Total number of protein in "GO:0043154" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADORA2A | ADORA2A | P29274 | Adenosine receptor A2a | chr22 | GO:0043154 | Not Cancer Driver | No | 61 | 0.148 | 93 | 11 | 0.118 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0043154 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0043154 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| ARL6IP1 | ARL6IP1 | Q15041 | ADP-ribosylation factor-like protein 6-interacting protein 1 | chr16 | GO:0043154 | Not Cancer Driver | No | 35 | 0.172 | 9 | 1 | 0.111 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0043154 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0043154 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| BCL2L12 | BCL2L12 | Q9HB09 | Bcl-2-like protein 12 | chr19 | GO:0043154 | Census, Compendium | Yes | 40 | 0.12 | 132 | 10 | 0.076 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0043154 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0043154 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
| BIRC5_ENST00000350051 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0043154 | Not Cancer Driver | No | 20 | 0.141 | 49 | 6 | 0.122 | 0 |
| BIRC7 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0043154 | Not Cancer Driver | No | 52 | 0.174 | 136 | 22 | 0.162 | 0 |
| BIRC8 | BIRC8 | Q96P09 | Baculoviral IAP repeat-containing protein 8 | chr19 | GO:0043154 | Not Cancer Driver | No | 79 | 0.335 | 39 | 10 | 0.256 | 0 |
| CAAP1 | CAAP1 | Q9H8G2 | Caspase activity and apoptosis inhibitor 1 | chr9 | GO:0043154 | Not Cancer Driver | No | 28 | 0.078 | 234 | 18 | 0.077 | 0 |
| CARD16 | CARD16 | Q5EG05 | Caspase recruitment domain-containing protein 16 | chr11 | GO:0043154 | Not Cancer Driver | No | 36 | 0.183 | 23 | 7 | 0.304 | 0 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:0043154 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | GO:0043154 | Not Cancer Driver | No | 75 | 0.101 | 542 | 60 | 0.111 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0043154 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0043154 | Not Cancer Driver | No | 22 | 0.126 | 59 | 11 | 0.186 | 4 |
| CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0043154 | Not Cancer Driver | No | 71 | 0.182 | 75 | 8 | 0.107 | 4 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0043154 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0043154 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DNAJB6 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | GO:0043154 | Not Cancer Driver | No | 33 | 0.101 | 198 | 17 | 0.086 | 3 |
| DPEP1 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0043154 | Not Cancer Driver | No | 54 | 0.131 | 41 | 6 | 0.146 | 0 |
| FABP1 | FABP1 | P07148 | Fatty acid-binding protein, liver | chr2 | GO:0043154 | Not Cancer Driver | No | 34 | 0.268 | 0 | 0 | 0.0 | 0 |
| FNIP1 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0043154 | Not Cancer Driver | No | 143 | 0.123 | 384 | 44 | 0.115 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0043154 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0043154 | Not Cancer Driver | No | 77 | 0.138 | 73 | 11 | 0.151 | 24 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0043154 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0043154 | Compendium | Yes | 233 | 0.32 | 43 | 16 | 0.372 | 0 |
| IFI6_ENST00000361157 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0043154 | Not Cancer Driver | No | 12 | 0.092 | 7 | 0 | 0.0 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0043154 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IL9 | IL9 | P15248 | Interleukin-9 | chr5 | GO:0043154 | Not Cancer Driver | No | 12 | 0.083 | 4 | 0 | 0.0 | 0 |
| LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | GO:0043154 | Not Cancer Driver | No | 67 | 0.161 | 222 | 38 | 0.171 | 0 |
| LAMTOR5_ENST00000602318 | LAMTOR5 | O43504 | Ragulator complex protein LAMTOR5 | chr1 | GO:0043154 | Not Cancer Driver | No | 10 | 0.11 | 17 | 0 | 0.0 | 0 |
| MAGEA3 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | GO:0043154 | Not Cancer Driver | No | 79 | 0.252 | 103 | 18 | 0.175 | 0 |
| MAP2K5 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0043154 | Not Cancer Driver | No | 40 | 0.089 | 85 | 10 | 0.118 | 0 |
| MICAL1_ENST00000358807 | MICAL1 | Q8TDZ2 | [F-actin]-monooxygenase MICAL1 | chr6 | GO:0043154 | Not Cancer Driver | No | 112 | 0.105 | 364 | 37 | 0.102 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0043154 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0043154 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| NAIP_ENST00000194097 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0043154 | Not Cancer Driver | No | 39 | 0.028 | 67 | 4 | 0.06 | 0 |
| NLE1 | NLE1 | Q9NVX2 | Notchless protein homolog 1 | chr17 | GO:0043154 | Not Cancer Driver | No | 60 | 0.124 | 21 | 3 | 0.143 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0043154 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0043154 | Not Cancer Driver | No | 62 | 0.104 | 252 | 24 | 0.095 | 0 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0043154 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0043154 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0043154 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | GO:0043154 | Not Cancer Driver | No | 30 | 0.103 | 157 | 13 | 0.083 | 0 |
| PLAUR | PLAUR | Q03405 | Urokinase plasminogen activator surface receptor | chr19 | GO:0043154 | Not Cancer Driver | No | 49 | 0.146 | 18 | 5 | 0.278 | 0 |
| POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | GO:0043154 | Not Cancer Driver | No | 62 | 0.092 | 93 | 4 | 0.043 | 9 |
| PRDX3 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0043154 | Not Cancer Driver | No | 23 | 0.09 | 23 | 3 | 0.13 | 0 |
| PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0043154 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0043154 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| RAF1 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0043154 | Census, Compendium | Yes | 89 | 0.137 | 169 | 38 | 0.225 | 22 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0043154 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RFFL_ENST00000394597 | RFFL | Q8WZ73 | E3 ubiquitin-protein ligase rififylin | chr17 | GO:0043154 | Not Cancer Driver | No | 50 | 0.138 | 150 | 21 | 0.14 | 0 |
| RNF34_ENST00000361234 | RNF34 | Q969K3 | E3 ubiquitin-protein ligase RNF34 | chr12 | GO:0043154 | Not Cancer Driver | No | 30 | 0.081 | 112 | 7 | 0.062 | 0 |
| RPS6KA1_ENST00000374168 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0043154 | Not Cancer Driver | No | 94 | 0.128 | 178 | 32 | 0.18 | 0 |
| RPS6KA3_ENST00000379565 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0043154 | Compendium | Yes | 106 | 0.143 | 145 | 18 | 0.124 | 13 |
| SERPINB9 | SERPINB9 | P50453 | Serpin B9 | chr6 | GO:0043154 | Not Cancer Driver | No | 64 | 0.17 | 22 | 2 | 0.091 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0043154 | Not Cancer Driver | No | 27 | 0.109 | 75 | 9 | 0.12 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0043154 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0043154 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SIAH2 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | GO:0043154 | Not Cancer Driver | No | 48 | 0.148 | 68 | 3 | 0.044 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0043154 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0043154 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0043154 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0043154 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFAIP8_ENST00000504771 | TNFAIP8 | O95379 | Tumor necrosis factor alpha-induced protein 8 | chr5 | GO:0043154 | Not Cancer Driver | No | 21 | 0.106 | 13 | 1 | 0.077 | 0 |
| TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0043154 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0043154 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| USP47 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0043154 | Not Cancer Driver | No | 137 | 0.1 | 425 | 39 | 0.092 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0043154 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0043154 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0043154 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |