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Total number of protein in "GO:0043067" GO term:  669

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0043067 Not Cancer Driver No 97 0.1 140 14 0.1 5
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043067 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0043067 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 GO:0043067 Not Cancer Driver No 28 0.105 0 0 0.0 1
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0043067 Census, Compendium Yes 78 0.215 0 0 0.0 1
ADA ADA P00813 Adenosine deaminase chr20 GO:0043067 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0043067 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0043067 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0043067 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0043067 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0043067 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0043067 Not Cancer Driver No 32 0.088 49 4 0.082 1
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 GO:0043067 Not Cancer Driver No 16 0.081 77 7 0.091 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0043067 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGT AGT P01019 Angiotensinogen chr1 GO:0043067 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0043067 Not Cancer Driver No 88 0.144 166 22 0.133 11
AIFM2_ENST00000307864 AIFM2 Q9BRQ8 Ferroptosis suppressor protein 1 chr10 GO:0043067 Not Cancer Driver No 47 0.126 8 0 0.0 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0043067 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0043067 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1S1_ENST00000391834 AKT1S1 Q96B36 Proline-rich AKT1 substrate 1 chr19 GO:0043067 Not Cancer Driver No 23 0.09 256 23 0.09 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0043067 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0043067 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0043067 Not Cancer Driver No 73 0.11 73 12 0.164 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0043067 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 GO:0043067 Not Cancer Driver No 47 0.116 180 22 0.122 0
ANKRD13C ANKRD13C Q8N6S4 Ankyrin repeat domain-containing protein 13C chr1 GO:0043067 Not Cancer Driver No 71 0.131 193 24 0.124 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0043067 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0043067 Not Cancer Driver No 59 0.171 61 12 0.197 0
API5 API5 Q9BZZ5 Apoptosis inhibitor 5 chr11 GO:0043067 Not Cancer Driver No 65 0.124 92 10 0.109 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0043067 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0043067 Not Cancer Driver No 67 0.194 0 0 0.0 0
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0043067 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0043067 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARMC10 ARMC10 Q8N2F6 Armadillo repeat-containing protein 10 chr7 GO:0043067 Not Cancer Driver No 39 0.114 58 4 0.069 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0043067 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASAH1_ENST00000262097 ASAH1 Q13510 Acid ceramidase chr8 GO:0043067 Not Cancer Driver No 47 0.119 10 3 0.3 14
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0043067 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0043067 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0043067 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0043067 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0043067 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0043067 Compendium Yes 77 0.11 53 8 0.151 6
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0043067 Census, Compendium Yes 469 0.153 225 39 0.173 41
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0043067 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0043067 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0043067 Not Cancer Driver No 168 0.188 341 64 0.188 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0043067 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0043067 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0043067 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0043067 Not Cancer Driver No 37 0.083 63 7 0.111 0
BARHL1_ENST00000542090 BARHL1 Q9BZE3 BarH-like 1 homeobox protein chr9 GO:0043067 Not Cancer Driver No 43 0.131 240 30 0.125 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0043067 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0043067 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0043067 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0043067 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0043067 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0043067 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 GO:0043067 Census, Compendium Yes 40 0.12 132 10 0.076 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0043067 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0043067 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0043067 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0043067 Census, Compendium Yes 421 0.458 899 408 0.454 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0043067 Not Cancer Driver No 81 0.207 0 0 0.0 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0043067 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0043067 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0043067 Not Cancer Driver No 88 0.161 267 38 0.142 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0043067 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0043067 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0043067 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0043067 Not Cancer Driver No 52 0.174 136 22 0.162 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0043067 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0043067 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0043067 Census Yes 163 0.359 112 62 0.554 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0043067 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0043067 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0043067 Not Cancer Driver No 84 0.167 64 12 0.188 5
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0043067 Not Cancer Driver No 16 0.073 175 14 0.08 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0043067 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0043067 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 GO:0043067 Not Cancer Driver No 42 0.171 115 18 0.157 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0043067 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0043067 Census Yes 32 0.203 7 2 0.286 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0043067 Census, Compendium Yes 147 0.223 114 27 0.237 110
