Total number of protein in "GO:0045766" GO term: 156
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0045766 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0045766 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
ADAM12 | ADAM12 | O43184 | Disintegrin and metalloproteinase domain-containing protein 12 | chr10 | GO:0045766 | Not Cancer Driver | No | 165 | 0.182 | 205 | 37 | 0.18 | 0 |
ADM | ADM | P35318 | Pro-adrenomedullin | chr11 | GO:0045766 | Not Cancer Driver | No | 20 | 0.108 | 113 | 13 | 0.115 | 0 |
ADM2_ENST00000395737 | ADM2 | Q7Z4H4 | Protein ADM2 | chr22 | GO:0045766 | Not Cancer Driver | No | 14 | 0.095 | 113 | 11 | 0.097 | 0 |
AGGF1 | AGGF1 | Q8N302 | Angiogenic factor with G patch and FHA domains 1 | chr5 | GO:0045766 | Not Cancer Driver | No | 100 | 0.14 | 582 | 80 | 0.137 | 1 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | GO:0045766 | Not Cancer Driver | No | 126 | 0.147 | 141 | 15 | 0.106 | 11 |
AKT3_ENST00000366539 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | GO:0045766 | Census, Compendium | Yes | 92 | 0.192 | 131 | 24 | 0.183 | 3 |
ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0045766 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
ANGPT4 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0045766 | Not Cancer Driver | No | 104 | 0.207 | 150 | 32 | 0.213 | 0 |
ANGPTL3 | ANGPTL3 | Q9Y5C1 | Angiopoietin-related protein 3 | chr1 | GO:0045766 | Not Cancer Driver | No | 52 | 0.113 | 154 | 26 | 0.169 | 0 |
ANGPTL4 | ANGPTL4 | Q9BY76 | Angiopoietin-related protein 4 | chr19 | GO:0045766 | Not Cancer Driver | No | 47 | 0.116 | 180 | 22 | 0.122 | 0 |
ANXA3 | ANXA3 | P12429 | Annexin A3 | chr4 | GO:0045766 | Not Cancer Driver | No | 53 | 0.164 | 22 | 4 | 0.182 | 0 |
APELA | APELA | P0DMC3 | Apelin receptor early endogenous ligand | chr4 | GO:0045766 | Not Cancer Driver | No | 1 | 0.019 | 0 | 0 | 0.0 | 0 |
APLNR | APLNR | P35414 | Apelin receptor | chr11 | GO:0045766 | Not Cancer Driver | No | 96 | 0.253 | 29 | 8 | 0.276 | 0 |
AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0045766 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
BMPER | BMPER | Q8N8U9 | BMP-binding endothelial regulator protein | chr7 | GO:0045766 | Not Cancer Driver | No | 196 | 0.286 | 0 | 0 | 0.0 | 1 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0045766 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
BTG1 | BTG1 | P62324 | Protein BTG1 | chr12 | GO:0045766 | Census, Compendium | Yes | 21 | 0.123 | 19 | 0 | 0.0 | 0 |
C3 | C3 | P01024 | Complement C3 | chr19 | GO:0045766 | Not Cancer Driver | No | 337 | 0.203 | 287 | 50 | 0.174 | 12 |
C3AR1 | C3AR1 | Q16581 | C3a anaphylatoxin chemotactic receptor | chr12 | GO:0045766 | Not Cancer Driver | No | 88 | 0.183 | 72 | 16 | 0.222 | 0 |
C5 | C5 | P01031 | Complement C5 | chr9 | GO:0045766 | Not Cancer Driver | No | 192 | 0.115 | 84 | 9 | 0.107 | 0 |
C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0045766 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0045766 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
CCBE1 | CCBE1 | Q6UXH8 | Collagen and calcium-binding EGF domain-containing protein 1 | chr18 | GO:0045766 | Not Cancer Driver | No | 92 | 0.227 | 227 | 58 | 0.256 | 5 |
CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0045766 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
CCL24_ENST00000222902 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0045766 | Not Cancer Driver | No | 25 | 0.21 | 23 | 3 | 0.13 | 0 |
CCR3_ENST00000357422 | CCR3 | P51677 | C-C chemokine receptor type 3 | chr3 | GO:0045766 | Not Cancer Driver | No | 84 | 0.237 | 0 | 0 | 0.0 | 0 |
CD34 | CD34 | P28906 | Hematopoietic progenitor cell antigen CD34 | chr1 | GO:0045766 | Not Cancer Driver | No | 65 | 0.169 | 221 | 34 | 0.154 | 0 |
CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0045766 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0045766 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
CELA1 | CELA1 | Q9UNI1 | Chymotrypsin-like elastase family member 1 | chr12 | GO:0045766 | Not Cancer Driver | No | 48 | 0.186 | 20 | 0 | 0.0 | 0 |
CHI3L1 | CHI3L1 | P36222 | Chitinase-3-like protein 1 | chr1 | GO:0045766 | Not Cancer Driver | No | 66 | 0.172 | 24 | 5 | 0.208 | 0 |
CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0045766 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
CMA1 | CMA1 | P23946 | Chymase | chr14 | GO:0045766 | Not Cancer Driver | No | 47 | 0.19 | 9 | 1 | 0.111 | 0 |
CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0045766 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0045766 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
CXCL8 | CXCL8 | P10145 | Interleukin-8 | chr4 | GO:0045766 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0045766 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
CYBB | CYBB | P04839 | Cytochrome b-245 heavy chain | chrX | GO:0045766 | Not Cancer Driver | No | 109 | 0.191 | 11 | 3 | 0.273 | 65 |
CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0045766 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
CYSLTR1 | CYSLTR1 | Q9Y271 | Cysteinyl leukotriene receptor 1 | chrX | GO:0045766 | Not Cancer Driver | No | 58 | 0.172 | 8 | 1 | 0.125 | 0 |
DDAH1 | DDAH1 | O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | chr1 | GO:0045766 | Not Cancer Driver | No | 28 | 0.098 | 44 | 3 | 0.068 | 0 |
DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0045766 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
ECM1_ENST00000369047 | ECM1 | Q16610 | Extracellular matrix protein 1 | chr1 | GO:0045766 | Not Cancer Driver | No | 91 | 0.169 | 219 | 28 | 0.128 | 1 |
EMC10 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | GO:0045766 | Not Cancer Driver | No | 25 | 0.095 | 109 | 15 | 0.138 | 0 |
EMILIN2 | EMILIN2 | Q9BXX0 | EMILIN-2 | chr18 | GO:0045766 | Not Cancer Driver | No | 158 | 0.15 | 617 | 94 | 0.152 | 0 |
ENG | ENG | P17813 | Endoglin | chr9 | GO:0045766 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
EPHA1 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0045766 | Not Cancer Driver | No | 147 | 0.151 | 211 | 38 | 0.18 | 0 |
ERAP1_ENST00000443439 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | GO:0045766 | Not Cancer Driver | No | 78 | 0.083 | 70 | 2 | 0.029 | 0 |
ETS1_ENST00000319397 | ETS1 | P14921 | Protein C-ets-1 | chr11 | GO:0045766 | Not Cancer Driver | No | 68 | 0.154 | 78 | 9 | 0.115 | 0 |
F3 | F3 | P13726 | Tissue factor | chr1 | GO:0045766 | Not Cancer Driver | No | 28 | 0.095 | 61 | 7 | 0.115 | 0 |
FGF18 | FGF18 | O76093 | Fibroblast growth factor 18 | chr5 | GO:0045766 | Not Cancer Driver | No | 40 | 0.193 | 57 | 14 | 0.246 | 0 |
FGF1_ENST00000612258 | FGF1 | P05230 | Fibroblast growth factor 1 | chr5 | GO:0045766 | Not Cancer Driver | No | 30 | 0.194 | 29 | 2 | 0.069 | 0 |
FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0045766 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
FLT1 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | GO:0045766 | Not Cancer Driver | No | 299 | 0.223 | 103 | 20 | 0.194 | 0 |
FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0045766 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
FUT1_ENST00000645652 | FUT1 | P19526 | Galactoside alpha-(1,2)-fucosyltransferase 1 | chr19 | GO:0045766 | Not Cancer Driver | No | 63 | 0.173 | 17 | 3 | 0.176 | 0 |
GAB1_ENST00000262994 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0045766 | Not Cancer Driver | No | 79 | 0.114 | 570 | 68 | 0.119 | 1 |
GATA2_ENST00000487848 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0045766 | Census, Compendium | Yes | 72 | 0.15 | 370 | 49 | 0.132 | 6 |
GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0045766 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0045766 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0045766 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0045766 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0045766 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
GRN | GRN | P28799 | Progranulin | chr17 | GO:0045766 | Not Cancer Driver | No | 76 | 0.128 | 29 | 6 | 0.207 | 1 |
HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0045766 | Compendium | Yes | 233 | 0.32 | 43 | 16 | 0.372 | 0 |
HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0045766 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
HIPK1_ENST00000426820 | HIPK1 | Q86Z02 | Homeodomain-interacting protein kinase 1 | chr1 | GO:0045766 | Not Cancer Driver | No | 158 | 0.131 | 565 | 89 | 0.158 | 0 |
HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0045766 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0045766 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0045766 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0045766 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0045766 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
HSPB6 | HSPB6 | O14558 | Heat shock protein beta-6 | chr19 | GO:0045766 | Not Cancer Driver | No | 5 | 0.031 | 56 | 0 | 0.0 | 0 |
HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0045766 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0045766 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0045766 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0045766 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
