Total number of protein in "GO:0043408" GO term: 211
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0043408 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | GO:0043408 | Not Cancer Driver | No | 104 | 0.129 | 68 | 5 | 0.074 | 0 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0043408 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0043408 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AIDA | AIDA | Q96BJ3 | Axin interactor, dorsalization-associated protein | chr1 | GO:0043408 | Not Cancer Driver | No | 36 | 0.118 | 87 | 9 | 0.103 | 0 |
| ALKAL1 | ALKAL1 | Q6UXT8 | ALK and LTK ligand 1 | chr8 | GO:0043408 | Not Cancer Driver | No | 18 | 0.14 | 49 | 3 | 0.061 | 0 |
| ALKAL2 | ALKAL2 | Q6UX46 | ALK and LTK ligand 2 | chr2 | GO:0043408 | Not Cancer Driver | No | 7 | 0.046 | 31 | 0 | 0.0 | 0 |
| AMBP | AMBP | P02760 | Protein AMBP | chr9 | GO:0043408 | Not Cancer Driver | No | 57 | 0.162 | 61 | 15 | 0.246 | 0 |
| ARHGEF5 | ARHGEF5 | Q12774 | Rho guanine nucleotide exchange factor 5 | chr7 | GO:0043408 | Not Cancer Driver | No | 170 | 0.106 | 1141 | 127 | 0.111 | 0 |
| ATF3_ENST00000366987 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | GO:0043408 | Not Cancer Driver | No | 23 | 0.127 | 118 | 14 | 0.119 | 0 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | GO:0043408 | Not Cancer Driver | No | 56 | 0.16 | 0 | 0 | 0.0 | 2 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0043408 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0043408 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0043408 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BTN2A2 | BTN2A2 | Q8WVV5 | Butyrophilin subfamily 2 member A2 | chr6 | GO:0043408 | Not Cancer Driver | No | 92 | 0.176 | 24 | 2 | 0.083 | 0 |
| C1QL4 | C1QL4 | Q86Z23 | Complement C1q-like protein 4 | chr12 | GO:0043408 | Not Cancer Driver | No | 19 | 0.08 | 101 | 5 | 0.05 | 0 |
| C3orf33 | C3orf33 | Q6P1S2 | Protein C3orf33 | chr3 | GO:0043408 | Not Cancer Driver | No | 30 | 0.102 | 23 | 0 | 0.0 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0043408 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0043408 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CHRNA10 | CHRNA10 | Q9GZZ6 | Neuronal acetylcholine receptor subunit alpha-10 | chr11 | GO:0043408 | Not Cancer Driver | No | 65 | 0.144 | 34 | 5 | 0.147 | 0 |
| CHRNA9 | CHRNA9 | Q9UGM1 | Neuronal acetylcholine receptor subunit alpha-9 | chr4 | GO:0043408 | Not Cancer Driver | No | 76 | 0.159 | 23 | 6 | 0.261 | 0 |
| CNKSR3 | CNKSR3 | Q6P9H4 | Connector enhancer of kinase suppressor of ras 3 | chr6 | GO:0043408 | Not Cancer Driver | No | 72 | 0.13 | 269 | 43 | 0.16 | 0 |
| CRYBA1 | CRYBA1 | P05813 | Beta-crystallin A3 | chr17 | GO:0043408 | Not Cancer Driver | No | 29 | 0.135 | 52 | 11 | 0.212 | 0 |
| CSK_ENST00000439220 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | GO:0043408 | Not Cancer Driver | No | 41 | 0.091 | 18 | 1 | 0.056 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0043408 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0043408 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0043408 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0043408 | Not Cancer Driver | No | 163 | 0.195 | 598 | 127 | 0.212 | 1 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0043408 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0043408 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0043408 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| DUPD1 | DUSP29 | Q68J44 | Dual specificity phosphatase 29 | chr10 | GO:0043408 | Not Cancer Driver | No | 47 | 0.214 | 55 | 7 | 0.127 | 0 |
| DUSP1 | DUSP1 | P28562 | Dual specificity protein phosphatase 1 | chr5 | GO:0043408 | Not Cancer Driver | No | 31 | 0.084 | 7 | 0 | 0.0 | 0 |
| DUSP10 | DUSP10 | Q9Y6W6 | Dual specificity protein phosphatase 10 | chr1 | GO:0043408 | Not Cancer Driver | No | 81 | 0.168 | 135 | 24 | 0.178 | 0 |
| DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | GO:0043408 | Compendium | Yes | 70 | 0.105 | 273 | 34 | 0.125 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0043408 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
| DUSP26 | DUSP26 | Q9BV47 | Dual specificity protein phosphatase 26 | chr8 | GO:0043408 | Not Cancer Driver | No | 56 | 0.265 | 14 | 6 | 0.429 | 0 |
| DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:0043408 | Not Cancer Driver | No | 21 | 0.114 | 4 | 1 | 0.25 | 0 |
| DUSP4 | DUSP4 | Q13115 | Dual specificity protein phosphatase 4 | chr8 | GO:0043408 | Not Cancer Driver | No | 43 | 0.109 | 63 | 9 | 0.143 | 0 |
| DUSP6 | DUSP6 | Q16828 | Dual specificity protein phosphatase 6 | chr12 | GO:0043408 | Not Cancer Driver | No | 43 | 0.113 | 39 | 3 | 0.077 | 4 |
| DUSP9 | DUSP9 | Q99956 | Dual specificity protein phosphatase 9 | chrX | GO:0043408 | Not Cancer Driver | No | 40 | 0.104 | 109 | 12 | 0.11 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0043408 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0043408 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0043408 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EIF3A | EIF3A | Q14152 | Eukaryotic translation initiation factor 3 subunit A | chr10 | GO:0043408 | Not Cancer Driver | No | 181 | 0.131 | 835 | 130 | 0.156 | 0 |
| EMC10 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | GO:0043408 | Not Cancer Driver | No | 25 | 0.095 | 109 | 15 | 0.138 | 0 |
| EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0043408 | Not Cancer Driver | No | 125 | 0.123 | 669 | 69 | 0.103 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0043408 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0043408 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0043408 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| ERN2 | ERN2 | Q76MJ5 | Serine/threonine-protein kinase/endoribonuclease IRE2 | chr16 | GO:0043408 | Not Cancer Driver | No | 192 | 0.207 | 213 | 45 | 0.211 | 0 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0043408 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| EZR | EZR | P15311 | Ezrin | chr6 | GO:0043408 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0043408 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| FBLN1 | FBLN1 | P23142 | Fibulin-1 | chr22 | GO:0043408 | Compendium | Yes | 122 | 0.174 | 22 | 3 | 0.136 | 0 |
| FGD2 | FGD2 | Q7Z6J4 | FYVE, RhoGEF and PH domain-containing protein 2 | chr6 | GO:0043408 | Not Cancer Driver | No | 113 | 0.173 | 158 | 26 | 0.165 | 0 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0043408 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| FGF23 | FGF23 | Q9GZV9 | Fibroblast growth factor 23 | chr12 | GO:0043408 | Not Cancer Driver | No | 84 | 0.335 | 97 | 51 | 0.526 | 7 |
| FKTN_ENST00000602661 | FKTN | O75072 | Ribitol-5-phosphate transferase FKTN | chr9 | GO:0043408 | Not Cancer Driver | No | 51 | 0.111 | 0 | 0 | 0.0 | 10 |
| FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0043408 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
| FOXM1_ENST00000359843 | FOXM1 | Q08050 | Forkhead box protein M1 | chr12 | GO:0043408 | Not Cancer Driver | No | 97 | 0.127 | 601 | 73 | 0.121 | 0 |
| FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0043408 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
| FZD10 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0043408 | Not Cancer Driver | No | 148 | 0.255 | 65 | 15 | 0.231 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0043408 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0043408 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| FZD8 | FZD8 | Q9H461 | Frizzled-8 | chr10 | GO:0043408 | Not Cancer Driver | No | 72 | 0.104 | 146 | 3 | 0.021 | 0 |
| GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0043408 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
| GADD45B | GADD45B | O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta | chr19 | GO:0043408 | Not Cancer Driver | No | 9 | 0.056 | 14 | 0 | 0.0 | 0 |
