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Total number of protein in "GO:0045732" GO term:  116

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0045732 Not Cancer Driver No 240 0.099 497 44 0.089 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0045732 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0045732 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0045732 Not Cancer Driver No 67 0.144 161 10 0.062 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0045732 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0045732 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0045732 Not Cancer Driver No 25 0.079 124 6 0.048 12
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0045732 Not Cancer Driver No 104 0.126 92 10 0.109 0
ASB11 ASB11 Q8WXH4 Ankyrin repeat and SOCS box protein 11 chrX GO:0045732 Not Cancer Driver No 53 0.164 7 2 0.286 0
ASB5 ASB5 Q8WWX0 Ankyrin repeat and SOCS box protein 5 chr4 GO:0045732 Not Cancer Driver No 111 0.337 7 5 0.714 0
ASB9 ASB9 Q96DX5 Ankyrin repeat and SOCS box protein 9 chrX GO:0045732 Not Cancer Driver No 55 0.187 71 20 0.282 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0045732 Compendium Yes 77 0.11 53 8 0.151 6
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0045732 Not Cancer Driver No 46 0.127 181 24 0.133 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0045732 Census, Compendium Yes 120 0.139 619 88 0.142 4
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0045732 Not Cancer Driver No 98 0.087 861 79 0.092 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0045732 Census Yes 96 0.124 384 49 0.128 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0045732 Not Cancer Driver No 37 0.15 104 14 0.135 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0045732 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0045732 Not Cancer Driver No 40 0.159 0 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0045732 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0045732 Census Yes 160 0.163 562 104 0.185 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0045732 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0045732 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0045732 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0045732 Census, Compendium Yes 19 0.096 198 19 0.096 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0045732 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A3 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 GO:0045732 Not Cancer Driver No 66 0.169 75 10 0.133 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0045732 Not Cancer Driver No 138 0.151 207 38 0.184 2
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0045732 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0045732 Not Cancer Driver No 163 0.195 598 127 0.212 1
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0045732 Not Cancer Driver No 126 0.111 50 8 0.16 4
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 GO:0045732 Not Cancer Driver No 73 0.1 331 49 0.148 0
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 GO:0045732 Not Cancer Driver No 52 0.128 201 17 0.085 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0045732 Not Cancer Driver No 68 0.114 120 4 0.033 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0045732 Census, Compendium Yes 81 0.124 584 75 0.128 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0045732 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0045732 Not Cancer Driver No 74 0.149 184 30 0.163 0
GGA1 GGA1 Q9UJY5 ADP-ribosylation factor-binding protein GGA1 chr22 GO:0045732 Not Cancer Driver No 75 0.117 385 33 0.086 0
GGA3 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 GO:0045732 Not Cancer Driver No 73 0.101 419 41 0.098 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0045732 Census Yes 89 0.153 86 11 0.128 1
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0045732 Not Cancer Driver No 153 0.182 36 9 0.25 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0045732 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0045732 Not Cancer Driver No 56 0.133 146 13 0.089 0
HACE1 HACE1 Q8IYU2 E3 ubiquitin-protein ligase HACE1 chr6 GO:0045732 Not Cancer Driver No 126 0.139 103 12 0.117 0
HECW1 HECW1 Q76N89 E3 ubiquitin-protein ligase HECW1 chr7 GO:0045732 Not Cancer Driver No 420 0.262 748 191 0.255 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 GO:0045732 Not Cancer Driver No 348 0.221 845 195 0.231 4
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0045732 Census Yes 38 0.097 248 17 0.069 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0045732 Not Cancer Driver No 669 0.153 2091 329 0.157 21
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0045732 Not Cancer Driver No 90 0.088 96 8 0.083 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045732 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0045732 Not Cancer Driver No 39 0.145 16 3 0.188 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0045732 Not Cancer Driver No 95 0.105 335 42 0.125 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0045732 Not Cancer Driver No 119 0.138 63 3 0.048 104
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 GO:0045732 Not Cancer Driver No 85 0.159 66 11 0.167 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0045732 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0045732 Not Cancer Driver No 998 0.214 209 40 0.191 1
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0045732 Not Cancer Driver No 59 0.139 90 8 0.089 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0045732 Not Cancer Driver No 33 0.134 23 5 0.217 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0045732 Not Cancer Driver No 45 0.108 145 16 0.11 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0045732 Not Cancer Driver No 56 0.126 11 2 0.182 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0045732 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0045732 Not Cancer Driver No 29 0.201 24 4 0.167 1
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0045732 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0045732 Not Cancer Driver No 126 0.129 463 60 0.13 4
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0045732 Census, Compendium Yes 228 0.377 402 62 0.154 4
NKD1 NKD1 Q969G9 Protein naked cuticle homolog 1 chr16 GO:0045732 Not Cancer Driver No 72 0.153 436 67 0.154 0
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0045732 Not Cancer Driver No 162 0.141 253 34 0.134 0
NSF NSF P46459 Vesicle-fusing ATPase chr17 GO:0045732 Not Cancer Driver No 47 0.063 84 3 0.036 2
OAZ1 OAZ1 P54368 Ornithine decarboxylase antizyme 1 chr19 GO:0045732 Not Cancer Driver No 30 0.132 109 12 0.11 0
OAZ2 OAZ2 O95190 Ornithine decarboxylase antizyme 2 chr15 GO:0045732 Not Cancer Driver No 15 0.079 11 0 0.0 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 GO:0045732 Not Cancer Driver No 37 0.157 33 2 0.061 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0045732 Not Cancer Driver No 52 0.123 290 31 0.107 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0045732 Not Cancer Driver No 86 0.124 148 27 0.182 9
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0045732 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0045732 Not Cancer Driver No 75 0.116 202 15 0.074 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0045732 Not Cancer Driver No 110 0.237 78 15 0.192 31
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0045732 Not Cancer Driver No 27 0.13 11 0 0.0 4
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0045732 Not Cancer Driver No 63 0.14 105 13 0.124 0
RHBDD3 RHBDD3 Q9Y3P4 Rhomboid domain-containing protein 3 chr22 GO:0045732 Not Cancer Driver No 24 0.062 147 16 0.109 0
RILP RILP Q96NA2 Rab-interacting lysosomal protein chr17 GO:0045732 Not Cancer Driver No 30 0.075 333 21 0.063 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0045732 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0045732 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0045732 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0045732 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0045732 Not Cancer Driver No 37 0.083 129 10 0.078 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0045732 Not Cancer Driver No 83 0.111 77 9 0.117 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0045732 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0045732 Not Cancer Driver No 86 0.109 526 52 0.099 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045732 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0045732 Not Cancer Driver No 33 0.093 164 12 0.073 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0045732 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0045732 Not Cancer Driver No 87 0.116 242 28 0.116 0
SNF8 SNF8 Q96H20 Vacuolar-sorting protein SNF8 chr17 GO:0045732 Not Cancer Driver No 30 0.116 10 2 0.2 0
SNX1_ENST00000559844 SNX1 Q13596 Sorting nexin-1 chr15 GO:0045732 Not Cancer Driver No 61 0.117 214 25 0.117 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0045732 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0045732 Not Cancer Driver No 71 0.119 231 23 0.1 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0045732 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0045732 Compendium Yes 81 0.196 378 59 0.156 2
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0045732 Compendium Yes 86 0.169 495 82 0.166 18
STX5 STX5 Q13190 Syntaxin-5 chr11 GO:0045732 Not Cancer Driver No 36 0.101 147 14 0.095 0
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0045732 Not Cancer Driver No 65 0.099 200 20 0.1 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0045732 Not Cancer Driver No 40 0.065 188 9 0.048 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045732 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0045732 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0045732 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF12 TNFSF12 O43508 Tumor necrosis factor ligand superfamily member 12 chr17 GO:0045732 Not Cancer Driver No 28 0.112 109 8 0.073 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0045732 Not Cancer Driver No 82 0.126 87 10 0.115 3
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0045732 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0045732 Not Cancer Driver No 82 0.131 581 79 0.136 8
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0045732 Not Cancer Driver No 121 0.14 224 42 0.188 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0045732 Not Cancer Driver No 88 0.109 186 16 0.086 16
VIP VIP P01282 VIP peptides chr6 GO:0045732 Not Cancer Driver No 58 0.341 77 25 0.325 0
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 GO:0045732 Not Cancer Driver No 28 0.127 31 5 0.161 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0045732 Not Cancer Driver No 66 0.174 0 0 0.0 2
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 GO:0045732 Not Cancer Driver No 139 0.151 431 75 0.174 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0045732 Not Cancer Driver No 112 0.129 422 57 0.135 0