Total number of protein in "GO:0045177" GO term: 67
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0045177 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| ADGRF5_ENST00000265417 | ADGRF5 | Q8IZF2 | Adhesion G protein-coupled receptor F5 | chr6 | GO:0045177 | Not Cancer Driver | No | 255 | 0.189 | 53 | 11 | 0.208 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0045177 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0045177 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| AQP8 | AQP8 | O94778 | Aquaporin-8 | chr16 | GO:0045177 | Not Cancer Driver | No | 49 | 0.188 | 0 | 0 | 0.0 | 0 |
| ATP6V0A4 | ATP6V0A4 | Q9HBG4 | V-type proton ATPase 116 kDa subunit a 4 | chr7 | GO:0045177 | Not Cancer Driver | No | 148 | 0.176 | 43 | 6 | 0.14 | 6 |
| ATP6V1C1_ENST00000518738 | ATP6V1C1 | P21283 | V-type proton ATPase subunit C 1 | chr8 | GO:0045177 | Not Cancer Driver | No | 54 | 0.141 | 17 | 3 | 0.176 | 0 |
| BYSL | BYSL | Q13895 | Bystin | chr6 | GO:0045177 | Not Cancer Driver | No | 38 | 0.087 | 176 | 14 | 0.08 | 0 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0045177 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| C5AR2_ENST00000600626 | C5AR2 | Q9P296 | C5a anaphylatoxin chemotactic receptor 2 | chr19 | GO:0045177 | Not Cancer Driver | No | 60 | 0.178 | 11 | 3 | 0.273 | 0 |
| CA2 | CA2 | P00918 | Carbonic anhydrase 2 | chr8 | GO:0045177 | Not Cancer Driver | No | 41 | 0.158 | 55 | 8 | 0.145 | 4 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0045177 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0045177 | Not Cancer Driver | No | 238 | 0.263 | 461 | 130 | 0.282 | 7 |
| CETN2 | CETN2 | P41208 | Centrin-2 | chrX | GO:0045177 | Not Cancer Driver | No | 33 | 0.192 | 97 | 11 | 0.113 | 0 |
| CHL1_ENST00000397491 | CHL1 | O00533 | Neural cell adhesion molecule L1-like protein | chr3 | GO:0045177 | Not Cancer Driver | No | 348 | 0.288 | 415 | 121 | 0.292 | 0 |
| CLCN5 | CLCN5 | P51795 | H(+)/Cl(-) exchange transporter 5 | chrX | GO:0045177 | Not Cancer Driver | No | 138 | 0.169 | 81 | 6 | 0.074 | 32 |
| CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | GO:0045177 | Not Cancer Driver | No | 24 | 0.095 | 49 | 4 | 0.082 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0045177 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| DCHS1 | DCHS1 | Q96JQ0 | Protocadherin-16 | chr11 | GO:0045177 | Not Cancer Driver | No | 444 | 0.135 | 2197 | 317 | 0.144 | 3 |
| DPEP1 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0045177 | Not Cancer Driver | No | 54 | 0.131 | 41 | 6 | 0.146 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0045177 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| DUOX2 | DUOX2 | Q9NRD8 | Dual oxidase 2 | chr15 | GO:0045177 | Not Cancer Driver | No | 245 | 0.158 | 182 | 25 | 0.137 | 3 |
| DUOXA2 | DUOXA2 | Q1HG44 | Dual oxidase maturation factor 2 | chr15 | GO:0045177 | Not Cancer Driver | No | 40 | 0.125 | 0 | 0 | 0.0 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0045177 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DYNC2H1_ENST00000375735 | DYNC2H1 | Q8NCM8 | Cytoplasmic dynein 2 heavy chain 1 | chr11 | GO:0045177 | Not Cancer Driver | No | 510 | 0.118 | 282 | 15 | 0.053 | 34 |
| DYNC2LI1_ENST00000260605 | DYNC2LI1 | Q8TCX1 | Cytoplasmic dynein 2 light intermediate chain 1 | chr2 | GO:0045177 | Not Cancer Driver | No | 53 | 0.151 | 93 | 8 | 0.086 | 2 |
| EDA | EDA | Q92838 | Ectodysplasin-A | chrX | GO:0045177 | Not Cancer Driver | No | 73 | 0.187 | 243 | 43 | 0.177 | 71 |
| EDAR | EDAR | Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | chr2 | GO:0045177 | Not Cancer Driver | No | 81 | 0.181 | 116 | 20 | 0.172 | 18 |
| EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0045177 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
| ENPEP | ENPEP | Q07075 | Glutamyl aminopeptidase | chr4 | GO:0045177 | Compendium | Yes | 235 | 0.246 | 130 | 44 | 0.338 | 0 |
| EPB41L4B | EPB41L4B | Q9H329 | Band 4.1-like protein 4B | chr9 | GO:0045177 | Not Cancer Driver | No | 131 | 0.146 | 548 | 77 | 0.141 | 0 |
| EZR | EZR | P15311 | Ezrin | chr6 | GO:0045177 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
| FAP | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0045177 | Not Cancer Driver | No | 158 | 0.208 | 6 | 2 | 0.333 | 0 |
| HFE | HFE | Q30201 | Hereditary hemochromatosis protein | chr6 | GO:0045177 | Not Cancer Driver | No | 55 | 0.158 | 27 | 2 | 0.074 | 11 |
| HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | GO:0045177 | Not Cancer Driver | No | 46 | 0.13 | 243 | 32 | 0.132 | 0 |
| HOMER2 | HOMER2 | Q9NSB8 | Homer protein homolog 2 | chr15 | GO:0045177 | Not Cancer Driver | No | 53 | 0.15 | 233 | 32 | 0.137 | 1 |
| IFIT5 | IFIT5 | Q13325 | Interferon-induced protein with tetratricopeptide repeats 5 | chr10 | GO:0045177 | Not Cancer Driver | No | 43 | 0.089 | 19 | 0 | 0.0 | 0 |
| ITGA8 | ITGA8 | P53708 | Integrin alpha-8 | chr10 | GO:0045177 | Not Cancer Driver | No | 292 | 0.275 | 114 | 26 | 0.228 | 1 |
| ITPR3 | ITPR3 | Q14573 | Inositol 1,4,5-trisphosphate receptor type 3 | chr6 | GO:0045177 | Not Cancer Driver | No | 336 | 0.126 | 385 | 44 | 0.114 | 0 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0045177 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LGMN_ENST00000334869 | LGMN | Q99538 | Legumain | chr14 | GO:0045177 | Not Cancer Driver | No | 57 | 0.132 | 112 | 19 | 0.17 | 0 |
| MPDZ | MPDZ | O75970 | Multiple PDZ domain protein | chr9 | GO:0045177 | Not Cancer Driver | No | 287 | 0.139 | 858 | 122 | 0.142 | 0 |
| MSN | MSN | P26038 | Moesin | chrX | GO:0045177 | Census, Compendium | Yes | 108 | 0.187 | 286 | 56 | 0.196 | 1 |
| MYL12B_ENST00000237500 | MYL12B | O14950 | Myosin regulatory light chain 12B | chr18 | GO:0045177 | Not Cancer Driver | No | 23 | 0.134 | 61 | 13 | 0.213 | 0 |
| MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | GO:0045177 | Not Cancer Driver | No | 144 | 0.127 | 34 | 4 | 0.118 | 0 |
| NEDD1_ENST00000266742 | NEDD1 | Q8NHV4 | Protein NEDD1 | chr12 | GO:0045177 | Not Cancer Driver | No | 87 | 0.132 | 282 | 36 | 0.128 | 0 |
| NF2 | NF2 | P35240 | Merlin | chr22 | GO:0045177 | Census, Compendium | Yes | 69 | 0.116 | 252 | 26 | 0.103 | 16 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0045177 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
| NUMB_ENST00000355058 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0045177 | Not Cancer Driver | No | 70 | 0.108 | 490 | 58 | 0.118 | 0 |
| PATJ | PATJ | Q8NI35 | InaD-like protein | chr1 | GO:0045177 | Not Cancer Driver | No | 261 | 0.145 | 918 | 142 | 0.155 | 0 |
| PCM1 | PCM1 | Q15154 | Pericentriolar material 1 protein | chr8 | GO:0045177 | Census | Yes | 152 | 0.075 | 1665 | 134 | 0.08 | 0 |
| PDZD3_ENST00000531114 | PDZD3 | Q86UT5 | Na(+)/H(+) exchange regulatory cofactor NHE-RF4 | chr11 | GO:0045177 | Not Cancer Driver | No | 58 | 0.102 | 199 | 19 | 0.095 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0045177 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0045177 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | GO:0045177 | Not Cancer Driver | No | 71 | 0.122 | 297 | 37 | 0.125 | 1 |
| REN | REN | P00797 | Renin | chr1 | GO:0045177 | Not Cancer Driver | No | 60 | 0.148 | 10 | 0 | 0.0 | 3 |
| SIPA1L3 | SIPA1L3 | O60292 | Signal-induced proliferation-associated 1-like protein 3 | chr19 | GO:0045177 | Not Cancer Driver | No | 273 | 0.153 | 1257 | 190 | 0.151 | 0 |
| SLC11A2_ENST00000262051 | SLC11A2 | P49281 | Natural resistance-associated macrophage protein 2 | chr12 | GO:0045177 | Not Cancer Driver | No | 60 | 0.106 | 38 | 5 | 0.132 | 3 |
| SLC4A9 | SLC4A9 | Q96Q91 | Anion exchange protein 4 | chr5 | GO:0045177 | Not Cancer Driver | No | 98 | 0.1 | 208 | 20 | 0.096 | 0 |
| SLC7A11 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0045177 | Not Cancer Driver | No | 70 | 0.14 | 15 | 2 | 0.133 | 0 |
| SRR | SRR | Q9GZT4 | Serine racemase | chr17 | GO:0045177 | Not Cancer Driver | No | 40 | 0.118 | 32 | 6 | 0.188 | 0 |
| SVBP_ENST00000372522 | SVBP | Q8N300 | Small vasohibin-binding protein | chr1 | GO:0045177 | Not Cancer Driver | No | 7 | 0.106 | 66 | 7 | 0.106 | 0 |
| TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | GO:0045177 | Not Cancer Driver | No | 198 | 0.113 | 1350 | 151 | 0.112 | 0 |
| TUBG1 | TUBG1 | P23258 | Tubulin gamma-1 chain | chr17 | GO:0045177 | Not Cancer Driver | No | 51 | 0.113 | 44 | 10 | 0.227 | 3 |
| USH1C_ENST00000318024 | USH1C | Q9Y6N9 | Harmonin | chr11 | GO:0045177 | Not Cancer Driver | No | 118 | 0.214 | 153 | 45 | 0.294 | 0 |
| VASH1 | VASH1 | Q7L8A9 | Tubulinyl-Tyr carboxypeptidase 1 | chr14 | GO:0045177 | Not Cancer Driver | No | 39 | 0.107 | 215 | 18 | 0.084 | 0 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | GO:0045177 | Not Cancer Driver | No | 188 | 0.254 | 110 | 28 | 0.255 | 0 |