| GADD45G | GADD45G | O95257 | Growth arrest and DNA damage-inducible protein GADD45 gamma | chr9 | GO:0043408 | Not Cancer Driver | No | 13 | 0.082 | 20 | 2 | 0.1 | 0 |
| GBP1 | GBP1 | P32455 | Guanylate-binding protein 1 | chr1 | GO:0043408 | Not Cancer Driver | No | 92 | 0.155 | 166 | 27 | 0.163 | 0 |
| GDF6 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0043408 | Not Cancer Driver | No | 91 | 0.2 | 225 | 46 | 0.204 | 14 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0043408 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GPS2 | GPS2 | Q13227 | G protein pathway suppressor 2 | chr17 | GO:0043408 | Not Cancer Driver | No | 29 | 0.089 | 319 | 26 | 0.082 | 0 |
| GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0043408 | Not Cancer Driver | No | 28 | 0.129 | 10 | 1 | 0.1 | 0 |
| GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0043408 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
| HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0043408 | Not Cancer Driver | No | 47 | 0.217 | 124 | 29 | 0.234 | 0 |
| HDAC3 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | GO:0043408 | Not Cancer Driver | No | 65 | 0.152 | 61 | 8 | 0.131 | 0 |
| HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0043408 | Compendium | Yes | 233 | 0.32 | 43 | 16 | 0.372 | 0 |
| HIPK3 | HIPK3 | Q9H422 | Homeodomain-interacting protein kinase 3 | chr11 | GO:0043408 | Not Cancer Driver | No | 128 | 0.105 | 559 | 51 | 0.091 | 0 |
| HRH4 | HRH4 | Q9H3N8 | Histamine H4 receptor | chr18 | GO:0043408 | Not Cancer Driver | No | 72 | 0.185 | 1 | 1 | 1.0 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0043408 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0043408 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0043408 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0043408 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
| KL | KL | Q9UEF7 | Klotho | chr13 | GO:0043408 | Not Cancer Driver | No | 175 | 0.173 | 104 | 5 | 0.048 | 1 |
| KLB | KLB | Q86Z14 | Beta-klotho | chr4 | GO:0043408 | Not Cancer Driver | No | 139 | 0.133 | 6 | 1 | 0.167 | 0 |
| KLHL31 | KLHL31 | Q9H511 | Kelch-like protein 31 | chr6 | GO:0043408 | Not Cancer Driver | No | 69 | 0.109 | 32 | 1 | 0.031 | 0 |
| LBH | LBH | Q53QV2 | Protein LBH | chr2 | GO:0043408 | Not Cancer Driver | No | 15 | 0.143 | 72 | 10 | 0.139 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0043408 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0043408 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0043408 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| LMO3_ENST00000534946 | LMO3 | Q8TAP4 | LIM domain only protein 3 | chr12 | GO:0043408 | Not Cancer Driver | No | 30 | 0.207 | 1 | 0 | 0.0 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0043408 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0043408 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP3K10 | MAP3K10 | Q02779 | Mitogen-activated protein kinase kinase kinase 10 | chr19 | GO:0043408 | Not Cancer Driver | No | 112 | 0.117 | 589 | 62 | 0.105 | 0 |
| MAP3K11 | MAP3K11 | Q16584 | Mitogen-activated protein kinase kinase kinase 11 | chr11 | GO:0043408 | Not Cancer Driver | No | 97 | 0.115 | 466 | 54 | 0.116 | 0 |
| MAP3K12_ENST00000267079 | MAP3K12 | Q12852 | Mitogen-activated protein kinase kinase kinase 12 | chr12 | GO:0043408 | Not Cancer Driver | No | 120 | 0.14 | 481 | 64 | 0.133 | 0 |
| MAP3K13_ENST00000424227 | MAP3K13 | O43283 | Mitogen-activated protein kinase kinase kinase 13 | chr3 | GO:0043408 | Census | Yes | 157 | 0.163 | 593 | 91 | 0.153 | 0 |
| MAP3K3_ENST00000361733 | MAP3K3 | Q99759 | Mitogen-activated protein kinase kinase kinase 3 | chr17 | GO:0043408 | Not Cancer Driver | No | 74 | 0.118 | 355 | 44 | 0.124 | 0 |
| MAP3K4 | MAP3K4 | Q9Y6R4 | Mitogen-activated protein kinase kinase kinase 4 | chr6 | GO:0043408 | Not Cancer Driver | No | 261 | 0.162 | 520 | 86 | 0.165 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0043408 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0043408 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MAP4K2 | MAP4K2 | Q12851 | Mitogen-activated protein kinase kinase kinase kinase 2 | chr11 | GO:0043408 | Not Cancer Driver | No | 78 | 0.095 | 243 | 23 | 0.095 | 0 |
| MAP4K4_ENST00000347699 | MAP4K4 | O95819 | Mitogen-activated protein kinase kinase kinase kinase 4 | chr2 | GO:0043408 | Not Cancer Driver | No | 143 | 0.115 | 649 | 55 | 0.085 | 0 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0043408 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MARVELD3_ENST00000268485 | MARVELD3 | Q96A59 | MARVEL domain-containing protein 3 | chr16 | GO:0043408 | Not Cancer Driver | No | 40 | 0.1 | 179 | 10 | 0.056 | 0 |
| MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | GO:0043408 | Census, Compendium | Yes | 287 | 0.233 | 749 | 159 | 0.212 | 3 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0043408 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MFHAS1 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0043408 | Not Cancer Driver | No | 95 | 0.09 | 98 | 9 | 0.092 | 0 |
| MINK1 | MINK1 | Q8N4C8 | Misshapen-like kinase 1 | chr17 | GO:0043408 | Not Cancer Driver | No | 113 | 0.085 | 740 | 56 | 0.076 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0043408 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0043408 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0043408 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | GO:0043408 | Census, Compendium | Yes | 352 | 0.144 | 2347 | 340 | 0.145 | 0 |
| NDRG2 | NDRG2 | Q9UN36 | Protein NDRG2 | chr14 | GO:0043408 | Not Cancer Driver | No | 45 | 0.121 | 111 | 8 | 0.072 | 0 |
| NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0043408 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
| NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0043408 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
| NPFFR2 | NPFFR2 | Q9Y5X5 | Neuropeptide FF receptor 2 | chr4 | GO:0043408 | Not Cancer Driver | No | 154 | 0.295 | 57 | 20 | 0.351 | 0 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0043408 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| NRK | NRK | Q7Z2Y5 | Nik-related protein kinase | chrX | GO:0043408 | Compendium | Yes | 315 | 0.199 | 812 | 159 | 0.196 | 0 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0043408 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0043408 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0043408 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0043408 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0043408 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PAK4 | PAK4 | O96013 | Serine/threonine-protein kinase PAK 4 | chr19 | GO:0043408 | Not Cancer Driver | No | 58 | 0.098 | 340 | 33 | 0.097 | 0 |
| PAK5 | PAK5 | Q9P286 | Serine/threonine-protein kinase PAK 5 | chr20 | GO:0043408 | Not Cancer Driver | No | 226 | 0.314 | 407 | 123 | 0.302 | 0 |
| PAK6_ENST00000260404 | PAK6 | Q9NQU5 | Serine/threonine-protein kinase PAK 6 | chr15 | GO:0043408 | Not Cancer Driver | No | 82 | 0.12 | 398 | 52 | 0.131 | 0 |
| PBK_ENST00000301905 | PBK | Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | chr8 | GO:0043408 | Not Cancer Driver | No | 23 | 0.071 | 92 | 6 | 0.065 | 0 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0043408 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0043408 | Census | Yes | 160 | 0.124 | 948 | 116 | 0.122 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0043408 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PHLPP1 | PHLPP1 | O60346 | PH domain leucine-rich repeat-containing protein phosphatase 1 | chr18 | GO:0043408 | Not Cancer Driver | No | 134 | 0.078 | 744 | 29 | 0.039 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0043408 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0043408 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PJA2 | PJA2 | O43164 | E3 ubiquitin-protein ligase Praja-2 | chr5 | GO:0043408 | Not Cancer Driver | No | 80 | 0.113 | 598 | 66 | 0.11 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0043408 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PRDM11_ENST00000530656 | PRDM11 | Q9NQV5 | PR domain-containing protein 11 | chr11 | GO:0043408 | Not Cancer Driver | No | 93 | 0.182 | 236 | 40 | 0.169 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0043408 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | GO:0043408 | Not Cancer Driver | No | 50 | 0.135 | 18 | 1 | 0.056 | 0 |
