Total number of protein in "GO:0045229" GO term: 105
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0045229 | Not Cancer Driver | No | 88 | 0.118 | 156 | 20 | 0.128 | 4 |
| ADAM15 | ADAM15 | Q13444 | Disintegrin and metalloproteinase domain-containing protein 15 | chr1 | GO:0045229 | Not Cancer Driver | No | 104 | 0.121 | 213 | 29 | 0.136 | 0 |
| ADAM8 | ADAM8 | P78325 | Disintegrin and metalloproteinase domain-containing protein 8 | chr10 | GO:0045229 | Not Cancer Driver | No | 82 | 0.1 | 230 | 13 | 0.057 | 0 |
| ADAMTS15 | ADAMTS15 | Q8TE58 | A disintegrin and metalloproteinase with thrombospondin motifs 15 | chr11 | GO:0045229 | Not Cancer Driver | No | 127 | 0.134 | 141 | 25 | 0.177 | 0 |
| ADAMTS4 | ADAMTS4 | O75173 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | chr1 | GO:0045229 | Not Cancer Driver | No | 134 | 0.16 | 159 | 27 | 0.17 | 0 |
| ADAMTS5 | ADAMTS5 | Q9UNA0 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | chr21 | GO:0045229 | Not Cancer Driver | No | 227 | 0.244 | 148 | 33 | 0.223 | 0 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0045229 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | GO:0045229 | Not Cancer Driver | No | 45 | 0.129 | 95 | 7 | 0.074 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0045229 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0045229 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CMA1 | CMA1 | P23946 | Chymase | chr14 | GO:0045229 | Not Cancer Driver | No | 47 | 0.19 | 9 | 1 | 0.111 | 0 |
| COL1A2 | COL1A2 | P08123 | Collagen alpha-2(I) chain | chr7 | GO:0045229 | Not Cancer Driver | No | 372 | 0.272 | 1159 | 329 | 0.284 | 83 |
| COL3A1 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0045229 | Census | Yes | 402 | 0.274 | 1182 | 337 | 0.285 | 103 |
| COL4A1 | COL4A1 | P02462 | Collagen alpha-1(IV) chain | chr13 | GO:0045229 | Not Cancer Driver | No | 349 | 0.209 | 1457 | 310 | 0.213 | 32 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0045229 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
| COL4A4 | COL4A4 | P53420 | Collagen alpha-4(IV) chain | chr2 | GO:0045229 | Not Cancer Driver | No | 461 | 0.273 | 1431 | 405 | 0.283 | 8 |
| CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0045229 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
| CTSK | CTSK | P43235 | Cathepsin K | chr1 | GO:0045229 | Not Cancer Driver | No | 36 | 0.109 | 24 | 4 | 0.167 | 6 |
| CTSS | CTSS | P25774 | Cathepsin S | chr1 | GO:0045229 | Not Cancer Driver | No | 54 | 0.163 | 0 | 0 | 0.0 | 0 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | GO:0045229 | Not Cancer Driver | No | 55 | 0.165 | 7 | 1 | 0.143 | 0 |
| DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0045229 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
| EFEMP2 | EFEMP2 | O95967 | EGF-containing fibulin-like extracellular matrix protein 2 | chr11 | GO:0045229 | Not Cancer Driver | No | 67 | 0.151 | 41 | 4 | 0.098 | 8 |
| ELANE_ENST00000263621 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0045229 | Not Cancer Driver | No | 39 | 0.146 | 18 | 3 | 0.167 | 89 |
| EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0045229 | Not Cancer Driver | No | 125 | 0.123 | 669 | 69 | 0.103 | 0 |
| EXOC8 | EXOC8 | Q8IYI6 | Exocyst complex component 8 | chr1 | GO:0045229 | Not Cancer Driver | No | 84 | 0.116 | 195 | 21 | 0.108 | 0 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0045229 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FBLN5 | FBLN5 | Q9UBX5 | Fibulin-5 | chr14 | GO:0045229 | Not Cancer Driver | No | 77 | 0.172 | 11 | 2 | 0.182 | 16 |
| FERMT1 | FERMT1 | Q9BQL6 | Fermitin family homolog 1 | chr20 | GO:0045229 | Not Cancer Driver | No | 100 | 0.148 | 65 | 8 | 0.123 | 2 |
| FKBP10 | FKBP10 | Q96AY3 | Peptidyl-prolyl cis-trans isomerase FKBP10 | chr17 | GO:0045229 | Not Cancer Driver | No | 60 | 0.103 | 134 | 8 | 0.06 | 3 |
| FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | GO:0045229 | Not Cancer Driver | No | 43 | 0.101 | 122 | 15 | 0.123 | 0 |
| FLRT2_ENST00000554746 | FLRT2 | O43155 | Leucine-rich repeat transmembrane protein FLRT2 | chr14 | GO:0045229 | Not Cancer Driver | No | 225 | 0.341 | 80 | 21 | 0.263 | 0 |
| FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | GO:0045229 | Not Cancer Driver | No | 93 | 0.117 | 283 | 35 | 0.124 | 0 |
| GAS2 | GAS2 | O43903 | Growth arrest-specific protein 2 | chr11 | GO:0045229 | Not Cancer Driver | No | 73 | 0.233 | 92 | 16 | 0.174 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0045229 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GPM6B_ENST00000356942 | GPM6B | Q13491 | Neuronal membrane glycoprotein M6-b | chrX | GO:0045229 | Not Cancer Driver | No | 39 | 0.147 | 14 | 3 | 0.214 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0045229 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HAPLN2 | HAPLN2 | Q9GZV7 | Hyaluronan and proteoglycan link protein 2 | chr1 | GO:0045229 | Not Cancer Driver | No | 27 | 0.079 | 35 | 1 | 0.029 | 0 |
| HAS1 | HAS1 | Q92839 | Hyaluronan synthase 1 | chr19 | GO:0045229 | Not Cancer Driver | No | 115 | 0.199 | 9 | 0 | 0.0 | 0 |
| HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0045229 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
| HAS3 | HAS3 | O00219 | Hyaluronan synthase 3 | chr16 | GO:0045229 | Not Cancer Driver | No | 63 | 0.114 | 13 | 0 | 0.0 | 0 |
| HMCN1 | HMCN1 | Q96RW7 | Hemicentin-1 | chr1 | GO:0045229 | Not Cancer Driver | No | 1020 | 0.181 | 943 | 167 | 0.177 | 1 |
| HPN_ENST00000392226 | HPN | P05981 | Serine protease hepsin | chr19 | GO:0045229 | Not Cancer Driver | No | 60 | 0.144 | 12 | 0 | 0.0 | 0 |
| HRNR | HRNR | Q86YZ3 | Hornerin | chr1 | GO:0045229 | Not Cancer Driver | No | 612 | 0.215 | 2767 | 601 | 0.217 | 0 |
| IHH | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0045229 | Not Cancer Driver | No | 58 | 0.141 | 111 | 15 | 0.135 | 6 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0045229 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KIF9_ENST00000452770 | KIF9 | Q9HAQ2 | Kinesin-like protein KIF9 | chr3 | GO:0045229 | Not Cancer Driver | No | 94 | 0.119 | 213 | 42 | 0.197 | 0 |
| KLK4 | KLK4 | Q9Y5K2 | Kallikrein-4 | chr19 | GO:0045229 | Not Cancer Driver | No | 47 | 0.185 | 9 | 3 | 0.333 | 0 |
| KLK5_ENST00000593428 | KLK5 | Q9Y337 | Kallikrein-5 | chr19 | GO:0045229 | Not Cancer Driver | No | 69 | 0.235 | 75 | 16 | 0.213 | 0 |
| KLK7 | KLK7 | P49862 | Kallikrein-7 | chr19 | GO:0045229 | Not Cancer Driver | No | 43 | 0.17 | 38 | 8 | 0.211 | 0 |
| LAMB1 | LAMB1 | P07942 | Laminin subunit beta-1 | chr7 | GO:0045229 | Not Cancer Driver | No | 240 | 0.134 | 418 | 50 | 0.12 | 0 |
| LAMB2 | LAMB2 | P55268 | Laminin subunit beta-2 | chr3 | GO:0045229 | Not Cancer Driver | No | 234 | 0.13 | 463 | 67 | 0.145 | 9 |
| LAMB3_ENST00000367030 | LAMB3 | Q13751 | Laminin subunit beta-3 | chr1 | GO:0045229 | Not Cancer Driver | No | 226 | 0.193 | 376 | 66 | 0.176 | 4 |
| LAMB4 | LAMB4 | A4D0S4 | Laminin subunit beta-4 | chr7 | GO:0045229 | Not Cancer Driver | No | 344 | 0.195 | 247 | 53 | 0.215 | 0 |
| LAMC1 | LAMC1 | P11047 | Laminin subunit gamma-1 | chr1 | GO:0045229 | Not Cancer Driver | No | 232 | 0.144 | 562 | 94 | 0.167 | 0 |
| LCP1 | LCP1 | P13796 | Plastin-2 | chr13 | GO:0045229 | Census | Yes | 99 | 0.158 | 73 | 11 | 0.151 | 0 |
| LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | GO:0045229 | Compendium | Yes | 44 | 0.106 | 172 | 11 | 0.064 | 4 |
| LTBP3 | LTBP3 | Q9NS15 | Latent-transforming growth factor beta-binding protein 3 | chr11 | GO:0045229 | Not Cancer Driver | No | 108 | 0.083 | 356 | 22 | 0.062 | 0 |
| MFAP4_ENST00000299610 | MFAP4 | P55083 | Microfibril-associated glycoprotein 4 | chr17 | GO:0045229 | Not Cancer Driver | No | 35 | 0.137 | 0 | 0 | 0.0 | 0 |
| MMP1 | MMP1 | P03956 | Interstitial collagenase | chr11 | GO:0045229 | Not Cancer Driver | No | 83 | 0.177 | 113 | 18 | 0.159 | 0 |
| MMP10 | MMP10 | P09238 | Stromelysin-2 | chr11 | GO:0045229 | Not Cancer Driver | No | 88 | 0.185 | 38 | 9 | 0.237 | 0 |
| MMP11 | MMP11 | P24347 | Stromelysin-3 | chr22 | GO:0045229 | Not Cancer Driver | No | 63 | 0.129 | 122 | 22 | 0.18 | 0 |
| MMP12 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0045229 | Not Cancer Driver | No | 100 | 0.213 | 29 | 5 | 0.172 | 0 |
| MMP13 | MMP13 | P45452 | Collagenase 3 | chr11 | GO:0045229 | Not Cancer Driver | No | 113 | 0.24 | 59 | 16 | 0.271 | 5 |
| MMP14 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0045229 | Not Cancer Driver | No | 64 | 0.11 | 118 | 11 | 0.093 | 1 |
| MMP15 | MMP15 | P51511 | Matrix metalloproteinase-15 | chr16 | GO:0045229 | Not Cancer Driver | No | 78 | 0.117 | 205 | 23 | 0.112 | 0 |
| MMP19 | MMP19 | Q99542 | Matrix metalloproteinase-19 | chr12 | GO:0045229 | Not Cancer Driver | No | 94 | 0.185 | 98 | 20 | 0.204 | 0 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0045229 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| MMP20 | MMP20 | O60882 | Matrix metalloproteinase-20 | chr11 | GO:0045229 | Not Cancer Driver | No | 79 | 0.164 | 69 | 8 | 0.116 | 0 |
| MMP3 | MMP3 | P08254 | Stromelysin-1 | chr11 | GO:0045229 | Not Cancer Driver | No | 99 | 0.208 | 66 | 14 | 0.212 | 0 |
| MMP7 | MMP7 | P09237 | Matrilysin | chr11 | GO:0045229 | Not Cancer Driver | No | 39 | 0.146 | 70 | 2 | 0.029 | 0 |
| MMP8 | MMP8 | P22894 | Neutrophil collagenase | chr11 | GO:0045229 | Not Cancer Driver | No | 73 | 0.156 | 115 | 19 | 0.165 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0045229 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MPV17 | MPV17 | P39210 | Protein Mpv17 | chr2 | GO:0045229 | Not Cancer Driver | No | 21 | 0.119 | 0 | 0 | 0.0 | 16 |
| MYH11_ENST00000300036 | MYH11 | P35749 | Myosin-11 | chr16 | GO:0045229 | Census, Compendium | Yes | 353 | 0.179 | 1180 | 201 | 0.17 | 2 |
| MYO1E | MYO1E | Q12965 | Unconventional myosin-Ie | chr15 | GO:0045229 | Not Cancer Driver | No | 137 | 0.124 | 229 | 14 | 0.061 | 1 |
| NID1 | NID1 | P14543 | Nidogen-1 | chr1 | GO:0045229 | Not Cancer Driver | No | 246 | 0.197 | 340 | 72 | 0.212 | 0 |
| NID2 | NID2 | Q14112 | Nidogen-2 | chr14 | GO:0045229 | Not Cancer Driver | No | 270 | 0.196 | 415 | 96 | 0.231 | 0 |
| NOXO1 | NOXO1 | Q8NFA2 | NADPH oxidase organizer 1 | chr16 | GO:0045229 | Not Cancer Driver | No | 29 | 0.077 | 182 | 9 | 0.049 | 0 |
| NPHS1 | NPHS1 | O60500 | Nephrin | chr19 | GO:0045229 | Not Cancer Driver | No | 230 | 0.185 | 484 | 108 | 0.223 | 62 |
| NTN4 | NTN4 | Q9HB63 | Netrin-4 | chr12 | GO:0045229 | Not Cancer Driver | No | 114 | 0.182 | 8 | 1 | 0.125 | 0 |
| NTNG1_ENST00000370073 | NTNG1 | Q9Y2I2 | Netrin-G1 | chr1 | GO:0045229 | Not Cancer Driver | No | 149 | 0.276 | 1 | 0 | 0.0 | 0 |
| NTNG2 | NTNG2 | Q96CW9 | Netrin-G2 | chr9 | GO:0045229 | Not Cancer Driver | No | 91 | 0.172 | 8 | 4 | 0.5 | 7 |
| PBXIP1 | PBXIP1 | Q96AQ6 | Pre-B-cell leukemia transcription factor-interacting protein 1 | chr1 | GO:0045229 | Not Cancer Driver | No | 100 | 0.137 | 605 | 86 | 0.142 | 0 |
| PLG | PLG | P00747 | Plasminogen | chr6 | GO:0045229 | Not Cancer Driver | No | 242 | 0.299 | 230 | 64 | 0.278 | 9 |
| PLOD3 | PLOD3 | O60568 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 | chr7 | GO:0045229 | Not Cancer Driver | No | 108 | 0.146 | 65 | 8 | 0.123 | 1 |
| PRSS1 | PRSS1 | P07477 | Serine protease 1 | chr7 | GO:0045229 | Not Cancer Driver | No | 121 | 0.49 | 0 | 0 | 0.0 | 12 |
| PRSS2_ENST00000539842 | PRSS2 | P07478 | Trypsin-2 | chr7 | GO:0045229 | Not Cancer Driver | No | 51 | 0.206 | 9 | 1 | 0.111 | 0 |
| PXDN | PXDN | Q92626 | Peroxidasin homolog | chr2 | GO:0045229 | Not Cancer Driver | No | 332 | 0.224 | 307 | 77 | 0.251 | 1 |
| QSOX1 | QSOX1 | O00391 | Sulfhydryl oxidase 1 | chr1 | GO:0045229 | Not Cancer Driver | No | 93 | 0.124 | 189 | 22 | 0.116 | 0 |
| RAMP2 | RAMP2 | O60895 | Receptor activity-modifying protein 2 | chr17 | GO:0045229 | Not Cancer Driver | No | 18 | 0.103 | 34 | 6 | 0.176 | 0 |
| RIC8A_ENST00000526104 | RIC8A | Q9NPQ8 | Synembryn-A | chr11 | GO:0045229 | Not Cancer Driver | No | 63 | 0.119 | 163 | 23 | 0.141 | 0 |
| SH3PXD2B | SH3PXD2B | A1X283 | SH3 and PX domain-containing protein 2B | chr5 | GO:0045229 | Not Cancer Driver | No | 122 | 0.134 | 660 | 101 | 0.153 | 1 |
| SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0045229 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
| SPINT2 | SPINT2 | O43291 | Kunitz-type protease inhibitor 2 | chr19 | GO:0045229 | Not Cancer Driver | No | 46 | 0.183 | 25 | 3 | 0.12 | 1 |
| SULF1_ENST00000458141 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0045229 | Not Cancer Driver | No | 246 | 0.282 | 269 | 71 | 0.264 | 0 |
| SULF2_ENST00000484875 | SULF2 | Q8IWU5 | Extracellular sulfatase Sulf-2 | chr20 | GO:0045229 | Not Cancer Driver | No | 145 | 0.167 | 142 | 18 | 0.127 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0045229 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TGM1 | TGM1 | P22735 | Protein-glutamine gamma-glutamyltransferase K | chr14 | GO:0045229 | Not Cancer Driver | No | 118 | 0.144 | 230 | 37 | 0.161 | 65 |
| TGM3 | TGM3 | Q08188 | Protein-glutamine gamma-glutamyltransferase E | chr20 | GO:0045229 | Not Cancer Driver | No | 141 | 0.203 | 85 | 19 | 0.224 | 0 |
| THSD4 | THSD4 | Q6ZMP0 | Thrombospondin type-1 domain-containing protein 4 | chr15 | GO:0045229 | Not Cancer Driver | No | 172 | 0.169 | 410 | 62 | 0.151 | 0 |
| TMPRSS6_ENST00000346753 | TMPRSS6 | Q8IU80 | Transmembrane protease serine 6 | chr22 | GO:0045229 | Not Cancer Driver | No | 125 | 0.154 | 36 | 7 | 0.194 | 25 |
| TNXB_ENST00000375244 | TNXB | P22105 | Tenascin-X | chr6 | GO:0045229 | Not Cancer Driver | No | 666 | 0.157 | 2794 | 498 | 0.178 | 5 |
| TPSAB1 | TPSAB1 | Q15661 | Tryptase alpha/beta-1 | chr16 | GO:0045229 | Not Cancer Driver | No | 40 | 0.145 | 28 | 6 | 0.214 | 0 |
| WASHC1 | WASHC1 | A8K0Z3 | WASH complex subunit 1 | chr9 | GO:0045229 | Not Cancer Driver | No | 6 | 0.013 | 336 | 6 | 0.018 | 0 |
| WDR72 | WDR72 | Q3MJ13 | WD repeat-containing protein 72 | chr15 | GO:0045229 | Not Cancer Driver | No | 217 | 0.197 | 107 | 21 | 0.196 | 0 |