Total number of protein in "GO:0045182" GO term: 97
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARS | AARS1 | P49588 | Alanine--tRNA ligase, cytoplasmic | chr16 | GO:0045182 | Not Cancer Driver | No | 97 | 0.1 | 140 | 14 | 0.1 | 5 |
| ABCF1 | ABCF1 | Q8NE71 | ATP-binding cassette sub-family F member 1 | chr6 | GO:0045182 | Not Cancer Driver | No | 106 | 0.125 | 445 | 64 | 0.144 | 0 |
| ABTB1 | ABTB1 | Q969K4 | Ankyrin repeat and BTB/POZ domain-containing protein 1 | chr3 | GO:0045182 | Not Cancer Driver | No | 58 | 0.121 | 15 | 4 | 0.267 | 0 |
| AIRE | AIRE | O43918 | Autoimmune regulator | chr21 | GO:0045182 | Not Cancer Driver | No | 71 | 0.13 | 338 | 48 | 0.142 | 19 |
| BOLL_ENST00000392296 | BOLL | Q8N9W6 | Protein boule-like | chr2 | GO:0045182 | Not Cancer Driver | No | 59 | 0.208 | 78 | 22 | 0.282 | 0 |
| CELF1_ENST00000358597 | CELF1 | Q92879 | CUGBP Elav-like family member 1 | chr11 | GO:0045182 | Not Cancer Driver | No | 56 | 0.115 | 166 | 17 | 0.102 | 0 |
| CELF4 | CELF4 | Q9BZC1 | CUGBP Elav-like family member 4 | chr18 | GO:0045182 | Not Cancer Driver | No | 107 | 0.22 | 253 | 74 | 0.292 | 0 |
| CIRBP_ENST00000586472 | CIRBP | Q14011 | Cold-inducible RNA-binding protein | chr19 | GO:0045182 | Not Cancer Driver | No | 19 | 0.11 | 129 | 13 | 0.101 | 0 |
| CNBP_ENST00000422453 | CNBP | P62633 | CCHC-type zinc finger nucleic acid binding protein | chr3 | GO:0045182 | Census | Yes | 11 | 0.062 | 19 | 0 | 0.0 | 0 |
| CPEB1_ENST00000611031 | CPEB1 | Q9BZB8 | Cytoplasmic polyadenylation element-binding protein 1 | chr15 | GO:0045182 | Not Cancer Driver | No | 90 | 0.159 | 226 | 37 | 0.164 | 0 |
| CPEB2_ENST00000507071 | CPEB2 | Q7Z5Q1 | Cytoplasmic polyadenylation element-binding protein 2 | chr4 | GO:0045182 | Not Cancer Driver | No | 66 | 0.112 | 269 | 17 | 0.063 | 0 |
| CPEB3_ENST00000265997 | CPEB3 | Q8NE35 | Cytoplasmic polyadenylation element-binding protein 3 | chr10 | GO:0045182 | Census, Compendium | Yes | 66 | 0.095 | 414 | 28 | 0.068 | 0 |
| CPEB4 | CPEB4 | Q17RY0 | Cytoplasmic polyadenylation element-binding protein 4 | chr5 | GO:0045182 | Not Cancer Driver | No | 85 | 0.117 | 443 | 54 | 0.122 | 0 |
| CTIF_ENST00000256413 | CTIF | O43310 | CBP80/20-dependent translation initiation factor | chr18 | GO:0045182 | Not Cancer Driver | No | 97 | 0.162 | 384 | 62 | 0.161 | 0 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0045182 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
| DAZ2_ENST00000382424 | DAZ2 | Q13117 | Deleted in azoospermia protein 2 | chrY | GO:0045182 | Not Cancer Driver | No | 1 | 0.002 | 72 | 0 | 0.0 | 0 |
| DAZL_ENST00000399444 | DAZL | Q92904 | Deleted in azoospermia-like | chr3 | GO:0045182 | Not Cancer Driver | No | 28 | 0.095 | 128 | 12 | 0.094 | 0 |
| DHFR | DHFR | P00374 | Dihydrofolate reductase | chr5 | GO:0045182 | Not Cancer Driver | No | 16 | 0.086 | 12 | 2 | 0.167 | 2 |
| DHX29 | DHX29 | Q7Z478 | ATP-dependent RNA helicase DHX29 | chr5 | GO:0045182 | Not Cancer Driver | No | 146 | 0.107 | 405 | 34 | 0.084 | 0 |
| EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | GO:0045182 | Not Cancer Driver | No | 109 | 0.236 | 100 | 14 | 0.14 | 0 |
| EEF1A2 | EEF1A2 | Q05639 | Elongation factor 1-alpha 2 | chr20 | GO:0045182 | Not Cancer Driver | No | 74 | 0.16 | 121 | 17 | 0.14 | 3 |
| EEF1B2_ENST00000236957 | EEF1B2 | P24534 | Elongation factor 1-beta | chr2 | GO:0045182 | Not Cancer Driver | No | 63 | 0.28 | 71 | 11 | 0.155 | 0 |
| EEF1D_ENST00000395119 | EEF1D | P29692 | Elongation factor 1-delta | chr8 | GO:0045182 | Not Cancer Driver | No | 40 | 0.142 | 153 | 22 | 0.144 | 0 |
| EEF1G | EEF1G | P26641 | Elongation factor 1-gamma | chr11 | GO:0045182 | Not Cancer Driver | No | 44 | 0.101 | 66 | 5 | 0.076 | 0 |
| EEF2 | EEF2 | P13639 | Elongation factor 2 | chr19 | GO:0045182 | Not Cancer Driver | No | 111 | 0.129 | 78 | 14 | 0.179 | 1 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0045182 | Not Cancer Driver | No | 104 | 0.143 | 311 | 39 | 0.125 | 0 |
| EEFSEC | EEFSEC | P57772 | Selenocysteine-specific elongation factor | chr3 | GO:0045182 | Not Cancer Driver | No | 80 | 0.134 | 124 | 21 | 0.169 | 0 |
| EFL1 | EFL1 | Q7Z2Z2 | Elongation factor-like GTPase 1 | chr15 | GO:0045182 | Not Cancer Driver | No | 128 | 0.114 | 329 | 37 | 0.112 | 0 |
| EIF1 | EIF1 | P41567 | Eukaryotic translation initiation factor 1 | chr17 | GO:0045182 | Not Cancer Driver | No | 13 | 0.115 | 9 | 1 | 0.111 | 0 |
| EIF1AX | EIF1AX | P47813 | Eukaryotic translation initiation factor 1A, X-chromosomal | chrX | GO:0045182 | Census, Compendium | Yes | 39 | 0.271 | 67 | 28 | 0.418 | 0 |
| EIF2AK1 | EIF2AK1 | Q9BQI3 | Eukaryotic translation initiation factor 2-alpha kinase 1 | chr7 | GO:0045182 | Not Cancer Driver | No | 87 | 0.138 | 238 | 29 | 0.122 | 0 |
| EIF2AK2_ENST00000395127 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | GO:0045182 | Not Cancer Driver | No | 59 | 0.107 | 188 | 22 | 0.117 | 0 |
| EIF2AK3 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0045182 | Not Cancer Driver | No | 149 | 0.134 | 410 | 51 | 0.124 | 1 |
| EIF2AK4 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0045182 | Not Cancer Driver | No | 156 | 0.095 | 494 | 44 | 0.089 | 2 |
| EIF2B3 | EIF2B3 | Q9NR50 | Translation initiation factor eIF-2B subunit gamma | chr1 | GO:0045182 | Not Cancer Driver | No | 54 | 0.119 | 28 | 9 | 0.321 | 5 |
| EIF2S2 | EIF2S2 | P20042 | Eukaryotic translation initiation factor 2 subunit 2 | chr20 | GO:0045182 | Not Cancer Driver | No | 37 | 0.111 | 185 | 12 | 0.065 | 0 |
| EIF2S3 | EIF2S3 | P41091 | Eukaryotic translation initiation factor 2 subunit 3 | chrX | GO:0045182 | Not Cancer Driver | No | 52 | 0.11 | 51 | 7 | 0.137 | 1 |
| EIF4A1 | EIF4A1 | P60842 | Eukaryotic initiation factor 4A-I | chr17 | GO:0045182 | Not Cancer Driver | No | 48 | 0.118 | 35 | 7 | 0.2 | 0 |
| EIF4A3 | EIF4A3 | P38919 | Eukaryotic initiation factor 4A-III | chr17 | GO:0045182 | Not Cancer Driver | No | 50 | 0.122 | 57 | 6 | 0.105 | 1 |
| EIF4E2 | EIF4E2 | O60573 | Eukaryotic translation initiation factor 4E type 2 | chr2 | GO:0045182 | Not Cancer Driver | No | 27 | 0.11 | 80 | 5 | 0.062 | 0 |
| EIF4EBP1 | EIF4EBP1 | Q13541 | Eukaryotic translation initiation factor 4E-binding protein 1 | chr8 | GO:0045182 | Not Cancer Driver | No | 8 | 0.068 | 118 | 8 | 0.068 | 0 |
| EIF4EBP2 | EIF4EBP2 | Q13542 | Eukaryotic translation initiation factor 4E-binding protein 2 | chr10 | GO:0045182 | Not Cancer Driver | No | 17 | 0.142 | 118 | 14 | 0.119 | 0 |
| EIF4EBP3 | EIF4EBP3 | O60516 | Eukaryotic translation initiation factor 4E-binding protein 3 | chr5 | GO:0045182 | Not Cancer Driver | No | 9 | 0.09 | 78 | 6 | 0.077 | 0 |
| EIF4G1_ENST00000346169 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0045182 | Not Cancer Driver | No | 229 | 0.143 | 1079 | 153 | 0.142 | 2 |
| EIF4G2_ENST00000640650 | EIF4G2 | P78344 | Eukaryotic translation initiation factor 4 gamma 2 | chr11 | GO:0045182 | Not Cancer Driver | No | 104 | 0.115 | 382 | 43 | 0.113 | 0 |
| EIF4G3_ENST00000264211 | EIF4G3 | O43432 | Eukaryotic translation initiation factor 4 gamma 3 | chr1 | GO:0045182 | Not Cancer Driver | No | 200 | 0.126 | 1018 | 127 | 0.125 | 0 |
| EIF4H | EIF4H | Q15056 | Eukaryotic translation initiation factor 4H | chr7 | GO:0045182 | Not Cancer Driver | No | 30 | 0.121 | 175 | 17 | 0.097 | 0 |
| EIF5A2 | EIF5A2 | Q9GZV4 | Eukaryotic translation initiation factor 5A-2 | chr3 | GO:0045182 | Not Cancer Driver | No | 20 | 0.131 | 28 | 4 | 0.143 | 0 |
| EIF5AL1 | EIF5AL1 | Q6IS14 | Eukaryotic translation initiation factor 5A-1-like | chr10 | GO:0045182 | Not Cancer Driver | No | 21 | 0.136 | 16 | 4 | 0.25 | 0 |
| EIF5A_ENST00000419711 | EIF5A | P63241 | Eukaryotic translation initiation factor 5A-1 | chr17 | GO:0045182 | Not Cancer Driver | No | 37 | 0.24 | 21 | 5 | 0.238 | 5 |
| ELAVL4_ENST00000371821 | ELAVL4 | P26378 | ELAV-like protein 4 | chr1 | GO:0045182 | Not Cancer Driver | No | 118 | 0.306 | 117 | 34 | 0.291 | 0 |
| ETF1 | ETF1 | P62495 | Eukaryotic peptide chain release factor subunit 1 | chr5 | GO:0045182 | Not Cancer Driver | No | 60 | 0.137 | 28 | 11 | 0.393 | 0 |
| FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | GO:0045182 | Not Cancer Driver | No | 124 | 0.196 | 327 | 70 | 0.214 | 3 |
| FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | GO:0045182 | Not Cancer Driver | No | 88 | 0.142 | 312 | 53 | 0.17 | 0 |
| FXR2 | FXR2 | P51116 | Fragile X mental retardation syndrome-related protein 2 | chr17 | GO:0045182 | Not Cancer Driver | No | 68 | 0.101 | 388 | 42 | 0.108 | 0 |
| GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | GO:0045182 | Not Cancer Driver | No | 327 | 0.122 | 117 | 16 | 0.137 | 0 |
| GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | GO:0045182 | Not Cancer Driver | No | 74 | 0.099 | 79 | 7 | 0.089 | 4 |
| GFM2_ENST00000509430 | GFM2 | Q969S9 | Ribosome-releasing factor 2, mitochondrial | chr5 | GO:0045182 | Not Cancer Driver | No | 75 | 0.096 | 100 | 10 | 0.1 | 2 |
| GSPT1_ENST00000563468 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | GO:0045182 | Not Cancer Driver | No | 42 | 0.084 | 149 | 13 | 0.087 | 0 |
| GSPT2 | GSPT2 | Q8IYD1 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | chrX | GO:0045182 | Not Cancer Driver | No | 108 | 0.172 | 270 | 47 | 0.174 | 0 |
| GTPBP1 | GTPBP1 | O00178 | GTP-binding protein 1 | chr22 | GO:0045182 | Not Cancer Driver | No | 75 | 0.112 | 263 | 26 | 0.099 | 0 |
| GTPBP2 | GTPBP2 | Q9BX10 | GTP-binding protein 2 | chr6 | GO:0045182 | Not Cancer Driver | No | 53 | 0.088 | 89 | 5 | 0.056 | 0 |
| HBS1L | HBS1L | Q9Y450 | HBS1-like protein | chr6 | GO:0045182 | Not Cancer Driver | No | 73 | 0.107 | 229 | 23 | 0.1 | 0 |
| IGF2BP1 | IGF2BP1 | Q9NZI8 | Insulin-like growth factor 2 mRNA-binding protein 1 | chr17 | GO:0045182 | Not Cancer Driver | No | 141 | 0.244 | 298 | 80 | 0.268 | 0 |
| IGF2BP2_ENST00000382199 | IGF2BP2 | Q9Y6M1 | Insulin-like growth factor 2 mRNA-binding protein 2 | chr3 | GO:0045182 | Census | Yes | 68 | 0.114 | 237 | 31 | 0.131 | 0 |
| IGF2BP3 | IGF2BP3 | O00425 | Insulin-like growth factor 2 mRNA-binding protein 3 | chr7 | GO:0045182 | Not Cancer Driver | No | 79 | 0.136 | 264 | 40 | 0.152 | 0 |
| IREB2 | IREB2 | P48200 | Iron-responsive element-binding protein 2 | chr15 | GO:0045182 | Not Cancer Driver | No | 126 | 0.131 | 107 | 13 | 0.121 | 0 |
| MIF4GD_ENST00000325102 | MIF4GD | A9UHW6 | MIF4G domain-containing protein | chr17 | GO:0045182 | Not Cancer Driver | No | 23 | 0.104 | 12 | 1 | 0.083 | 0 |
| MRPL58 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | chr17 | GO:0045182 | Not Cancer Driver | No | 28 | 0.136 | 105 | 13 | 0.124 | 0 |
| MTIF2_ENST00000403721 | MTIF2 | P46199 | Translation initiation factor IF-2, mitochondrial | chr2 | GO:0045182 | Not Cancer Driver | No | 101 | 0.139 | 112 | 9 | 0.08 | 0 |
| MTIF3_ENST00000381120 | MTIF3 | Q9H2K0 | Translation initiation factor IF-3, mitochondrial | chr13 | GO:0045182 | Not Cancer Driver | No | 26 | 0.094 | 180 | 19 | 0.106 | 0 |
| MTRF1 | MTRF1 | O75570 | Peptide chain release factor 1, mitochondrial | chr13 | GO:0045182 | Not Cancer Driver | No | 50 | 0.112 | 71 | 9 | 0.127 | 0 |
| MTRF1L | MTRF1L | Q9UGC7 | Peptide chain release factor 1-like, mitochondrial | chr6 | GO:0045182 | Not Cancer Driver | No | 31 | 0.082 | 183 | 12 | 0.066 | 0 |
| NANOS1 | NANOS1 | Q8WY41 | Nanos homolog 1 | chr10 | GO:0045182 | Not Cancer Driver | No | 7 | 0.024 | 169 | 2 | 0.012 | 0 |
| NEURL1 | NEURL1 | O76050 | E3 ubiquitin-protein ligase NEURL1 | chr10 | GO:0045182 | Not Cancer Driver | No | 62 | 0.108 | 153 | 11 | 0.072 | 0 |
| PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | GO:0045182 | Census, Compendium | Yes | 100 | 0.157 | 317 | 55 | 0.174 | 0 |
| PAIP1 | PAIP1 | Q9H074 | Polyadenylate-binding protein-interacting protein 1 | chr5 | GO:0045182 | Not Cancer Driver | No | 67 | 0.14 | 259 | 36 | 0.139 | 0 |
| PAIP2B | PAIP2B | Q9ULR5 | Polyadenylate-binding protein-interacting protein 2B | chr2 | GO:0045182 | Not Cancer Driver | No | 16 | 0.13 | 123 | 16 | 0.13 | 0 |
| PAIP2_ENST00000265192 | PAIP2 | Q9BPZ3 | Polyadenylate-binding protein-interacting protein 2 | chr5 | GO:0045182 | Not Cancer Driver | No | 11 | 0.087 | 88 | 10 | 0.114 | 0 |
| PKP3 | PKP3 | Q9Y446 | Plakophilin-3 | chr11 | GO:0045182 | Not Cancer Driver | No | 72 | 0.09 | 357 | 22 | 0.062 | 0 |
| PURA | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0045182 | Not Cancer Driver | No | 22 | 0.068 | 188 | 10 | 0.053 | 6 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0045182 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RPL10_ENST00000369817 | RPL10 | P27635 | 60S ribosomal protein L10 | chrX | GO:0045182 | Census, Compendium | Yes | 46 | 0.215 | 9 | 3 | 0.333 | 4 |
| RPL22 | RPL22 | P35268 | 60S ribosomal protein L22 | chr1 | GO:0045182 | Census, Compendium | Yes | 26 | 0.203 | 15 | 1 | 0.067 | 0 |
| RPS14_ENST00000521466 | RPS14 | P62263 | 40S ribosomal protein S14 | chr5 | GO:0045182 | Not Cancer Driver | No | 14 | 0.093 | 96 | 13 | 0.135 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0045182 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| RPS9_ENST00000391752 | RPS9 | P46781 | 40S ribosomal protein S9 | chr19 | GO:0045182 | Not Cancer Driver | No | 23 | 0.119 | 34 | 5 | 0.147 | 0 |
| SAMD4A | SAMD4A | Q9UPU9 | Protein Smaug homolog 1 | chr14 | GO:0045182 | Not Cancer Driver | No | 83 | 0.116 | 473 | 55 | 0.116 | 0 |
| SAMD4B | SAMD4B | Q5PRF9 | Protein Smaug homolog 2 | chr19 | GO:0045182 | Not Cancer Driver | No | 79 | 0.114 | 467 | 57 | 0.122 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | GO:0045182 | Not Cancer Driver | No | 51 | 0.106 | 32 | 7 | 0.219 | 0 |
| SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | GO:0045182 | Not Cancer Driver | No | 57 | 0.113 | 58 | 5 | 0.086 | 1 |
| TRIM71 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0045182 | Not Cancer Driver | No | 124 | 0.143 | 163 | 21 | 0.129 | 2 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | GO:0045182 | Not Cancer Driver | No | 37 | 0.114 | 74 | 7 | 0.095 | 2 |
| TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | GO:0045182 | Not Cancer Driver | No | 51 | 0.113 | 50 | 3 | 0.06 | 1 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0045182 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| ZCCHC13 | ZCCHC13 | Q8WW36 | Zinc finger CCHC domain-containing protein 13 | chrX | GO:0045182 | Not Cancer Driver | No | 44 | 0.265 | 13 | 5 | 0.385 | 0 |
| ZNF540_ENST00000316433 | ZNF540 | Q8NDQ6 | Zinc finger protein 540 | chr19 | GO:0045182 | Not Cancer Driver | No | 103 | 0.156 | 87 | 14 | 0.161 | 0 |