Total number of protein in "GO:0043405" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0043405 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AIDA | AIDA | Q96BJ3 | Axin interactor, dorsalization-associated protein | chr1 | GO:0043405 | Not Cancer Driver | No | 36 | 0.118 | 87 | 9 | 0.103 | 0 |
| ARHGEF5 | ARHGEF5 | Q12774 | Rho guanine nucleotide exchange factor 5 | chr7 | GO:0043405 | Not Cancer Driver | No | 170 | 0.106 | 1141 | 127 | 0.111 | 0 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0043405 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0043405 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CDK12 | CDK12 | Q9NYV4 | Cyclin-dependent kinase 12 | chr17 | GO:0043405 | Census, Compendium | Yes | 225 | 0.151 | 1202 | 160 | 0.133 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0043405 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0043405 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0043405 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| DTNBP1 | DTNBP1 | Q96EV8 | Dysbindin | chr6 | GO:0043405 | Not Cancer Driver | No | 49 | 0.14 | 210 | 25 | 0.119 | 0 |
| DUSP10 | DUSP10 | Q9Y6W6 | Dual specificity protein phosphatase 10 | chr1 | GO:0043405 | Not Cancer Driver | No | 81 | 0.168 | 135 | 24 | 0.178 | 0 |
| DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | GO:0043405 | Compendium | Yes | 70 | 0.105 | 273 | 34 | 0.125 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0043405 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0043405 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0043405 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0043405 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0043405 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0043405 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| ERN2 | ERN2 | Q76MJ5 | Serine/threonine-protein kinase/endoribonuclease IRE2 | chr16 | GO:0043405 | Not Cancer Driver | No | 192 | 0.207 | 213 | 45 | 0.211 | 0 |
| FGD2 | FGD2 | Q7Z6J4 | FYVE, RhoGEF and PH domain-containing protein 2 | chr6 | GO:0043405 | Not Cancer Driver | No | 113 | 0.173 | 158 | 26 | 0.165 | 0 |
| FGF16 | FGF16 | O43320 | Fibroblast growth factor 16 | chrX | GO:0043405 | Not Cancer Driver | No | 29 | 0.14 | 28 | 6 | 0.214 | 1 |
| FZD10 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0043405 | Not Cancer Driver | No | 148 | 0.255 | 65 | 15 | 0.231 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0043405 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0043405 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| FZD8 | FZD8 | Q9H461 | Frizzled-8 | chr10 | GO:0043405 | Not Cancer Driver | No | 72 | 0.104 | 146 | 3 | 0.021 | 0 |
| GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0043405 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
| HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | GO:0043405 | Not Cancer Driver | No | 109 | 0.14 | 528 | 74 | 0.14 | 0 |
| HIPK3 | HIPK3 | Q9H422 | Homeodomain-interacting protein kinase 3 | chr11 | GO:0043405 | Not Cancer Driver | No | 128 | 0.105 | 559 | 51 | 0.091 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0043405 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | GO:0043405 | Not Cancer Driver | No | 114 | 0.124 | 404 | 58 | 0.144 | 0 |
| LIME1 | LIME1 | Q9H400 | Lck-interacting transmembrane adapter 1 | chr20 | GO:0043405 | Not Cancer Driver | No | 22 | 0.075 | 193 | 17 | 0.088 | 0 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0043405 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP3K10 | MAP3K10 | Q02779 | Mitogen-activated protein kinase kinase kinase 10 | chr19 | GO:0043405 | Not Cancer Driver | No | 112 | 0.117 | 589 | 62 | 0.105 | 0 |
| MAP3K11 | MAP3K11 | Q16584 | Mitogen-activated protein kinase kinase kinase 11 | chr11 | GO:0043405 | Not Cancer Driver | No | 97 | 0.115 | 466 | 54 | 0.116 | 0 |
| MAP3K12_ENST00000267079 | MAP3K12 | Q12852 | Mitogen-activated protein kinase kinase kinase 12 | chr12 | GO:0043405 | Not Cancer Driver | No | 120 | 0.14 | 481 | 64 | 0.133 | 0 |
| MAP3K13_ENST00000424227 | MAP3K13 | O43283 | Mitogen-activated protein kinase kinase kinase 13 | chr3 | GO:0043405 | Census | Yes | 157 | 0.163 | 593 | 91 | 0.153 | 0 |
| MAP3K4 | MAP3K4 | Q9Y6R4 | Mitogen-activated protein kinase kinase kinase 4 | chr6 | GO:0043405 | Not Cancer Driver | No | 261 | 0.162 | 520 | 86 | 0.165 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0043405 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0043405 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MAP4K2 | MAP4K2 | Q12851 | Mitogen-activated protein kinase kinase kinase kinase 2 | chr11 | GO:0043405 | Not Cancer Driver | No | 78 | 0.095 | 243 | 23 | 0.095 | 0 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0043405 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0043405 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0043405 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0043405 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PPEF2 | PPEF2 | O14830 | Serine/threonine-protein phosphatase with EF-hands 2 | chr4 | GO:0043405 | Not Cancer Driver | No | 144 | 0.191 | 130 | 29 | 0.223 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0043405 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0043405 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0043405 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0043405 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0043405 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:0043405 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0043405 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0043405 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0043405 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SNF8 | SNF8 | Q96H20 | Vacuolar-sorting protein SNF8 | chr17 | GO:0043405 | Not Cancer Driver | No | 30 | 0.116 | 10 | 2 | 0.2 | 0 |
| SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0043405 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0043405 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0043405 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
| TLR6 | TLR6 | Q9Y2C9 | Toll-like receptor 6 | chr4 | GO:0043405 | Not Cancer Driver | No | 99 | 0.124 | 1 | 0 | 0.0 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0043405 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043405 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0043405 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TNXB_ENST00000375244 | TNXB | P22105 | Tenascin-X | chr6 | GO:0043405 | Not Cancer Driver | No | 666 | 0.157 | 2794 | 498 | 0.178 | 5 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0043405 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0043405 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRIB1 | TRIB1 | Q96RU8 | Tribbles homolog 1 | chr8 | GO:0043405 | Not Cancer Driver | No | 47 | 0.126 | 91 | 5 | 0.055 | 0 |
| TRIB2 | TRIB2 | Q92519 | Tribbles homolog 2 | chr2 | GO:0043405 | Not Cancer Driver | No | 64 | 0.187 | 43 | 5 | 0.116 | 0 |
| TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0043405 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
| TSG101 | TSG101 | Q99816 | Tumor susceptibility gene 101 protein | chr11 | GO:0043405 | Not Cancer Driver | No | 46 | 0.118 | 159 | 23 | 0.145 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0043405 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0043405 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |