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Total number of protein in "GO:0043087" GO term:  206

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABR ABR Q12979 Active breakpoint cluster region-related protein chr17 GO:0043087 Not Cancer Driver No 122 0.142 184 36 0.196 0
ADAP1_ENST00000265846 ADAP1 O75689 Arf-GAP with dual PH domain-containing protein 1 chr7 GO:0043087 Not Cancer Driver No 33 0.088 30 3 0.1 0
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0043087 Not Cancer Driver No 54 0.151 30 3 0.1 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:0043087 Compendium Yes 45 0.084 307 13 0.042 0
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0043087 Census Yes 77 0.16 84 9 0.107 2
AMOT AMOT Q4VCS5 Angiomotin chrX GO:0043087 Not Cancer Driver No 161 0.149 909 128 0.141 0
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0043087 Not Cancer Driver No 117 0.051 1725 78 0.045 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0043087 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARHGAP12 ARHGAP12 Q8IWW6 Rho GTPase-activating protein 12 chr10 GO:0043087 Not Cancer Driver No 97 0.115 497 56 0.113 0
ARHGAP15 ARHGAP15 Q53QZ3 Rho GTPase-activating protein 15 chr2 GO:0043087 Not Cancer Driver No 110 0.232 137 44 0.321 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 GO:0043087 Not Cancer Driver No 138 0.198 449 90 0.2 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0043087 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP25 ARHGAP25 P42331 Rho GTPase-activating protein 25 chr2 GO:0043087 Not Cancer Driver No 120 0.186 339 62 0.183 0
ARHGAP27 ARHGAP27 Q6ZUM4 Rho GTPase-activating protein 27 chr17 GO:0043087 Not Cancer Driver No 91 0.102 516 57 0.11 0
ARHGAP29 ARHGAP29 Q52LW3 Rho GTPase-activating protein 29 chr1 GO:0043087 Not Cancer Driver No 182 0.144 579 94 0.162 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0043087 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:0043087 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0043087 Not Cancer Driver No 110 0.097 679 68 0.1 0
ARHGAP9_ENST00000393791 ARHGAP9 Q9BRR9 Rho GTPase-activating protein 9 chr12 GO:0043087 Not Cancer Driver No 123 0.164 408 51 0.125 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0043087 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0043087 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0043087 Not Cancer Driver No 68 0.096 297 13 0.044 0
ARHGEF19 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 GO:0043087 Not Cancer Driver No 82 0.102 365 36 0.099 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0043087 Not Cancer Driver No 164 0.188 475 86 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0043087 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0043087 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0043087 Not Cancer Driver No 46 0.112 122 22 0.18 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0043087 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0043087 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0043087 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0043087 Census, Compendium Yes 146 0.115 603 69 0.114 0
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0043087 Not Cancer Driver No 59 0.164 65 15 0.231 1
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0043087 Census Yes 160 0.163 562 104 0.185 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0043087 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0043087 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCPG1_ENST00000310958 CCPG1 Q9ULG6 Cell cycle progression protein 1 chr15 GO:0043087 Not Cancer Driver No 95 0.125 509 64 0.126 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0043087 Census, Compendium Yes 50 0.132 0 0 0.0 0
CHN1 CHN1 P15882 N-chimaerin chr2 GO:0043087 Not Cancer Driver No 69 0.15 44 9 0.205 7
CHN2 CHN2 P52757 Beta-chimaerin chr7 GO:0043087 Not Cancer Driver No 74 0.158 48 10 0.208 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0043087 Not Cancer Driver No 61 0.129 84 13 0.155 0
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:0043087 Not Cancer Driver No 66 0.112 269 17 0.063 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0043087 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0043087 Not Cancer Driver No 38 0.125 160 25 0.156 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0043087 Not Cancer Driver No 11 0.101 0 0 0.0 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043087 Not Cancer Driver No 131 0.11 681 68 0.1 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0043087 Not Cancer Driver No 262 0.122 454 53 0.117 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0043087 Not Cancer Driver No 104 0.114 284 33 0.116 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0043087 Not Cancer Driver No 34 0.149 25 6 0.24 0
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0043087 Not Cancer Driver No 35 0.111 59 6 0.102 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0043087 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0043087 Compendium Yes 171 0.175 187 39 0.209 3
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0043087 Census, Compendium Yes 346 0.352 74 28 0.378 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0043087 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0043087 Not Cancer Driver No 341 0.329 83 39 0.47 0
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0043087 Not Cancer Driver No 155 0.155 137 16 0.117 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0043087 Not Cancer Driver No 70 0.088 381 27 0.071 0
EVI5_ENST00000370331 EVI5 O60447 Ecotropic viral integration site 5 protein homolog chr1 GO:0043087 Not Cancer Driver No 115 0.142 416 61 0.147 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0043087 Not Cancer Driver No 47 0.157 72 15 0.208 0
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX GO:0043087 Not Cancer Driver No 139 0.145 520 74 0.142 5
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0043087 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGD3 FGD3 Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 chr9 GO:0043087 Not Cancer Driver No 117 0.161 404 72 0.178 0
FGD4_ENST00000427716 FGD4 Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 chr12 GO:0043087 Not Cancer Driver No 78 0.102 290 28 0.097 2
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0043087 Compendium Yes 275 0.188 915 180 0.197 0
FGD6 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 GO:0043087 Not Cancer Driver No 198 0.138 804 117 0.146 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0043087 Not Cancer Driver No 46 0.1 42 3 0.071 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0043087 Not Cancer Driver No 25 0.059 279 18 0.065 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0043087 Not Cancer Driver No 148 0.255 65 15 0.231 0
GAPVD1_ENST00000495955 GAPVD1 Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 chr9 GO:0043087 Not Cancer Driver No 188 0.127 705 93 0.132 0
GARNL3 GARNL3 Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 chr9 GO:0043087 Not Cancer Driver No 115 0.114 285 34 0.119 0
GMIP GMIP Q9P107 GEM-interacting protein chr19 GO:0043087 Not Cancer Driver No 124 0.128 597 67 0.112 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:0043087 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0043087 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 GO:0043087 Not Cancer Driver No 68 0.101 344 35 0.102 0
GRTP1_ENST00000375431 GRTP1 Q5TC63 Growth hormone-regulated TBC protein 1 chr13 GO:0043087 Not Cancer Driver No 58 0.173 39 3 0.077 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0043087 Census, Compendium Yes 107 0.566 16 4 0.25 18
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0043087 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 GO:0043087 Not Cancer Driver No 237 0.15 255 50 0.196 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0043087 Not Cancer Driver No 233 0.143 257 36 0.14 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0043087 Not Cancer Driver No 26 0.13 58 11 0.19 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0043087 Not Cancer Driver No 38 0.176 0 0 0.0 0
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 GO:0043087 Not Cancer Driver No 95 0.13 380 41 0.108 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0043087 Not Cancer Driver No 519 0.205 90 17 0.189 23
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0043087 Census, Compendium Yes 226 0.163 62 15 0.242 19
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0043087 Not Cancer Driver No 56 0.098 6 1 0.167 22
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 GO:0043087 Not Cancer Driver No 37 0.113 45 3 0.067 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0043087 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0043087 Not Cancer Driver No 62 0.083 582 49 0.084 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0043087 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0043087 Not Cancer Driver No 106 0.127 516 72 0.14 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0043087 Census, Compendium Yes 375 0.132 406 47 0.116 85
NGEF NGEF Q8N5V2 Ephexin-1 chr2 GO:0043087 Not Cancer Driver No 125 0.176 296 34 0.115 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0043087 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0043087 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0043087 Census, Compendium Yes 249 0.297 57 21 0.368 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0043087 Not Cancer Driver No 151 0.168 126 24 0.19 41
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0043087 Not Cancer Driver No 42 0.102 82 11 0.134 7
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 GO:0043087 Not Cancer Driver No 100 0.137 605 86 0.142 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0043087 Not Cancer Driver No 74 0.132 216 29 0.134 0
PLXNA1 PLXNA1 Q9UIW2 Plexin-A1 chr3 GO:0043087 Not Cancer Driver No 281 0.148 228 28 0.123 0
PLXNA2 PLXNA2 O75051 Plexin-A2 chr1 GO:0043087 Not Cancer Driver No 312 0.165 142 25 0.176 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0043087 Not Cancer Driver No 243 0.13 199 34 0.171 0
PLXNA4 PLXNA4 Q9HCM2 Plexin-A4 chr7 GO:0043087 Not Cancer Driver No 591 0.312 198 63 0.318 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0043087 Not Cancer Driver No 228 0.107 684 67 0.098 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0043087 Not Cancer Driver No 273 0.149 304 35 0.115 0
PLXNB3_ENST00000361971 PLXNB3 Q9ULL4 Plexin-B3 chrX GO:0043087 Not Cancer Driver No 217 0.114 358 37 0.103 0
PLXNC1 PLXNC1 O60486 Plexin-C1 chr12 GO:0043087 Not Cancer Driver No 205 0.131 135 18 0.133 0
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0043087 Not Cancer Driver No 246 0.128 321 35 0.109 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0043087 Not Cancer Driver No 36 0.098 94 13 0.138 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 GO:0043087 Not Cancer Driver No 167 0.249 93 22 0.237 1
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0043087 Not Cancer Driver No 111 0.133 34 4 0.118 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0043087 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0043087 Not Cancer Driver No 134 0.127 425 55 0.129 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0043087 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0043087 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0043087 Not Cancer Driver No 168 0.121 143 17 0.119 2
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 GO:0043087 Not Cancer Driver No 114 0.107 407 40 0.098 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 GO:0043087 Not Cancer Driver No 116 0.142 235 33 0.14 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0043087 Not Cancer Driver No 65 0.099 381 46 0.121 0
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 GO:0043087 Not Cancer Driver No 227 0.111 649 73 0.112 1
RALGAPA2 RALGAPA2 Q2PPJ7 Ral GTPase-activating protein subunit alpha-2 chr20 GO:0043087 Not Cancer Driver No 243 0.13 415 66 0.159 0
RALGAPB_ENST00000397040 RALGAPB Q86X10 Ral GTPase-activating protein subunit beta chr20 GO:0043087 Not Cancer Driver No 202 0.135 376 54 0.144 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0043087 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAP1GAP2 RAP1GAP2 Q684P5 Rap1 GTPase-activating protein 2 chr17 GO:0043087 Not Cancer Driver No 93 0.127 413 57 0.138 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0043087 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF6_ENST00000509018 RAPGEF6 Q8TEU7 Rap guanine nucleotide exchange factor 6 chr5 GO:0043087 Not Cancer Driver No 192 0.12 789 92 0.117 0
RASA2 RASA2 Q15283 Ras GTPase-activating protein 2 chr3 GO:0043087 Compendium Yes 104 0.122 142 19 0.134 0
RASA3 RASA3 Q14644 Ras GTPase-activating protein 3 chr13 GO:0043087 Not Cancer Driver No 118 0.141 101 19 0.188 0
RASA4 RASA4 O43374 Ras GTPase-activating protein 4 chr7 GO:0043087 Not Cancer Driver No 14 0.017 164 3 0.018 0
RASA4B_ENST00000465829 RASA4B C9J798 Ras GTPase-activating protein 4B chr7 GO:0043087 Not Cancer Driver No 13 0.016 157 1 0.006 0
RASAL1_ENST00000261729 RASAL1 O95294 RasGAP-activating-like protein 1 chr12 GO:0043087 Not Cancer Driver No 132 0.164 106 25 0.236 0
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 GO:0043087 Not Cancer Driver No 164 0.144 606 86 0.142 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0043087 Not Cancer Driver No 114 0.113 536 68 0.127 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0043087 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0043087 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASGRP3_ENST00000402538 RASGRP3 Q8IV61 Ras guanyl-releasing protein 3 chr2 GO:0043087 Not Cancer Driver No 119 0.172 145 20 0.138 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0043087 Not Cancer Driver No 73 0.076 505 48 0.095 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0043087 Not Cancer Driver No 63 0.121 194 27 0.139 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0043087 Not Cancer Driver No 71 0.122 297 37 0.125 1
RGN RGN Q15493 Regucalcin chrX GO:0043087 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0043087 Not Cancer Driver No 26 0.136 22 5 0.227 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 GO:0043087 Not Cancer Driver No 212 0.124 366 50 0.137 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0043087 Not Cancer Driver No 131 0.123 421 76 0.181 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 GO:0043087 Not Cancer Driver No 74 0.098 513 48 0.094 0
RUNDC1 RUNDC1 Q96C34 RUN domain-containing protein 1 chr17 GO:0043087 Not Cancer Driver No 65 0.106 238 21 0.088 0
SBF1_ENST00000348911 SBF1 O95248 Myotubularin-related protein 5 chr22 GO:0043087 Not Cancer Driver No 210 0.112 632 63 0.1 2
SBF2 SBF2 Q86WG5 Myotubularin-related protein 13 chr11 GO:0043087 Not Cancer Driver No 221 0.12 367 55 0.15 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0043087 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SGSM1 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0043087 Not Cancer Driver No 206 0.179 418 68 0.163 0
SGSM2_ENST00000426855 SGSM2 O43147 Small G protein signaling modulator 2 chr17 GO:0043087 Not Cancer Driver No 83 0.083 316 21 0.066 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0043087 Not Cancer Driver No 83 0.111 77 9 0.117 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0043087 Not Cancer Driver No 143 0.148 241 43 0.178 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0043087 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SIPA1L2 SIPA1L2 Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 chr1 GO:0043087 Not Cancer Driver No 311 0.181 895 172 0.192 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 GO:0043087 Not Cancer Driver No 273 0.153 1257 190 0.151 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0043087 Not Cancer Driver No 67 0.064 666 43 0.065 0
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0043087 Not Cancer Driver No 83 0.129 27 3 0.111 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043087 Not Cancer Driver No 16 0.104 93 9 0.097 79
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0043087 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0043087 Not Cancer Driver No 46 0.146 169 29 0.172 1
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0043087 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN3 STMN3 Q9NZ72 Stathmin-3 chr20 GO:0043087 Not Cancer Driver No 26 0.144 152 25 0.164 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0043087 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYDE2 SYDE2 Q5VT97 Rho GTPase-activating protein SYDE2 chr1 GO:0043087 Not Cancer Driver No 136 0.114 693 69 0.1 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0043087 Not Cancer Driver No 153 0.114 830 90 0.108 2
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 GO:0043087 Not Cancer Driver No 16 0.129 51 8 0.157 0
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 GO:0043087 Not Cancer Driver No 138 0.118 455 58 0.127 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0043087 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 GO:0043087 Not Cancer Driver No 54 0.067 498 27 0.054 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0043087 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBC1D12 TBC1D12 O60347 TBC1 domain family member 12 chr10 GO:0043087 Not Cancer Driver No 62 0.08 458 20 0.044 0
TBC1D13 TBC1D13 Q9NVG8 TBC1 domain family member 13 chr9 GO:0043087 Not Cancer Driver No 49 0.122 57 10 0.175 0
TBC1D14 TBC1D14 Q9P2M4 TBC1 domain family member 14 chr4 GO:0043087 Not Cancer Driver No 80 0.115 311 36 0.116 0
TBC1D15 TBC1D15 Q8TC07 TBC1 domain family member 15 chr12 GO:0043087 Not Cancer Driver No 90 0.13 135 23 0.17 0
TBC1D16 TBC1D16 Q8TBP0 TBC1 domain family member 16 chr17 GO:0043087 Not Cancer Driver No 84 0.11 307 37 0.121 0
TBC1D17 TBC1D17 Q9HA65 TBC1 domain family member 17 chr19 GO:0043087 Not Cancer Driver No 76 0.117 191 25 0.131 0
TBC1D2 TBC1D2 Q9BYX2 TBC1 domain family member 2A chr9 GO:0043087 Not Cancer Driver No 106 0.114 338 39 0.115 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0043087 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBC1D22A TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 GO:0043087 Not Cancer Driver No 84 0.162 219 23 0.105 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 GO:0043087 Not Cancer Driver No 55 0.109 205 27 0.132 0
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX GO:0043087 Not Cancer Driver No 114 0.166 256 37 0.145 0
TBC1D26 TBC1D26 Q86UD7 TBC1 domain family member 26 chr17 GO:0043087 Not Cancer Driver No 34 0.136 66 7 0.106 0
TBC1D28 TBC1D28 Q2M2D7 TBC1 domain family member 28 chr17 GO:0043087 Not Cancer Driver No 36 0.171 61 12 0.197 0
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 GO:0043087 Not Cancer Driver No 118 0.123 419 43 0.103 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0043087 Not Cancer Driver No 173 0.133 590 90 0.153 0
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0043087 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0043087 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBC1D8B TBC1D8B Q0IIM8 TBC1 domain family member 8B chrX GO:0043087 Not Cancer Driver No 197 0.176 134 21 0.157 2
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 GO:0043087 Not Cancer Driver No 164 0.144 224 28 0.125 0
TBC1D9 TBC1D9 Q6ZT07 TBC1 domain family member 9 chr4 GO:0043087 Not Cancer Driver No 196 0.155 295 57 0.193 0
TBC1D9B TBC1D9B Q66K14 TBC1 domain family member 9B chr5 GO:0043087 Not Cancer Driver No 142 0.114 346 34 0.098 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0043087 Not Cancer Driver No 115 0.129 88 9 0.102 2
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0043087 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIAM2 TIAM2 Q8IVF5 Rho guanine nucleotide exchange factor TIAM2 chr6 GO:0043087 Not Cancer Driver No 309 0.182 779 166 0.213 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0043087 Not Cancer Driver No 24 0.119 25 4 0.16 0
TRAPPC6A_ENST00000585934 TRAPPC6A O75865 Trafficking protein particle complex subunit 6A chr19 GO:0043087 Not Cancer Driver No 28 0.176 15 3 0.2 0
TRAPPC6B TRAPPC6B Q86SZ2 Trafficking protein particle complex subunit 6B chr14 GO:0043087 Not Cancer Driver No 13 0.082 0 0 0.0 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0043087 Census, Compendium Yes 135 0.116 732 78 0.107 11
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0043087 Not Cancer Driver No 74 0.137 98 12 0.122 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0043087 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP6 USP6 P35125 Ubiquitin carboxyl-terminal hydrolase 6 chr17 GO:0043087 Census, Compendium Yes 243 0.173 537 83 0.155 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 GO:0043087 Not Cancer Driver No 113 0.136 472 81 0.172 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0043087 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0043087 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0043087 Not Cancer Driver No 153 0.181 102 18 0.176 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0043087 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043087 Not Cancer Driver No 66 0.174 0 0 0.0 2