | CSPG5 | O95196 | Chondroitin sulfate proteoglycan 5 | chr3 | GO:0045785 | Not Cancer Driver | No | 75 | 0.133 | 397 | 46 | 0.116 | 0 |
CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0045785 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0045785 | Not Cancer Driver | No | 66 | 0.166 | 259 | 44 | 0.17 | 0 |
CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0045785 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
CXCL13 | CXCL13 | O43927 | C-X-C motif chemokine 13 | chr4 | GO:0045785 | Not Cancer Driver | No | 11 | 0.101 | 0 | 0 | 0.0 | 0 |
CYTH3_ENST00000396741 | CYTH3 | O43739 | Cytohesin-3 | chr7 | GO:0045785 | Not Cancer Driver | No | 49 | 0.122 | 96 | 12 | 0.125 | 0 |
DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0045785 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0045785 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
DENND6A | DENND6A | Q8IWF6 | Protein DENND6A | chr3 | GO:0045785 | Not Cancer Driver | No | 54 | 0.089 | 69 | 2 | 0.029 | 0 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | GO:0045785 | Not Cancer Driver | No | 132 | 0.155 | 514 | 82 | 0.16 | 0 |
DMTN_ENST00000358242 | DMTN | Q08495 | Dematin | chr8 | GO:0045785 | Not Cancer Driver | No | 53 | 0.131 | 348 | 46 | 0.132 | 0 |
DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0045785 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
DOCK1_ENST00000280333 | DOCK1 | Q14185 | Dedicator of cytokinesis protein 1 | chr10 | GO:0045785 | Not Cancer Driver | No | 240 | 0.129 | 360 | 52 | 0.144 | 0 |
DOCK5 | DOCK5 | Q9H7D0 | Dedicator of cytokinesis protein 5 | chr8 | GO:0045785 | Not Cancer Driver | No | 278 | 0.149 | 330 | 45 | 0.136 | 0 |
DOCK8 | DOCK8 | Q8NF50 | Dedicator of cytokinesis protein 8 | chr9 | GO:0045785 | Not Cancer Driver | No | 321 | 0.153 | 312 | 60 | 0.192 | 1 |
DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0045785 | Not Cancer Driver | No | 151 | 0.197 | 8 | 1 | 0.125 | 0 |
DUSP10 | DUSP10 | Q9Y6W6 | Dual specificity protein phosphatase 10 | chr1 | GO:0045785 | Not Cancer Driver | No | 81 | 0.168 | 135 | 24 | 0.178 | 0 |
DUSP26 | DUSP26 | Q9BV47 | Dual specificity protein phosphatase 26 | chr8 | GO:0045785 | Not Cancer Driver | No | 56 | 0.265 | 14 | 6 | 0.429 | 0 |
EBI3 | EBI3 | Q14213 | Interleukin-27 subunit beta | chr19 | GO:0045785 | Not Cancer Driver | No | 32 | 0.14 | 10 | 1 | 0.1 | 0 |
EFEMP2 | EFEMP2 | O95967 | EGF-containing fibulin-like extracellular matrix protein 2 | chr11 | GO:0045785 | Not Cancer Driver | No | 67 | 0.151 | 41 | 4 | 0.098 | 8 |
EFNB1 | EFNB1 | P98172 | Ephrin-B1 | chrX | GO:0045785 | Not Cancer Driver | No | 46 | 0.133 | 126 | 14 | 0.111 | 19 |
EFNB2_ENST00000245323 | EFNB2 | P52799 | Ephrin-B2 | chr13 | GO:0045785 | Not Cancer Driver | No | 42 | 0.126 | 97 | 15 | 0.155 | 0 |
EFNB3 | EFNB3 | Q15768 | Ephrin-B3 | chr17 | GO:0045785 | Not Cancer Driver | No | 45 | 0.132 | 183 | 22 | 0.12 | 0 |
EGR3 | EGR3 | Q06889 | Early growth response protein 3 | chr8 | GO:0045785 | Not Cancer Driver | No | 60 | 0.155 | 252 | 46 | 0.183 | 0 |
ELANE_ENST00000263621 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0045785 | Not Cancer Driver | No | 39 | 0.146 | 18 | 3 | 0.167 | 89 |
EMILIN2 | EMILIN2 | Q9BXX0 | EMILIN-2 | chr18 | GO:0045785 | Not Cancer Driver | No | 158 | 0.15 | 617 | 94 | 0.152 | 0 |
EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0045785 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
EPB41L4B | EPB41L4B | Q9H329 | Band 4.1-like protein 4B | chr9 | GO:0045785 | Not Cancer Driver | No | 131 | 0.146 | 548 | 77 | 0.141 | 0 |
EPB41L5 | EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | chr2 | GO:0045785 | Not Cancer Driver | No | 97 | 0.132 | 312 | 45 | 0.144 | 0 |
EPHA1 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0045785 | Not Cancer Driver | No | 147 | 0.151 | 211 | 38 | 0.18 | 0 |
EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0045785 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0045785 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0045785 | Census, Compendium | Yes | 275 | 0.219 | 314 | 41 | 0.131 | 1 |
ETS1_ENST00000319397 | ETS1 | P14921 | Protein C-ets-1 | chr11 | GO:0045785 | Not Cancer Driver | No | 68 | 0.154 | 78 | 9 | 0.115 | 0 |
F11R | F11R | Q9Y624 | Junctional adhesion molecule A | chr1 | GO:0045785 | Not Cancer Driver | No | 47 | 0.157 | 72 | 15 | 0.208 | 0 |
FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0045785 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
FAM49B_ENST00000519540 | CYRIB | Q9NUQ9 | CYFIP-related Rac1 interactor B | chr8 | GO:0045785 | Not Cancer Driver | No | 53 | 0.164 | 78 | 11 | 0.141 | 0 |
FERMT1 | FERMT1 | Q9BQL6 | Fermitin family homolog 1 | chr20 | GO:0045785 | Not Cancer Driver | No | 100 | 0.148 | 65 | 8 | 0.123 | 2 |
FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0045785 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0045785 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0045785 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0045785 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0045785 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0045785 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | GO:0045785 | Not Cancer Driver | No | 43 | 0.101 | 122 | 15 | 0.123 | 0 |
FLOT2 | FLOT2 | Q14254 | Flotillin-2 | chr17 | GO:0045785 | Not Cancer Driver | No | 56 | 0.131 | 20 | 3 | 0.15 | 0 |
FMN1 | FMN1 | Q68DA7 | Formin-1 | chr15 | GO:0045785 | Not Cancer Driver | No | 117 | 0.082 | 983 | 67 | 0.068 | 0 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0045785 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
FOXA1 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | GO:0045785 | Census, Compendium | Yes | 100 | 0.212 | 295 | 53 | 0.18 | 0 |
FOXA2_ENST00000377115 | FOXA2 | Q9Y261 | Hepatocyte nuclear factor 3-beta | chr20 | GO:0045785 | Compendium | Yes | 70 | 0.153 | 258 | 34 | 0.132 | 0 |
FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0045785 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0045785 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0045785 | Not Cancer Driver | No | 38 | 0.088 | 186 | 16 | 0.086 | 10 |
FRMD5 | FRMD5 | Q7Z6J6 | FERM domain-containing protein 5 | chr15 | GO:0045785 | Not Cancer Driver | No | 69 | 0.121 | 134 | 20 | 0.149 | 0 |
FUT1_ENST00000645652 | FUT1 | P19526 | Galactoside alpha-(1,2)-fucosyltransferase 1 | chr19 | GO:0045785 | Not Cancer Driver | No | 63 | 0.173 | 17 | 3 | 0.176 | 0 |
FUT4 | FUT4 | P22083 | Alpha-(1,3)-fucosyltransferase 4 | chr11 | GO:0045785 | Not Cancer Driver | No | 49 | 0.092 | 193 | 9 | 0.047 | 0 |
FUT7 | FUT7 | Q11130 | Alpha-(1,3)-fucosyltransferase 7 | chr9 | GO:0045785 | Not Cancer Driver | No | 28 | 0.082 | 25 | 3 | 0.12 | 0 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0045785 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
GCNT2_ENST00000379597 | GCNT2 | Q8N0V5 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase | chr6 | GO:0045785 | Not Cancer Driver | No | 40 | 0.1 | 3 | 0 | 0.0 | 0 |
GLI2_ENST00000361492 | GLI2 | P10070 | Zinc finger protein GLI2 | chr2 | GO:0045785 | Not Cancer Driver | No | 287 | 0.181 | 1403 | 244 | 0.174 | 2 |
GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0045785 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
GP6_ENST00000417454 | GP6 | Q9HCN6 | Platelet glycoprotein VI | chr19 | GO:0045785 | Not Cancer Driver | No | 57 | 0.168 | 122 | 21 | 0.172 | 2 |
GPAM | GPAM | Q9HCL2 | Glycerol-3-phosphate acyltransferase 1, mitochondrial | chr10 | GO:0045785 | Not Cancer Driver | No | 108 | 0.13 | 83 | 7 | 0.084 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0045785 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0045785 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
HHLA2_ENST00000489514 | HHLA2 | Q9UM44 | HERV-H LTR-associating protein 2 | chr3 | GO:0045785 | Not Cancer Driver | No | 85 | 0.205 | 57 | 10 | 0.175 | 0 |
HLA-A_ENST00000376809 | HLA-A | P04439 | HLA class I histocompatibility antigen, A alpha chain | chr6 | GO:0045785 | Census, Compendium | Yes | 128 | 0.351 | 125 | 60 | 0.48 | 0 |
HLA-DMB | HLA-DMB | P28068 | HLA class II histocompatibility antigen, DM beta chain | chr6 | GO:0045785 | Not Cancer Driver | No | 41 | 0.156 | 41 | 9 | 0.22 | 0 |
HLA-DRA | HLA-DRA | P01903 | HLA class II histocompatibility antigen, DR alpha chain | chr6 | GO:0045785 | Not Cancer Driver | No | 52 | 0.205 | 12 | 1 | 0.083 | 0 |
HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0045785 | Not Cancer Driver | No | 48 | 0.18 | 12 | 1 | 0.083 | 0 |
HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0045785 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0045785 | Not Cancer Driver | No | 94 | 0.278 | 85 | 22 | 0.259 | 0 |
HLX | HLX | Q14774 | H2.0-like homeobox protein | chr1 | GO:0045785 | Not Cancer Driver | No | 107 | 0.219 | 412 | 98 | 0.238 | 0 |
HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0045785 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
HRG | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0045785 | Not Cancer Driver | No | 121 | 0.23 | 277 | 75 | 0.271 | 2 |
HSPH1_ENST00000320027 | HSPH1 | Q92598 | Heat shock protein 105 kDa | chr13 | GO:0045785 | Not Cancer Driver | No | 103 | 0.12 | 323 | 42 | 0.13 | 0 |
HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0045785 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
IBSP | IBSP | P21815 | Bone sialoprotein 2 | chr4 | GO:0045785 | Not Cancer Driver | No | 79 | 0.249 | 274 | 69 | 0.252 | 0 |
ICOS | ICOS | Q9Y6W8 | Inducible T-cell costimulator | chr2 | GO:0045785 | Not Cancer Driver | No | 36 | 0.181 | 0 | 0 | 0.0 | 0 |
ICOSLG_ENST00000407780 | ICOSLG | O75144 | ICOS ligand | chr21 | GO:0045785 | Not Cancer Driver | No | 25 | 0.083 | 30 | 2 | 0.067 | 0 |
IFNG | IFNG | P01579 | Interferon gamma | chr12 | GO:0045785 | Not Cancer Driver | No | 51 | 0.307 | 23 | 6 | 0.261 | 0 |
IFT74_ENST00000433700 | IFT74 | Q96LB3 | Intraflagellar transport protein 74 homolog | chr9 | GO:0045785 | Not Cancer Driver | No | 47 | 0.078 | 490 | 38 | 0.078 | 0 |
IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0045785 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0045785 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
IGFBP2 | IGFBP2 | P18065 | Insulin-like growth factor-binding protein 2 | chr2 | GO:0045785 | Not Cancer Driver | No | 32 | 0.098 | 171 | 24 | 0.14 | 0 |
IHH | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0045785 | Not Cancer Driver | No | 58 | 0.141 | 111 | 15 | 0.135 | 6 |
IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0045785 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0045785 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
IL12RB1_ENST00000593993 | IL12RB1 | P42701 | Interleukin-12 receptor subunit beta-1 | chr19 | GO:0045785 | Not Cancer Driver | No | 108 | 0.163 | 207 | 38 | 0.184 | 1 |
IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0045785 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0045785 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0045785 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
IL2 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0045785 | Census | Yes | 24 | 0.157 | 6 | 1 | 0.167 | 0 |
IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0045785 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
IL23R | IL23R | Q5VWK5 | Interleukin-23 receptor | chr1 | GO:0045785 | Not Cancer Driver | No | 70 | 0.111 | 117 | 19 | 0.162 | 0 |
IL27RA | IL27RA | Q6UWB1 | Interleukin-27 receptor subunit alpha | chr19 | GO:0045785 | Not Cancer Driver | No | 91 | 0.143 | 167 | 23 | 0.138 | 0 |
IL2RA | IL2RA | P01589 | Interleukin-2 receptor subunit alpha | chr10 | GO:0045785 | Not Cancer Driver | No | 51 | 0.188 | 131 | 29 | 0.221 | 2 |
IL4I1_ENST00000391826 | IL4I1 | Q96RQ9 | L-amino-acid oxidase | chr19 | GO:0045785 | Not Cancer Driver | No | 65 | 0.115 | 136 | 14 | 0.103 | 0 |
IL4R_ENST00000543915 | IL4R | P24394 | Interleukin-4 receptor subunit alpha | chr16 | GO:0045785 | Not Cancer Driver | No | 133 | 0.161 | 420 | 64 | 0.152 | 0 |
IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0045785 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0045785 | Census, Compendium | Yes | 102 | 0.111 | 315 | 40 | 0.127 | 2 |
IL7R | IL7R | P16871 | Interleukin-7 receptor subunit alpha | chr5 | GO:0045785 | Census, Compendium | Yes | 177 | 0.386 | 88 | 48 | 0.545 | 1 |
ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0045785 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:0045785 | Compendium | Yes | 71 | 0.1 | 337 | 39 | 0.116 | 0 |
ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0045785 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | GO:0045785 | Not Cancer Driver | No | 254 | 0.246 | 97 | 27 | 0.278 | 0 |
ITGAV | ITGAV | P06756 | Integrin alpha-V | chr2 | GO:0045785 | Census | Yes | 153 | 0.146 | 92 | 9 | 0.098 | 0 |
ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0045785 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0045785 | Not Cancer Driver | No | 147 | 0.191 | 59 | 9 | 0.153 | 15 |
ITPKB_ENST00000272117 | ITPKB | P27987 | Inositol-trisphosphate 3-kinase B | chr1 | GO:0045785 | Not Cancer Driver | No | 148 | 0.156 | 719 | 119 | 0.166 | 0 |
JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | GO:0045785 | Census, Compendium | Yes | 147 | 0.127 | 120 | 7 | 0.058 | 2 |
JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0045785 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
JAK3 | JAK3 | P52333 | Tyrosine-protein kinase JAK3 | chr19 | GO:0045785 | Census, Compendium | Yes | 167 | 0.149 | 63 | 10 | 0.159 | 7 |
JUP | JUP | P14923 | Junction plakoglobin | chr17 | GO:0045785 | Not Cancer Driver | No | 112 | 0.15 | 241 | 37 | 0.154 | 0 |
KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0045785 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
KIFAP3 | KIFAP3 | Q92845 | Kinesin-associated protein 3 | chr1 | GO:0045785 | Not Cancer Driver | No | 116 | 0.146 | 71 | 10 | 0.141 | 0 |
KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0045785 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0045785 | Census | Yes | 86 | 0.169 | 94 | 13 | 0.138 | 1 |
LDB1 | LDB1 | Q86U70 | LIM domain-binding protein 1 | chr10 | GO:0045785 | Compendium | Yes | 56 | 0.136 | 177 | 29 | 0.164 | 0 |
LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0045785 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
LGALS1 | LGALS1 | P09382 | Galectin-1 | chr22 | GO:0045785 | Not Cancer Driver | No | 16 | 0.119 | 0 | 0 | 0.0 | 0 |
LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0045785 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0045785 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
LILRB1_ENST00000396331 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0045785 | Not Cancer Driver | No | 203 | 0.312 | 291 | 97 | 0.333 | 0 |
LILRB2_ENST00000314446 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0045785 | Not Cancer Driver | No | 148 | 0.248 | 235 | 50 | 0.213 | 0 |
LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0045785 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
LIMS1_ENST00000393310 | LIMS1 | P48059 | LIM and senescent cell antigen-like-containing domain protein 1 | chr2 | GO:0045785 | Not Cancer Driver | No | 34 | 0.105 | 0 | 0 | 0.0 | 0 |
LIMS2_ENST00000355119 | LIMS2 | Q7Z4I7 | LIM and senescent cell antigen-like-containing domain protein 2 | chr2 | GO:0045785 | Not Cancer Driver | No | 55 | 0.161 | 8 | 0 | 0.0 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0045785 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0045785 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
MAP3K8_ENST00000542547 | MAP3K8 | P41279 | Mitogen-activated protein kinase kinase kinase 8 | chr10 | GO:0045785 | Not Cancer Driver | No | 58 | 0.124 | 109 | 10 | 0.092 | 0 |
MAP4K4_ENST00000347699 | MAP4K4 | O95819 | Mitogen-activated protein kinase kinase kinase kinase 4 | chr2 | GO:0045785 | Not Cancer Driver | No | 143 | 0.115 | 649 | 55 | 0.085 | 0 |
MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0045785 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
MIP | MIP | P30301 | Lens fiber major intrinsic protein | chr12 | GO:0045785 | Not Cancer Driver | No | 71 | 0.27 | 20 | 1 | 0.05 | 6 |
MMRN1 | MMRN1 | Q13201 | Multimerin-1 | chr4 | GO:0045785 | Not Cancer Driver | No | 241 | 0.196 | 373 | 75 | 0.201 | 0 |
MYADM | MYADM | Q96S97 | Myeloid-associated differentiation marker | chr19 | GO:0045785 | Not Cancer Driver | No | 73 | 0.227 | 0 | 0 | 0.0 | 0 |
MYB_ENST00000367814 | MYB | P10242 | Transcriptional activator Myb | chr6 | GO:0045785 | Census | Yes | 82 | 0.128 | 528 | 69 | 0.131 | 0 |
MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0045785 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0045785 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:0045785 | Not Cancer Driver | No | 106 | 0.127 | 516 | 72 | 0.14 | 0 |
NFAT5_ENST00000354436 | NFAT5 | O94916 | Nuclear factor of activated T-cells 5 | chr16 | GO:0045785 | Not Cancer Driver | No | 142 | 0.093 | 1307 | 119 | 0.091 | 0 |
NFKBID | NFKBID | Q8NI38 | NF-kappa-B inhibitor delta | chr19 | GO:0045785 | Not Cancer Driver | No | 47 | 0.15 | 124 | 20 | 0.161 | 0 |
NFKBIZ | NFKBIZ | Q9BYH8 | NF-kappa-B inhibitor zeta | chr3 | GO:0045785 | Not Cancer Driver | No | 96 | 0.134 | 443 | 53 | 0.12 | 0 |
NKAP | NKAP | Q8N5F7 | NF-kappa-B-activating protein | chrX | GO:0045785 | Not Cancer Driver | No | 80 | 0.193 | 409 | 77 | 0.188 | 3 |
NLRP3_ENST00000391828 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0045785 | Not Cancer Driver | No | 339 | 0.327 | 64 | 33 | 0.516 | 37 |
NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0045785 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
NR4A3_ENST00000395097 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0045785 | Census | Yes | 83 | 0.133 | 298 | 37 | 0.124 | 0 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0045785 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
OLFM4 | OLFM4 | Q6UX06 | Olfactomedin-4 | chr13 | GO:0045785 | Not Cancer Driver | No | 117 | 0.229 | 54 | 11 | 0.204 | 0 |
P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | GO:0045785 | Not Cancer Driver | No | 57 | 0.167 | 21 | 2 | 0.095 | 3 |
P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | GO:0045785 | Not Cancer Driver | No | 61 | 0.12 | 79 | 15 | 0.19 | 1 |
PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0045785 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
PDCD1LG2 | PDCD1LG2 | Q9BQ51 | Programmed cell death 1 ligand 2 | chr9 | GO:0045785 | Census, Compendium | Yes | 33 | 0.121 | 41 | 13 | 0.317 | 0 |
PDPN_ENST00000621990 | PDPN | Q86YL7 | Podoplanin | chr1 | GO:0045785 | Not Cancer Driver | No | 37 | 0.228 | 96 | 24 | 0.25 | 0 |
PIEZO1 | PIEZO1 | Q92508 | Piezo-type mechanosensitive ion channel component 1 | chr16 | GO:0045785 | Not Cancer Driver | No | 122 | 0.048 | 471 | 26 | 0.055 | 12 |
PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0045785 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
PLAUR | PLAUR | Q03405 | Urokinase plasminogen activator surface receptor | chr19 | GO:0045785 | Not Cancer Driver | No | 49 | 0.146 | 18 | 5 | 0.278 | 0 |
PLEKHA2 | PLEKHA2 | Q9HB19 | Pleckstrin homology domain-containing family A member 2 | chr8 | GO:0045785 | Not Cancer Driver | No | 38 | 0.089 | 155 | 10 | 0.065 | 0 |
PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | GO:0045785 | Not Cancer Driver | No | 38 | 0.131 | 29 | 2 | 0.069 | 5 |
PODXL | PODXL | O00592 | Podocalyxin | chr7 | GO:0045785 | Not Cancer Driver | No | 69 | 0.124 | 432 | 56 | 0.13 | 0 |
POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | GO:0045785 | Not Cancer Driver | No | 36 | 0.098 | 94 | 13 | 0.138 | 0 |
PPM1F | PPM1F | P49593 | Protein phosphatase 1F | chr22 | GO:0045785 | Not Cancer Driver | No | 53 | 0.117 | 242 | 24 | 0.099 | 0 |
PPP3CA | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0045785 | Compendium | Yes | 85 | 0.163 | 140 | 27 | 0.193 | 7 |
PREX1 | PREX1 | Q8TCU6 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | chr20 | GO:0045785 | Not Cancer Driver | No | 297 | 0.179 | 307 | 55 | 0.179 | 0 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0045785 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
PRKCQ | PRKCQ | Q04759 | Protein kinase C theta type | chr10 | GO:0045785 | Not Cancer Driver | No | 147 | 0.208 | 28 | 9 | 0.321 | 0 |
PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | GO:0045785 | Not Cancer Driver | No | 70 | 0.118 | 116 | 11 | 0.095 | 0 |
PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0045785 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
PRSS2_ENST00000539842 | PRSS2 | P07478 | Trypsin-2 | chr7 | GO:0045785 | Not Cancer Driver | No | 51 | 0.206 | 9 | 1 | 0.111 | 0 |
PTAFR_ENST00000305392 | PTAFR | P25105 | Platelet-activating factor receptor | chr1 | GO:0045785 | Not Cancer Driver | No | 42 | 0.123 | 0 | 0 | 0.0 | 0 |
PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0045785 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0045785 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0045785 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
PTPN23 | PTPN23 | Q9H3S7 | Tyrosine-protein phosphatase non-receptor type 23 | chr3 | GO:0045785 | Not Cancer Driver | No | 147 | 0.09 | 796 | 71 | 0.089 | 2 |
PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0045785 | Census, Compendium | Yes | 73 | 0.123 | 192 | 25 | 0.13 | 0 |
PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0045785 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0045785 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
PTPRU | PTPRU | Q92729 | Receptor-type tyrosine-protein phosphatase U | chr1 | GO:0045785 | Not Cancer Driver | No | 248 | 0.172 | 325 | 64 | 0.197 | 0 |
PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0045785 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0045785 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | GO:0045785 | Not Cancer Driver | No | 24 | 0.125 | 0 | 0 | 0.0 | 4 |
RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0045785 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
RASAL3 | RASAL3 | Q86YV0 | RAS protein activator like-3 | chr19 | GO:0045785 | Not Cancer Driver | No | 114 | 0.113 | 536 | 68 | 0.127 | 0 |
RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0045785 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0045785 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0045785 | Census, Compendium | Yes | 208 | 0.187 | 105 | 12 | 0.114 | 139 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0045785 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | GO:0045785 | Not Cancer Driver | No | 20 | 0.095 | 10 | 0 | 0.0 | 0 |
RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0045785 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0045785 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0045785 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
RRAS | RRAS | P10301 | Ras-related protein R-Ras | chr19 | GO:0045785 | Not Cancer Driver | No | 25 | 0.115 | 71 | 6 | 0.085 | 0 |
RREB1_ENST00000349384 | RREB1 | Q92766 | Ras-responsive element-binding protein 1 | chr6 | GO:0045785 | Not Cancer Driver | No | 213 | 0.126 | 1152 | 144 | 0.125 | 0 |
RUNX1_ENST00000344691 | RUNX1 | Q01196 | Runt-related transcription factor 1 | chr21 | GO:0045785 | Census, Compendium | Yes | 81 | 0.179 | 360 | 58 | 0.161 | 2 |
RUNX3_ENST00000308873 | RUNX3 | Q13761 | Runt-related transcription factor 3 | chr1 | GO:0045785 | Not Cancer Driver | No | 59 | 0.142 | 331 | 45 | 0.136 | 0 |
S100A10 | S100A10 | P60903 | Protein S100-A10 | chr1 | GO:0045785 | Not Cancer Driver | No | 11 | 0.113 | 3 | 1 | 0.333 | 0 |
SAA1 | SAA1 | P0DJI8 | Serum amyloid A-1 protein | chr11 | GO:0045785 | Not Cancer Driver | No | 23 | 0.189 | 25 | 5 | 0.2 | 0 |
SART1 | SART1 | O43290 | U4/U6.U5 tri-snRNP-associated protein 1 | chr11 | GO:0045785 | Not Cancer Driver | No | 71 | 0.089 | 685 | 63 | 0.092 | 0 |
SASH3 | SASH3 | O75995 | SAM and SH3 domain-containing protein 3 | chrX | GO:0045785 | Not Cancer Driver | No | 59 | 0.155 | 327 | 49 | 0.15 | 0 |
SDC4 | SDC4 | P31431 | Syndecan-4 | chr20 | GO:0045785 | Census, Compendium | Yes | 34 | 0.172 | 110 | 25 | 0.227 | 0 |
SELE | SELE | P16581 | E-selectin | chr1 | GO:0045785 | Not Cancer Driver | No | 137 | 0.225 | 12 | 0 | 0.0 | 0 |
SELP | SELP | P16109 | P-selectin | chr1 | GO:0045785 | Not Cancer Driver | No | 226 | 0.272 | 14 | 2 | 0.143 | 0 |
SERPINF2_ENST00000382061 | SERPINF2 | P08697 | Alpha-2-antiplasmin | chr17 | GO:0045785 | Not Cancer Driver | No | 62 | 0.126 | 112 | 21 | 0.188 | 1 |
SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0045785 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0045785 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0045785 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
SKAP1_ENST00000584924 | SKAP1 | Q86WV1 | Src kinase-associated phosphoprotein 1 | chr17 | GO:0045785 | Not Cancer Driver | No | 67 | 0.187 | 130 | 27 | 0.208 | 0 |
SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0045785 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0045785 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | GO:0045785 | Census, Compendium | Yes | 22 | 0.104 | 66 | 3 | 0.045 | 2 |
SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0045785 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
SOX12 | SOX12 | O15370 | Transcription factor SOX-12 | chr20 | GO:0045785 | Not Cancer Driver | No | 20 | 0.063 | 307 | 19 | 0.062 | 0 |
SOX13 | SOX13 | Q9UN79 | Transcription factor SOX-13 | chr1 | GO:0045785 | Not Cancer Driver | No | 85 | 0.137 | 564 | 77 | 0.137 | 0 |
SOX4 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | GO:0045785 | Not Cancer Driver | No | 28 | 0.059 | 400 | 24 | 0.06 | 4 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0045785 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
ST3GAL4_ENST00000534083 | ST3GAL4 | Q11206 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 | chr11 | GO:0045785 | Not Cancer Driver | No | 31 | 0.093 | 3 | 2 | 0.667 | 0 |
STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0045785 | Census, Compendium | Yes | 93 | 0.118 | 144 | 19 | 0.132 | 5 |
STK4 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0045785 | Not Cancer Driver | No | 70 | 0.144 | 231 | 30 | 0.13 | 0 |
STX3 | STX3 | Q13277 | Syntaxin-3 | chr11 | GO:0045785 | Not Cancer Driver | No | 51 | 0.176 | 129 | 30 | 0.233 | 0 |
STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0045785 | Not Cancer Driver | No | 50 | 0.168 | 152 | 20 | 0.132 | 0 |
SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0045785 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0045785 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
TESK1_ENST00000336395 | TESK1 | Q15569 | Dual specificity testis-specific protein kinase 1 | chr9 | GO:0045785 | Not Cancer Driver | No | 63 | 0.101 | 339 | 35 | 0.103 | 0 |
TESPA1 | TESPA1 | A2RU30 | Protein TESPA1 | chr12 | GO:0045785 | Not Cancer Driver | No | 127 | 0.244 | 284 | 84 | 0.296 | 0 |
TFE3 | TFE3 | P19532 | Transcription factor E3 | chrX | GO:0045785 | Census | Yes | 92 | 0.16 | 524 | 84 | 0.16 | 0 |
TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0045785 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0045785 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | GO:0045785 | Not Cancer Driver | No | 123 | 0.179 | 107 | 26 | 0.243 | 0 |
THY1 | THY1 | P04216 | Thy-1 membrane glycoprotein | chr11 | GO:0045785 | Not Cancer Driver | No | 24 | 0.149 | 5 | 0 | 0.0 | 0 |
TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | GO:0045785 | Not Cancer Driver | No | 198 | 0.113 | 1350 | 151 | 0.112 | 0 |
TMEM102 | TMEM102 | Q8N9M5 | Transmembrane protein 102 | chr17 | GO:0045785 | Not Cancer Driver | No | 38 | 0.075 | 141 | 13 | 0.092 | 0 |
TMIGD2 | TMIGD2 | Q96BF3 | Transmembrane and immunoglobulin domain-containing protein 2 | chr19 | GO:0045785 | Not Cancer Driver | No | 57 | 0.202 | 120 | 32 | 0.267 | 0 |
TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0045785 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
TNFRSF13C | TNFRSF13C | Q96RJ3 | Tumor necrosis factor receptor superfamily member 13C | chr22 | GO:0045785 | Not Cancer Driver | No | 17 | 0.092 | 128 | 15 | 0.117 | 0 |
TNFRSF14 | TNFRSF14 | Q92956 | Tumor necrosis factor receptor superfamily member 14 | chr1 | GO:0045785 | Census, Compendium | Yes | 33 | 0.117 | 54 | 8 | 0.148 | 0 |
TNFRSF18_ENST00000379268 | TNFRSF18 | Q9Y5U5 | Tumor necrosis factor receptor superfamily member 18 | chr1 | GO:0045785 | Not Cancer Driver | No | 22 | 0.091 | 23 | 1 | 0.043 | 0 |
TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0045785 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
TNFSF13B | TNFSF13B | Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | chr13 | GO:0045785 | Not Cancer Driver | No | 41 | 0.144 | 91 | 15 | 0.165 | 0 |
TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0045785 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
TNFSF4 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0045785 | Not Cancer Driver | No | 28 | 0.153 | 1 | 0 | 0.0 | 0 |
TNFSF9 | TNFSF9 | P41273 | Tumor necrosis factor ligand superfamily member 9 | chr19 | GO:0045785 | Not Cancer Driver | No | 32 | 0.126 | 39 | 4 | 0.103 | 0 |
TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | GO:0045785 | Not Cancer Driver | No | 33 | 0.116 | 234 | 29 | 0.124 | 8 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0045785 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
TRIOBP_ENST00000644935 | TRIOBP | Q9H2D6 | TRIO and F-actin-binding protein | chr22 | GO:0045785 | Not Cancer Driver | No | 386 | 0.163 | 2196 | 370 | 0.168 | 1 |
TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0045785 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
TSTA3_ENST00000529064 | GFUS | Q13630 | GDP-L-fucose synthase | chr8 | GO:0045785 | Not Cancer Driver | No | 38 | 0.118 | 19 | 2 | 0.105 | 0 |
TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | GO:0045785 | Not Cancer Driver | No | 148 | 0.125 | 213 | 29 | 0.136 | 0 |
UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0045785 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
UTRN | UTRN | P46939 | Utrophin | chr6 | GO:0045785 | Not Cancer Driver | No | 476 | 0.139 | 1283 | 183 | 0.143 | 0 |
VAV1 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0045785 | Census, Compendium | Yes | 165 | 0.195 | 113 | 19 | 0.168 | 0 |
VAV3 | VAV3 | Q9UKW4 | Guanine nucleotide exchange factor VAV3 | chr1 | GO:0045785 | Not Cancer Driver | No | 153 | 0.181 | 102 | 18 | 0.176 | 0 |
VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0045785 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
VNN1 | VNN1 | O95497 | Pantetheinase | chr6 | GO:0045785 | Not Cancer Driver | No | 88 | 0.172 | 20 | 5 | 0.25 | 0 |
VSIR | VSIR | Q9H7M9 | V-type immunoglobulin domain-containing suppressor of T-cell activation | chr10 | GO:0045785 | Not Cancer Driver | No | 52 | 0.167 | 135 | 19 | 0.141 | 0 |
WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0045785 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0045785 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0045785 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0045785 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0045785 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |
ZAP70 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0045785 | Not Cancer Driver | No | 126 | 0.204 | 117 | 17 | 0.145 | 8 |
ZBTB1 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | GO:0045785 | Not Cancer Driver | No | 70 | 0.098 | 271 | 27 | 0.1 | 0 |
ZBTB16_ENST00000392996 | ZBTB16 | Q05516 | Zinc finger and BTB domain-containing protein 16 | chr11 | GO:0045785 | Census, Compendium | Yes | 131 | 0.195 | 268 | 50 | 0.187 | 1 |
ZBTB7B_ENST00000368426 | ZBTB7B | O15156 | Zinc finger and BTB domain-containing protein 7B | chr1 | GO:0045785 | Compendium | Yes | 103 | 0.191 | 353 | 70 | 0.198 | 0 |
ZFHX3_ENST00000268489 | ZFHX3 | Q15911 | Zinc finger homeobox protein 3 | chr16 | GO:0045785 | Census, Compendium | Yes | 501 | 0.135 | 2555 | 337 | 0.132 | 0 |