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0043067 Not Cancer Driver No 28 0.078 234 18 0.077 0
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0043067 Not Cancer Driver No 18 0.121 115 13 0.113 8
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0043067 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0043067 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0043067 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0043067 Not Cancer Driver No 81 0.116 46 11 0.239 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0043067 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0043067 Census Yes 32 0.116 62 5 0.081 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0043067 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0043067 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0043067 Census Yes 49 0.118 71 7 0.099 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 GO:0043067 Not Cancer Driver No 73 0.103 708 73 0.103 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0043067 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0043067 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0043067 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0043067 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0043067 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0043067 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0043067 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0043067 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD248 CD248 Q9HCU0 Endosialin chr11 GO:0043067 Not Cancer Driver No 110 0.145 369 58 0.157 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0043067 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0043067 Census Yes 29 0.1 54 9 0.167 0
CD3G CD3G P09693 T-cell surface glycoprotein CD3 gamma chain chr11 GO:0043067 Not Cancer Driver No 25 0.137 48 7 0.146 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0043067 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD40LG CD40LG P29965 CD40 ligand chrX GO:0043067 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD44 CD44 P16070 CD44 antigen chr11 GO:0043067 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0043067 Census Yes 31 0.105 185 20 0.108 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0043067 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0043067 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0043067 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0043067 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0043067 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0043067 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0043067 Not Cancer Driver No 17 0.102 44 3 0.068 0
CDSN CDSN Q15517 Corneodesmosin chr6 GO:0043067 Not Cancer Driver No 56 0.106 469 52 0.111 0
CEACAM5 CEACAM5 P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 GO:0043067 Not Cancer Driver No 135 0.192 256 48 0.188 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0043067 Not Cancer Driver No 63 0.183 110 19 0.173 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0043067 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 GO:0043067 Not Cancer Driver No 21 0.07 273 18 0.066 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0043067 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0043067 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0043067 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHL1_ENST00000397491 CHL1 O00533 Neural cell adhesion molecule L1-like protein chr3 GO:0043067 Not Cancer Driver No 348 0.288 415 121 0.292 0
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0043067 Not Cancer Driver No 43 0.196 32 3 0.094 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0043067 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0043067 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC5A CLEC5A Q9NY25 C-type lectin domain family 5 member A chr7 GO:0043067 Not Cancer Driver No 46 0.245 0 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0043067 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0043067 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0043067 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0043067 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:0043067 Not Cancer Driver No 50 0.134 92 8 0.087 0
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0043067 Census Yes 258 0.174 1215 207 0.17 64
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0043067 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0043067 Not Cancer Driver No 85 0.117 443 54 0.122 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0043067 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0043067 Census Yes 68 0.131 372 50 0.134 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0043067 Not Cancer Driver No 51 0.121 101 7 0.069 14
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0043067 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0043067 Not Cancer Driver No 11 0.076 34 3 0.088 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0043067 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0043067 Census, Compendium Yes 415 0.531 288 301 1.045 14
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0043067 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0043067 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0043067 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0043067 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0043067 Census, Compendium Yes 116 0.121 213 31 0.146 3
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0043067 Not Cancer Driver No 193 0.135 114 11 0.096 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:0043067 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0043067 Census Yes 29 0.172 160 27 0.169 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0043067 Census, Compendium Yes 133 0.201 301 47 0.156 18
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0043067 Not Cancer Driver No 47 0.142 113 18 0.159 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0043067 Not Cancer Driver No 56 0.13 9 0 0.0 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0043067 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0043067 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0043067 Not Cancer Driver No 25 0.098 183 21 0.115 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0043067 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 GO:0043067 Not Cancer Driver No 23 0.116 46 6 0.13 1
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0043067 Not Cancer Driver No 67 0.091 212 23 0.108 7
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0043067 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0043067 Not Cancer Driver No 321 0.153 312 60 0.192 1
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0043067 Not Cancer Driver No 61 0.175 249 48 0.193 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 GO:0043067 Not Cancer Driver No 46 0.099 253 20 0.079 0
ECSCR ECSCR Q19T08 Endothelial cell-specific chemotaxis regulator chr5 GO:0043067 Not Cancer Driver No 5 0.024 127 3 0.024 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0043067 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0043067 Not Cancer Driver No 29 0.141 46 5 0.109 0
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 GO:0043067 Not Cancer Driver No 52 0.128 201 17 0.085 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0043067 Not Cancer Driver No 33 0.138 13 0 0.0 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0043067 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0043067 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0043067 Not Cancer Driver No 37 0.24 21 5 0.238 5
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0043067 Not Cancer Driver No 50 0.126 186 13 0.07 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0043067 Not Cancer Driver No 42 0.107 357 30 0.084 0
EN2 EN2 P19622 Homeobox protein engrailed-2 chr7 GO:0043067 Not Cancer Driver No 23 0.069 317 23 0.073 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0043067 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0043067 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0043067 Not Cancer Driver No 51 0.118 21 2 0.095 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0043067 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPO EPO P01588 Erythropoietin chr7 GO:0043067 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0043067 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0043067 Not Cancer Driver No 29 0.111 34 5 0.147 0
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0043067 Not Cancer Driver No 168 0.284 341 99 0.29 15
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0043067 Not Cancer Driver No 107 0.199 204 50 0.245 0
EYA3 EYA3 Q99504 Eyes absent homolog 3 chr1 GO:0043067 Not Cancer Driver No 58 0.101 310 40 0.129 0
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 GO:0043067 Not Cancer Driver No 183 0.286 337 108 0.32 2
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0043067 Not Cancer Driver No 73 0.172 19 2 0.105 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0043067 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0043067 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0043067 Not Cancer Driver No 37 0.117 54 11 0.204 0
FAIM_ENST00000393035 FAIM Q9NVQ4 Fas apoptotic inhibitory molecule 1 chr3 GO:0043067 Not Cancer Driver No 20 0.112 1 0 0.0 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0043067 Not Cancer Driver No 158 0.208 6 2 0.333 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0043067 Not Cancer Driver No 65 0.231 94 18 0.191 1
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0043067 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0043067 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0043067 Not Cancer Driver No 41 0.128 130 22 0.169 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0043067 Not Cancer Driver No 69 0.11 33 3 0.091 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0043067 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0043067 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0043067 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0043067 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0043067 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0043067 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0043067 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0043067 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0043067 Not Cancer Driver No 81 0.179 53 8 0.151 8
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0043067 Not Cancer Driver No 25 0.164 6 0 0.0 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0043067 Census, Compendium Yes 59 0.102 157 19 0.121 5
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0043067 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0043067 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0043067 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0043067 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0043067 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0043067 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 GO:0043067 Not Cancer Driver No 22 0.055 245 4 0.016 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0043067 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0043067 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0043067 Not Cancer Driver No 55 0.093 61 0 0.0 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0043067 Not Cancer Driver No 86 0.167 28 3 0.107 58
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0043067 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0043067 Not Cancer Driver No 165 0.322 27 10 0.37 1
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0043067 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0043067 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0043067 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0043067 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0043067 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0043067 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0043067 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBE1 GBE1 Q04446 1,4-alpha-glucan-branching enzyme chr3 GO:0043067 Not Cancer Driver No 101 0.144 8 0 0.0 9
GCG GCG P01275 Pro-glucagon chr2 GO:0043067 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0043067 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0043067 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0043067 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0043067 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:0043067 Not Cancer Driver No 176 0.447 5 2 0.4 0
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0043067 Not Cancer Driver No 50 0.145 8 0 0.0 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0043067 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIMAP8 GIMAP8 Q8ND71 GTPase IMAP family member 8 chr7 GO:0043067 Not Cancer Driver No 196 0.295 137 34 0.248 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0043067 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0043067 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0043067 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0043067 Not Cancer Driver No 38 0.187 12 1 0.083 0
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0043067 Not Cancer Driver No 14 0.071 0 0 0.0 0
GRIA4_ENST00000530497 GRIA4 P48058 Glutamate receptor 4 chr11 GO:0043067 Not Cancer Driver No 227 0.252 63 25 0.397 4
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0043067 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0043067 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0043067 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:0043067 Not Cancer Driver No 39 0.105 150 15 0.1 0
GRM4 GRM4 Q14833 Metabotropic glutamate receptor 4 chr6 GO:0043067 Not Cancer Driver No 187 0.205 74 22 0.297 0
GRN GRN P28799 Progranulin chr17 GO:0043067 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0043067 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0043067 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0043067 Not Cancer Driver No 76 0.097 316 28 0.089 2
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0043067 Not Cancer Driver No 47 0.217 124 29 0.234 0
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0043067 Not Cancer Driver No 78 0.215 43 8 0.186 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0043067 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0043067 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:0043067 Not Cancer Driver No 35 0.146 203 29 0.143 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0043067 Census Yes 38 0.097 248 17 0.069 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0043067 Not Cancer Driver No 64 0.19 179 26 0.145 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0043067 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0043067 Census Yes 118 0.143 435 51 0.117 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0043067 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0043067 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0043067 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0043067 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0043067 Not Cancer Driver No 75 0.162 302 59 0.195 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0043067 Census Yes 37 0.095 171 22 0.129 4
HRAS HRAS P01112 GTPase HRas chr11 GO:0043067 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0043067 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSH2D HSH2D Q96JZ2 Hematopoietic SH2 domain-containing protein chr19 GO:0043067 Not Cancer Driver No 44 0.125 233 38 0.163 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0043067 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0043067 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0043067 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0043067 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0043067 Compendium Yes 44 0.096 127 9 0.071 2
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0043067 Not Cancer Driver No 132 0.132 373 47 0.126 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0043067 Not Cancer Driver No 61 0.115 251 28 0.112 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0043067 Not Cancer Driver No 82 0.203 41 8 0.195 0
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 GO:0043067 Not Cancer Driver No 3 0.037 0 0 0.0 2
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0043067 Not Cancer Driver No 12 0.092 7 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0043067 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0043067 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0043067 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0043067 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0043067 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0043067 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0043067 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:0043067 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0043067 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0043067 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0043067 Census Yes 24 0.157 6 1 0.167 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:0043067 Not Cancer Driver No 72 0.13 231 29 0.126 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0043067 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0043067 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0043067 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0043067 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0043067 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0043067 Census, Compendium Yes 177 0.386 88 48 0.545 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0043067 Not Cancer Driver No 12 0.083 4 0 0.0 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0043067 Not Cancer Driver No 33 0.118 169 26 0.154 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0043067 Not Cancer Driver No 148 0.347 154 63 0.409 0
INS INS P01308 Insulin chr11 GO:0043067 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0043067 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0043067 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0043067 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0043067 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0043067 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0043067 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0043067 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0043067 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0043067 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPRIP_ENST00000358187 ITPRIP Q8IWB1 Inositol 1,4,5-trisphosphate receptor-interacting protein chr10 GO:0043067 Not Cancer Driver No 62 0.113 66 10 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0043067 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0043067 Census, Compendium Yes 167 0.149 63 10 0.159 7
JUN JUN P05412 Transcription factor Jun chr1 GO:0043067 Census Yes 35 0.106 281 25 0.089 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0043067 Not Cancer Driver No 192 0.224 417 100 0.24 6
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0043067 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0043067 Not Cancer Driver No 187 0.14 617 90 0.146 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0043067 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0043067 Not Cancer Driver No 222 0.135 774 102 0.132 2
KITLG KITLG P21583 Kit ligand chr12 GO:0043067 Not Cancer Driver No 48 0.176 61 9 0.148 1
KRAS KRAS P01116 GTPase KRas chr12 GO:0043067 Census, Compendium Yes 788 4.169 7 2 0.286 27
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0043067 Not Cancer Driver No 80 0.109 113 17 0.15 2
LANCL1_ENST00000450366 LANCL1 O43813 Glutathione S-transferase LANCL1 chr2 GO:0043067 Not Cancer Driver No 45 0.113 10 0 0.0 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0043067 Not Cancer Driver No 46 0.176 16 6 0.375 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0043067 Census Yes 86 0.169 94 13 0.138 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0043067 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0043067 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS13 LGALS13 Q9UHV8 Galactoside-binding soluble lectin 13 chr19 GO:0043067 Not Cancer Driver No 42 0.302 0 0 0.0 0
LGALS14_ENST00000392052 LGALS14 Q8TCE9 Placental protein 13-like chr19 GO:0043067 Not Cancer Driver No 35 0.252 0 0 0.0 0
LGALS16 LGALS16 A8MUM7 Galectin-16 chr19 GO:0043067 Not Cancer Driver No 19 0.134 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0043067 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0043067 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0043067 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0043067 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0043067 Not Cancer Driver No 203 0.312 291 97 0.333 0
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0043067 Census Yes 68 0.102 544 49 0.09 131
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0043067 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0043067 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0043067 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0043067 Census Yes 95 0.186 84 12 0.143 0
LYPD3 LYPD3 O95274 Ly6/PLAUR domain-containing protein 3 chr19 GO:0043067 Not Cancer Driver No 52 0.15 116 15 0.129 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:0043067 Not Cancer Driver No 207 0.126 723 81 0.112 4
MAEA MAEA Q7L5Y9 E3 ubiquitin-protein transferase MAEA chr4 GO:0043067 Not Cancer Driver No 58 0.146 64 5 0.078 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0043067 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0043067 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0043067 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0043067 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0043067 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0043067 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0043067 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0043067 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0043067 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0043067 Not Cancer Driver No 92 0.113 490 50 0.102 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0043067 Not Cancer Driver No 85 0.121 550 68 0.124 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0043067 Not Cancer Driver No 30 0.086 203 21 0.103 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0043067 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0043067 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0043067 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0043067 Not Cancer Driver No 92 0.195 408 81 0.199 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0043067 Not Cancer Driver No 175 0.175 159 31 0.195 3
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0043067 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0043067 Not Cancer Driver No 80 0.106 81 9 0.111 20
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0043067 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0043067 Not Cancer Driver No 129 0.182 124 26 0.21 0
MPV17L MPV17L Q2QL34 Mpv17-like protein chr16 GO:0043067 Not Cancer Driver No 16 0.082 3 0 0.0 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0043067 Census Yes 92 0.099 37 4 0.108 70
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0043067 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0043067 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0043067 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0043067 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTRNR2L12 MTRNR2L12 P0DMP1 Humanin-like 12 chr3 GO:0043067 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L4 MTRNR2L4 P0CJ71 Humanin-like 4 chr16 GO:0043067 Not Cancer Driver No 1 0.036 0 0 0.0 0
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0043067 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L7 MTRNR2L7 P0CJ74 Humanin-like 7 chr10 GO:0043067 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L8 MTRNR2L8 P0CJ75 Humanin-like 8 chr11 GO:0043067 Not Cancer Driver No 1 0.042 0 0 0.0 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0043067 Census Yes 40 0.032 1050 19 0.018 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0043067 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 GO:0043067 Not Cancer Driver No 111 0.159 506 85 0.168 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043067 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0043067 Not Cancer Driver No 284 0.303 853 263 0.308 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0043067 Not Cancer Driver No 24 0.041 238 10 0.042 0
NAE1_ENST00000290810 NAE1 Q13564 NEDD8-activating enzyme E1 regulatory subunit chr16 GO:0043067 Not Cancer Driver No 39 0.073 69 3 0.043 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0043067 Not Cancer Driver No 39 0.028 67 4 0.06 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0043067 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0043067 Not Cancer Driver No 89 0.234 88 19 0.216 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0043067 Not Cancer Driver No 125 0.22 129 29 0.225 1
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0043067 Not Cancer Driver No 92 0.169 285 39 0.137 12
NES NES P48681 Nestin chr1 GO:0043067 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0043067 Not Cancer Driver No 84 0.236 202 52 0.257 2
NF1 NF1 P21359 Neurofibromin chr17 GO:0043067 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0043067 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0043067 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0043067 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0043067 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0043067 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0043067 Not Cancer Driver No 60 0.124 21 3 0.143 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0043067 Not Cancer Driver No 17 0.08 6 0 0.0 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 GO:0043067 Not Cancer Driver No 77 0.103 281 31 0.11 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0043067 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0043067 Not Cancer Driver No 20 0.096 179 17 0.095 2
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0043067 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0043067 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0043067 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0043067 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0043067 Not Cancer Driver No 101 0.179 18 8 0.444 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0043067 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0043067 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 GO:0043067 Not Cancer Driver No 30 0.06 110 5 0.045 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0043067 Compendium Yes 146 0.158 211 31 0.147 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0043067 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0043067 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0043067 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0043067 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0043067 Not Cancer Driver No 155 0.189 117 18 0.154 1
