Total number of protein in "GO:0043130" GO term: 100
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | GO:0043130 | Not Cancer Driver | No | 49 | 0.12 | 296 | 40 | 0.135 | 0 |
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0043130 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| ASCC2 | ASCC2 | Q9H1I8 | Activating signal cointegrator 1 complex subunit 2 | chr22 | GO:0043130 | Not Cancer Driver | No | 87 | 0.115 | 326 | 34 | 0.104 | 0 |
| AUP1 | AUP1 | Q9Y679 | Lipid droplet-regulating VLDL assembly factor AUP1 | chr2 | GO:0043130 | Not Cancer Driver | No | 41 | 0.1 | 122 | 13 | 0.107 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0043130 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BUB3 | BUB3 | O43684 | Mitotic checkpoint protein BUB3 | chr10 | GO:0043130 | Not Cancer Driver | No | 46 | 0.14 | 60 | 6 | 0.1 | 0 |
| C6orf106 | ILRUN | Q9H6K1 | Protein ILRUN | chr6 | GO:0043130 | Not Cancer Driver | No | 23 | 0.077 | 113 | 6 | 0.053 | 0 |
| CKS1B | CKS1B | P61024 | Cyclin-dependent kinases regulatory subunit 1 | chr1 | GO:0043130 | Not Cancer Driver | No | 10 | 0.127 | 10 | 0 | 0.0 | 0 |
| CKS2 | CKS2 | P33552 | Cyclin-dependent kinases regulatory subunit 2 | chr9 | GO:0043130 | Not Cancer Driver | No | 9 | 0.114 | 10 | 2 | 0.2 | 0 |
| CUEDC1_ENST00000407144 | CUEDC1 | Q9NWM3 | CUE domain-containing protein 1 | chr17 | GO:0043130 | Not Cancer Driver | No | 53 | 0.137 | 325 | 44 | 0.135 | 0 |
| CUEDC2 | CUEDC2 | Q9H467 | CUE domain-containing protein 2 | chr10 | GO:0043130 | Not Cancer Driver | No | 37 | 0.129 | 173 | 25 | 0.145 | 0 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0043130 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
| DDI2 | DDI2 | Q5TDH0 | Protein DDI1 homolog 2 | chr1 | GO:0043130 | Not Cancer Driver | No | 47 | 0.118 | 187 | 30 | 0.16 | 0 |
| DNAJB2 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | GO:0043130 | Not Cancer Driver | No | 51 | 0.157 | 239 | 40 | 0.167 | 1 |
| FAAP20_ENST00000378546 | FAAP20 | Q6NZ36 | Fanconi anemia core complex-associated protein 20 | chr1 | GO:0043130 | Not Cancer Driver | No | 23 | 0.128 | 137 | 19 | 0.139 | 0 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0043130 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FAF2 | FAF2 | Q96CS3 | FAS-associated factor 2 | chr5 | GO:0043130 | Not Cancer Driver | No | 54 | 0.121 | 171 | 16 | 0.094 | 0 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | GO:0043130 | Not Cancer Driver | No | 75 | 0.144 | 243 | 38 | 0.156 | 1 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0043130 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| GGA1 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | GO:0043130 | Not Cancer Driver | No | 75 | 0.117 | 385 | 33 | 0.086 | 0 |
| GGA2 | GGA2 | Q9UJY4 | ADP-ribosylation factor-binding protein GGA2 | chr16 | GO:0043130 | Not Cancer Driver | No | 84 | 0.137 | 240 | 37 | 0.154 | 0 |
| GGA3 | GGA3 | Q9NZ52 | ADP-ribosylation factor-binding protein GGA3 | chr17 | GO:0043130 | Not Cancer Driver | No | 73 | 0.101 | 419 | 41 | 0.098 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0043130 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | GO:0043130 | Not Cancer Driver | No | 109 | 0.14 | 528 | 74 | 0.14 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0043130 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:0043130 | Not Cancer Driver | No | 6 | 0.014 | 301 | 6 | 0.02 | 22 |
| JARID2 | JARID2 | Q92833 | Protein Jumonji | chr6 | GO:0043130 | Not Cancer Driver | No | 190 | 0.152 | 724 | 113 | 0.156 | 0 |
| MARCH7 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:0043130 | Not Cancer Driver | No | 85 | 0.121 | 550 | 68 | 0.124 | 0 |
| MARK4 | MARK4 | Q96L34 | MAP/microtubule affinity-regulating kinase 4 | chr19 | GO:0043130 | Not Cancer Driver | No | 94 | 0.125 | 403 | 46 | 0.114 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0043130 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MVB12A | MVB12A | Q96EY5 | Multivesicular body subunit 12A | chr19 | GO:0043130 | Not Cancer Driver | No | 27 | 0.099 | 67 | 4 | 0.06 | 0 |
| MVB12B | MVB12B | Q9H7P6 | Multivesicular body subunit 12B | chr9 | GO:0043130 | Not Cancer Driver | No | 34 | 0.107 | 148 | 10 | 0.068 | 0 |
| N4BP1 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0043130 | Not Cancer Driver | No | 108 | 0.121 | 432 | 58 | 0.134 | 0 |
| N4BP2 | N4BP2 | Q86UW6 | NEDD4-binding protein 2 | chr4 | GO:0043130 | Census | Yes | 185 | 0.105 | 965 | 104 | 0.108 | 0 |
| NBR1 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | GO:0043130 | Not Cancer Driver | No | 101 | 0.105 | 560 | 51 | 0.091 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0043130 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NPLOC4 | NPLOC4 | Q8TAT6 | Nuclear protein localization protein 4 homolog | chr17 | GO:0043130 | Not Cancer Driver | No | 78 | 0.128 | 47 | 8 | 0.17 | 0 |
| NSFL1C_ENST00000216879 | NSFL1C | Q9UNZ2 | NSFL1 cofactor p47 | chr20 | GO:0043130 | Not Cancer Driver | No | 56 | 0.151 | 266 | 39 | 0.147 | 0 |
| NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0043130 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | GO:0043130 | Not Cancer Driver | No | 31 | 0.114 | 33 | 2 | 0.061 | 0 |
| OTUB2 | OTUB2 | Q96DC9 | Ubiquitin thioesterase OTUB2 | chr14 | GO:0043130 | Not Cancer Driver | No | 30 | 0.128 | 0 | 0 | 0.0 | 0 |
| OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | GO:0043130 | Not Cancer Driver | No | 59 | 0.166 | 21 | 0 | 0.0 | 0 |
| PLAA | PLAA | Q9Y263 | Phospholipase A-2-activating protein | chr9 | GO:0043130 | Not Cancer Driver | No | 78 | 0.098 | 150 | 14 | 0.093 | 2 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0043130 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | GO:0043130 | Not Cancer Driver | No | 50 | 0.138 | 283 | 41 | 0.145 | 0 |
| RAD23B | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | GO:0043130 | Not Cancer Driver | No | 54 | 0.132 | 324 | 41 | 0.127 | 0 |
| RAE1_ENST00000371242 | RAE1 | P78406 | mRNA export factor RAE1 | chr20 | GO:0043130 | Not Cancer Driver | No | 64 | 0.174 | 73 | 11 | 0.151 | 0 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:0043130 | Not Cancer Driver | No | 52 | 0.102 | 140 | 14 | 0.1 | 2 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0043130 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0043130 | Not Cancer Driver | No | 25 | 0.13 | 82 | 15 | 0.183 | 0 |
| RNF19B | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0043130 | Not Cancer Driver | No | 58 | 0.079 | 344 | 24 | 0.07 | 0 |
| RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | GO:0043130 | Not Cancer Driver | No | 142 | 0.132 | 319 | 45 | 0.141 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0043130 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| RNFT1 | RNFT1 | Q5M7Z0 | E3 ubiquitin-protein ligase RNFT1 | chr17 | GO:0043130 | Not Cancer Driver | No | 37 | 0.085 | 117 | 18 | 0.154 | 0 |
| SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | GO:0043130 | Not Cancer Driver | No | 34 | 0.088 | 237 | 16 | 0.068 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0043130 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0043130 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMARCAD1_ENST00000354268 | SMARCAD1 | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 | chr4 | GO:0043130 | Not Cancer Driver | No | 129 | 0.126 | 388 | 50 | 0.129 | 0 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | GO:0043130 | Not Cancer Driver | No | 73 | 0.149 | 252 | 38 | 0.151 | 1 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0043130 | Not Cancer Driver | No | 54 | 0.123 | 267 | 32 | 0.12 | 30 |
| STAM | STAM | Q92783 | Signal transducing adapter molecule 1 | chr10 | GO:0043130 | Not Cancer Driver | No | 73 | 0.135 | 361 | 40 | 0.111 | 0 |
| STAM2 | STAM2 | O75886 | Signal transducing adapter molecule 2 | chr2 | GO:0043130 | Not Cancer Driver | No | 69 | 0.131 | 291 | 30 | 0.103 | 0 |
| TAB2_ENST00000637181 | TAB2 | Q9NYJ8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | chr6 | GO:0043130 | Not Cancer Driver | No | 87 | 0.126 | 573 | 73 | 0.127 | 2 |
| TAB3 | TAB3 | Q8N5C8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 | chrX | GO:0043130 | Not Cancer Driver | No | 130 | 0.183 | 654 | 116 | 0.177 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0043130 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TOLLIP | TOLLIP | Q9H0E2 | Toll-interacting protein | chr11 | GO:0043130 | Not Cancer Driver | No | 38 | 0.139 | 81 | 12 | 0.148 | 0 |
| TOM1L1 | TOM1L1 | O75674 | TOM1-like protein 1 | chr17 | GO:0043130 | Not Cancer Driver | No | 51 | 0.107 | 268 | 29 | 0.108 | 0 |
| TOM1L2 | TOM1L2 | Q6ZVM7 | TOM1-like protein 2 | chr17 | GO:0043130 | Not Cancer Driver | No | 57 | 0.112 | 335 | 37 | 0.11 | 0 |
| TOM1_ENST00000449058 | TOM1 | O60784 | Target of Myb protein 1 | chr22 | GO:0043130 | Not Cancer Driver | No | 70 | 0.142 | 324 | 41 | 0.127 | 0 |
| TOP2A | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0043130 | Compendium | Yes | 150 | 0.098 | 508 | 59 | 0.116 | 0 |
| TP53INP2 | TP53INP2 | Q8IXH6 | Tumor protein p53-inducible nuclear protein 2 | chr20 | GO:0043130 | Not Cancer Driver | No | 18 | 0.082 | 197 | 16 | 0.081 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0043130 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TSG101 | TSG101 | Q99816 | Tumor susceptibility gene 101 protein | chr11 | GO:0043130 | Not Cancer Driver | No | 46 | 0.118 | 159 | 23 | 0.145 | 0 |
| UBAP1L_ENST00000502113 | UBAP1L | F5GYI3 | Ubiquitin-associated protein 1-like | chr15 | GO:0043130 | Not Cancer Driver | No | 12 | 0.031 | 248 | 4 | 0.016 | 0 |
| UBAP1_ENST00000297661 | UBAP1 | Q9NZ09 | Ubiquitin-associated protein 1 | chr9 | GO:0043130 | Not Cancer Driver | No | 58 | 0.116 | 267 | 31 | 0.116 | 0 |
| UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | GO:0043130 | Compendium | Yes | 35 | 0.23 | 67 | 13 | 0.194 | 2 |
| UBE2L6 | UBE2L6 | O14933 | Ubiquitin/ISG15-conjugating enzyme E2 L6 | chr11 | GO:0043130 | Not Cancer Driver | No | 19 | 0.124 | 7 | 1 | 0.143 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | GO:0043130 | Not Cancer Driver | No | 25 | 0.164 | 24 | 3 | 0.125 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0043130 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| UBXN10 | UBXN10 | Q96LJ8 | UBX domain-containing protein 10 | chr1 | GO:0043130 | Not Cancer Driver | No | 51 | 0.182 | 254 | 48 | 0.189 | 0 |
| UBXN11_ENST00000374221 | UBXN11 | Q5T124 | UBX domain-containing protein 11 | chr1 | GO:0043130 | Not Cancer Driver | No | 74 | 0.142 | 335 | 54 | 0.161 | 0 |
| UBXN1_ENST00000301935 | UBXN1 | Q04323 | UBX domain-containing protein 1 | chr11 | GO:0043130 | Not Cancer Driver | No | 35 | 0.118 | 271 | 33 | 0.122 | 0 |
| UBXN2A | UBXN2A | P68543 | UBX domain-containing protein 2A | chr2 | GO:0043130 | Not Cancer Driver | No | 37 | 0.143 | 58 | 11 | 0.19 | 0 |
| UBXN2B | UBXN2B | Q14CS0 | UBX domain-containing protein 2B | chr8 | GO:0043130 | Not Cancer Driver | No | 51 | 0.154 | 162 | 16 | 0.099 | 0 |
| UBXN7 | UBXN7 | O94888 | UBX domain-containing protein 7 | chr3 | GO:0043130 | Not Cancer Driver | No | 65 | 0.133 | 327 | 39 | 0.119 | 0 |
| UBXN8 | UBXN8 | O00124 | UBX domain-containing protein 8 | chr8 | GO:0043130 | Not Cancer Driver | No | 25 | 0.093 | 116 | 14 | 0.121 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | GO:0043130 | Not Cancer Driver | No | 33 | 0.148 | 34 | 7 | 0.206 | 4 |
| UCHL3 | UCHL3 | P15374 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | chr13 | GO:0043130 | Not Cancer Driver | No | 26 | 0.113 | 61 | 3 | 0.049 | 0 |
| UEVLD | UEVLD | Q8IX04 | Ubiquitin-conjugating enzyme E2 variant 3 | chr11 | GO:0043130 | Not Cancer Driver | No | 45 | 0.096 | 14 | 2 | 0.143 | 0 |
| USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0043130 | Not Cancer Driver | No | 121 | 0.14 | 224 | 42 | 0.188 | 0 |
| USP16 | USP16 | Q9Y5T5 | Ubiquitin carboxyl-terminal hydrolase 16 | chr21 | GO:0043130 | Not Cancer Driver | No | 98 | 0.119 | 394 | 42 | 0.107 | 0 |
| USP25_ENST00000285679 | USP25 | Q9UHP3 | Ubiquitin carboxyl-terminal hydrolase 25 | chr21 | GO:0043130 | Not Cancer Driver | No | 135 | 0.128 | 354 | 55 | 0.155 | 0 |
| USP33_ENST00000357428 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | GO:0043130 | Not Cancer Driver | No | 138 | 0.146 | 256 | 48 | 0.188 | 0 |
| USP5 | USP5 | P45974 | Ubiquitin carboxyl-terminal hydrolase 5 | chr12 | GO:0043130 | Not Cancer Driver | No | 117 | 0.136 | 262 | 38 | 0.145 | 0 |
| USPL1 | USPL1 | Q5W0Q7 | SUMO-specific isopeptidase USPL1 | chr13 | GO:0043130 | Not Cancer Driver | No | 107 | 0.098 | 578 | 55 | 0.095 | 0 |
| VPS28_ENST00000292510 | VPS28 | Q9UK41 | Vacuolar protein sorting-associated protein 28 homolog | chr8 | GO:0043130 | Not Cancer Driver | No | 28 | 0.127 | 31 | 5 | 0.161 | 0 |
| VPS36 | VPS36 | Q86VN1 | Vacuolar protein-sorting-associated protein 36 | chr13 | GO:0043130 | Not Cancer Driver | No | 35 | 0.091 | 94 | 14 | 0.149 | 0 |
| WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0043130 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
| WDR92 | DNAAF10 | Q96MX6 | Dynein axonemal assembly factor 10 | chr2 | GO:0043130 | Not Cancer Driver | No | 36 | 0.101 | 42 | 6 | 0.143 | 0 |
| ZFAND2B_ENST00000409336 | ZFAND2B | Q8WV99 | AN1-type zinc finger protein 2B | chr2 | GO:0043130 | Not Cancer Driver | No | 24 | 0.093 | 147 | 15 | 0.102 | 0 |