Total number of protein in "GO:0044297" GO term: 69
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | GO:0044297 | Not Cancer Driver | No | 70 | 0.186 | 48 | 14 | 0.292 | 84 |
| ACTA2 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | GO:0044297 | Not Cancer Driver | No | 50 | 0.133 | 39 | 4 | 0.103 | 17 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | GO:0044297 | Not Cancer Driver | No | 114 | 0.302 | 48 | 19 | 0.396 | 11 |
| ACTG2_ENST00000345517 | ACTG2 | P63267 | Actin, gamma-enteric smooth muscle | chr2 | GO:0044297 | Not Cancer Driver | No | 80 | 0.213 | 39 | 8 | 0.205 | 21 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | GO:0044297 | Not Cancer Driver | No | 56 | 0.16 | 0 | 0 | 0.0 | 2 |
| CACNG4 | CACNG4 | Q9UBN1 | Voltage-dependent calcium channel gamma-4 subunit | chr17 | GO:0044297 | Not Cancer Driver | No | 51 | 0.156 | 71 | 17 | 0.239 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0044297 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | GO:0044297 | Not Cancer Driver | No | 63 | 0.118 | 46 | 3 | 0.065 | 0 |
| CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | GO:0044297 | Not Cancer Driver | No | 71 | 0.13 | 95 | 12 | 0.126 | 0 |
| CCT4 | CCT4 | P50991 | T-complex protein 1 subunit delta | chr2 | GO:0044297 | Not Cancer Driver | No | 51 | 0.095 | 92 | 2 | 0.022 | 0 |
| CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | GO:0044297 | Not Cancer Driver | No | 83 | 0.153 | 72 | 10 | 0.139 | 1 |
| CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | GO:0044297 | Not Cancer Driver | No | 59 | 0.109 | 36 | 6 | 0.167 | 0 |
| CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | GO:0044297 | Not Cancer Driver | No | 41 | 0.075 | 36 | 2 | 0.056 | 0 |
| CD200_ENST00000315711 | CD200 | P41217 | OX-2 membrane glycoprotein | chr3 | GO:0044297 | Not Cancer Driver | No | 37 | 0.133 | 14 | 0 | 0.0 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0044297 | Not Cancer Driver | No | 28 | 0.135 | 72 | 12 | 0.167 | 0 |
| CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | GO:0044297 | Not Cancer Driver | No | 51 | 0.14 | 98 | 19 | 0.194 | 0 |
| CXorf56_ENST00000644802 | STEEP1 | Q9H5V9 | STING ER exit protein | chrX | GO:0044297 | Not Cancer Driver | No | 44 | 0.198 | 115 | 32 | 0.278 | 0 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | GO:0044297 | Not Cancer Driver | No | 132 | 0.155 | 514 | 82 | 0.16 | 0 |
| DPYSL3_ENST00000398514 | DPYSL3 | Q14195 | Dihydropyrimidinase-related protein 3 | chr5 | GO:0044297 | Not Cancer Driver | No | 93 | 0.163 | 128 | 14 | 0.109 | 0 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0044297 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| EVX1 | EVX1 | P49640 | Homeobox even-skipped homolog protein 1 | chr7 | GO:0044297 | Not Cancer Driver | No | 37 | 0.091 | 227 | 19 | 0.084 | 0 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0044297 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0044297 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0044297 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | GO:0044297 | Not Cancer Driver | No | 65 | 0.15 | 288 | 42 | 0.146 | 62 |
| GJB2_ENST00000382848 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0044297 | Not Cancer Driver | No | 34 | 0.15 | 0 | 0 | 0.0 | 46 |
| GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | GO:0044297 | Compendium | Yes | 50 | 0.141 | 24 | 0 | 0.0 | 0 |
| GNAZ | GNAZ | P19086 | Guanine nucleotide-binding protein G(z) subunit alpha | chr22 | GO:0044297 | Not Cancer Driver | No | 84 | 0.237 | 30 | 13 | 0.433 | 0 |
| GNB3 | GNB3 | P16520 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | chr12 | GO:0044297 | Not Cancer Driver | No | 51 | 0.15 | 13 | 1 | 0.077 | 0 |
| GNB4_ENST00000468623 | GNB4 | Q9HAV0 | Guanine nucleotide-binding protein subunit beta-4 | chr3 | GO:0044297 | Not Cancer Driver | No | 49 | 0.144 | 27 | 3 | 0.111 | 2 |
| GNG3 | GNG3 | P63215 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | chr11 | GO:0044297 | Not Cancer Driver | No | 10 | 0.133 | 20 | 1 | 0.05 | 0 |
| HSPA1L | HSPA1L | P34931 | Heat shock 70 kDa protein 1-like | chr6 | GO:0044297 | Not Cancer Driver | No | 119 | 0.186 | 141 | 28 | 0.199 | 0 |
| KCNJ10 | KCNJ10 | P78508 | ATP-sensitive inward rectifier potassium channel 10 | chr1 | GO:0044297 | Not Cancer Driver | No | 78 | 0.206 | 28 | 10 | 0.357 | 8 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0044297 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MAPK8IP3_ENST00000250894 | MAPK8IP3 | Q9UPT6 | C-Jun-amino-terminal kinase-interacting protein 3 | chr16 | GO:0044297 | Not Cancer Driver | No | 179 | 0.134 | 746 | 110 | 0.147 | 3 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0044297 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| NAXE | NAXE | Q8NCW5 | NAD(P)H-hydrate epimerase | chr1 | GO:0044297 | Not Cancer Driver | No | 22 | 0.076 | 5 | 0 | 0.0 | 2 |
| NF2 | NF2 | P35240 | Merlin | chr22 | GO:0044297 | Census, Compendium | Yes | 69 | 0.116 | 252 | 26 | 0.103 | 16 |
| P2RX4_ENST00000337233 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0044297 | Not Cancer Driver | No | 36 | 0.093 | 0 | 0 | 0.0 | 0 |
| P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | GO:0044297 | Not Cancer Driver | No | 60 | 0.161 | 16 | 1 | 0.062 | 0 |
| PACRG | PACRG | Q96M98 | Parkin coregulated gene protein | chr6 | GO:0044297 | Not Cancer Driver | No | 66 | 0.223 | 45 | 6 | 0.133 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0044297 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PGRMC1 | PGRMC1 | O00264 | Membrane-associated progesterone receptor component 1 | chrX | GO:0044297 | Not Cancer Driver | No | 30 | 0.154 | 74 | 16 | 0.216 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0044297 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PITPNM1_ENST00000534749 | PITPNM1 | O00562 | Membrane-associated phosphatidylinositol transfer protein 1 | chr11 | GO:0044297 | Not Cancer Driver | No | 157 | 0.126 | 477 | 69 | 0.145 | 0 |
| PITPNM3 | PITPNM3 | Q9BZ71 | Membrane-associated phosphatidylinositol transfer protein 3 | chr17 | GO:0044297 | Not Cancer Driver | No | 143 | 0.147 | 334 | 53 | 0.159 | 1 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0044297 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTPN13_ENST00000411767 | PTPN13 | Q12923 | Tyrosine-protein phosphatase non-receptor type 13 | chr4 | GO:0044297 | Census, Compendium | Yes | 299 | 0.12 | 1231 | 149 | 0.121 | 0 |
| RDH5_ENST00000548082 | RDH5 | Q92781 | Retinol dehydrogenase 5 | chr12 | GO:0044297 | Not Cancer Driver | No | 39 | 0.123 | 0 | 0 | 0.0 | 18 |
| RIT2 | RIT2 | Q99578 | GTP-binding protein Rit2 | chr18 | GO:0044297 | Not Cancer Driver | No | 74 | 0.341 | 29 | 11 | 0.379 | 0 |
| RLBP1 | RLBP1 | P12271 | Retinaldehyde-binding protein 1 | chr15 | GO:0044297 | Not Cancer Driver | No | 53 | 0.167 | 71 | 16 | 0.225 | 3 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0044297 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| RNF157 | RNF157 | Q96PX1 | E3 ubiquitin ligase RNF157 | chr17 | GO:0044297 | Not Cancer Driver | No | 76 | 0.112 | 375 | 39 | 0.104 | 0 |
| RPE65 | RPE65 | Q16518 | Retinoid isomerohydrolase | chr1 | GO:0044297 | Not Cancer Driver | No | 109 | 0.205 | 10 | 1 | 0.1 | 44 |
| RPL28_ENST00000559463 | RPL28 | P46779 | 60S ribosomal protein L28 | chr19 | GO:0044297 | Not Cancer Driver | No | 29 | 0.212 | 115 | 24 | 0.209 | 0 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | GO:0044297 | Not Cancer Driver | No | 38 | 0.153 | 150 | 25 | 0.167 | 0 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | GO:0044297 | Not Cancer Driver | No | 141 | 0.116 | 297 | 18 | 0.061 | 8 |
| SLC1A2 | SLC1A2 | P43004 | Excitatory amino acid transporter 2 | chr11 | GO:0044297 | Not Cancer Driver | No | 77 | 0.134 | 81 | 7 | 0.086 | 3 |
| SLC2A13 | SLC2A13 | Q96QE2 | Proton myo-inositol cotransporter | chr12 | GO:0044297 | Not Cancer Driver | No | 79 | 0.122 | 52 | 4 | 0.077 | 0 |
| STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | GO:0044297 | Not Cancer Driver | No | 77 | 0.133 | 456 | 63 | 0.138 | 0 |
| SYNDIG1 | SYNDIG1 | Q9H7V2 | Synapse differentiation-inducing gene protein 1 | chr20 | GO:0044297 | Not Cancer Driver | No | 90 | 0.349 | 110 | 40 | 0.364 | 0 |
| TACR1 | TACR1 | P25103 | Substance-P receptor | chr2 | GO:0044297 | Not Cancer Driver | No | 69 | 0.17 | 28 | 2 | 0.071 | 0 |
| TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | GO:0044297 | Not Cancer Driver | No | 54 | 0.097 | 55 | 10 | 0.182 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0044297 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TMEM132E | TMEM132E | Q6IEE7 | Transmembrane protein 132E | chr17 | GO:0044297 | Not Cancer Driver | No | 189 | 0.176 | 500 | 73 | 0.146 | 1 |
| TRPV2 | TRPV2 | Q9Y5S1 | Transient receptor potential cation channel subfamily V member 2 | chr17 | GO:0044297 | Not Cancer Driver | No | 105 | 0.137 | 175 | 23 | 0.131 | 0 |
| TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | GO:0044297 | Not Cancer Driver | No | 40 | 0.09 | 63 | 11 | 0.175 | 5 |
| USP33_ENST00000357428 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | GO:0044297 | Not Cancer Driver | No | 138 | 0.146 | 256 | 48 | 0.188 | 0 |
| ZPBP2 | ZPBP2 | Q6X784 | Zona pellucida-binding protein 2 | chr17 | GO:0044297 | Not Cancer Driver | No | 47 | 0.139 | 7 | 1 | 0.143 | 0 |