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Total number of protein in "GO:0044271" GO term:  516

Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
GO term
Database
Cancer Driver
Number of missense mutations
Missense mutation per residues
Number of disordered residues
Number of mutations in disordered regions
Disordered missense mutations per residues
Number of OMIM mutation
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0044271 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0044271 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA8 ABCA8 O94911 ABC-type organic anion transporter ABCA8 chr17 GO:0044271 Not Cancer Driver No 290 0.179 91 20 0.22 0
ABCB6 ABCB6 Q9NP58 ATP-binding cassette sub-family B member 6 chr2 GO:0044271 Not Cancer Driver No 87 0.103 27 1 0.037 11
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0044271 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0044271 Not Cancer Driver No 61 0.145 41 5 0.122 19
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0044271 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACER1 ACER1 Q8TDN7 Alkaline ceramidase 1 chr19 GO:0044271 Not Cancer Driver No 54 0.205 0 0 0.0 0
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0044271 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 GO:0044271 Not Cancer Driver No 28 0.105 0 0 0.0 1
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 GO:0044271 Not Cancer Driver No 120 0.109 114 12 0.105 0
ACMSD ACMSD Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 GO:0044271 Not Cancer Driver No 65 0.193 9 2 0.222 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0044271 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0044271 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0044271 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACSF3_ENST00000406948 ACSF3 Q4G176 Malonate--CoA ligase ACSF3, mitochondrial chr16 GO:0044271 Not Cancer Driver No 87 0.151 48 11 0.229 9
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 GO:0044271 Not Cancer Driver No 85 0.122 27 1 0.037 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0044271 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0044271 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACSL5_ENST00000354655 ACSL5 Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 chr10 GO:0044271 Not Cancer Driver No 98 0.143 22 5 0.227 0
ACSL6_ENST00000379240 ACSL6 Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 chr5 GO:0044271 Census Yes 120 0.172 34 3 0.088 0
ACSS1 ACSS1 Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial chr20 GO:0044271 Not Cancer Driver No 79 0.115 76 6 0.079 0
ACSS2_ENST00000360596 ACSS2 Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic chr20 GO:0044271 Not Cancer Driver No 62 0.088 111 6 0.054 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0044271 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADA2 ADA2 Q9NZK5 Adenosine deaminase 2 chr22 GO:0044271 Not Cancer Driver No 97 0.19 1 0 0.0 10
ADAL ADAL Q6DHV7 Adenosine deaminase-like protein chr15 GO:0044271 Not Cancer Driver No 33 0.093 57 9 0.158 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0044271 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0044271 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0044271 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0044271 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0044271 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0044271 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0044271 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY7_ENST00000254235 ADCY7 P51828 Adenylate cyclase type 7 chr16 GO:0044271 Not Cancer Driver No 144 0.133 121 17 0.14 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0044271 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 GO:0044271 Not Cancer Driver No 195 0.144 271 42 0.155 0
ADK ADK P55263 Adenosine kinase chr10 GO:0044271 Not Cancer Driver No 29 0.08 33 2 0.061 3
ADSL ADSL P30566 Adenylosuccinate lyase chr22 GO:0044271 Not Cancer Driver No 68 0.14 36 9 0.25 27
ADSS ADSS2 P30520 Adenylosuccinate synthetase isozyme 2 chr1 GO:0044271 Not Cancer Driver No 49 0.107 48 4 0.083 0
ADSSL1_ENST00000330877 ADSS1 Q8N142 Adenylosuccinate synthetase isozyme 1 chr14 GO:0044271 Not Cancer Driver No 74 0.162 68 6 0.088 1
AFMID_ENST00000409257 AFMID Q63HM1 Kynurenine formamidase chr17 GO:0044271 Not Cancer Driver No 46 0.152 12 1 0.083 0
AGMAT AGMAT Q9BSE5 Agmatinase, mitochondrial chr1 GO:0044271 Not Cancer Driver No 53 0.151 106 10 0.094 0
AK1_ENST00000373176 AK1 P00568 Adenylate kinase isoenzyme 1 chr9 GO:0044271 Not Cancer Driver No 19 0.098 55 3 0.055 4
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 GO:0044271 Not Cancer Driver No 23 0.096 76 12 0.158 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 GO:0044271 Not Cancer Driver No 23 0.101 33 3 0.091 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 GO:0044271 Not Cancer Driver No 26 0.117 24 3 0.125 0
AK5 AK5 Q9Y6K8 Adenylate kinase isoenzyme 5 chr1 GO:0044271 Not Cancer Driver No 116 0.206 161 44 0.273 0
AK6 AK6 Q9Y3D8 Adenylate kinase isoenzyme 6 chr5 GO:0044271 Not Cancer Driver No 6 0.035 13 0 0.0 0
AK7 AK7 Q96M32 Adenylate kinase 7 chr14 GO:0044271 Not Cancer Driver No 126 0.174 181 42 0.232 1
AK8 AK8 Q96MA6 Adenylate kinase 8 chr9 GO:0044271 Not Cancer Driver No 74 0.154 53 8 0.151 0
AK9 AK9 Q5TCS8 Adenylate kinase 9 chr6 GO:0044271 Not Cancer Driver No 235 0.123 589 58 0.098 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0044271 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0044271 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALAS1_ENST00000484952 ALAS1 P13196 5-aminolevulinate synthase, non-specific, mitochondrial chr3 GO:0044271 Not Cancer Driver No 68 0.106 177 16 0.09 0
ALAS2 ALAS2 P22557 5-aminolevulinate synthase, erythroid-specific, mitochondrial chrX GO:0044271 Not Cancer Driver No 107 0.182 87 17 0.195 24
ALDH7A1 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 GO:0044271 Not Cancer Driver No 52 0.096 26 1 0.038 8
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 GO:0044271 Not Cancer Driver No 57 0.115 16 0 0.0 0
AMD1 AMD1 P17707 S-adenosylmethionine decarboxylase proenzyme chr6 GO:0044271 Not Cancer Driver No 42 0.126 9 1 0.111 0
AMDHD2_ENST00000293971 AMDHD2 Q9Y303 N-acetylglucosamine-6-phosphate deacetylase chr16 GO:0044271 Not Cancer Driver No 44 0.108 25 6 0.24 0
AMPD1 AMPD1 P23109 AMP deaminase 1 chr1 GO:0044271 Not Cancer Driver No 218 0.292 112 25 0.223 2
AMPD2_ENST00000528667 AMPD2 Q01433 AMP deaminase 2 chr1 GO:0044271 Not Cancer Driver No 93 0.106 275 27 0.098 3
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0044271 Not Cancer Driver No 132 0.172 207 38 0.184 10
ANG ANG P03950 Angiogenin chr14 GO:0044271 Not Cancer Driver No 19 0.129 36 2 0.056 14
AP000311.1 AP000311.1 H7C0C1 ATP synthase subunit O, mitochondrial (Fragment) chr21 GO:0044271 Not Cancer Driver No 27 0.112 27 5 0.185 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0044271 Not Cancer Driver No 126 0.115 316 31 0.098 1
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 GO:0044271 Not Cancer Driver No 16 0.089 0 0 0.0 8
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0044271 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0044271 Not Cancer Driver No 25 0.071 58 3 0.052 0
ASAH1_ENST00000262097 ASAH1 Q13510 Acid ceramidase chr8 GO:0044271 Not Cancer Driver No 47 0.119 10 3 0.3 14
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0044271 Not Cancer Driver No 71 0.091 140 24 0.171 0
ASAH2B_ENST00000374006 ASAH2B P0C7U1 Putative inactive neutral ceramidase B chr10 GO:0044271 Not Cancer Driver No 9 0.055 14 1 0.071 0
ASL_ENST00000395332 ASL P04424 Argininosuccinate lyase chr7 GO:0044271 Not Cancer Driver No 77 0.166 36 2 0.056 63
ASMT_ENST00000381229 ASMT P46597 Acetylserotonin O-methyltransferase chrX GO:0044271 Not Cancer Driver No 67 0.194 1 0 0.0 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0044271 Not Cancer Driver No 81 0.144 11 0 0.0 3
ASPDH ASPDH A6ND91 Aspartate dehydrogenase domain-containing protein chr19 GO:0044271 Not Cancer Driver No 27 0.095 81 5 0.062 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0044271 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0044271 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0044271 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0044271 Census Yes 74 0.125 25 1 0.04 1
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0044271 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0044271 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 GO:0044271 Not Cancer Driver No 39 0.131 11 0 0.0 0
ATP5F1D_ENST00000591660 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 GO:0044271 Not Cancer Driver No 7 0.042 5 1 0.2 2
ATP5F1E_ENST00000395663 ATP5F1E P56381 ATP synthase subunit epsilon, mitochondrial chr20 GO:0044271 Not Cancer Driver No 3 0.059 1 0 0.0 1
ATP5ME ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 GO:0044271 Not Cancer Driver No 6 0.087 18 2 0.111 0
ATP5MF ATP5MF P56134 ATP synthase subunit f, mitochondrial chr7 GO:0044271 Not Cancer Driver No 22 0.234 0 0 0.0 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 GO:0044271 Not Cancer Driver No 16 0.155 0 0 0.0 0
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 GO:0044271 Not Cancer Driver No 37 0.145 2 0 0.0 0
ATP5PD ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 GO:0044271 Not Cancer Driver No 12 0.075 15 0 0.0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 GO:0044271 Not Cancer Driver No 14 0.13 15 1 0.067 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 GO:0044271 Not Cancer Driver No 19 0.089 9 2 0.222 0
AZIN1 AZIN1 O14977 Antizyme inhibitor 1 chr8 GO:0044271 Not Cancer Driver No 39 0.087 10 2 0.2 0
AZIN2_ENST00000294517 AZIN2 Q96A70 Antizyme inhibitor 2 chr1 GO:0044271 Not Cancer Driver No 51 0.111 14 0 0.0 0
B3GALT1 B3GALT1 Q9Y5Z6 Beta-1,3-galactosyltransferase 1 chr2 GO:0044271 Not Cancer Driver No 76 0.233 0 0 0.0 0
B3GALT2 B3GALT2 O43825 Beta-1,3-galactosyltransferase 2 chr1 GO:0044271 Not Cancer Driver No 61 0.145 70 13 0.186 0
B3GALT4 B3GALT4 O96024 Beta-1,3-galactosyltransferase 4 chr6 GO:0044271 Not Cancer Driver No 46 0.122 54 6 0.111 0
B4GALNT1 B4GALNT1 Q00973 Beta-1,4 N-acetylgalactosaminyltransferase 1 chr12 GO:0044271 Not Cancer Driver No 80 0.15 74 14 0.189 2
B4GALT3_ENST00000367998 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 GO:0044271 Not Cancer Driver No 56 0.142 171 27 0.158 0
B4GALT4 B4GALT4 O60513 Beta-1,4-galactosyltransferase 4 chr3 GO:0044271 Not Cancer Driver No 49 0.142 14 4 0.286 0
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 GO:0044271 Not Cancer Driver No 53 0.137 20 1 0.05 0
B4GALT6 B4GALT6 Q9UBX8 Beta-1,4-galactosyltransferase 6 chr18 GO:0044271 Not Cancer Driver No 47 0.123 13 2 0.154 0
BBOX1_ENST00000525090 BBOX1 O75936 Gamma-butyrobetaine dioxygenase chr11 GO:0044271 Not Cancer Driver No 59 0.152 0 0 0.0 0
BDH2 BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 chr4 GO:0044271 Not Cancer Driver No 24 0.098 22 1 0.045 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0044271 Not Cancer Driver No 90 0.133 399 45 0.113 4
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0044271 Not Cancer Driver No 71 0.203 0 0 0.0 0
CAD CAD P27708 CAD protein chr2 GO:0044271 Not Cancer Driver No 287 0.129 368 52 0.141 1
CARNS1_ENST00000307823 CARNS1 A5YM72 Carnosine synthase 1 chr11 GO:0044271 Not Cancer Driver No 74 0.089 42 4 0.095 0
CAVIN1 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 GO:0044271 Not Cancer Driver No 66 0.169 280 50 0.179 0
CD3EAP_ENST00000309424 POLR1G O15446 DNA-directed RNA polymerase I subunit RPA34 chr19 GO:0044271 Not Cancer Driver No 52 0.102 491 50 0.102 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0044271 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0044271 Not Cancer Driver No 41 0.118 38 5 0.132 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0044271 Census, Compendium Yes 12 0.034 342 12 0.035 1
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0044271 Not Cancer Driver No 82 0.176 201 33 0.164 0
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0044271 Not Cancer Driver No 30 0.135 49 5 0.102 0
CHAC2 CHAC2 Q8WUX2 Glutathione-specific gamma-glutamylcyclotransferase 2 chr2 GO:0044271 Not Cancer Driver No 21 0.114 11 2 0.182 0
CHDH CHDH Q8NE62 Choline dehydrogenase, mitochondrial chr3 GO:0044271 Not Cancer Driver No 59 0.099 116 7 0.06 0
CMPK2 CMPK2 Q5EBM0 UMP-CMP kinase 2, mitochondrial chr2 GO:0044271 Not Cancer Driver No 41 0.091 99 8 0.081 0
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 GO:0044271 Not Cancer Driver No 57 0.101 50 4 0.08 1
COX10 COX10 Q12887 Protoheme IX farnesyltransferase, mitochondrial chr17 GO:0044271 Not Cancer Driver No 80 0.181 74 18 0.243 7
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 GO:0044271 Not Cancer Driver No 48 0.117 0 0 0.0 2
CPOX CPOX P36551 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial chr3 GO:0044271 Not Cancer Driver No 49 0.108 126 7 0.056 17
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0044271 Not Cancer Driver No 368 0.245 73 22 0.301 140
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 GO:0044271 Not Cancer Driver No 11 0.074 113 4 0.035 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 GO:0044271 Not Cancer Driver No 70 0.118 83 10 0.12 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX GO:0044271 Not Cancer Driver No 57 0.097 65 9 0.138 0
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 GO:0044271 Not Cancer Driver No 17 0.113 58 2 0.034 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 GO:0044271 Not Cancer Driver No 42 0.14 24 3 0.125 9
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0044271 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAO DAO P14920 D-amino-acid oxidase chr12 GO:0044271 Not Cancer Driver No 103 0.297 28 13 0.464 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0044271 Not Cancer Driver No 125 0.203 71 17 0.239 3
DCAKD DCAKD Q8WVC6 Dephospho-CoA kinase domain-containing protein chr17 GO:0044271 Not Cancer Driver No 31 0.134 2 0 0.0 0
DCK DCK P27707 Deoxycytidine kinase chr4 GO:0044271 Not Cancer Driver No 29 0.112 22 4 0.182 0
DCTD_ENST00000438320 DCTD P32321 Deoxycytidylate deaminase chr4 GO:0044271 Not Cancer Driver No 33 0.185 3 0 0.0 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0044271 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0044271 Not Cancer Driver No 98 0.204 5 0 0.0 9
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0044271 Census Yes 74 0.121 225 23 0.102 0
DGUOK DGUOK Q16854 Deoxyguanosine kinase, mitochondrial chr2 GO:0044271 Not Cancer Driver No 25 0.09 17 1 0.059 6
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0044271 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 GO:0044271 Not Cancer Driver No 25 0.134 20 0 0.0 0
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 GO:0044271 Not Cancer Driver No 44 0.111 96 11 0.115 10
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0044271 Compendium Yes 182 0.143 331 42 0.127 0
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0044271 Not Cancer Driver No 204 0.13 396 53 0.134 0
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 GO:0044271 Not Cancer Driver No 63 0.097 294 42 0.143 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0044271 Not Cancer Driver No 67 0.132 17 0 0.0 10
DTYMK DTYMK P23919 Thymidylate kinase chr2 GO:0044271 Not Cancer Driver No 10 0.047 0 0 0.0 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0044271 Not Cancer Driver No 19 0.075 128 8 0.062 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0044271 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0044271 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELL2 ELL2 O00472 RNA polymerase II elongation factor ELL2 chr5 GO:0044271 Not Cancer Driver No 90 0.141 421 63 0.15 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0044271 Not Cancer Driver No 50 0.126 186 13 0.07 0
ELOVL1_ENST00000372458 ELOVL1 Q9BW60 Elongation of very long chain fatty acids protein 1 chr1 GO:0044271 Not Cancer Driver No 32 0.115 0 0 0.0 1
ELOVL2 ELOVL2 Q9NXB9 Elongation of very long chain fatty acids protein 2 chr6 GO:0044271 Not Cancer Driver No 57 0.193 8 2 0.25 0
ELOVL3 ELOVL3 Q9HB03 Elongation of very long chain fatty acids protein 3 chr10 GO:0044271 Not Cancer Driver No 42 0.156 1 1 1.0 0
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 GO:0044271 Not Cancer Driver No 68 0.217 23 6 0.261 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0044271 Not Cancer Driver No 34 0.114 25 4 0.16 2
ELOVL6 ELOVL6 Q9H5J4 Elongation of very long chain fatty acids protein 6 chr4 GO:0044271 Not Cancer Driver No 40 0.151 0 0 0.0 0
ELOVL7_ENST00000425382 ELOVL7 A1L3X0 Elongation of very long chain fatty acids protein 7 chr5 GO:0044271 Not Cancer Driver No 41 0.146 10 2 0.2 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0044271 Not Cancer Driver No 46 0.093 5 0 0.0 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0044271 Census, Compendium Yes 120 0.138 449 53 0.118 6
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0044271 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0044271 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0044271 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0044271 Not Cancer Driver No 26 0.154 10 3 0.3 0
FA2H FA2H Q7L5A8 Fatty acid 2-hydroxylase chr16 GO:0044271 Not Cancer Driver No 33 0.089 73 0 0.0 3
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 GO:0044271 Not Cancer Driver No 81 0.138 59 6 0.102 1
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0044271 Not Cancer Driver No 12 0.038 186 4 0.022 6
FPGS FPGS Q05932 Folylpolyglutamate synthase, mitochondrial chr9 GO:0044271 Not Cancer Driver No 68 0.116 141 18 0.128 0
FUK FCSK Q8N0W3 L-fucose kinase chr16 GO:0044271 Not Cancer Driver No 102 0.094 26 1 0.038 0
GAL3ST1 GAL3ST1 Q99999 Galactosylceramide sulfotransferase chr22 GO:0044271 Not Cancer Driver No 103 0.243 15 2 0.133 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 GO:0044271 Not Cancer Driver No 61 0.083 75 9 0.12 17
GART_ENST00000381815 GART P22102 Trifunctional purine biosynthetic protein adenosine-3 chr21 GO:0044271 Not Cancer Driver No 96 0.095 50 6 0.12 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0044271 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0044271 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCDH_ENST00000591470 GCDH Q92947 Glutaryl-CoA dehydrogenase, mitochondrial chr19 GO:0044271 Not Cancer Driver No 57 0.13 37 5 0.135 58
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0044271 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCHFR GCHFR P30047 GTP cyclohydrolase 1 feedback regulatory protein chr15 GO:0044271 Not Cancer Driver No 9 0.107 20 0 0.0 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0044271 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0044271 Not Cancer Driver No 32 0.117 31 3 0.097 0
GFPT1 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 GO:0044271 Not Cancer Driver No 81 0.116 75 8 0.107 13
GFPT2 GFPT2 O94808 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 chr5 GO:0044271 Not Cancer Driver No 121 0.177 42 8 0.19 0
GGT1_ENST00000248923 GGT1 P19440 Glutathione hydrolase 1 proenzyme chr22 GO:0044271 Not Cancer Driver No 83 0.146 88 14 0.159 0
GGT2 GGT2P P36268 Inactive glutathione hydrolase 2 chr22 GO:0044271 Not Cancer Driver No 5 0.009 48 1 0.021 0
GGT5_ENST00000327365 GGT5 P36269 Glutathione hydrolase 5 proenzyme chr22 GO:0044271 Not Cancer Driver No 99 0.169 122 27 0.221 0
GGT6_ENST00000574154 GGT6 Q6P531 Glutathione hydrolase 6 chr17 GO:0044271 Not Cancer Driver No 51 0.103 211 32 0.152 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0044271 Not Cancer Driver No 77 0.116 170 14 0.082 0
GGTLC1_ENST00000278765 GGTLC1 Q9BX51 Glutathione hydrolase light chain 1 chr20 GO:0044271 Not Cancer Driver No 63 0.28 81 17 0.21 0
GGTLC2 GGTLC2 Q14390 Glutathione hydrolase light chain 2 chr22 GO:0044271 Not Cancer Driver No 25 0.115 119 11 0.092 0
GMDS GMDS O60547 GDP-mannose 4,6 dehydratase chr6 GO:0044271 Not Cancer Driver No 51 0.137 53 6 0.113 0
GMPPB_ENST00000480687 GMPPB Q9Y5P6 Mannose-1-phosphate guanyltransferase beta chr3 GO:0044271 Not Cancer Driver No 39 0.108 10 1 0.1 19
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 GO:0044271 Census, Compendium Yes 88 0.127 76 10 0.132 0
