Total number of protein in "GO:0043280" GO term: 64
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1C | ACVR1C | Q8NER5 | Activin receptor type-1C | chr2 | GO:0043280 | Not Cancer Driver | No | 90 | 0.183 | 3 | 1 | 0.333 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0043280 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| ARL6IP5 | ARL6IP5 | O75915 | PRA1 family protein 3 | chr3 | GO:0043280 | Not Cancer Driver | No | 26 | 0.138 | 0 | 0 | 0.0 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0043280 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0043280 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0043280 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | GO:0043280 | Not Cancer Driver | No | 37 | 0.15 | 104 | 14 | 0.135 | 0 |
| BCL10 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:0043280 | Census, Compendium | Yes | 36 | 0.155 | 151 | 25 | 0.166 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0043280 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BLID | BLID | Q8IZY5 | BH3-like motif-containing cell death inducer | chr11 | GO:0043280 | Not Cancer Driver | No | 25 | 0.231 | 0 | 0 | 0.0 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0043280 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0043280 | Not Cancer Driver | No | 53 | 0.099 | 126 | 7 | 0.056 | 1 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0043280 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0043280 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0043280 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CCN1 | CCN1 | O00622 | CCN family member 1 | chr1 | GO:0043280 | Not Cancer Driver | No | 33 | 0.087 | 12 | 0 | 0.0 | 0 |
| CCN2 | CCN2 | P29279 | CCN family member 2 | chr6 | GO:0043280 | Not Cancer Driver | No | 58 | 0.166 | 0 | 0 | 0.0 | 0 |
| CLEC7A | CLEC7A | Q9BXN2 | C-type lectin domain family 7 member A | chr12 | GO:0043280 | Not Cancer Driver | No | 43 | 0.174 | 46 | 2 | 0.043 | 0 |
| CTSD | CTSD | P07339 | Cathepsin D | chr11 | GO:0043280 | Not Cancer Driver | No | 57 | 0.138 | 6 | 1 | 0.167 | 2 |
| CYCS_ENST00000409409 | CYCS | P99999 | Cytochrome c | chr7 | GO:0043280 | Not Cancer Driver | No | 12 | 0.114 | 19 | 3 | 0.158 | 1 |
| DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0043280 | Not Cancer Driver | No | 193 | 0.135 | 114 | 11 | 0.096 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0043280 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0043280 | Not Cancer Driver | No | 62 | 0.259 | 54 | 8 | 0.148 | 1 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0043280 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| FAS | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0043280 | Census, Compendium | Yes | 55 | 0.164 | 62 | 18 | 0.29 | 22 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | GO:0043280 | Not Cancer Driver | No | 25 | 0.164 | 6 | 0 | 0.0 | 0 |
| FOXL2 | FOXL2 | P58012 | Forkhead box protein L2 | chr3 | GO:0043280 | Census, Compendium | Yes | 39 | 0.104 | 257 | 20 | 0.078 | 26 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0043280 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GRAMD4_ENST00000361034 | GRAMD4 | Q6IC98 | GRAM domain-containing protein 4 | chr22 | GO:0043280 | Not Cancer Driver | No | 79 | 0.137 | 165 | 27 | 0.164 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0043280 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0043280 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0043280 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0043280 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0043280 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0043280 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0043280 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0043280 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0043280 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NDUFA13 | NDUFA13 | Q9P0J0 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | chr19 | GO:0043280 | Not Cancer Driver | No | 29 | 0.201 | 24 | 4 | 0.167 | 1 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0043280 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NLRP2 | NLRP2 | Q9NX02 | NACHT, LRR and PYD domains-containing protein 2 | chr19 | GO:0043280 | Not Cancer Driver | No | 257 | 0.242 | 60 | 15 | 0.25 | 0 |
| NLRP3_ENST00000391828 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0043280 | Not Cancer Driver | No | 339 | 0.327 | 64 | 33 | 0.516 | 37 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0043280 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0043280 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
| PDCD5 | PDCD5 | O14737 | Programmed cell death protein 5 | chr19 | GO:0043280 | Not Cancer Driver | No | 15 | 0.12 | 91 | 7 | 0.077 | 0 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0043280 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:0043280 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PPM1F | PPM1F | P49593 | Protein phosphatase 1F | chr22 | GO:0043280 | Not Cancer Driver | No | 53 | 0.117 | 242 | 24 | 0.099 | 0 |
| PRR7_ENST00000502922 | PRR7 | Q8TB68 | Proline-rich protein 7 | chr5 | GO:0043280 | Not Cancer Driver | No | 10 | 0.036 | 199 | 6 | 0.03 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0043280 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0043280 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
| RFPL1 | RFPL1 | O75677 | Ret finger protein-like 1 | chr22 | GO:0043280 | Not Cancer Driver | No | 73 | 0.23 | 28 | 5 | 0.179 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0043280 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0043280 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0043280 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0043280 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SOX7 | SOX7 | Q9BT81 | Transcription factor SOX-7 | chr8 | GO:0043280 | Not Cancer Driver | No | 92 | 0.237 | 353 | 91 | 0.258 | 0 |
| ST18 | ST18 | O60284 | Suppression of tumorigenicity 18 protein | chr8 | GO:0043280 | Not Cancer Driver | No | 330 | 0.315 | 820 | 282 | 0.344 | 0 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0043280 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0043280 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043280 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFSF10 | TNFSF10 | P50591 | Tumor necrosis factor ligand superfamily member 10 | chr3 | GO:0043280 | Not Cancer Driver | No | 43 | 0.153 | 61 | 7 | 0.115 | 0 |
| UACA | UACA | Q9BZF9 | Uveal autoantigen with coiled-coil domains and ankyrin repeats | chr15 | GO:0043280 | Not Cancer Driver | No | 177 | 0.125 | 863 | 101 | 0.117 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0043280 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |