Total number of protein in "GO:0045666" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRA2B | ADRA2B | P18089 | Alpha-2B adrenergic receptor | chr2 | GO:0045666 | Not Cancer Driver | No | 73 | 0.162 | 136 | 20 | 0.147 | 0 |
| ADRA2C | ADRA2C | P18825 | Alpha-2C adrenergic receptor | chr4 | GO:0045666 | Not Cancer Driver | No | 47 | 0.102 | 107 | 0 | 0.0 | 0 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | GO:0045666 | Not Cancer Driver | No | 146 | 0.148 | 450 | 70 | 0.156 | 0 |
| ASCL1 | ASCL1 | P50553 | Achaete-scute homolog 1 | chr12 | GO:0045666 | Not Cancer Driver | No | 33 | 0.14 | 182 | 24 | 0.132 | 0 |
| ATOH1 | ATOH1 | Q92858 | Transcription factor ATOH1 | chr4 | GO:0045666 | Not Cancer Driver | No | 63 | 0.178 | 327 | 55 | 0.168 | 0 |
| BCL6_ENST00000232014 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0045666 | Census, Compendium | Yes | 134 | 0.19 | 328 | 67 | 0.204 | 0 |
| BEND6 | BEND6 | Q5SZJ8 | BEN domain-containing protein 6 | chr6 | GO:0045666 | Not Cancer Driver | No | 60 | 0.215 | 245 | 56 | 0.229 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0045666 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0045666 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMP6 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0045666 | Not Cancer Driver | No | 95 | 0.185 | 226 | 51 | 0.226 | 0 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0045666 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BRINP1 | BRINP1 | O60477 | BMP/retinoic acid-inducible neural-specific protein 1 | chr9 | GO:0045666 | Not Cancer Driver | No | 273 | 0.359 | 36 | 17 | 0.472 | 0 |
| BRINP2 | BRINP2 | Q9C0B6 | BMP/retinoic acid-inducible neural-specific protein 2 | chr1 | GO:0045666 | Not Cancer Driver | No | 271 | 0.346 | 13 | 2 | 0.154 | 0 |
| BRINP3 | BRINP3 | Q76B58 | BMP/retinoic acid-inducible neural-specific protein 3 | chr1 | GO:0045666 | Not Cancer Driver | No | 439 | 0.573 | 15 | 10 | 0.667 | 0 |
| CPNE1_ENST00000352393 | CPNE1 | Q99829 | Copine-1 | chr20 | GO:0045666 | Not Cancer Driver | No | 74 | 0.138 | 80 | 7 | 0.087 | 0 |
| CSNK1D | CSNK1D | P48730 | Casein kinase I isoform delta | chr17 | GO:0045666 | Not Cancer Driver | No | 59 | 0.142 | 132 | 16 | 0.121 | 2 |
| CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0045666 | Not Cancer Driver | No | 62 | 0.149 | 133 | 18 | 0.135 | 0 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0045666 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CYB5D2 | CYB5D2 | Q8WUJ1 | Neuferricin | chr17 | GO:0045666 | Not Cancer Driver | No | 31 | 0.117 | 71 | 5 | 0.07 | 0 |
| DAB1_ENST00000371231 | DAB1 | O75553 | Disabled homolog 1 | chr1 | GO:0045666 | Not Cancer Driver | No | 200 | 0.34 | 393 | 143 | 0.364 | 0 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0045666 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DLX1 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0045666 | Not Cancer Driver | No | 25 | 0.098 | 183 | 21 | 0.115 | 0 |
| DLX2 | DLX2 | Q07687 | Homeobox protein DLX-2 | chr2 | GO:0045666 | Not Cancer Driver | No | 46 | 0.14 | 262 | 38 | 0.145 | 0 |
| DUOXA1_ENST00000560572 | DUOXA1 | Q1HG43 | Dual oxidase maturation factor 1 | chr15 | GO:0045666 | Not Cancer Driver | No | 40 | 0.117 | 38 | 7 | 0.184 | 0 |
| ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | GO:0045666 | Not Cancer Driver | No | 104 | 0.114 | 284 | 33 | 0.116 | 0 |
| EIF4G1_ENST00000346169 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0045666 | Not Cancer Driver | No | 229 | 0.143 | 1079 | 153 | 0.142 | 2 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0045666 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0045666 | Not Cancer Driver | No | 66 | 0.168 | 277 | 49 | 0.177 | 0 |
| FEZF1 | FEZF1 | A0PJY2 | Fez family zinc finger protein 1 | chr7 | GO:0045666 | Not Cancer Driver | No | 77 | 0.162 | 151 | 27 | 0.179 | 1 |
| FEZF2_ENST00000475839 | FEZF2 | Q8TBJ5 | Fez family zinc finger protein 2 | chr3 | GO:0045666 | Not Cancer Driver | No | 65 | 0.142 | 144 | 14 | 0.097 | 0 |
| FGF20 | FGF20 | Q9NP95 | Fibroblast growth factor 20 | chr8 | GO:0045666 | Not Cancer Driver | No | 25 | 0.118 | 57 | 3 | 0.053 | 0 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0045666 | Census, Compendium | Yes | 152 | 0.185 | 230 | 43 | 0.187 | 74 |
| FOXA1 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | GO:0045666 | Census, Compendium | Yes | 100 | 0.212 | 295 | 53 | 0.18 | 0 |
| FOXG1 | FOXG1 | P55316 | Forkhead box protein G1 | chr14 | GO:0045666 | Not Cancer Driver | No | 132 | 0.27 | 322 | 79 | 0.245 | 2 |
| GATA2_ENST00000487848 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0045666 | Census, Compendium | Yes | 72 | 0.15 | 370 | 49 | 0.132 | 6 |
| GDF5_ENST00000374369 | GDF5 | P43026 | Growth/differentiation factor 5 | chr20 | GO:0045666 | Not Cancer Driver | No | 104 | 0.208 | 255 | 50 | 0.196 | 24 |
| GDF6 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0045666 | Not Cancer Driver | No | 91 | 0.2 | 225 | 46 | 0.204 | 14 |
| GDF7 | GDF7 | Q7Z4P5 | Growth/differentiation factor 7 | chr2 | GO:0045666 | Not Cancer Driver | No | 33 | 0.073 | 213 | 8 | 0.038 | 0 |
| GDPD5_ENST00000529721 | GDPD5 | Q8WTR4 | Glycerophosphodiester phosphodiesterase domain-containing protein 5 | chr11 | GO:0045666 | Not Cancer Driver | No | 74 | 0.122 | 65 | 11 | 0.169 | 0 |
| GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | GO:0045666 | Not Cancer Driver | No | 82 | 0.203 | 75 | 19 | 0.253 | 0 |
| HEYL | HEYL | Q9NQ87 | Hairy/enhancer-of-split related with YRPW motif-like protein | chr1 | GO:0045666 | Not Cancer Driver | No | 44 | 0.134 | 198 | 19 | 0.096 | 0 |
| HMG20B | HMG20B | Q9P0W2 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related | chr19 | GO:0045666 | Not Cancer Driver | No | 27 | 0.085 | 237 | 18 | 0.076 | 0 |
| HOXD3 | HOXD3 | P31249 | Homeobox protein Hox-D3 | chr2 | GO:0045666 | Not Cancer Driver | No | 68 | 0.157 | 354 | 64 | 0.181 | 0 |
| IMPACT | IMPACT | Q9P2X3 | Protein IMPACT | chr18 | GO:0045666 | Not Cancer Driver | No | 49 | 0.153 | 84 | 12 | 0.143 | 0 |
| IRX3 | IRX3 | P78415 | Iroquois-class homeodomain protein IRX-3 | chr16 | GO:0045666 | Not Cancer Driver | No | 38 | 0.076 | 407 | 32 | 0.079 | 0 |
| KCTD11 | KCTD11 | Q693B1 | BTB/POZ domain-containing protein KCTD11 | chr17 | GO:0045666 | Not Cancer Driver | No | 35 | 0.151 | 54 | 4 | 0.074 | 0 |
| KDM4A | KDM4A | O75164 | Lysine-specific demethylase 4A | chr1 | GO:0045666 | Not Cancer Driver | No | 122 | 0.115 | 337 | 44 | 0.131 | 0 |
| LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0045666 | Not Cancer Driver | No | 37 | 0.177 | 86 | 12 | 0.14 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0045666 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0045666 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
| MMD | MMD | Q15546 | Monocyte to macrophage differentiation factor | chr17 | GO:0045666 | Not Cancer Driver | No | 30 | 0.126 | 0 | 0 | 0.0 | 0 |
| MMD2 | MMD2 | Q8IY49 | Monocyte to macrophage differentiation factor 2 | chr7 | GO:0045666 | Not Cancer Driver | No | 58 | 0.215 | 0 | 0 | 0.0 | 0 |
| NAP1L2 | NAP1L2 | Q9ULW6 | Nucleosome assembly protein 1-like 2 | chrX | GO:0045666 | Not Cancer Driver | No | 124 | 0.27 | 178 | 55 | 0.309 | 0 |
| NBL1_ENST00000602662 | NBL1 | P41271 | Neuroblastoma suppressor of tumorigenicity 1 | chr1 | GO:0045666 | Not Cancer Driver | No | 18 | 0.099 | 64 | 4 | 0.062 | 0 |
| NCOA1_ENST00000348332 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | GO:0045666 | Census, Compendium | Yes | 188 | 0.13 | 1217 | 149 | 0.122 | 0 |
| NEUROD1 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0045666 | Not Cancer Driver | No | 84 | 0.236 | 202 | 52 | 0.257 | 2 |
| NEUROD2 | NEUROD2 | Q15784 | Neurogenic differentiation factor 2 | chr17 | GO:0045666 | Not Cancer Driver | No | 26 | 0.068 | 210 | 14 | 0.067 | 2 |
| NEUROG1 | NEUROG1 | Q92886 | Neurogenin-1 | chr5 | GO:0045666 | Not Cancer Driver | No | 27 | 0.114 | 178 | 18 | 0.101 | 0 |
| NEUROG3 | NEUROG3 | Q9Y4Z2 | Neurogenin-3 | chr10 | GO:0045666 | Not Cancer Driver | No | 53 | 0.248 | 156 | 34 | 0.218 | 2 |
| NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0045666 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
| NKX2-2 | NKX2-2 | O95096 | Homeobox protein Nkx-2.2 | chr20 | GO:0045666 | Not Cancer Driver | No | 84 | 0.308 | 206 | 65 | 0.316 | 0 |
| NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | GO:0045666 | Not Cancer Driver | No | 48 | 0.148 | 181 | 22 | 0.122 | 55 |
| NKX6-1 | NKX6-1 | P78426 | Homeobox protein Nkx-6.1 | chr4 | GO:0045666 | Not Cancer Driver | No | 38 | 0.104 | 325 | 34 | 0.105 | 0 |
| NRCAM_ENST00000425651 | NRCAM | Q92823 | Neuronal cell adhesion molecule | chr7 | GO:0045666 | Not Cancer Driver | No | 210 | 0.161 | 471 | 75 | 0.159 | 0 |
| PCP4 | PCP4 | P48539 | Calmodulin regulator protein PCP4 | chr21 | GO:0045666 | Not Cancer Driver | No | 16 | 0.258 | 62 | 16 | 0.258 | 0 |
| PHOX2B | PHOX2B | Q99453 | Paired mesoderm homeobox protein 2B | chr4 | GO:0045666 | Census | Yes | 59 | 0.188 | 219 | 44 | 0.201 | 2 |
| PROX1 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0045666 | Not Cancer Driver | No | 182 | 0.247 | 537 | 141 | 0.263 | 0 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0045666 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0045666 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0045666 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0045666 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0045666 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| SH3GL3_ENST00000427482 | SH3GL3 | Q99963 | Endophilin-A3 | chr15 | GO:0045666 | Not Cancer Driver | No | 88 | 0.254 | 83 | 23 | 0.277 | 0 |
| SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0045666 | Compendium | Yes | 172 | 0.135 | 617 | 73 | 0.118 | 0 |
| SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0045666 | Not Cancer Driver | No | 32 | 0.162 | 61 | 2 | 0.033 | 0 |
| SOX11 | SOX11 | P35716 | Transcription factor SOX-11 | chr2 | GO:0045666 | Not Cancer Driver | No | 61 | 0.138 | 368 | 53 | 0.144 | 2 |
| SPAG9 | SPAG9 | O60271 | C-Jun-amino-terminal kinase-interacting protein 4 | chr17 | GO:0045666 | Not Cancer Driver | No | 128 | 0.097 | 841 | 81 | 0.096 | 0 |
| TCF12_ENST00000267811 | TCF12 | Q99081 | Transcription factor 12 | chr15 | GO:0045666 | Census | Yes | 105 | 0.154 | 680 | 105 | 0.154 | 3 |
| TCF3 | TCF3 | P15923 | Transcription factor E2-alpha | chr19 | GO:0045666 | Census | Yes | 52 | 0.08 | 649 | 52 | 0.08 | 0 |
| TCF4_ENST00000564999 | TCF4 | P15884 | Transcription factor 4 | chr18 | GO:0045666 | Compendium | Yes | 141 | 0.211 | 662 | 136 | 0.205 | 13 |
| TGIF2_ENST00000611732 | TGIF2 | Q9GZN2 | Homeobox protein TGIF2 | chr20 | GO:0045666 | Not Cancer Driver | No | 37 | 0.156 | 171 | 23 | 0.135 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0045666 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TRPC5 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0045666 | Not Cancer Driver | No | 255 | 0.262 | 148 | 32 | 0.216 | 0 |
| VWC2 | VWC2 | Q2TAL6 | Brorin | chr7 | GO:0045666 | Not Cancer Driver | No | 51 | 0.157 | 127 | 7 | 0.055 | 0 |
| VWC2L | VWC2L | B2RUY7 | von Willebrand factor C domain-containing protein 2-like | chr2 | GO:0045666 | Not Cancer Driver | No | 75 | 0.338 | 10 | 4 | 0.4 | 0 |
| ZC4H2 | ZC4H2 | Q9NQZ6 | Zinc finger C4H2 domain-containing protein | chrX | GO:0045666 | Not Cancer Driver | No | 60 | 0.268 | 136 | 43 | 0.316 | 13 |
| ZEB1_ENST00000320985 | ZEB1 | P37275 | Zinc finger E-box-binding homeobox 1 | chr10 | GO:0045666 | Census, Compendium | Yes | 246 | 0.219 | 831 | 200 | 0.241 | 8 |