| PSCA | PSCA | O43653 | Prostate stem cell antigen | chr8 | GO:0043408 | Not Cancer Driver | No | 9 | 0.079 | 0 | 0 | 0.0 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0043408 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0043408 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0043408 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0043408 | Not Cancer Driver | No | 57 | 0.137 | 120 | 14 | 0.117 | 0 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0043408 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0043408 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| PTPRR | PTPRR | Q15256 | Receptor-type tyrosine-protein phosphatase R | chr12 | GO:0043408 | Not Cancer Driver | No | 172 | 0.262 | 73 | 28 | 0.384 | 0 |
| QARS | QARS1 | P47897 | Glutamine--tRNA ligase | chr3 | GO:0043408 | Not Cancer Driver | No | 101 | 0.13 | 106 | 16 | 0.151 | 4 |
| RANBP9 | RANBP9 | Q96S59 | Ran-binding protein 9 | chr6 | GO:0043408 | Not Cancer Driver | No | 73 | 0.1 | 413 | 30 | 0.073 | 0 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0043408 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RELL1_ENST00000314117 | RELL1 | Q8IUW5 | RELT-like protein 1 | chr4 | GO:0043408 | Not Cancer Driver | No | 19 | 0.07 | 201 | 11 | 0.055 | 0 |
| RELL2 | RELL2 | Q8NC24 | RELT-like protein 2 | chr5 | GO:0043408 | Not Cancer Driver | No | 39 | 0.129 | 259 | 37 | 0.143 | 0 |
| REN | REN | P00797 | Renin | chr1 | GO:0043408 | Not Cancer Driver | No | 60 | 0.148 | 10 | 0 | 0.0 | 3 |
| RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0043408 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0043408 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0043408 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0043408 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| RPS6KA6_ENST00000262752 | RPS6KA6 | Q9UK32 | Ribosomal protein S6 kinase alpha-6 | chrX | GO:0043408 | Not Cancer Driver | No | 180 | 0.242 | 136 | 36 | 0.265 | 0 |
| SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:0043408 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
| SEMA6A_ENST00000510263 | SEMA6A | Q9H2E6 | Semaphorin-6A | chr5 | GO:0043408 | Not Cancer Driver | No | 136 | 0.132 | 456 | 72 | 0.158 | 0 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0043408 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0043408 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0043408 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0043408 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:0043408 | Census, Compendium | Yes | 96 | 0.19 | 281 | 51 | 0.181 | 0 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0043408 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0043408 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0043408 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0043408 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0043408 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
| SPRED2 | SPRED2 | Q7Z698 | Sprouty-related, EVH1 domain-containing protein 2 | chr2 | GO:0043408 | Not Cancer Driver | No | 73 | 0.175 | 228 | 43 | 0.189 | 0 |
| SPRED3_ENST00000586301 | SPRED3 | Q2MJR0 | Sprouty-related, EVH1 domain-containing protein 3 | chr19 | GO:0043408 | Not Cancer Driver | No | 31 | 0.076 | 207 | 15 | 0.072 | 0 |
| SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0043408 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0043408 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| SPRY3 | SPRY3 | O43610 | Protein sprouty homolog 3 | chrX | GO:0043408 | Not Cancer Driver | No | 96 | 0.333 | 135 | 40 | 0.296 | 0 |
| SPRY4_ENST00000434127 | SPRY4 | Q9C004 | Protein sprouty homolog 4 | chr5 | GO:0043408 | Not Cancer Driver | No | 34 | 0.114 | 134 | 20 | 0.149 | 7 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0043408 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0043408 | Not Cancer Driver | No | 70 | 0.143 | 241 | 32 | 0.133 | 0 |
| STK4 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0043408 | Not Cancer Driver | No | 70 | 0.144 | 231 | 30 | 0.13 | 0 |
| STK40_ENST00000373132 | STK40 | Q8N2I9 | Serine/threonine-protein kinase 40 | chr1 | GO:0043408 | Not Cancer Driver | No | 50 | 0.115 | 103 | 9 | 0.087 | 0 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0043408 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| SYNGAP1_ENST00000646630 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0043408 | Not Cancer Driver | No | 153 | 0.114 | 830 | 90 | 0.108 | 2 |
| SYNJ2BP | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | GO:0043408 | Not Cancer Driver | No | 27 | 0.186 | 12 | 4 | 0.333 | 0 |
| TAOK1 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0043408 | Not Cancer Driver | No | 116 | 0.116 | 601 | 59 | 0.098 | 0 |
| TAOK2 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0043408 | Not Cancer Driver | No | 191 | 0.155 | 666 | 102 | 0.153 | 0 |
| TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0043408 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
| TBC1D10C | TBC1D10C | Q8IV04 | Carabin | chr11 | GO:0043408 | Not Cancer Driver | No | 58 | 0.13 | 192 | 32 | 0.167 | 0 |
| TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | GO:0043408 | Not Cancer Driver | No | 43 | 0.204 | 3 | 1 | 0.333 | 5 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0043408 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR6 | TLR6 | Q9Y2C9 | Toll-like receptor 6 | chr4 | GO:0043408 | Not Cancer Driver | No | 99 | 0.124 | 1 | 0 | 0.0 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0043408 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043408 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0043408 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0043408 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
| TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | GO:0043408 | Not Cancer Driver | No | 254 | 0.187 | 781 | 156 | 0.2 | 0 |
| TNIP1_ENST00000522226 | TNIP1 | Q15025 | TNFAIP3-interacting protein 1 | chr5 | GO:0043408 | Not Cancer Driver | No | 85 | 0.134 | 625 | 83 | 0.133 | 0 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0043408 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0043408 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0043408 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| ULK4 | ULK4 | Q96C45 | Serine/threonine-protein kinase ULK4 | chr3 | GO:0043408 | Not Cancer Driver | No | 162 | 0.127 | 180 | 33 | 0.183 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0043408 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VRK2 | VRK2 | Q86Y07 | Serine/threonine-protein kinase VRK2 | chr2 | GO:0043408 | Not Cancer Driver | No | 63 | 0.124 | 126 | 15 | 0.119 | 0 |
| VRK3_ENST00000594948 | VRK3 | Q8IV63 | Inactive serine/threonine-protein kinase VRK3 | chr19 | GO:0043408 | Not Cancer Driver | No | 65 | 0.137 | 180 | 18 | 0.1 | 0 |
| WDR54 | WDR54 | Q9H977 | WD repeat-containing protein 54 | chr2 | GO:0043408 | Not Cancer Driver | No | 39 | 0.117 | 5 | 0 | 0.0 | 0 |
| WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | GO:0043408 | Census, Compendium | Yes | 223 | 0.097 | 1868 | 167 | 0.089 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0043408 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0043408 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0043408 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZMYND11 | ZMYND11 | Q15326 | Zinc finger MYND domain-containing protein 11 | chr10 | GO:0043408 | Not Cancer Driver | No | 71 | 0.118 | 184 | 26 | 0.141 | 0 |
| ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0043408 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |