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Total number of protein in "GO:0043068" GO term:  231

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043068 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0043068 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0043068 Not Cancer Driver No 39 0.16 92 21 0.228 1
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 GO:0043068 Not Cancer Driver No 16 0.081 77 7 0.091 0
AGT AGT P01019 Angiotensinogen chr1 GO:0043068 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0043068 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0043068 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0043068 Not Cancer Driver No 49 0.152 11 1 0.091 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0043068 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0043068 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0043068 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0043068 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0043068 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0043068 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0043068 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0043068 Census, Compendium Yes 469 0.153 225 39 0.173 41
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0043068 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0043068 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0043068 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0043068 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0043068 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0043068 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0043068 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0043068 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0043068 Not Cancer Driver No 23 0.118 74 9 0.122 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0043068 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0043068 Not Cancer Driver No 84 0.167 64 12 0.188 5
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0043068 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 GO:0043068 Not Cancer Driver No 42 0.171 115 18 0.157 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0043068 Census, Compendium Yes 21 0.123 19 0 0.0 0
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0043068 Not Cancer Driver No 18 0.121 115 13 0.113 8
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0043068 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0043068 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0043068 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0043068 Not Cancer Driver No 81 0.116 46 11 0.239 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0043068 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0043068 Census Yes 32 0.116 62 5 0.081 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0043068 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0043068 Census Yes 49 0.118 71 7 0.099 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0043068 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0043068 Not Cancer Driver No 20 0.202 15 5 0.333 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0043068 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD248 CD248 Q9HCU0 Endosialin chr11 GO:0043068 Not Cancer Driver No 110 0.145 369 58 0.157 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0043068 Census Yes 29 0.1 54 9 0.167 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0043068 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0043068 Not Cancer Driver No 56 0.215 24 7 0.292 32
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0043068 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0043068 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0043068 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0043068 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0043068 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0043068 Census, Compendium Yes 166 1.064 83 88 1.06 36
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0043068 Census, Compendium Yes 335 0.617 157 130 0.828 13
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0043068 Not Cancer Driver No 43 0.174 46 2 0.043 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0043068 Not Cancer Driver No 29 0.135 52 11 0.212 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0043068 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0043068 Census, Compendium Yes 415 0.531 288 301 1.045 14
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0043068 Not Cancer Driver No 193 0.135 114 11 0.096 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0043068 Census Yes 29 0.172 160 27 0.169 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0043068 Not Cancer Driver No 331 0.217 922 237 0.257 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0043068 Not Cancer Driver No 67 0.091 212 23 0.108 7
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 GO:0043068 Not Cancer Driver No 46 0.099 253 20 0.079 0
ECSCR ECSCR Q19T08 Endothelial cell-specific chemotaxis regulator chr5 GO:0043068 Not Cancer Driver No 5 0.024 127 3 0.024 0
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0043068 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0043068 Not Cancer Driver No 37 0.24 21 5 0.238 5
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0043068 Not Cancer Driver No 11 0.037 61 1 0.016 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0043068 Census, Compendium Yes 280 0.281 71 15 0.211 0
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0043068 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0043068 Not Cancer Driver No 158 0.208 6 2 0.333 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0043068 Not Cancer Driver No 65 0.231 94 18 0.191 1
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0043068 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0043068 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0043068 Not Cancer Driver No 41 0.128 130 22 0.169 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0043068 Not Cancer Driver No 25 0.164 6 0 0.0 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0043068 Census, Compendium Yes 59 0.102 157 19 0.121 5
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0043068 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0043068 Census, Compendium Yes 70 0.104 595 68 0.114 0
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0043068 Not Cancer Driver No 57 0.096 476 51 0.107 10
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0043068 Not Cancer Driver No 65 0.173 13 5 0.385 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0043068 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0043068 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRN GRN P28799 Progranulin chr17 GO:0043068 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0043068 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSN GSN P06396 Gelsolin chr9 GO:0043068 Not Cancer Driver No 76 0.097 316 28 0.089 2
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0043068 Not Cancer Driver No 78 0.215 43 8 0.186 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0043068 Not Cancer Driver No 178 0.147 409 59 0.144 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0043068 Not Cancer Driver No 94 0.278 85 22 0.259 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0043068 Census Yes 37 0.095 171 22 0.129 4
HTATIP2_ENST00000443524 HTATIP2 Q9BUP3 Oxidoreductase HTATIP2 chr11 GO:0043068 Not Cancer Driver No 22 0.091 14 0 0.0 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0043068 Compendium Yes 44 0.096 127 9 0.071 2
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0043068 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0043068 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0043068 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0043068 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:0043068 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:0043068 Not Cancer Driver No 72 0.13 231 29 0.126 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0043068 Not Cancer Driver No 35 0.165 58 7 0.121 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0043068 Not Cancer Driver No 148 0.347 154 63 0.409 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0043068 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0043068 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0043068 Not Cancer Driver No 191 0.166 133 12 0.09 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0043068 Census, Compendium Yes 136 0.12 59 5 0.085 5
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0043068 Not Cancer Driver No 46 0.176 16 6 0.375 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0043068 Census Yes 86 0.169 94 13 0.138 1
LEP LEP P41159 Leptin chr7 GO:0043068 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS13 LGALS13 Q9UHV8 Galactoside-binding soluble lectin 13 chr19 GO:0043068 Not Cancer Driver No 42 0.302 0 0 0.0 0
LGALS14_ENST00000392052 LGALS14 Q8TCE9 Placental protein 13-like chr19 GO:0043068 Not Cancer Driver No 35 0.252 0 0 0.0 0
LGALS16 LGALS16 A8MUM7 Galectin-16 chr19 GO:0043068 Not Cancer Driver No 19 0.134 0 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0043068 Not Cancer Driver No 54 0.152 65 16 0.246 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0043068 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0043068 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0043068 Census Yes 95 0.186 84 12 0.143 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0043068 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0043068 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0043068 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0043068 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0043068 Not Cancer Driver No 197 0.143 242 29 0.12 0
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 GO:0043068 Not Cancer Driver No 94 0.125 403 46 0.114 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0043068 Not Cancer Driver No 30 0.086 203 21 0.103 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0043068 Not Cancer Driver No 92 0.195 408 81 0.199 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0043068 Not Cancer Driver No 80 0.106 81 9 0.111 20
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0043068 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0043068 Not Cancer Driver No 27 0.101 168 14 0.083 4
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0043068 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 GO:0043068 Not Cancer Driver No 111 0.159 506 85 0.168 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043068 Census, Compendium Yes 80 0.182 299 46 0.154 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0043068 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0043068 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0043068 Not Cancer Driver No 89 0.234 88 19 0.216 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0043068 Census, Compendium Yes 375 0.132 406 47 0.116 85
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0043068 Not Cancer Driver No 35 0.15 171 16 0.094 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0043068 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0043068 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0043068 Not Cancer Driver No 101 0.179 18 8 0.444 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0043068 Not Cancer Driver No 21 0.077 10 1 0.1 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0043068 Census, Compendium Yes 168 0.211 57 8 0.14 25
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0043068 Not Cancer Driver No 10 0.122 82 10 0.122 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0043068 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0043068 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0043068 Not Cancer Driver No 11 0.058 30 0 0.0 5
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0043068 Not Cancer Driver No 35 0.103 327 33 0.101 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0043068 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0043068 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0043068 Not Cancer Driver No 57 0.122 187 32 0.171 0
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0043068 Not Cancer Driver No 12 0.092 35 5 0.143 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0043068 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0043068 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0043068 Not Cancer Driver No 140 0.134 60 13 0.217 1
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0043068 Not Cancer Driver No 24 0.079 155 12 0.077 1
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0043068 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0043068 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:0043068 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0043068 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:0043068 Not Cancer Driver No 30 0.108 65 10 0.154 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0043068 Not Cancer Driver No 2 0.037 23 1 0.043 0
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0043068 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0043068 Census Yes 72 0.143 44 4 0.091 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0043068 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0043068 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0043068 Not Cancer Driver No 72 0.12 17 1 0.059 0
PRDM11_ENST00000530656 PRDM11 Q9NQV5 PR domain-containing protein 11 chr11 GO:0043068 Not Cancer Driver No 93 0.182 236 40 0.169 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0043068 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0043068 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0043068 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0043068 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRNP PRNP P04156 Major prion protein chr20 GO:0043068 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0043068 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0043068 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0043068 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0043068 Not Cancer Driver No 14 0.078 19 2 0.105 1
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0043068 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0043068 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0043068 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 GO:0043068 Not Cancer Driver No 38 0.092 10 0 0.0 8
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0043068 Not Cancer Driver No 82 0.181 164 24 0.146 0
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX GO:0043068 Census, Compendium Yes 112 0.12 777 99 0.127 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0043068 Census, Compendium Yes 208 0.187 105 12 0.114 139
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0043068 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0043068 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0043068 Compendium Yes 82 0.122 277 39 0.141 4
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0043068 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0043068 Not Cancer Driver No 22 0.115 29 1 0.034 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0043068 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0043068 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0043068 Not Cancer Driver No 29 0.149 39 7 0.179 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0043068 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0043068 Not Cancer Driver No 18 0.158 76 7 0.092 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0043068 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0043068 Not Cancer Driver No 73 0.154 38 9 0.237 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0043068 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0043068 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0043068 Census Yes 81 0.234 68 22 0.324 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0043068 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0043068 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0043068 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0043068 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0043068 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0043068 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0043068 Census, Compendium Yes 198 0.359 195 17 0.087 8
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043068 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0043068 Not Cancer Driver No 32 0.144 25 5 0.2 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0043068 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:0043068 Not Cancer Driver No 71 0.153 60 10 0.167 0
STK17A STK17A Q9UEE5 Serine/threonine-protein kinase 17A chr7 GO:0043068 Not Cancer Driver No 44 0.106 115 16 0.139 0
STK17B_ENST00000409228 STK17B O94768 Serine/threonine-protein kinase 17B chr2 GO:0043068 Not Cancer Driver No 57 0.153 60 12 0.2 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0043068 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0043068 Not Cancer Driver No 70 0.144 231 30 0.13 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0043068 Not Cancer Driver No 55 0.176 18 3 0.167 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0043068 Census Yes 96 0.151 131 27 0.206 5
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0043068 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0043068 Not Cancer Driver No 114 0.248 306 75 0.245 6
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0043068 Not Cancer Driver No 63 0.152 47 8 0.17 3
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0043068 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0043068 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0043068 Not Cancer Driver No 43 0.204 3 1 0.333 5
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043068 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0043068 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0043068 Not Cancer Driver No 48 0.104 229 28 0.122 0
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 GO:0043068 Not Cancer Driver No 152 0.135 868 118 0.136 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0043068 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0043068 Census, Compendium Yes 229 0.337 398 143 0.359 28
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0043068 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0043068 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0043068 Not Cancer Driver No 30 0.164 32 6 0.188 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0043068 Not Cancer Driver No 64 0.15 102 16 0.157 14
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043068 Not Cancer Driver No 66 0.174 0 0 0.0 2
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0043068 Not Cancer Driver No 79 0.191 108 9 0.083 3
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0043068 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0043068 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0043068 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:0043068 Not Cancer Driver No 189 0.299 85 30 0.353 0