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Total number of protein in "GO:0045727" GO term:  119

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0045727 Not Cancer Driver No 126 0.147 141 15 0.106 11
BARHL2 BARHL2 Q9NY43 BarH-like 2 homeobox protein chr1 GO:0045727 Not Cancer Driver No 72 0.186 345 65 0.188 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0045727 Census Yes 44 0.097 259 23 0.089 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0045727 Not Cancer Driver No 14 0.05 103 6 0.058 2
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0045727 Census Yes 42 0.191 18 10 0.556 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0045727 Not Cancer Driver No 73 0.121 95 12 0.126 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 GO:0045727 Not Cancer Driver No 19 0.11 129 13 0.101 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0045727 Census Yes 11 0.062 19 0 0.0 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:0045727 Not Cancer Driver No 4 0.038 57 3 0.053 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0045727 Census, Compendium Yes 66 0.095 414 28 0.068 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0045727 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTIF_ENST00000256413 CTIF O43310 CBP80/20-dependent translation initiation factor chr18 GO:0045727 Not Cancer Driver No 97 0.162 384 62 0.161 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0045727 Not Cancer Driver No 61 0.112 31 3 0.097 40
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0045727 Census, Compendium Yes 133 0.201 301 47 0.156 18
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0045727 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0045727 Compendium Yes 182 0.143 331 42 0.127 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0045727 Not Cancer Driver No 60 0.119 131 17 0.13 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 GO:0045727 Not Cancer Driver No 111 0.129 78 14 0.179 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0045727 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:0045727 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:0045727 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF3C EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 GO:0045727 Not Cancer Driver No 15 0.016 391 12 0.031 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 GO:0045727 Not Cancer Driver No 63 0.115 200 26 0.13 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 GO:0045727 Census, Compendium Yes 73 0.164 27 1 0.037 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0045727 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0045727 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0045727 Not Cancer Driver No 104 0.115 382 43 0.113 0
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0045727 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:0045727 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0045727 Not Cancer Driver No 37 0.24 21 5 0.238 5
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:0045727 Not Cancer Driver No 30 0.122 17 3 0.176 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 GO:0045727 Not Cancer Driver No 69 0.212 43 5 0.116 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0045727 Census, Compendium Yes 275 0.219 314 41 0.131 1
FAM129A NIBAN1 Q9BZQ8 Protein Niban 1 chr1 GO:0045727 Not Cancer Driver No 162 0.175 394 79 0.201 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0045727 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:0045727 Not Cancer Driver No 106 0.16 6 1 0.167 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0045727 Not Cancer Driver No 124 0.196 327 70 0.214 3
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0045727 Not Cancer Driver No 88 0.142 312 53 0.17 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 GO:0045727 Not Cancer Driver No 68 0.101 388 42 0.108 0
GUF1 GUF1 Q8N442 Translation factor GUF1, mitochondrial chr4 GO:0045727 Not Cancer Driver No 75 0.112 38 5 0.132 1
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0045727 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0045727 Not Cancer Driver No 77 0.093 504 45 0.089 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0045727 Not Cancer Driver No 141 0.244 298 80 0.268 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045727 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0045727 Not Cancer Driver No 49 0.153 84 12 0.143 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0045727 Not Cancer Driver No 166 0.141 26 0 0.0 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0045727 Not Cancer Driver No 67 0.145 19 5 0.263 0
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 GO:0045727 Not Cancer Driver No 86 0.199 160 31 0.194 18
LARP1B LARP1B Q659C4 La-related protein 1B chr4 GO:0045727 Not Cancer Driver No 91 0.1 651 70 0.108 0
LARP4B LARP4B Q92615 La-related protein 4B chr10 GO:0045727 Census Yes 127 0.172 521 91 0.175 0
LARP4_ENST00000398473 LARP4 Q71RC2 La-related protein 4 chr12 GO:0045727 Not Cancer Driver No 86 0.119 486 53 0.109 0
LARP6 LARP6 Q9BRS8 La-related protein 6 chr15 GO:0045727 Not Cancer Driver No 64 0.13 329 48 0.146 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0045727 Not Cancer Driver No 37 0.177 86 12 0.14 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0045727 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0045727 Not Cancer Driver No 74 0.128 274 29 0.106 0
METTL5 METTL5 Q9NRN9 rRNA N6-adenosine-methyltransferase METTL5 chr2 GO:0045727 Not Cancer Driver No 19 0.091 0 0 0.0 0
MIF4GD_ENST00000325102 MIF4GD A9UHW6 MIF4G domain-containing protein chr17 GO:0045727 Not Cancer Driver No 23 0.104 12 1 0.083 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:0045727 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0045727 Not Cancer Driver No 46 0.111 51 7 0.137 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0045727 Census, Compendium Yes 379 0.149 296 37 0.125 18
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0045727 Not Cancer Driver No 109 0.106 142 18 0.127 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0045727 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0045727 Not Cancer Driver No 89 0.234 88 19 0.216 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0045727 Not Cancer Driver No 26 0.089 215 21 0.098 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0045727 Census, Compendium Yes 29 0.099 249 22 0.088 0
NSUN5_ENST00000252594 NSUN5 Q96P11 28S rRNA (cytosine-C(5))-methyltransferase chr7 GO:0045727 Not Cancer Driver No 52 0.121 47 7 0.149 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0045727 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0045727 Not Cancer Driver No 67 0.14 259 36 0.139 0
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:0045727 Not Cancer Driver No 181 0.137 412 62 0.15 0
PCIF1 PCIF1 Q9H4Z3 mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase chr20 GO:0045727 Not Cancer Driver No 77 0.109 288 37 0.128 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0045727 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0045727 Not Cancer Driver No 138 0.142 232 38 0.164 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0045727 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 GO:0045727 Not Cancer Driver No 181 0.169 133 32 0.241 1
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0045727 Not Cancer Driver No 273 0.149 304 35 0.115 0
POLDIP3_ENST00000252115 POLDIP3 Q9BY77 Polymerase delta-interacting protein 3 chr22 GO:0045727 Not Cancer Driver No 39 0.093 301 29 0.096 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0045727 Not Cancer Driver No 83 0.123 628 72 0.115 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0045727 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRR16 PRR16 Q569H4 Protein Largen chr5 GO:0045727 Not Cancer Driver No 103 0.339 278 99 0.356 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0045727 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0045727 Not Cancer Driver No 161 0.16 261 37 0.142 0
PYM1 PYM1 Q9BRP8 Partner of Y14 and mago chr12 GO:0045727 Not Cancer Driver No 22 0.108 204 22 0.108 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX GO:0045727 Not Cancer Driver No 22 0.14 134 18 0.134 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0045727 Not Cancer Driver No 19 0.041 87 7 0.08 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0045727 Census, Compendium Yes 99 0.513 46 13 0.283 2
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:0045727 Not Cancer Driver No 46 0.102 83 11 0.133 1
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0045727 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0045727 Census Yes 57 0.192 96 17 0.177 2
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:0045727 Not Cancer Driver No 4 0.048 22 2 0.091 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX GO:0045727 Not Cancer Driver No 32 0.122 35 6 0.171 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0045727 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0045727 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0045727 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0045727 Not Cancer Driver No 54 0.143 97 15 0.155 0
SAMD4A SAMD4A Q9UPU9 Protein Smaug homolog 1 chr14 GO:0045727 Not Cancer Driver No 83 0.116 473 55 0.116 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0045727 Not Cancer Driver No 6 0.091 30 2 0.067 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0045727 Not Cancer Driver No 28 0.059 400 24 0.06 4
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0045727 Not Cancer Driver No 93 0.149 285 39 0.137 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0045727 Not Cancer Driver No 45 0.123 203 22 0.108 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0045727 Not Cancer Driver No 106 0.137 442 43 0.097 0
TENT5B TENT5B Q96A09 Terminal nucleotidyltransferase 5B chr1 GO:0045727 Not Cancer Driver No 52 0.122 57 6 0.105 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0045727 Not Cancer Driver No 188 0.161 320 58 0.181 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045727 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0045727 Not Cancer Driver No 35 0.101 214 18 0.084 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0045727 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0045727 Not Cancer Driver No 37 0.112 73 7 0.096 0
UCN UCN P55089 Urocortin chr2 GO:0045727 Not Cancer Driver No 7 0.056 61 4 0.066 0
UPF3A UPF3A Q9H1J1 Regulator of nonsense transcripts 3A chr13 GO:0045727 Not Cancer Driver No 31 0.065 378 21 0.056 0
UPF3B UPF3B Q9BZI7 Regulator of nonsense transcripts 3B chrX GO:0045727 Not Cancer Driver No 98 0.203 428 91 0.213 1
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0045727 Not Cancer Driver No 10 0.079 41 1 0.024 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0045727 Not Cancer Driver No 98 0.119 394 42 0.107 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0045727 Not Cancer Driver No 84 0.18 316 57 0.18 1
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0045727 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0045727 Not Cancer Driver No 49 0.132 359 47 0.131 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0045727 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0045727 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0045727 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:0045727 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZCCHC4 ZCCHC4 Q9H5U6 rRNA N6-adenosine-methyltransferase ZCCHC4 chr4 GO:0045727 Not Cancer Driver No 57 0.111 69 4 0.058 0