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Total number of protein in "GO:0043409" GO term:  136

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0043409 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043409 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0043409 Not Cancer Driver No 104 0.129 68 5 0.074 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0043409 Not Cancer Driver No 39 0.16 92 21 0.228 1
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0043409 Not Cancer Driver No 36 0.118 87 9 0.103 0
AMBP AMBP P02760 Protein AMBP chr9 GO:0043409 Not Cancer Driver No 57 0.162 61 15 0.246 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 GO:0043409 Not Cancer Driver No 415 0.14 1858 256 0.138 1
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0043409 Not Cancer Driver No 23 0.127 118 14 0.119 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0043409 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:0043409 Not Cancer Driver No 19 0.08 101 5 0.05 0
C3orf33 C3orf33 Q6P1S2 Protein C3orf33 chr3 GO:0043409 Not Cancer Driver No 30 0.102 23 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0043409 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0043409 Not Cancer Driver No 27 0.179 0 0 0.0 25
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0043409 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0043409 Not Cancer Driver No 76 0.159 23 6 0.261 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0043409 Not Cancer Driver No 72 0.13 269 43 0.16 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0043409 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0043409 Not Cancer Driver No 41 0.091 18 1 0.056 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0043409 Census, Compendium Yes 116 0.121 213 31 0.146 3
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0043409 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043409 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0043409 Not Cancer Driver No 163 0.195 598 127 0.212 1
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0043409 Not Cancer Driver No 102 0.114 485 61 0.126 4
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0043409 Not Cancer Driver No 120 0.133 460 67 0.146 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0043409 Not Cancer Driver No 37 0.093 153 16 0.105 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0043409 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0043409 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0043409 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 GO:0043409 Not Cancer Driver No 45 0.227 16 1 0.062 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0043409 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0043409 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 GO:0043409 Not Cancer Driver No 24 0.076 23 3 0.13 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:0043409 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP27_ENST00000271385 STYXL2 Q5VZP5 Serine/threonine/tyrosine-interacting-like protein 2 chr1 GO:0043409 Not Cancer Driver No 330 0.285 864 257 0.297 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0043409 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:0043409 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP5 DUSP5 Q16690 Dual specificity protein phosphatase 5 chr10 GO:0043409 Not Cancer Driver No 58 0.151 36 4 0.111 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0043409 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP7 DUSP7 Q16829 Dual specificity protein phosphatase 7 chr3 GO:0043409 Not Cancer Driver No 40 0.095 139 5 0.036 0
DUSP8_ENST00000331588 DUSP8 Q13202 Dual specificity protein phosphatase 8 chr11 GO:0043409 Not Cancer Driver No 40 0.064 338 11 0.033 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0043409 Not Cancer Driver No 40 0.104 109 12 0.11 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0043409 Not Cancer Driver No 29 0.141 46 5 0.109 0
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 GO:0043409 Not Cancer Driver No 181 0.131 835 130 0.156 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0043409 Not Cancer Driver No 125 0.123 669 69 0.103 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0043409 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0043409 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0043409 Not Cancer Driver No 55 0.119 297 37 0.125 0
EZR EZR P15311 Ezrin chr6 GO:0043409 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0043409 Not Cancer Driver No 55 0.139 7 2 0.286 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0043409 Compendium Yes 122 0.174 22 3 0.136 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:0043409 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0043409 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0043409 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0043409 Census, Compendium Yes 81 0.124 584 75 0.128 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0043409 Not Cancer Driver No 92 0.155 166 27 0.163 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0043409 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0043409 Not Cancer Driver No 29 0.089 319 26 0.082 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0043409 Not Cancer Driver No 32 0.152 0 0 0.0 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0043409 Not Cancer Driver No 65 0.152 61 8 0.131 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0043409 Not Cancer Driver No 128 0.105 559 51 0.091 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:0043409 Not Cancer Driver No 51 0.15 193 28 0.145 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0043409 Not Cancer Driver No 183 0.134 265 37 0.14 6
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0043409 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0043409 Not Cancer Driver No 26 0.13 58 11 0.19 0
KLHL31 KLHL31 Q9H511 Kelch-like protein 31 chr6 GO:0043409 Not Cancer Driver No 69 0.109 32 1 0.031 0
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:0043409 Not Cancer Driver No 44 0.087 211 4 0.019 2
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0043409 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0043409 Not Cancer Driver No 162 0.362 277 115 0.415 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0043409 Not Cancer Driver No 30 0.207 1 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0043409 Census Yes 95 0.186 84 12 0.143 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0043409 Not Cancer Driver No 79 0.111 444 40 0.09 1
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0043409 Not Cancer Driver No 40 0.1 179 10 0.056 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:0043409 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEN1 MEN1 O00255 Menin chr11 GO:0043409 Census, Compendium Yes 73 0.119 228 15 0.066 90
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043409 Census, Compendium Yes 80 0.182 299 46 0.154 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0043409 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:0043409 Not Cancer Driver No 45 0.121 111 8 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0043409 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0043409 Census, Compendium Yes 69 0.116 252 26 0.103 16
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0043409 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0043409 Not Cancer Driver No 106 0.119 203 28 0.138 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0043409 Not Cancer Driver No 32 0.212 71 14 0.197 1
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0043409 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0043409 Not Cancer Driver No 42 0.102 82 11 0.134 7
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0043409 Not Cancer Driver No 23 0.071 92 6 0.065 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0043409 Not Cancer Driver No 57 0.122 187 32 0.171 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 GO:0043409 Not Cancer Driver No 23 0.123 76 13 0.171 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0043409 Census Yes 160 0.124 948 116 0.122 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0043409 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0043409 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0043409 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0043409 Not Cancer Driver No 57 0.098 99 13 0.131 23
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0043409 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0043409 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0043409 Census, Compendium Yes 179 0.304 0 0 0.0 4
PRDM15 PRDM15 P57071 PR domain zinc finger protein 15 chr21 GO:0043409 Not Cancer Driver No 159 0.106 800 75 0.094 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0043409 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSCA PSCA O43653 Prostate stem cell antigen chr8 GO:0043409 Not Cancer Driver No 9 0.079 0 0 0.0 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0043409 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0043409 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0043409 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0043409 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0043409 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0043409 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0043409 Not Cancer Driver No 172 0.262 73 28 0.384 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0043409 Not Cancer Driver No 101 0.13 106 16 0.151 4
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0043409 Not Cancer Driver No 73 0.1 413 30 0.073 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0043409 Not Cancer Driver No 57 0.101 309 37 0.12 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 GO:0043409 Not Cancer Driver No 41 0.102 102 10 0.098 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0043409 Not Cancer Driver No 180 0.242 136 36 0.265 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0043409 Not Cancer Driver No 136 0.132 456 72 0.158 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0043409 Not Cancer Driver No 142 0.364 47 28 0.596 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0043409 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0043409 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0043409 Not Cancer Driver No 151 0.207 455 101 0.222 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0043409 Census, Compendium Yes 96 0.19 281 51 0.181 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0043409 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0043409 Census, Compendium Yes 198 0.359 195 17 0.087 8
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0043409 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0043409 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:0043409 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0043409 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0043409 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY3 SPRY3 O43610 Protein sprouty homolog 3 chrX GO:0043409 Not Cancer Driver No 96 0.333 135 40 0.296 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0043409 Not Cancer Driver No 34 0.114 134 20 0.149 7
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:0043409 Not Cancer Driver No 27 0.186 12 4 0.333 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0043409 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0043409 Not Cancer Driver No 58 0.13 192 32 0.167 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0043409 Not Cancer Driver No 43 0.204 3 1 0.333 5
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0043409 Not Cancer Driver No 292 0.348 0 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0043409 Not Cancer Driver No 85 0.134 625 83 0.133 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0043409 Not Cancer Driver No 43 0.187 27 2 0.074 1
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0043409 Not Cancer Driver No 65 0.137 180 18 0.1 0
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0043409 Census, Compendium Yes 223 0.097 1868 167 0.089 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0043409 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0043409 Not Cancer Driver No 114 0.201 91 19 0.209 0