Total number of protein in "GO:0043407" GO term: 58
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0043407 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0043407 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
AIDA | AIDA | Q96BJ3 | Axin interactor, dorsalization-associated protein | chr1 | GO:0043407 | Not Cancer Driver | No | 36 | 0.118 | 87 | 9 | 0.103 | 0 |
APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0043407 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0043407 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0043407 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0043407 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0043407 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0043407 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
CBLC_ENST00000647358 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | GO:0043407 | Census | Yes | 60 | 0.127 | 128 | 21 | 0.164 | 0 |
CD300A | CD300A | Q9UGN4 | CMRF35-like molecule 8 | chr17 | GO:0043407 | Not Cancer Driver | No | 53 | 0.177 | 70 | 10 | 0.143 | 0 |
CDK5RAP3_ENST00000338399 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0043407 | Not Cancer Driver | No | 50 | 0.099 | 99 | 20 | 0.202 | 0 |
DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0043407 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
DEFB114 | DEFB114 | Q30KQ6 | Beta-defensin 114 | chr6 | GO:0043407 | Not Cancer Driver | No | 31 | 0.449 | 0 | 0 | 0.0 | 0 |
DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0043407 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
DUSP1 | DUSP1 | P28562 | Dual specificity protein phosphatase 1 | chr5 | GO:0043407 | Not Cancer Driver | No | 31 | 0.084 | 7 | 0 | 0.0 | 0 |
DUSP10 | DUSP10 | Q9Y6W6 | Dual specificity protein phosphatase 10 | chr1 | GO:0043407 | Not Cancer Driver | No | 81 | 0.168 | 135 | 24 | 0.178 | 0 |
DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | GO:0043407 | Compendium | Yes | 70 | 0.105 | 273 | 34 | 0.125 | 0 |
DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0043407 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
DUSP7 | DUSP7 | Q16829 | Dual specificity protein phosphatase 7 | chr3 | GO:0043407 | Not Cancer Driver | No | 40 | 0.095 | 139 | 5 | 0.036 | 0 |
GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0043407 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0043407 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
HIPK3 | HIPK3 | Q9H422 | Homeodomain-interacting protein kinase 3 | chr11 | GO:0043407 | Not Cancer Driver | No | 128 | 0.105 | 559 | 51 | 0.091 | 0 |
HMGCR_ENST00000511206 | HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | chr5 | GO:0043407 | Not Cancer Driver | No | 84 | 0.095 | 112 | 12 | 0.107 | 0 |
HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0043407 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0043407 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0043407 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
IRAK3 | IRAK3 | Q9Y616 | Interleukin-1 receptor-associated kinase 3 | chr12 | GO:0043407 | Not Cancer Driver | No | 103 | 0.173 | 79 | 14 | 0.177 | 0 |
LAX1 | LAX1 | Q8IWV1 | Lymphocyte transmembrane adapter 1 | chr1 | GO:0043407 | Not Cancer Driver | No | 61 | 0.153 | 228 | 32 | 0.14 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0043407 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0043407 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0043407 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0043407 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0043407 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
PAQR3 | PAQR3 | Q6TCH7 | Progestin and adipoQ receptor family member 3 | chr4 | GO:0043407 | Not Cancer Driver | No | 38 | 0.122 | 0 | 0 | 0.0 | 0 |
PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0043407 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0043407 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0043407 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0043407 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0043407 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0043407 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0043407 | Census, Compendium | Yes | 73 | 0.123 | 192 | 25 | 0.13 | 0 |
PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0043407 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0043407 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
RGS2 | RGS2 | P41220 | Regulator of G-protein signaling 2 | chr1 | GO:0043407 | Not Cancer Driver | No | 30 | 0.142 | 50 | 4 | 0.08 | 0 |
SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0043407 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0043407 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0043407 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0043407 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0043407 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
SORL1 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0043407 | Not Cancer Driver | No | 374 | 0.169 | 87 | 10 | 0.115 | 0 |
SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0043407 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0043407 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
SPRY3 | SPRY3 | O43610 | Protein sprouty homolog 3 | chrX | GO:0043407 | Not Cancer Driver | No | 96 | 0.333 | 135 | 40 | 0.296 | 0 |
SPRY4_ENST00000434127 | SPRY4 | Q9C004 | Protein sprouty homolog 4 | chr5 | GO:0043407 | Not Cancer Driver | No | 34 | 0.114 | 134 | 20 | 0.149 | 7 |
STK38 | STK38 | Q15208 | Serine/threonine-protein kinase 38 | chr6 | GO:0043407 | Not Cancer Driver | No | 57 | 0.123 | 77 | 6 | 0.078 | 0 |
UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | GO:0043407 | Not Cancer Driver | No | 33 | 0.148 | 34 | 7 | 0.206 | 4 |
ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0043407 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |