Total number of protein in "GO:0044853" GO term: 104
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0044853 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| ADCYAP1R1_ENST00000304166 | ADCYAP1R1 | P41586 | Pituitary adenylate cyclase-activating polypeptide type I receptor | chr7 | GO:0044853 | Not Cancer Driver | No | 127 | 0.271 | 0 | 0 | 0.0 | 0 |
| ADD2_ENST00000407644 | ADD2 | P35612 | Beta-adducin | chr2 | GO:0044853 | Not Cancer Driver | No | 157 | 0.216 | 423 | 104 | 0.246 | 0 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0044853 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| ADRA1B | ADRA1B | P35368 | Alpha-1B adrenergic receptor | chr5 | GO:0044853 | Not Cancer Driver | No | 53 | 0.102 | 132 | 1 | 0.008 | 0 |
| ADTRP_ENST00000414691 | ADTRP | Q96IZ2 | Androgen-dependent TFPI-regulating protein | chr6 | GO:0044853 | Not Cancer Driver | No | 41 | 0.178 | 2 | 0 | 0.0 | 0 |
| AKAP6 | AKAP6 | Q13023 | A-kinase anchor protein 6 | chr14 | GO:0044853 | Not Cancer Driver | No | 383 | 0.165 | 1456 | 240 | 0.165 | 0 |
| ASAH2 | ASAH2 | Q9NR71 | Neutral ceramidase | chr10 | GO:0044853 | Not Cancer Driver | No | 71 | 0.091 | 140 | 24 | 0.171 | 0 |
| ATP1A2 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0044853 | Not Cancer Driver | No | 230 | 0.225 | 161 | 34 | 0.211 | 8 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | GO:0044853 | Not Cancer Driver | No | 38 | 0.125 | 55 | 9 | 0.164 | 0 |
| BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0044853 | Census, Compendium | Yes | 66 | 0.124 | 21 | 0 | 0.0 | 8 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0044853 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| BVES | BVES | Q8NE79 | Blood vessel epicardial substance | chr6 | GO:0044853 | Not Cancer Driver | No | 59 | 0.164 | 65 | 15 | 0.231 | 1 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0044853 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0044853 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0044853 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CAVIN1 | CAVIN1 | Q6NZI2 | Caveolae-associated protein 1 | chr17 | GO:0044853 | Not Cancer Driver | No | 66 | 0.169 | 280 | 50 | 0.179 | 0 |
| CAVIN2 | CAVIN2 | O95810 | Caveolae-associated protein 2 | chr2 | GO:0044853 | Not Cancer Driver | No | 109 | 0.256 | 393 | 99 | 0.252 | 0 |
| CAVIN3 | CAVIN3 | Q969G5 | Caveolae-associated protein 3 | chr11 | GO:0044853 | Not Cancer Driver | No | 22 | 0.084 | 234 | 19 | 0.081 | 0 |
| CAVIN4 | CAVIN4 | Q5BKX8 | Caveolae-associated protein 4 | chr9 | GO:0044853 | Not Cancer Driver | No | 59 | 0.162 | 286 | 45 | 0.157 | 0 |
| CD177 | CD177 | Q8N6Q3 | CD177 antigen | chr19 | GO:0044853 | Not Cancer Driver | No | 71 | 0.162 | 79 | 26 | 0.329 | 0 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0044853 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CD8A_ENST00000283635 | CD8A | P01732 | T-cell surface glycoprotein CD8 alpha chain | chr2 | GO:0044853 | Not Cancer Driver | No | 33 | 0.14 | 28 | 2 | 0.071 | 1 |
| CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0044853 | Not Cancer Driver | No | 168 | 0.236 | 235 | 59 | 0.251 | 0 |
| CDH15 | CDH15 | P55291 | Cadherin-15 | chr16 | GO:0044853 | Not Cancer Driver | No | 105 | 0.129 | 405 | 57 | 0.141 | 3 |
| CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0044853 | Not Cancer Driver | No | 238 | 0.263 | 461 | 130 | 0.282 | 7 |
| CHRNA3 | CHRNA3 | P32297 | Neuronal acetylcholine receptor subunit alpha-3 | chr15 | GO:0044853 | Not Cancer Driver | No | 86 | 0.17 | 11 | 1 | 0.091 | 0 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0044853 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CHRNB2 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0044853 | Not Cancer Driver | No | 92 | 0.183 | 23 | 2 | 0.087 | 2 |
| CLN3_ENST00000636147 | CLN3 | Q13286 | Battenin | chr16 | GO:0044853 | Not Cancer Driver | No | 58 | 0.132 | 69 | 10 | 0.145 | 9 |
| CR1_ENST00000367053 | CR1 | P17927 | Complement receptor type 1 | chr1 | GO:0044853 | Compendium | Yes | 383 | 0.188 | 151 | 42 | 0.278 | 0 |
| DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0044853 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
| DLC1 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0044853 | Not Cancer Driver | No | 331 | 0.217 | 922 | 237 | 0.257 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0044853 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| EHD2 | EHD2 | Q9NZN4 | EH domain-containing protein 2 | chr19 | GO:0044853 | Compendium | Yes | 85 | 0.157 | 125 | 12 | 0.096 | 0 |
| EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0044853 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
| EZR | EZR | P15311 | Ezrin | chr6 | GO:0044853 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0044853 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| FASLG | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0044853 | Not Cancer Driver | No | 65 | 0.231 | 94 | 18 | 0.191 | 1 |
| FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | GO:0044853 | Not Cancer Driver | No | 43 | 0.101 | 122 | 15 | 0.123 | 0 |
| FLOT2 | FLOT2 | Q14254 | Flotillin-2 | chr17 | GO:0044853 | Not Cancer Driver | No | 56 | 0.131 | 20 | 3 | 0.15 | 0 |
| FXYD1_ENST00000455515 | FXYD1 | O00168 | Phospholemman | chr19 | GO:0044853 | Not Cancer Driver | No | 10 | 0.109 | 22 | 4 | 0.182 | 0 |
| GASK1A | GASK1A | Q9UFP1 | Golgi-associated kinase 1A | chr3 | GO:0044853 | Not Cancer Driver | No | 25 | 0.043 | 235 | 10 | 0.043 | 0 |
| HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0044853 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0044853 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0044853 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0044853 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0044853 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0044853 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0044853 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0044853 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| ITGAM_ENST00000287497 | ITGAM | P11215 | Integrin alpha-M | chr16 | GO:0044853 | Not Cancer Driver | No | 191 | 0.166 | 133 | 12 | 0.09 | 0 |
| ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | GO:0044853 | Not Cancer Driver | No | 147 | 0.191 | 59 | 9 | 0.153 | 15 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0044853 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:0044853 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KCND2 | KCND2 | Q9NZV8 | Potassium voltage-gated channel subfamily D member 2 | chr7 | GO:0044853 | Not Cancer Driver | No | 220 | 0.349 | 195 | 62 | 0.318 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | GO:0044853 | Not Cancer Driver | No | 222 | 0.18 | 225 | 39 | 0.173 | 5 |
| KIF18A | KIF18A | Q8NI77 | Kinesin-like protein KIF18A | chr11 | GO:0044853 | Not Cancer Driver | No | 114 | 0.127 | 405 | 60 | 0.148 | 0 |
| LCP2 | LCP2 | Q13094 | Lymphocyte cytosolic protein 2 | chr5 | GO:0044853 | Not Cancer Driver | No | 107 | 0.201 | 390 | 80 | 0.205 | 0 |
| LIPE | LIPE | Q05469 | Hormone-sensitive lipase | chr19 | GO:0044853 | Not Cancer Driver | No | 123 | 0.114 | 496 | 65 | 0.131 | 0 |
| LRP4 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 | chr11 | GO:0044853 | Not Cancer Driver | No | 233 | 0.122 | 265 | 28 | 0.106 | 11 |
| LRP6 | LRP6 | O75581 | Low-density lipoprotein receptor-related protein 6 | chr12 | GO:0044853 | Not Cancer Driver | No | 206 | 0.128 | 255 | 30 | 0.118 | 5 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0044853 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| LYPD4 | LYPD4 | Q6UWN0 | Ly6/PLAUR domain-containing protein 4 | chr19 | GO:0044853 | Not Cancer Driver | No | 44 | 0.179 | 0 | 0 | 0.0 | 0 |
| MAL | MAL | P21145 | Myelin and lymphocyte protein | chr2 | GO:0044853 | Not Cancer Driver | No | 21 | 0.137 | 0 | 0 | 0.0 | 0 |
| MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0044853 | Census, Compendium | Yes | 62 | 0.172 | 2 | 0 | 0.0 | 7 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0044853 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MLC1 | MLC1 | Q15049 | Membrane protein MLC1 | chr22 | GO:0044853 | Not Cancer Driver | No | 53 | 0.141 | 35 | 7 | 0.2 | 15 |
| MS4A1_ENST00000345732 | MS4A1 | P11836 | B-lymphocyte antigen CD20 | chr11 | GO:0044853 | Not Cancer Driver | No | 73 | 0.246 | 83 | 23 | 0.277 | 0 |
| MS4A4A | MS4A4A | Q96JQ5 | Membrane-spanning 4-domains subfamily A member 4A | chr11 | GO:0044853 | Not Cancer Driver | No | 56 | 0.234 | 38 | 6 | 0.158 | 0 |
| MYO1A | MYO1A | Q9UBC5 | Unconventional myosin-Ia | chr12 | GO:0044853 | Not Cancer Driver | No | 170 | 0.163 | 57 | 5 | 0.088 | 0 |
| MYOF | MYOF | Q9NZM1 | Myoferlin | chr10 | GO:0044853 | Not Cancer Driver | No | 269 | 0.131 | 401 | 55 | 0.137 | 0 |
| NOS1AP | NOS1AP | O75052 | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein | chr1 | GO:0044853 | Not Cancer Driver | No | 94 | 0.186 | 255 | 53 | 0.208 | 1 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0044853 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| ORAI1 | ORAI1 | Q96D31 | Calcium release-activated calcium channel protein 1 | chr12 | GO:0044853 | Not Cancer Driver | No | 26 | 0.086 | 101 | 9 | 0.089 | 5 |
| PACSIN2_ENST00000402229 | PACSIN2 | Q9UNF0 | Protein kinase C and casein kinase substrate in neurons protein 2 | chr22 | GO:0044853 | Not Cancer Driver | No | 51 | 0.105 | 301 | 27 | 0.09 | 0 |
| PLPP1_ENST00000307259 | PLPP1 | O14494 | Phospholipid phosphatase 1 | chr5 | GO:0044853 | Not Cancer Driver | No | 28 | 0.099 | 27 | 1 | 0.037 | 0 |
| PLPP2_ENST00000434325 | PLPP2 | O43688 | Phospholipid phosphatase 2 | chr19 | GO:0044853 | Not Cancer Driver | No | 47 | 0.163 | 0 | 0 | 0.0 | 0 |
| PLVAP | PLVAP | Q9BX97 | Plasmalemma vesicle-associated protein | chr19 | GO:0044853 | Not Cancer Driver | No | 96 | 0.217 | 174 | 39 | 0.224 | 1 |
| PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | GO:0044853 | Census | Yes | 53 | 0.151 | 24 | 0 | 0.0 | 2 |
| PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | GO:0044853 | Census, Compendium | Yes | 39 | 0.102 | 66 | 11 | 0.167 | 17 |
| PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | GO:0044853 | Not Cancer Driver | No | 37 | 0.092 | 149 | 13 | 0.087 | 0 |
| PRTN3 | PRTN3 | P24158 | Myeloblastin | chr19 | GO:0044853 | Not Cancer Driver | No | 20 | 0.078 | 46 | 1 | 0.022 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0044853 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0044853 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0044853 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| RANGRF | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0044853 | Not Cancer Driver | No | 10 | 0.054 | 42 | 5 | 0.119 | 0 |
| SCARB1_ENST00000415380 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0044853 | Not Cancer Driver | No | 53 | 0.096 | 6 | 1 | 0.167 | 0 |
| SCN5A_ENST00000333535 | SCN5A | Q14524 | Sodium channel protein type 5 subunit alpha | chr3 | GO:0044853 | Not Cancer Driver | No | 491 | 0.244 | 550 | 144 | 0.262 | 190 |
| SELE | SELE | P16581 | E-selectin | chr1 | GO:0044853 | Not Cancer Driver | No | 137 | 0.225 | 12 | 0 | 0.0 | 0 |
| SELPLG_ENST00000550948 | SELPLG | Q14242 | P-selectin glycoprotein ligand 1 | chr12 | GO:0044853 | Not Cancer Driver | No | 68 | 0.165 | 297 | 48 | 0.162 | 0 |
| SKAP1_ENST00000584924 | SKAP1 | Q86WV1 | Src kinase-associated phosphoprotein 1 | chr17 | GO:0044853 | Not Cancer Driver | No | 67 | 0.187 | 130 | 27 | 0.208 | 0 |
| SLC22A6 | SLC22A6 | Q4U2R8 | Solute carrier family 22 member 6 | chr11 | GO:0044853 | Not Cancer Driver | No | 85 | 0.151 | 72 | 11 | 0.153 | 0 |
| SLC2A1 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | GO:0044853 | Not Cancer Driver | No | 51 | 0.104 | 13 | 2 | 0.154 | 48 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0044853 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SMPD2 | SMPD2 | O60906 | Sphingomyelin phosphodiesterase 2 | chr6 | GO:0044853 | Not Cancer Driver | No | 45 | 0.106 | 48 | 5 | 0.104 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0044853 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0044853 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | GO:0044853 | Not Cancer Driver | No | 70 | 0.102 | 387 | 45 | 0.116 | 13 |
| TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | GO:0044853 | Not Cancer Driver | No | 45 | 0.181 | 2 | 0 | 0.0 | 0 |
| TFPI | TFPI | P10646 | Tissue factor pathway inhibitor | chr2 | GO:0044853 | Not Cancer Driver | No | 47 | 0.155 | 28 | 2 | 0.071 | 0 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0044853 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0044853 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRPC4_ENST00000379705 | TRPC4 | Q9UBN4 | Short transient receptor potential channel 4 | chr13 | GO:0044853 | Not Cancer Driver | No | 322 | 0.33 | 195 | 66 | 0.338 | 0 |