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0043067 Not Cancer Driver No 10 0.122 82 10 0.122 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0043067 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0043067 Not Cancer Driver No 114 0.119 131 17 0.13 60
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0043067 Not Cancer Driver No 22 0.144 9 1 0.111 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0043067 Not Cancer Driver No 126 0.144 544 76 0.14 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0043067 Not Cancer Driver No 51 0.086 14 2 0.143 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0043067 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0043067 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0043067 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 GO:0043067 Not Cancer Driver No 58 0.098 340 33 0.097 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0043067 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0043067 Not Cancer Driver No 49 0.129 28 5 0.179 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0043067 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0043067 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0043067 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0043067 Census Yes 84 0.187 291 55 0.189 4
PCDHGC3 PCDHGC3 Q9UN70 Protocadherin gamma-C3 chr5 GO:0043067 Not Cancer Driver No 113 0.121 367 34 0.093 0
PCDHGC4 PCDHGC4 Q9Y5F7 Protocadherin gamma-C4 chr5 GO:0043067 Not Cancer Driver No 136 0.145 460 59 0.128 0
PCDHGC5 PCDHGC5 Q9Y5F6 Protocadherin gamma-C5 chr5 GO:0043067 Not Cancer Driver No 135 0.143 492 72 0.146 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0043067 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0043067 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0043067 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0043067 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0043067 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0043067 Not Cancer Driver No 32 0.113 238 23 0.097 0
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0043067 Not Cancer Driver No 12 0.092 35 5 0.143 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0043067 Not Cancer Driver No 47 0.112 167 17 0.102 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0043067 Not Cancer Driver No 13 0.129 0 0 0.0 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0043067 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0043067 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0043067 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0043067 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0043067 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0043067 Not Cancer Driver No 318 0.289 121 39 0.322 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0043067 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP PIP P12273 Prolactin-inducible protein chr7 GO:0043067 Not Cancer Driver No 42 0.288 0 0 0.0 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0043067 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0043067 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0043067 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0043067 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0043067 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:0043067 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0043067 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0043067 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:0043067 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0043067 Not Cancer Driver No 92 0.134 178 21 0.118 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0043067 Not Cancer Driver No 2 0.037 23 1 0.043 0
POU3F4_ENST00000644024 POU3F4 P49335 POU domain, class 3, transcription factor 4 chrX GO:0043067 Not Cancer Driver No 115 0.319 263 80 0.304 5
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0043067 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0043067 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0043067 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0043067 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0043067 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0043067 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0043067 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0043067 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0043067 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0043067 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0043067 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0043067 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRDM11_ENST00000530656 PRDM11 Q9NQV5 PR domain-containing protein 11 chr11 GO:0043067 Not Cancer Driver No 93 0.182 236 40 0.169 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0043067 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0043067 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0043067 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0043067 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0043067 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0043067 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0043067 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0043067 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0043067 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0043067 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0043067 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0043067 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRNP PRNP P04156 Major prion protein chr20 GO:0043067 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0043067 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0043067 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTCRA_ENST00000304672 PTCRA Q6ISU1 Pre T-cell antigen receptor alpha chr6 GO:0043067 Not Cancer Driver No 36 0.128 121 12 0.099 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0043067 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0043067 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0043067 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0043067 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0043067 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0043067 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0043067 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0043067 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0043067 Not Cancer Driver No 480 0.207 978 216 0.221 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0043067 Not Cancer Driver No 14 0.078 19 2 0.105 1
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0043067 Not Cancer Driver No 23 0.128 30 9 0.3 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0043067 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0043067 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0043067 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0043067 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0043067 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0043067 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 GO:0043067 Not Cancer Driver No 38 0.092 10 0 0.0 8
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0043067 Compendium Yes 154 0.147 181 25 0.138 3
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0043067 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:0043067 Not Cancer Driver No 52 0.102 140 14 0.1 2
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX GO:0043067 Census, Compendium Yes 112 0.12 777 99 0.127 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0043067 Census, Compendium Yes 208 0.187 105 12 0.114 139
RETREG1 RETREG1 Q9H6L5 Reticulophagy regulator 1 chr5 GO:0043067 Not Cancer Driver No 48 0.097 245 21 0.086 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0043067 Not Cancer Driver No 50 0.138 150 21 0.14 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0043067 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0043067 Not Cancer Driver No 87 0.112 461 51 0.111 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0043067 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0043067 Compendium Yes 82 0.122 277 39 0.141 4
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0043067 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0043067 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0043067 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0043067 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0043067 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0043067 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0043067 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0043067 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0043067 Not Cancer Driver No 66 0.101 115 15 0.13 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0043067 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0043067 Not Cancer Driver No 18 0.158 76 7 0.092 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0043067 Not Cancer Driver No 116 0.188 531 103 0.194 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0043067 Not Cancer Driver No 19 0.062 168 4 0.024 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0043067 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0043067 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0043067 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0043067 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINB13_ENST00000344731 SERPINB13 Q9UIV8 Serpin B13 chr18 GO:0043067 Not Cancer Driver No 84 0.215 55 16 0.291 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0043067 Not Cancer Driver No 78 0.194 7 2 0.286 0
SET SET Q01105 Protein SET chr9 GO:0043067 Census, Compendium Yes 35 0.121 221 26 0.118 2
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0043067 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0043067 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0043067 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0043067 Census Yes 81 0.234 68 22 0.324 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0043067 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0043067 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIGMAR1 SIGMAR1 Q99720 Sigma non-opioid intracellular receptor 1 chr9 GO:0043067 Not Cancer Driver No 22 0.099 2 0 0.0 1
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0043067 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0043067 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0043067 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0043067 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 GO:0043067 Not Cancer Driver No 41 0.132 55 7 0.127 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0043067 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0043067 Not Cancer Driver No 99 0.127 460 58 0.126 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0043067 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0043067 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC25A31 SLC25A31 Q9H0C2 ADP/ATP translocase 4 chr4 GO:0043067 Not Cancer Driver No 68 0.216 8 0 0.0 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0043067 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0043067 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX GO:0043067 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0043067 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC35F6 SLC35F6 Q8N357 Solute carrier family 35 member F6 chr2 GO:0043067 Not Cancer Driver No 33 0.089 13 0 0.0 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0043067 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0043067 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0043067 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0043067 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0043067 Census, Compendium Yes 198 0.359 195 17 0.087 8
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0043067 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0043067 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0043067 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:0043067 Not Cancer Driver No 23 0.172 110 21 0.191 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0043067 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043067 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0043067 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0043067 Compendium Yes 86 0.169 495 82 0.166 18
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0043067 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0043067 Not Cancer Driver No 70 0.135 235 39 0.166 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0043067 Not Cancer Driver No 50 0.106 27 5 0.185 5
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0043067 Census Yes 53 0.099 130 11 0.085 1
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0043067 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:0043067 Not Cancer Driver No 71 0.153 60 10 0.167 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0043067 Not Cancer Driver No 69 0.201 259 49 0.189 0
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0043067 Not Cancer Driver No 51 0.15 6 0 0.0 0
ST6GAL1 ST6GAL1 P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 chr3 GO:0043067 Not Cancer Driver No 55 0.135 34 8 0.235 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0043067 Not Cancer Driver No 51 0.12 139 16 0.115 6
STK17A STK17A Q9UEE5 Serine/threonine-protein kinase 17A chr7 GO:0043067 Not Cancer Driver No 44 0.106 115 16 0.139 0
STK17B_ENST00000409228 STK17B O94768 Serine/threonine-protein kinase 17B chr2 GO:0043067 Not Cancer Driver No 57 0.153 60 12 0.2 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0043067 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0043067 Not Cancer Driver No 70 0.144 231 30 0.13 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0043067 Not Cancer Driver No 53 0.127 84 7 0.083 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0043067 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0043067 Not Cancer Driver No 97 0.163 111 23 0.207 18
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0043067 Not Cancer Driver No 55 0.176 18 3 0.167 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0043067 Census Yes 96 0.151 131 27 0.206 5
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0043067 Not Cancer Driver No 153 0.114 830 90 0.108 2
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0043067 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0043067 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:0043067 Not Cancer Driver No 48 0.191 189 34 0.18 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0043067 Not Cancer Driver No 35 0.088 197 12 0.061 4
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0043067 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0043067 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0043067 Not Cancer Driver No 219 0.195 126 22 0.175 10
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0043067 Census Yes 110 0.097 212 16 0.075 31
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0043067 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0043067 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFAP2D TFAP2D Q7Z6R9 Transcription factor AP-2-delta chr6 GO:0043067 Not Cancer Driver No 164 0.363 161 54 0.335 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0043067 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0043067 Not Cancer Driver No 45 0.109 96 14 0.146 1
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0043067 Not Cancer Driver No 188 0.161 320 58 0.181 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0043067 Not Cancer Driver No 69 0.141 207 30 0.145 2
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0043067 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0043067 Not Cancer Driver No 43 0.204 3 1 0.333 5
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 GO:0043067 Not Cancer Driver No 111 0.144 381 53 0.139 0
TMBIM1_ENST00000396809 TMBIM1 Q969X1 Protein lifeguard 3 chr2 GO:0043067 Not Cancer Driver No 30 0.096 83 8 0.096 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0043067 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMC8 TMC8 Q8IU68 Transmembrane channel-like protein 8 chr17 GO:0043067 Not Cancer Driver No 61 0.084 107 10 0.093 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0043067 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0043067 Not Cancer Driver No 49 0.102 22 8 0.364 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043067 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0043067 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0043067 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0043067 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 GO:0043067 Not Cancer Driver No 43 0.1 316 36 0.114 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 GO:0043067 Not Cancer Driver No 85 0.148 485 72 0.148 0
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 GO:0043067 Not Cancer Driver No 152 0.135 868 118 0.136 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0043067 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0043067 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:0043067 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0043067 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0043067 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0043067 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0043067 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM2_ENST00000437508 TRIM2 Q9C040 Tripartite motif-containing protein 2 chr4 GO:0043067 Not Cancer Driver No 86 0.116 238 38 0.16 1
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0043067 Not Cancer Driver No 82 0.126 87 10 0.115 3
TSC22D3_ENST00000372397 TSC22D3 Q99576 TSC22 domain family protein 3 chrX GO:0043067 Not Cancer Driver No 18 0.134 51 9 0.176 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:0043067 Not Cancer Driver No 21 0.122 44 6 0.136 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0043067 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0043067 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0043067 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0043067 Not Cancer Driver No 30 0.164 32 6 0.188 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0043067 Not Cancer Driver No 64 0.109 543 58 0.107 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0043067 Not Cancer Driver No 155 0.164 117 20 0.171 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0043067 Not Cancer Driver No 137 0.1 425 39 0.092 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0043067 Not Cancer Driver No 64 0.15 102 16 0.157 14
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0043067 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSTM2L VSTM2L Q96N03 V-set and transmembrane domain-containing protein 2-like protein chr20 GO:0043067 Not Cancer Driver No 28 0.137 134 19 0.142 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0043067 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043067 Not Cancer Driver No 66 0.174 0 0 0.0 2
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0043067 Not Cancer Driver No 79 0.191 108 9 0.083 3
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0043067 Not Cancer Driver No 19 0.073 169 9 0.053 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0043067 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0043067 Not Cancer Driver No 36 0.129 9 1 0.111 2
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0043067 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0043067 Not Cancer Driver No 49 0.132 359 47 0.131 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0043067 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0043067 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0043067 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZC3HC1 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 GO:0043067 Not Cancer Driver No 70 0.139 250 34 0.136 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0043067 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0043067 Compendium Yes 57 0.169 212 30 0.142 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0043067 Not Cancer Driver No 126 0.191 54 12 0.222 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0043067 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0043067 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:0043067 Not Cancer Driver No 189 0.299 85 30 0.353 0