Total number of protein in "GO:0043433" GO term: 92
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRG3 | ADGRG3 | Q86Y34 | Adhesion G protein-coupled receptor G3 | chr16 | GO:0043433 | Not Cancer Driver | No | 87 | 0.158 | 42 | 5 | 0.119 | 0 |
| BHLHE40 | BHLHE40 | O14503 | Class E basic helix-loop-helix protein 40 | chr3 | GO:0043433 | Not Cancer Driver | No | 52 | 0.126 | 242 | 31 | 0.128 | 0 |
| BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0043433 | Not Cancer Driver | No | 80 | 0.132 | 45 | 4 | 0.089 | 0 |
| CCDC22 | CCDC22 | O60826 | Coiled-coil domain-containing protein 22 | chrX | GO:0043433 | Not Cancer Driver | No | 62 | 0.099 | 243 | 18 | 0.074 | 2 |
| CEBPG_ENST00000585933 | CEBPG | P53567 | CCAAT/enhancer-binding protein gamma | chr19 | GO:0043433 | Not Cancer Driver | No | 13 | 0.087 | 141 | 12 | 0.085 | 0 |
| CTNNBIP1_ENST00000377258 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0043433 | Not Cancer Driver | No | 8 | 0.099 | 64 | 7 | 0.109 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0043433 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0043433 | Not Cancer Driver | No | 49 | 0.112 | 272 | 23 | 0.085 | 0 |
| EGLN1 | EGLN1 | Q9GZT9 | Egl nine homolog 1 | chr1 | GO:0043433 | Not Cancer Driver | No | 35 | 0.082 | 206 | 8 | 0.039 | 2 |
| EIF2AK4 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0043433 | Not Cancer Driver | No | 156 | 0.095 | 494 | 44 | 0.089 | 2 |
| EOMES_ENST00000295743 | EOMES | O95936 | Eomesodermin homolog | chr3 | GO:0043433 | Not Cancer Driver | No | 82 | 0.12 | 436 | 50 | 0.115 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0043433 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0043433 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0043433 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0043433 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FOXA2_ENST00000377115 | FOXA2 | Q9Y261 | Hepatocyte nuclear factor 3-beta | chr20 | GO:0043433 | Compendium | Yes | 70 | 0.153 | 258 | 34 | 0.132 | 0 |
| FOXH1 | FOXH1 | O75593 | Forkhead box protein H1 | chr8 | GO:0043433 | Not Cancer Driver | No | 47 | 0.129 | 215 | 25 | 0.116 | 0 |
| FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0043433 | Not Cancer Driver | No | 38 | 0.088 | 186 | 16 | 0.086 | 10 |
| FOXS1 | FOXS1 | O43638 | Forkhead box protein S1 | chr20 | GO:0043433 | Not Cancer Driver | No | 67 | 0.203 | 226 | 41 | 0.181 | 0 |
| FZD6 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:0043433 | Not Cancer Driver | No | 95 | 0.135 | 172 | 15 | 0.087 | 1 |
| G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | GO:0043433 | Not Cancer Driver | No | 64 | 0.133 | 384 | 53 | 0.138 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0043433 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GLIS2 | GLIS2 | Q9BZE0 | Zinc finger protein GLIS2 | chr16 | GO:0043433 | Not Cancer Driver | No | 42 | 0.08 | 300 | 25 | 0.083 | 0 |
| HAND1 | HAND1 | O96004 | Heart- and neural crest derivatives-expressed protein 1 | chr5 | GO:0043433 | Not Cancer Driver | No | 35 | 0.163 | 166 | 29 | 0.175 | 0 |
| HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0043433 | Not Cancer Driver | No | 47 | 0.217 | 124 | 29 | 0.234 | 0 |
| HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0043433 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | GO:0043433 | Not Cancer Driver | No | 182 | 0.168 | 749 | 132 | 0.176 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0043433 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HES6 | HES6 | Q96HZ4 | Transcription cofactor HES-6 | chr2 | GO:0043433 | Not Cancer Driver | No | 10 | 0.045 | 130 | 6 | 0.046 | 0 |
| HEYL | HEYL | Q9NQ87 | Hairy/enhancer-of-split related with YRPW motif-like protein | chr1 | GO:0043433 | Not Cancer Driver | No | 44 | 0.134 | 198 | 19 | 0.096 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0043433 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:0043433 | Not Cancer Driver | No | 20 | 0.129 | 17 | 6 | 0.353 | 0 |
| ID2_ENST00000396290 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0043433 | Not Cancer Driver | No | 14 | 0.104 | 52 | 7 | 0.135 | 0 |
| ID3 | ID3 | Q02535 | DNA-binding protein inhibitor ID-3 | chr1 | GO:0043433 | Census, Compendium | Yes | 14 | 0.118 | 34 | 4 | 0.118 | 0 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0043433 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0043433 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0043433 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0043433 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MAP3K10 | MAP3K10 | Q02779 | Mitogen-activated protein kinase kinase kinase 10 | chr19 | GO:0043433 | Not Cancer Driver | No | 112 | 0.117 | 589 | 62 | 0.105 | 0 |
| MDFI | MDFI | Q99750 | MyoD family inhibitor | chr6 | GO:0043433 | Not Cancer Driver | No | 25 | 0.102 | 152 | 15 | 0.099 | 0 |
| MED13 | MED13 | Q9UHV7 | Mediator of RNA polymerase II transcription subunit 13 | chr17 | GO:0043433 | Not Cancer Driver | No | 288 | 0.132 | 905 | 127 | 0.14 | 3 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0043433 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0043433 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
| NDN | NDN | Q99608 | Necdin | chr15 | GO:0043433 | Not Cancer Driver | No | 123 | 0.383 | 117 | 42 | 0.359 | 0 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0043433 | Compendium | Yes | 37 | 0.117 | 102 | 9 | 0.088 | 1 |
| NFKBIB | NFKBIB | Q15653 | NF-kappa-B inhibitor beta | chr19 | GO:0043433 | Not Cancer Driver | No | 42 | 0.118 | 223 | 29 | 0.13 | 0 |
| NFKBIE | NFKBIE | O00221 | NF-kappa-B inhibitor epsilon | chr6 | GO:0043433 | Census, Compendium | Yes | 41 | 0.082 | 284 | 16 | 0.056 | 0 |
| NR0B1 | NR0B1 | P51843 | Nuclear receptor subfamily 0 group B member 1 | chrX | GO:0043433 | Not Cancer Driver | No | 106 | 0.226 | 97 | 18 | 0.186 | 18 |
| NR0B2 | NR0B2 | Q15466 | Nuclear receptor subfamily 0 group B member 2 | chr1 | GO:0043433 | Not Cancer Driver | No | 35 | 0.136 | 10 | 2 | 0.2 | 0 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0043433 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0043433 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PEX14 | PEX14 | O75381 | Peroxisomal membrane protein PEX14 | chr1 | GO:0043433 | Not Cancer Driver | No | 38 | 0.101 | 266 | 28 | 0.105 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0043433 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PIM1 | PIM1 | P11309 | Serine/threonine-protein kinase pim-1 | chr6 | GO:0043433 | Census, Compendium | Yes | 71 | 0.227 | 27 | 8 | 0.296 | 0 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0043433 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0043433 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PLA2G10 | PLA2G10 | O15496 | Group 10 secretory phospholipase A2 | chr16 | GO:0043433 | Not Cancer Driver | No | 5 | 0.03 | 0 | 0 | 0.0 | 0 |
| POU4F2 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0043433 | Not Cancer Driver | No | 130 | 0.318 | 308 | 87 | 0.282 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0043433 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PROX1 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0043433 | Not Cancer Driver | No | 182 | 0.247 | 537 | 141 | 0.263 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0043433 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0043433 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| PURA | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0043433 | Not Cancer Driver | No | 22 | 0.068 | 188 | 10 | 0.053 | 6 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0043433 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| RLIM_ENST00000349225 | RLIM | Q9NVW2 | E3 ubiquitin-protein ligase RLIM | chrX | GO:0043433 | Not Cancer Driver | No | 106 | 0.17 | 545 | 94 | 0.172 | 4 |
| RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | GO:0043433 | Not Cancer Driver | No | 40 | 0.119 | 203 | 22 | 0.108 | 0 |
| SFRP4 | SFRP4 | Q6FHJ7 | Secreted frizzled-related protein 4 | chr7 | GO:0043433 | Census | Yes | 81 | 0.234 | 68 | 22 | 0.324 | 0 |
| SFRP5 | SFRP5 | Q5T4F7 | Secreted frizzled-related protein 5 | chr10 | GO:0043433 | Not Cancer Driver | No | 26 | 0.082 | 7 | 3 | 0.429 | 0 |
| SIGIRR_ENST00000397632 | SIGIRR | Q6IA17 | Single Ig IL-1-related receptor | chr11 | GO:0043433 | Not Cancer Driver | No | 27 | 0.066 | 85 | 4 | 0.047 | 0 |
| SIK1 | SIK1 | P57059 | Serine/threonine-protein kinase SIK1 | chr21 | GO:0043433 | Not Cancer Driver | No | 80 | 0.102 | 330 | 30 | 0.091 | 3 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0043433 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0043433 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | GO:0043433 | Not Cancer Driver | No | 136 | 0.155 | 680 | 101 | 0.149 | 0 |
| SRI | SRI | P30626 | Sorcin | chr7 | GO:0043433 | Not Cancer Driver | No | 15 | 0.076 | 32 | 2 | 0.062 | 0 |
| SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0043433 | Census | Yes | 55 | 0.114 | 199 | 19 | 0.095 | 2 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0043433 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0043433 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TAF3 | TAF3 | Q5VWG9 | Transcription initiation factor TFIID subunit 3 | chr10 | GO:0043433 | Not Cancer Driver | No | 113 | 0.122 | 750 | 90 | 0.12 | 0 |
| TBX6 | TBX6 | O95947 | T-box transcription factor TBX6 | chr16 | GO:0043433 | Not Cancer Driver | No | 44 | 0.101 | 253 | 25 | 0.099 | 0 |
| TBXT | TBXT | O15178 | T-box transcription factor T | chr6 | GO:0043433 | Not Cancer Driver | No | 110 | 0.253 | 253 | 69 | 0.273 | 1 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0043433 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TFDP1 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | GO:0043433 | Not Cancer Driver | No | 82 | 0.2 | 245 | 47 | 0.192 | 0 |
| TFDP3 | TFDP3 | Q5H9I0 | Transcription factor Dp family member 3 | chrX | GO:0043433 | Not Cancer Driver | No | 84 | 0.207 | 186 | 42 | 0.226 | 0 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0043433 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TNFRSF4 | TNFRSF4 | P43489 | Tumor necrosis factor receptor superfamily member 4 | chr1 | GO:0043433 | Not Cancer Driver | No | 30 | 0.108 | 94 | 14 | 0.149 | 1 |
| TNFSF4 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0043433 | Not Cancer Driver | No | 28 | 0.153 | 1 | 0 | 0.0 | 0 |
| TRIB1 | TRIB1 | Q96RU8 | Tribbles homolog 1 | chr8 | GO:0043433 | Not Cancer Driver | No | 47 | 0.126 | 91 | 5 | 0.055 | 0 |
| TWIST1 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0043433 | Not Cancer Driver | No | 23 | 0.114 | 132 | 11 | 0.083 | 7 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | GO:0043433 | Not Cancer Driver | No | 105 | 0.118 | 203 | 10 | 0.049 | 39 |
| WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0043433 | Not Cancer Driver | No | 112 | 0.129 | 422 | 57 | 0.135 | 0 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0043433 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
| ZNF431 | ZNF431 | Q8TF32 | Zinc finger protein 431 | chr19 | GO:0043433 | Not Cancer Driver | No | 96 | 0.167 | 54 | 6 | 0.111 | 0 |