GNPNAT1 GNPNAT1 Q96EK6 Glucosamine 6-phosphate N-acetyltransferase chr14 GO:0044271 Not Cancer Driver No 19 0.103 24 5 0.208 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 GO:0044271 Not Cancer Driver No 124 0.202 200 42 0.21 0
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 GO:0044271 Not Cancer Driver No 61 0.129 49 6 0.122 14
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0044271 Not Cancer Driver No 33 0.104 80 6 0.075 0
GTF2H5 GTF2H5 Q6ZYL4 General transcription factor IIH subunit 5 chr6 GO:0044271 Not Cancer Driver No 7 0.099 0 0 0.0 1
GTF2I GTF2I P78347 General transcription factor II-I chr7 GO:0044271 Compendium Yes 74 0.074 365 27 0.074 0
GTF3A GTF3A Q92664 Transcription factor IIIA chr13 GO:0044271 Not Cancer Driver No 20 0.055 73 7 0.096 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 GO:0044271 Not Cancer Driver No 323 0.153 735 114 0.155 0
GTF3C2 GTF3C2 Q8WUA4 General transcription factor 3C polypeptide 2 chr2 GO:0044271 Not Cancer Driver No 111 0.122 394 45 0.114 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 GO:0044271 Not Cancer Driver No 109 0.123 195 22 0.113 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 GO:0044271 Not Cancer Driver No 76 0.092 164 13 0.079 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 GO:0044271 Not Cancer Driver No 75 0.145 157 21 0.134 0
GTF3C6 GTF3C6 Q969F1 General transcription factor 3C polypeptide 6 chr6 GO:0044271 Not Cancer Driver No 19 0.089 130 11 0.085 0
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:0044271 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:0044271 Not Cancer Driver No 191 0.261 187 48 0.257 0
GUCY1B1_ENST00000264424 GUCY1B1 Q02153 Guanylate cyclase soluble subunit beta-1 chr4 GO:0044271 Not Cancer Driver No 103 0.166 83 20 0.241 0
GUCY2C GUCY2C P25092 Guanylyl cyclase C chr12 GO:0044271 Not Cancer Driver No 209 0.195 51 7 0.137 2
GUCY2D GUCY2D Q02846 Retinal guanylyl cyclase 1 chr17 GO:0044271 Not Cancer Driver No 138 0.125 205 34 0.166 32
GUCY2F GUCY2F P51841 Retinal guanylyl cyclase 2 chrX GO:0044271 Not Cancer Driver No 230 0.208 88 15 0.17 0
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 GO:0044271 Not Cancer Driver No 28 0.142 71 9 0.127 0
HAAO HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase chr2 GO:0044271 Not Cancer Driver No 40 0.14 30 2 0.067 0
HACD1 HACD1 B0YJ81 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 chr10 GO:0044271 Not Cancer Driver No 74 0.257 63 21 0.333 0
HACD2 HACD2 Q6Y1H2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 chr3 GO:0044271 Not Cancer Driver No 16 0.063 14 0 0.0 0
HAGH HAGH Q16775 Hydroxyacylglutathione hydrolase, mitochondrial chr16 GO:0044271 Not Cancer Driver No 26 0.084 41 1 0.024 0
HDC HDC P19113 Histidine decarboxylase chr15 GO:0044271 Not Cancer Driver No 163 0.246 96 24 0.25 0
HELB HELB Q8NG08 DNA helicase B chr12 GO:0044271 Not Cancer Driver No 140 0.129 300 38 0.127 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0044271 Not Cancer Driver No 128 0.105 559 51 0.091 0
HMBS HMBS P08397 Porphobilinogen deaminase chr11 GO:0044271 Not Cancer Driver No 46 0.127 57 11 0.193 89
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0044271 Not Cancer Driver No 22 0.101 3 0 0.0 62
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:0044271 Not Cancer Driver No 32 0.103 9 0 0.0 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0044271 Not Cancer Driver No 59 0.112 335 37 0.11 0
HTD2_ENST00000461393 HTD2 P86397 Hydroxyacyl-thioester dehydratase type 2, mitochondrial chr3 GO:0044271 Not Cancer Driver No 1 0.006 0 0 0.0 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0044271 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0044271 Not Cancer Driver No 107 0.109 399 45 0.113 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0044271 Not Cancer Driver No 82 0.203 41 8 0.195 0
IDO2 IDO2 Q6ZQW0 Indoleamine 2,3-dioxygenase 2 chr8 GO:0044271 Not Cancer Driver No 93 0.221 35 5 0.143 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 GO:0044271 Not Cancer Driver No 75 0.146 13 1 0.077 7
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0044271 Not Cancer Driver No 70 0.136 6 1 0.167 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0044271 Not Cancer Driver No 25 0.049 359 12 0.033 0
IREB2 IREB2 P48200 Iron-responsive element-binding protein 2 chr15 GO:0044271 Not Cancer Driver No 126 0.131 107 13 0.121 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0044271 Not Cancer Driver No 88 0.147 160 15 0.094 12
KL KL Q9UEF7 Klotho chr13 GO:0044271 Not Cancer Driver No 175 0.173 104 5 0.048 1
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0044271 Not Cancer Driver No 77 0.158 0 0 0.0 0
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0044271 Not Cancer Driver No 103 0.222 20 5 0.25 1
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0044271 Not Cancer Driver No 22 0.104 0 0 0.0 1
MARC1 MTARC1 Q5VT66 Mitochondrial amidoxime-reducing component 1 chr1 GO:0044271 Not Cancer Driver No 49 0.145 26 6 0.231 0
MARC2 MTARC2 Q969Z3 Mitochondrial amidoxime reducing component 2 chr1 GO:0044271 Not Cancer Driver No 33 0.099 4 0 0.0 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0044271 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0044271 Not Cancer Driver No 46 0.096 249 22 0.088 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0044271 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MED18_ENST00000398997 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 GO:0044271 Not Cancer Driver No 35 0.168 10 2 0.2 0
MGST2 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 GO:0044271 Not Cancer Driver No 11 0.075 0 0 0.0 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0044271 Not Cancer Driver No 41 0.083 82 0 0.0 0
MOXD1 MOXD1 Q6UVY6 DBH-like monooxygenase protein 1 chr6 GO:0044271 Not Cancer Driver No 99 0.162 29 7 0.241 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0044271 Not Cancer Driver No 13 0.102 0 0 0.0 0
MPI MPI P34949 Mannose-6-phosphate isomerase chr15 GO:0044271 Not Cancer Driver No 35 0.083 61 10 0.164 13
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 GO:0044271 Not Cancer Driver No 37 0.131 15 0 0.0 0
MTERF1 MTERF1 Q99551 Transcription termination factor 1, mitochondrial chr7 GO:0044271 Not Cancer Driver No 48 0.12 0 0 0.0 0
MTERF2 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 GO:0044271 Not Cancer Driver No 49 0.127 0 0 0.0 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0044271 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 GO:0044271 Not Cancer Driver No 117 0.12 139 11 0.079 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0044271 Census, Compendium Yes 379 0.149 296 37 0.125 18
NADK2 NADK2 Q4G0N4 NAD kinase 2, mitochondrial chr5 GO:0044271 Not Cancer Driver No 42 0.095 89 3 0.034 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 GO:0044271 Not Cancer Driver No 59 0.132 91 18 0.198 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 GO:0044271 Not Cancer Driver No 82 0.116 27 8 0.296 3
NAGS NAGS Q8N159 N-acetylglutamate synthase, mitochondrial chr17 GO:0044271 Not Cancer Driver No 35 0.066 116 6 0.052 6
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 GO:0044271 Not Cancer Driver No 50 0.102 27 5 0.185 0
NANP NANP Q8TBE9 N-acylneuraminate-9-phosphatase chr20 GO:0044271 Not Cancer Driver No 18 0.073 4 0 0.0 0
NANS NANS Q9NR45 Sialic acid synthase chr9 GO:0044271 Not Cancer Driver No 29 0.081 45 1 0.022 6
NAPRT NAPRT Q6XQN6 Nicotinate phosphoribosyltransferase chr8 GO:0044271 Not Cancer Driver No 38 0.071 98 11 0.112 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0044271 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0044271 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 GO:0044271 Not Cancer Driver No 32 0.109 148 15 0.101 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0044271 Not Cancer Driver No 11 0.072 10 0 0.0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0044271 Not Cancer Driver No 13 0.086 11 1 0.091 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0044271 Not Cancer Driver No 10 0.059 4 0 0.0 0
NME4 NME4 O00746 Nucleoside diphosphate kinase, mitochondrial chr16 GO:0044271 Not Cancer Driver No 13 0.07 41 4 0.098 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0044271 Not Cancer Driver No 17 0.08 6 0 0.0 0
NME6_ENST00000415053 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0044271 Not Cancer Driver No 23 0.124 22 3 0.136 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 GO:0044271 Not Cancer Driver No 53 0.141 0 0 0.0 0
NME9_ENST00000333911 NME9 Q86XW9 Thioredoxin domain-containing protein 6 chr3 GO:0044271 Not Cancer Driver No 51 0.155 145 27 0.186 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 GO:0044271 Not Cancer Driver No 39 0.14 49 7 0.143 28
NMNAT2 NMNAT2 Q9BZQ4 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 chr1 GO:0044271 Not Cancer Driver No 54 0.176 22 1 0.045 0
NMNAT3 NMNAT3 Q96T66 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 chr3 GO:0044271 Not Cancer Driver No 32 0.127 53 6 0.113 0
NMRK1_ENST00000361092 NMRK1 Q9NWW6 Nicotinamide riboside kinase 1 chr9 GO:0044271 Not Cancer Driver No 23 0.116 6 0 0.0 0
NMRK2_ENST00000168977 NMRK2 Q9NPI5 Nicotinamide riboside kinase 2 chr19 GO:0044271 Not Cancer Driver No 25 0.109 53 9 0.17 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0044271 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0044271 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0044271 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0044271 Not Cancer Driver No 168 0.14 347 38 0.11 0
NPM3 NPM3 O75607 Nucleoplasmin-3 chr10 GO:0044271 Not Cancer Driver No 23 0.129 78 11 0.141 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0044271 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPPB NPPB P16860 Natriuretic peptides B chr1 GO:0044271 Not Cancer Driver No 31 0.231 104 28 0.269 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0044271 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0044271 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0044271 Not Cancer Driver No 144 0.138 89 18 0.202 20
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0044271 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0044271 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0044271 Not Cancer Driver No 110 0.184 261 38 0.146 0
NT5E NT5E P21589 5'-nucleotidase chr6 GO:0044271 Not Cancer Driver No 61 0.106 26 2 0.077 1
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0044271 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT2_ENST00000346365 NUDT2 P50583 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] chr9 GO:0044271 Not Cancer Driver No 16 0.109 24 1 0.042 0
OAZ1 OAZ1 P54368 Ornithine decarboxylase antizyme 1 chr19 GO:0044271 Not Cancer Driver No 30 0.132 109 12 0.11 0
OAZ2 OAZ2 O95190 Ornithine decarboxylase antizyme 2 chr15 GO:0044271 Not Cancer Driver No 15 0.079 11 0 0.0 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 GO:0044271 Not Cancer Driver No 37 0.157 33 2 0.061 0
ODC1_ENST00000405333 ODC1 P11926 Ornithine decarboxylase chr2 GO:0044271 Not Cancer Driver No 46 0.1 33 7 0.212 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0044271 Not Cancer Driver No 22 0.144 9 1 0.111 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0044271 Not Cancer Driver No 83 0.103 386 39 0.101 0
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX GO:0044271 Not Cancer Driver No 89 0.251 24 4 0.167 111
PAH PAH P00439 Phenylalanine-4-hydroxylase chr12 GO:0044271 Not Cancer Driver No 133 0.294 13 4 0.308 222
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 GO:0044271 Not Cancer Driver No 23 0.054 35 3 0.086 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0044271 Not Cancer Driver No 129 0.133 254 37 0.146 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 GO:0044271 Not Cancer Driver No 62 0.104 248 17 0.069 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0044271 Not Cancer Driver No 46 0.081 206 14 0.068 30
PANK3 PANK3 Q9H999 Pantothenate kinase 3 chr5 GO:0044271 Not Cancer Driver No 41 0.111 0 0 0.0 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 GO:0044271 Not Cancer Driver No 92 0.119 71 15 0.211 0
PAOX PAOX Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase chr10 GO:0044271 Not Cancer Driver No 70 0.137 29 0 0.0 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 GO:0044271 Not Cancer Driver No 94 0.151 82 14 0.171 0
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0044271 Not Cancer Driver No 81 0.132 100 7 0.07 4
PARP10_ENST00000313028 PARP10 Q53GL7 Protein mono-ADP-ribosyltransferase PARP10 chr8 GO:0044271 Not Cancer Driver No 122 0.119 552 68 0.123 0
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0044271 Not Cancer Driver No 37 0.115 33 3 0.091 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0044271 Not Cancer Driver No 110 0.129 45 3 0.067 0
PCBD1 PCBD1 P61457 Pterin-4-alpha-carbinolamine dehydratase chr10 GO:0044271 Not Cancer Driver No 8 0.077 7 0 0.0 3
PCBD2_ENST00000254908 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 GO:0044271 Not Cancer Driver No 6 0.046 3 0 0.0 0
PCF11 PCF11 O94913 Pre-mRNA cleavage complex 2 protein Pcf11 chr11 GO:0044271 Not Cancer Driver No 211 0.136 1250 189 0.151 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX GO:0044271 Not Cancer Driver No 70 0.179 43 6 0.14 20
PDHA2 PDHA2 P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial chr4 GO:0044271 Not Cancer Driver No 163 0.42 41 17 0.415 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 GO:0044271 Not Cancer Driver No 32 0.089 4 0 0.0 2
PDHX PDHX O00330 Pyruvate dehydrogenase protein X component, mitochondrial chr11 GO:0044271 Not Cancer Driver No 62 0.124 179 28 0.156 0
PDXK PDXK O00764 Pyridoxal kinase chr21 GO:0044271 Not Cancer Driver No 27 0.087 47 6 0.128 2
PEMT_ENST00000395783 PEMT Q9UBM1 Phosphatidylethanolamine N-methyltransferase chr17 GO:0044271 Not Cancer Driver No 21 0.106 1 0 0.0 0
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 GO:0044271 Not Cancer Driver No 157 0.117 380 36 0.095 0
PGM2 PGM2 Q96G03 Phosphopentomutase chr4 GO:0044271 Not Cancer Driver No 79 0.129 108 13 0.12 0
PGM3_ENST00000513973 PGM3 O95394 Phosphoacetylglucosamine mutase chr6 GO:0044271 Not Cancer Driver No 78 0.144 77 8 0.104 7
PMM1 PMM1 Q92871 Phosphomannomutase 1 chr22 GO:0044271 Not Cancer Driver No 37 0.141 15 0 0.0 0
PMM2 PMM2 O15305 Phosphomannomutase 2 chr16 GO:0044271 Not Cancer Driver No 25 0.102 16 1 0.062 66
PNMT PNMT P11086 Phenylethanolamine N-methyltransferase chr17 GO:0044271 Not Cancer Driver No 36 0.128 44 4 0.091 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0044271 Not Cancer Driver No 38 0.131 29 2 0.069 5
PNPLA1 PNPLA1 Q8N8W4 Omega-hydroxyceramide transacylase chr6 GO:0044271 Not Cancer Driver No 89 0.167 253 48 0.19 2
PNPO PNPO Q9NVS9 Pyridoxine-5'-phosphate oxidase chr17 GO:0044271 Not Cancer Driver No 23 0.088 62 8 0.129 3
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:0044271 Not Cancer Driver No 185 0.127 347 45 0.13 3
POLA2 POLA2 Q14181 DNA polymerase alpha subunit B chr11 GO:0044271 Not Cancer Driver No 63 0.105 102 16 0.157 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0044271 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0044271 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0044271 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0044271 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0044271 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0044271 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0044271 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0044271 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLR1B_ENST00000263331 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 GO:0044271 Not Cancer Driver No 120 0.106 69 10 0.145 2
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 GO:0044271 Not Cancer Driver No 39 0.093 85 6 0.071 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0044271 Not Cancer Driver No 21 0.168 22 5 0.227 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 GO:0044271 Not Cancer Driver No 10 0.149 0 0 0.0 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 GO:0044271 Not Cancer Driver No 23 0.113 33 6 0.182 0
POLR3K POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 GO:0044271 Not Cancer Driver No 10 0.093 0 0 0.0 1
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0044271 Census Yes 72 0.143 44 4 0.091 3
PPAT PPAT Q06203 Amidophosphoribosyltransferase chr4 GO:0044271 Not Cancer Driver No 66 0.128 48 4 0.083 0
PPCDC PPCDC Q96CD2 Phosphopantothenoylcysteine decarboxylase chr15 GO:0044271 Not Cancer Driver No 13 0.064 6 0 0.0 0
PPCS PPCS Q9HAB8 Phosphopantothenate--cysteine ligase chr1 GO:0044271 Not Cancer Driver No 39 0.125 13 0 0.0 2
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 GO:0044271 Not Cancer Driver No 48 0.101 34 6 0.176 56
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0044271 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 GO:0044271 Compendium Yes 45 0.149 0 0 0.0 0
PRG3 PRG3 Q9Y2Y8 Proteoglycan 3 chr11 GO:0044271 Not Cancer Driver No 40 0.178 60 12 0.2 0
PRIM1 PRIM1 P49642 DNA primase small subunit chr12 GO:0044271 Not Cancer Driver No 31 0.074 22 1 0.045 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0044271 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0044271 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0044271 Not Cancer Driver No 83 0.13 72 6 0.083 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0044271 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0044271 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0044271 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0044271 Census, Compendium Yes 69 0.282 205 49 0.239 1
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0044271 Not Cancer Driver No 29 0.129 3 0 0.0 0
PSAT1 PSAT1 Q9Y617 Phosphoserine aminotransferase chr9 GO:0044271 Not Cancer Driver No 54 0.146 3 1 0.333 3
PSTK PSTK Q8IV42 L-seryl-tRNA(Sec) kinase chr10 GO:0044271 Not Cancer Driver No 48 0.138 79 15 0.19 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0044271 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTS PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 GO:0044271 Not Cancer Driver No 9 0.062 22 1 0.045 24
QDPR QDPR P09417 Dihydropteridine reductase chr4 GO:0044271 Not Cancer Driver No 41 0.168 25 3 0.12 16
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 GO:0044271 Not Cancer Driver No 29 0.098 7 1 0.143 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0044271 Census, Compendium Yes 70 0.152 167 14 0.084 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0044271 Not Cancer Driver No 33 0.126 23 0 0.0 0
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0044271 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0044271 Not Cancer Driver No 379 0.121 1665 211 0.127 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0044271 Not Cancer Driver No 15 0.097 1 0 0.0 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0044271 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0044271 Not Cancer Driver No 56 0.092 293 25 0.085 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0044271 Not Cancer Driver No 74 0.093 41 7 0.171 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0044271 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:0044271 Not Cancer Driver No 40 0.103 48 0 0.0 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0044271 Not Cancer Driver No 66 0.101 115 15 0.13 0
RSAD1 RSAD1 Q9HA92 Radical S-adenosyl methionine domain-containing protein 1, mitochondrial chr17 GO:0044271 Not Cancer Driver No 68 0.154 88 13 0.148 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0044271 Compendium Yes 90 0.195 184 26 0.141 0
SAMD8 SAMD8 Q96LT4 Sphingomyelin synthase-related protein 1 chr10 GO:0044271 Not Cancer Driver No 40 0.096 0 0 0.0 0
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 GO:0044271 Not Cancer Driver No 64 0.124 111 14 0.126 1
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0044271 Not Cancer Driver No 56 0.109 83 4 0.048 1
SAT1 SAT1 P21673 Diamine acetyltransferase 1 chrX GO:0044271 Not Cancer Driver No 29 0.17 0 0 0.0 0
SAT2 SAT2 Q96F10 Thialysine N-epsilon-acetyltransferase chr17 GO:0044271 Not Cancer Driver No 14 0.082 0 0 0.0 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0044271 Not Cancer Driver No 155 0.122 939 118 0.126 0
SEPSECS SEPSECS Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase chr4 GO:0044271 Not Cancer Driver No 47 0.094 22 7 0.318 3
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0044271 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SGMS1 SGMS1 Q86VZ5 Phosphatidylcholine:ceramide cholinephosphotransferase 1 chr10 GO:0044271 Not Cancer Driver No 85 0.206 37 8 0.216 0
SGMS2 SGMS2 Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 chr4 GO:0044271 Not Cancer Driver No 37 0.101 49 7 0.143 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0044271 Not Cancer Driver No 51 0.106 32 7 0.219 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0044271 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0044271 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0044271 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0044271 Not Cancer Driver No 55 0.1 32 3 0.094 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 GO:0044271 Not Cancer Driver No 22 0.071 34 2 0.059 17
SLC25A15 SLC25A15 Q9Y619 Mitochondrial ornithine transporter 1 chr13 GO:0044271 Not Cancer Driver No 33 0.11 0 0 0.0 14
SLC25A16 SLC25A16 P16260 Graves disease carrier protein chr10 GO:0044271 Not Cancer Driver No 37 0.111 9 0 0.0 0
SLC25A2 SLC25A2 Q9BXI2 Mitochondrial ornithine transporter 2 chr5 GO:0044271 Not Cancer Driver No 80 0.266 0 0 0.0 0
SLC26A1 SLC26A1 Q9H2B4 Sulfate anion transporter 1 chr4 GO:0044271 Not Cancer Driver No 54 0.077 86 7 0.081 2
SLC26A2 SLC26A2 P50443 Sulfate transporter chr5 GO:0044271 Not Cancer Driver No 71 0.096 41 3 0.073 9
SLC35B2 SLC35B2 Q8TB61 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 chr6 GO:0044271 Not Cancer Driver No 49 0.113 13 3 0.231 0
SLC35B3 SLC35B3 Q9H1N7 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 chr6 GO:0044271 Not Cancer Driver No 33 0.082 6 0 0.0 0
SLC5A8 SLC5A8 Q8N695 Sodium-coupled monocarboxylate transporter 1 chr12 GO:0044271 Not Cancer Driver No 156 0.256 33 10 0.303 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0044271 Not Cancer Driver No 150 0.242 31 8 0.258 2
SMN2_ENST00000380741 SMN2 Q16637 Survival motor neuron protein chr5 GO:0044271 Not Cancer Driver No 1 0.003 220 1 0.005 18
SMOX_ENST00000305958 SMOX Q9NWM0 Spermine oxidase chr20 GO:0044271 Not Cancer Driver No 79 0.142 164 23 0.14 0
SMS SMS P52788 Spermine synthase chrX GO:0044271 Not Cancer Driver No 46 0.126 28 6 0.214 5
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 GO:0044271 Not Cancer Driver No 36 0.098 158 16 0.101 0
SNAPC2 SNAPC2 Q13487 snRNA-activating protein complex subunit 2 chr19 GO:0044271 Not Cancer Driver No 33 0.099 260 24 0.092 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0044271 Not Cancer Driver No 30 0.073 99 2 0.02 0
SNAPC4 SNAPC4 Q5SXM2 snRNA-activating protein complex subunit 4 chr9 GO:0044271 Not Cancer Driver No 143 0.097 1094 96 0.088 0
SNAPC5_ENST00000395589 SNAPC5 O75971 snRNA-activating protein complex subunit 5 chr15 GO:0044271 Not Cancer Driver No 9 0.092 95 9 0.095 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0044271 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 GO:0044271 Not Cancer Driver No 71 0.196 220 40 0.182 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0044271 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0044271 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPIN1 SPIN1 Q9Y657 Spindlin-1 chr9 GO:0044271 Not Cancer Driver No 31 0.118 132 18 0.136 0
SPR SPR P35270 Sepiapterin reductase chr2 GO:0044271 Not Cancer Driver No 23 0.088 19 4 0.211 2
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0044271 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0044271 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:0044271 Not Cancer Driver No 72 0.128 9 2 0.222 5
SPTLC3 SPTLC3 Q9NUV7 Serine palmitoyltransferase 3 chr20 GO:0044271 Not Cancer Driver No 135 0.245 40 12 0.3 0
SPTSSA SPTSSA Q969W0 Serine palmitoyltransferase small subunit A chr14 GO:0044271 Not Cancer Driver No 9 0.127 0 0 0.0 0
SPTSSB_ENST00000620149 SPTSSB Q8NFR3 Serine palmitoyltransferase small subunit B chr3 GO:0044271 Not Cancer Driver No 15 0.197 0 0 0.0 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0044271 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRM SRM P19623 Spermidine synthase chr1 GO:0044271 Not Cancer Driver No 27 0.089 23 0 0.0 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0044271 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0044271 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0044271 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0044271 Not Cancer Driver No 8 0.041 8 0 0.0 0
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0044271 Not Cancer Driver No 51 0.15 6 0 0.0 0
ST3GAL2 ST3GAL2 Q16842 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 chr16 GO:0044271 Not Cancer Driver No 47 0.134 10 0 0.0 0
ST3GAL3_ENST00000644195 ST3GAL3 Q11203 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase chr1 GO:0044271 Not Cancer Driver No 49 0.131 6 2 0.333 3
ST3GAL5 ST3GAL5 Q9UNP4 Lactosylceramide alpha-2,3-sialyltransferase chr2 GO:0044271 Not Cancer Driver No 43 0.103 27 0 0.0 0
ST6GALNAC3 ST6GALNAC3 Q8NDV1 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 chr1 GO:0044271 Not Cancer Driver No 104 0.341 0 0 0.0 0
ST6GALNAC4 ST6GALNAC4 Q9H4F1 Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase chr9 GO:0044271 Not Cancer Driver No 34 0.113 0 0 0.0 0
ST6GALNAC5 ST6GALNAC5 Q9BVH7 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 chr1 GO:0044271 Not Cancer Driver No 91 0.271 94 25 0.266 0
ST6GALNAC6_ENST00000373146 ST6GALNAC6 Q969X2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 chr9 GO:0044271 Not Cancer Driver No 44 0.132 86 13 0.151 0
ST8SIA2 ST8SIA2 Q92186 Alpha-2,8-sialyltransferase 8B chr15 GO:0044271 Not Cancer Driver No 84 0.224 38 8 0.211 0
ST8SIA3 ST8SIA3 O43173 Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase chr18 GO:0044271 Not Cancer Driver No 109 0.287 0 0 0.0 0
ST8SIA4 ST8SIA4 Q92187 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase chr5 GO:0044271 Not Cancer Driver No 95 0.265 5 1 0.2 0
ST8SIA6 ST8SIA6 P61647 Alpha-2,8-sialyltransferase 8F chr10 GO:0044271 Not Cancer Driver No 71 0.178 45 7 0.156 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0044271 Census, Compendium Yes 110 0.143 152 15 0.099 19
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0044271 Not Cancer Driver No 40 0.112 117 9 0.077 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 GO:0044271 Not Cancer Driver No 13 0.102 108 6 0.056 0
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 GO:0044271 Not Cancer Driver No 51 0.11 46 6 0.13 3
SULT1A2 SULT1A2 P50226 Sulfotransferase 1A2 chr16 GO:0044271 Not Cancer Driver No 46 0.156 3 0 0.0 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0044271 Not Cancer Driver No 222 0.129 761 107 0.141 0
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0044271 Not Cancer Driver No 207 0.212 602 124 0.206 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0044271 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF11 TAF11 Q15544 Transcription initiation factor TFIID subunit 11 chr6 GO:0044271 Not Cancer Driver No 22 0.104 137 16 0.117 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:0044271 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF13 TAF13 Q15543 Transcription initiation factor TFIID subunit 13 chr1 GO:0044271 Not Cancer Driver No 11 0.089 34 3 0.088 2
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0044271 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0044271 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0044271 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF3 TAF3 Q5VWG9 Transcription initiation factor TFIID subunit 3 chr10 GO:0044271 Not Cancer Driver No 113 0.122 750 90 0.12 0
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0044271 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF4B_ENST00000269142 TAF4B Q92750 Transcription initiation factor TFIID subunit 4B chr18 GO:0044271 Not Cancer Driver No 86 0.1 482 46 0.095 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:0044271 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0044271 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0044271 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0044271 Not Cancer Driver No 35 0.113 255 30 0.118 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0044271 Not Cancer Driver No 25 0.095 203 19 0.094 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0044271 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0044271 Not Cancer Driver No 27 0.145 6 0 0.0 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 GO:0044271 Not Cancer Driver No 41 0.133 0 0 0.0 1
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0044271 Not Cancer Driver No 37 0.103 26 5 0.192 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0044271 Census Yes 110 0.097 212 16 0.075 31
TEX12 TEX12 Q9BXU0 Testis-expressed protein 12 chr11 GO:0044271 Not Cancer Driver No 10 0.081 35 3 0.086 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0044271 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFB1M TFB1M Q8WVM0 Dimethyladenosine transferase 1, mitochondrial chr6 GO:0044271 Not Cancer Driver No 50 0.145 26 3 0.115 0
TFB2M TFB2M Q9H5Q4 Dimethyladenosine transferase 2, mitochondrial chr1 GO:0044271 Not Cancer Driver No 60 0.152 36 6 0.167 0
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 GO:0044271 Not Cancer Driver No 68 0.135 169 23 0.136 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0044271 Not Cancer Driver No 63 0.152 47 8 0.17 3
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0044271 Not Cancer Driver No 61 0.116 149 21 0.141 38
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0044271 Not Cancer Driver No 87 0.189 113 28 0.248 33
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 GO:0044271 Not Cancer Driver No 26 0.111 13 4 0.308 0
TK2 TK2 O00142 Thymidine kinase 2, mitochondrial chr16 GO:0044271 Not Cancer Driver No 23 0.087 44 3 0.068 11
TMLHE TMLHE Q9NVH6 Trimethyllysine dioxygenase, mitochondrial chrX GO:0044271 Not Cancer Driver No 49 0.116 4 0 0.0 1
TOPAZ1 TOPAZ1 Q8N9V7 Protein TOPAZ1 chr3 GO:0044271 Not Cancer Driver No 110 0.065 814 61 0.075 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0044271 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPH1 TPH1 P17752 Tryptophan 5-hydroxylase 1 chr11 GO:0044271 Not Cancer Driver No 80 0.18 14 3 0.214 0
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0044271 Not Cancer Driver No 118 0.241 55 17 0.309 1
TPK1 TPK1 Q9H3S4 Thiamin pyrophosphokinase 1 chr7 GO:0044271 Not Cancer Driver No 56 0.23 0 0 0.0 3
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0044271 Not Cancer Driver No 26 0.083 98 10 0.102 18
TSTA3_ENST00000529064 GFUS Q13630 GDP-L-fucose synthase chr8 GO:0044271 Not Cancer Driver No 38 0.118 19 2 0.105 0
TTF1 TTF1 Q15361 Transcription termination factor 1 chr9 GO:0044271 Not Cancer Driver No 105 0.116 535 59 0.11 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0044271 Not Cancer Driver No 118 0.102 550 50 0.091 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0044271 Not Cancer Driver No 22 0.07 41 0 0.0 0
UAP1 UAP1 Q16222 UDP-N-acetylhexosamine pyrophosphorylase chr1 GO:0044271 Not Cancer Driver No 67 0.128 78 7 0.09 0
UAP1L1 UAP1L1 Q3KQV9 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 chr9 GO:0044271 Not Cancer Driver No 36 0.071 120 5 0.042 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0044271 Not Cancer Driver No 100 0.131 567 77 0.136 1
UCK1_ENST00000372215 UCK1 Q9HA47 Uridine-cytidine kinase 1 chr9 GO:0044271 Not Cancer Driver No 35 0.126 70 3 0.043 0
UCK2 UCK2 Q9BZX2 Uridine-cytidine kinase 2 chr1 GO:0044271 Not Cancer Driver No 43 0.165 61 10 0.164 0
UCKL1 UCKL1 Q9NWZ5 Uridine-cytidine kinase-like 1 chr20 GO:0044271 Not Cancer Driver No 54 0.099 134 15 0.112 0
UGCG UGCG Q16739 Ceramide glucosyltransferase chr9 GO:0044271 Not Cancer Driver No 37 0.094 0 0 0.0 0
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 GO:0044271 Not Cancer Driver No 54 0.109 39 4 0.103 5
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 GO:0044271 Not Cancer Driver No 107 0.198 18 2 0.111 0
UMPS UMPS P11172 Uridine 5'-monophosphate synthase chr3 GO:0044271 Not Cancer Driver No 58 0.121 18 2 0.111 3
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0044271 Not Cancer Driver No 47 0.152 13 3 0.231 0
UPP2_ENST00000005756 UPP2 O95045 Uridine phosphorylase 2 chr2 GO:0044271 Not Cancer Driver No 55 0.174 5 1 0.2 0
UPRT UPRT Q96BW1 Uracil phosphoribosyltransferase homolog chrX GO:0044271 Not Cancer Driver No 64 0.207 76 15 0.197 0
UROD UROD P06132 Uroporphyrinogen decarboxylase chr1 GO:0044271 Not Cancer Driver No 32 0.087 33 2 0.061 39
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0044271 Not Cancer Driver No 34 0.128 7 0 0.0 21
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0044271 Not Cancer Driver No 107 0.098 578 55 0.095 0
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 GO:0044271 Not Cancer Driver No 70 0.167 69 9 0.13 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 GO:0044271 Not Cancer Driver No 24 0.096 184 14 0.076 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0044271 Not Cancer Driver No 64 0.15 102 16 0.157 14
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0044271 Not Cancer Driver No 129 0.136 427 63 0.148 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0044271 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0044271 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZNRD1 POLR1H Q9P1U0 DNA-directed RNA polymerase I subunit RPA12 chr6 GO:0044271 Not Cancer Driver No 6 0.048 14 1 0.071 0