ISL1 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0045766 | Not Cancer Driver | No | 85 | 0.244 | 180 | 41 | 0.228 | 0 |
ITGA5 | ITGA5 | P08648 | Integrin alpha-5 | chr12 | GO:0045766 | Not Cancer Driver | No | 127 | 0.121 | 201 | 29 | 0.144 | 0 |
ITGAX_ENST00000268296 | ITGAX | P20702 | Integrin alpha-X | chr16 | GO:0045766 | Not Cancer Driver | No | 245 | 0.211 | 82 | 15 | 0.183 | 0 |
ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0045766 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
ITGB8 | ITGB8 | P26012 | Integrin beta-8 | chr7 | GO:0045766 | Not Cancer Driver | No | 126 | 0.164 | 26 | 3 | 0.115 | 0 |
JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | GO:0045766 | Census, Compendium | Yes | 147 | 0.127 | 120 | 7 | 0.058 | 2 |
JCAD | JCAD | Q9P266 | Junctional protein associated with coronary artery disease | chr10 | GO:0045766 | Not Cancer Driver | No | 291 | 0.214 | 1337 | 290 | 0.217 | 0 |
JMJD8_ENST00000609261 | JMJD8 | Q96S16 | JmjC domain-containing protein 8 | chr16 | GO:0045766 | Not Cancer Driver | No | 11 | 0.042 | 22 | 0 | 0.0 | 0 |
JUP | JUP | P14923 | Junction plakoglobin | chr17 | GO:0045766 | Not Cancer Driver | No | 112 | 0.15 | 241 | 37 | 0.154 | 0 |
KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0045766 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
LRG1 | LRG1 | P02750 | Leucine-rich alpha-2-glycoprotein | chr19 | GO:0045766 | Not Cancer Driver | No | 63 | 0.182 | 29 | 8 | 0.276 | 0 |
MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0045766 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
MTDH | MTDH | Q86UE4 | Protein LYRIC | chr8 | GO:0045766 | Not Cancer Driver | No | 83 | 0.143 | 516 | 81 | 0.157 | 0 |
MYDGF | MYDGF | Q969H8 | Myeloid-derived growth factor | chr19 | GO:0045766 | Not Cancer Driver | No | 23 | 0.133 | 26 | 4 | 0.154 | 0 |
NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0045766 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
NINJ1 | NINJ1 | Q92982 | Ninjurin-1 | chr9 | GO:0045766 | Not Cancer Driver | No | 17 | 0.112 | 29 | 0 | 0.0 | 0 |
NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0045766 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0045766 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
NR2E1_ENST00000368986 | NR2E1 | Q9Y466 | Nuclear receptor subfamily 2 group E member 1 | chr6 | GO:0045766 | Not Cancer Driver | No | 75 | 0.195 | 57 | 6 | 0.105 | 0 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0045766 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
PAK4 | PAK4 | O96013 | Serine/threonine-protein kinase PAK 4 | chr19 | GO:0045766 | Not Cancer Driver | No | 58 | 0.098 | 340 | 33 | 0.097 | 0 |
PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0045766 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
PDCL3 | PDCL3 | Q9H2J4 | Phosducin-like protein 3 | chr2 | GO:0045766 | Not Cancer Driver | No | 48 | 0.201 | 73 | 13 | 0.178 | 0 |
PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0045766 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
PGF_ENST00000405431 | PGF | P49763 | Placenta growth factor | chr14 | GO:0045766 | Not Cancer Driver | No | 30 | 0.136 | 72 | 10 | 0.139 | 0 |
PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0045766 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
PIK3R6_ENST00000614407 | PIK3R6 | Q5UE93 | Phosphoinositide 3-kinase regulatory subunit 6 | chr17 | GO:0045766 | Not Cancer Driver | No | 100 | 0.133 | 156 | 26 | 0.167 | 0 |
PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | GO:0045766 | Not Cancer Driver | No | 78 | 0.147 | 58 | 13 | 0.224 | 0 |
PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0045766 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0045766 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | GO:0045766 | Census, Compendium | Yes | 205 | 0.306 | 148 | 40 | 0.27 | 0 |
PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0045766 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0045766 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0045766 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0045766 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
RAMP2 | RAMP2 | O60895 | Receptor activity-modifying protein 2 | chr17 | GO:0045766 | Not Cancer Driver | No | 18 | 0.103 | 34 | 6 | 0.176 | 0 |
RAPGEF3 | RAPGEF3 | O95398 | Rap guanine nucleotide exchange factor 3 | chr12 | GO:0045766 | Not Cancer Driver | No | 97 | 0.105 | 197 | 19 | 0.096 | 0 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | GO:0045766 | Not Cancer Driver | No | 52 | 0.265 | 19 | 2 | 0.105 | 0 |
RLN2 | RLN2 | P04090 | Prorelaxin H2 | chr9 | GO:0045766 | Not Cancer Driver | No | 31 | 0.168 | 39 | 4 | 0.103 | 0 |
RRAS | RRAS | P10301 | Ras-related protein R-Ras | chr19 | GO:0045766 | Not Cancer Driver | No | 25 | 0.115 | 71 | 6 | 0.085 | 0 |
RUNX1_ENST00000344691 | RUNX1 | Q01196 | Runt-related transcription factor 1 | chr21 | GO:0045766 | Census, Compendium | Yes | 81 | 0.179 | 360 | 58 | 0.161 | 2 |
S100A1 | S100A1 | P23297 | Protein S100-A1 | chr1 | GO:0045766 | Not Cancer Driver | No | 13 | 0.138 | 9 | 0 | 0.0 | 0 |
SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:0045766 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0045766 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
SERPINE1 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0045766 | Not Cancer Driver | No | 78 | 0.194 | 7 | 2 | 0.286 | 0 |
SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0045766 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0045766 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0045766 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
SLC39A12 | SLC39A12 | Q504Y0 | Zinc transporter ZIP12 | chr10 | GO:0045766 | Not Cancer Driver | No | 210 | 0.304 | 89 | 29 | 0.326 | 0 |
SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0045766 | Not Cancer Driver | No | 54 | 0.116 | 161 | 22 | 0.137 | 0 |
SMOC2_ENST00000356284 | SMOC2 | Q9H3U7 | SPARC-related modular calcium-binding protein 2 | chr6 | GO:0045766 | Not Cancer Driver | No | 82 | 0.184 | 216 | 52 | 0.241 | 0 |
SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0045766 | Not Cancer Driver | No | 96 | 0.122 | 599 | 71 | 0.119 | 0 |
SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0045766 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0045766 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | GO:0045766 | Not Cancer Driver | No | 70 | 0.102 | 387 | 45 | 0.116 | 13 |
TBXA2R_ENST00000375190 | TBXA2R | P21731 | Thromboxane A2 receptor | chr19 | GO:0045766 | Not Cancer Driver | No | 47 | 0.137 | 17 | 4 | 0.235 | 1 |
TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0045766 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0045766 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0045766 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0045766 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
TIE1 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0045766 | Not Cancer Driver | No | 200 | 0.176 | 223 | 46 | 0.206 | 0 |
TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | GO:0045766 | Not Cancer Driver | No | 198 | 0.113 | 1350 | 151 | 0.112 | 0 |
TLR3 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0045766 | Not Cancer Driver | No | 123 | 0.136 | 0 | 0 | 0.0 | 1 |
TMIGD2 | TMIGD2 | Q96BF3 | Transmembrane and immunoglobulin domain-containing protein 2 | chr19 | GO:0045766 | Not Cancer Driver | No | 57 | 0.202 | 120 | 32 | 0.267 | 0 |
TNFSF12 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:0045766 | Not Cancer Driver | No | 28 | 0.112 | 109 | 8 | 0.073 | 0 |
TNN | TNN | Q9UQP3 | Tenascin-N | chr1 | GO:0045766 | Not Cancer Driver | No | 426 | 0.328 | 637 | 231 | 0.363 | 0 |
TWIST1 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0045766 | Not Cancer Driver | No | 23 | 0.114 | 132 | 11 | 0.083 | 7 |
VASH2 | VASH2 | Q86V25 | Tubulinyl-Tyr carboxypeptidase 2 | chr1 | GO:0045766 | Not Cancer Driver | No | 32 | 0.09 | 106 | 9 | 0.085 | 0 |
VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0045766 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
VEGFB | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0045766 | Not Cancer Driver | No | 25 | 0.121 | 125 | 22 | 0.176 | 0 |
VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0045766 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
VEGFD | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0045766 | Not Cancer Driver | No | 59 | 0.167 | 33 | 6 | 0.182 | 0 |
WARS2 | WARS2 | Q9UGM6 | Tryptophan--tRNA ligase, mitochondrial | chr1 | GO:0045766 | Not Cancer Driver | No | 67 | 0.186 | 31 | 4 | 0.129 | 5 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0045766 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0045766 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0045766 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
ZNF304_ENST00000391705 | ZNF304 | Q9HCX3 | Zinc finger protein 304 | chr19 | GO:0045766 | Not Cancer Driver | No | 126 | 0.191 | 54 | 12 | 0.222 | 0 |