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Total number of protein in "GO:0043066" GO term:  786

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0043066 Not Cancer Driver No 97 0.1 140 14 0.1 5
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043066 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0043066 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0043066 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 GO:0043066 Not Cancer Driver No 114 0.302 48 19 0.396 11
ADA ADA P00813 Adenosine deaminase chr20 GO:0043066 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0043066 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAMTS20 ADAMTS20 P59510 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 GO:0043066 Not Cancer Driver No 495 0.259 120 33 0.275 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0043066 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0043066 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0043066 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0043066 Not Cancer Driver No 61 0.148 93 11 0.118 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0043066 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:0043066 Not Cancer Driver No 100 0.116 183 24 0.131 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0043066 Not Cancer Driver No 120 0.1 500 56 0.112 6
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0043066 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIPL1 AIPL1 Q9NZN9 Aryl-hydrocarbon-interacting protein-like 1 chr17 GO:0043066 Not Cancer Driver No 52 0.135 113 14 0.124 2
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0043066 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0043066 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0043066 Census Yes 77 0.16 84 9 0.107 2
ALB ALB P02768 Albumin chr4 GO:0043066 Compendium Yes 162 0.266 6 0 0.0 3
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0043066 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0043066 Not Cancer Driver No 73 0.11 73 12 0.164 0
AMIGO2_ENST00000429635 AMIGO2 Q86SJ2 Amphoterin-induced protein 2 chr12 GO:0043066 Not Cancer Driver No 81 0.155 44 6 0.136 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0043066 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0043066 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 GO:0043066 Not Cancer Driver No 47 0.116 180 22 0.122 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0043066 Not Cancer Driver No 127 0.135 521 71 0.136 2
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0043066 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA4 ANXA4 P09525 Annexin A4 chr2 GO:0043066 Not Cancer Driver No 47 0.147 41 6 0.146 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 GO:0043066 Not Cancer Driver No 50 0.156 33 5 0.152 0
API5 API5 Q9BZZ5 Apoptosis inhibitor 5 chr11 GO:0043066 Not Cancer Driver No 65 0.124 92 10 0.109 0
APIP APIP Q96GX9 Methylthioribulose-1-phosphate dehydratase chr11 GO:0043066 Not Cancer Driver No 24 0.099 26 1 0.038 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0043066 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0043066 Not Cancer Driver No 67 0.194 0 0 0.0 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0043066 Not Cancer Driver No 39 0.145 4 1 0.25 0
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0043066 Census, Compendium Yes 84 0.139 181 32 0.177 0
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0043066 Not Cancer Driver No 104 0.126 92 10 0.109 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0043066 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0043066 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGAP10 ARHGAP10 A1A4S6 Rho GTPase-activating protein 10 chr4 GO:0043066 Not Cancer Driver No 100 0.127 267 41 0.154 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0043066 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0043066 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARL6IP1 ARL6IP1 Q15041 ADP-ribosylation factor-like protein 6-interacting protein 1 chr16 GO:0043066 Not Cancer Driver No 35 0.172 9 1 0.111 0
ARMC10 ARMC10 Q8N2F6 Armadillo repeat-containing protein 10 chr7 GO:0043066 Not Cancer Driver No 39 0.114 58 4 0.069 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0043066 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0043066 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0043066 Not Cancer Driver No 101 0.197 49 1 0.02 0
ASNS_ENST00000394308 ASNS P08243 Asparagine synthetase [glutamine-hydrolyzing] chr7 GO:0043066 Not Cancer Driver No 81 0.144 11 0 0.0 3
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0043066 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0043066 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF5_ENST00000595125 ATF5 Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 chr19 GO:0043066 Not Cancer Driver No 47 0.167 239 40 0.167 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0043066 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0043066 Not Cancer Driver No 63 0.178 327 55 0.168 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0043066 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0043066 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVEN AVEN Q9NQS1 Cell death regulator Aven chr15 GO:0043066 Not Cancer Driver No 39 0.108 315 33 0.105 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0043066 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0043066 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0043066 Not Cancer Driver No 42 0.167 53 13 0.245 0
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 GO:0043066 Not Cancer Driver No 52 0.136 0 0 0.0 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 GO:0043066 Not Cancer Driver No 29 0.084 195 9 0.046 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0043066 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0043066 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0043066 Not Cancer Driver No 37 0.083 63 7 0.111 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0043066 Not Cancer Driver No 98 0.087 861 79 0.092 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0043066 Census Yes 96 0.124 384 49 0.128 0
BARHL1_ENST00000542090 BARHL1 Q9BZE3 BarH-like 1 homeobox protein chr9 GO:0043066 Not Cancer Driver No 43 0.131 240 30 0.125 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0043066 Census Yes 30 0.156 39 2 0.051 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0043066 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0043066 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2A1 BCL2A1 Q16548 Bcl-2-related protein A1 chr15 GO:0043066 Not Cancer Driver No 28 0.16 0 0 0.0 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0043066 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 GO:0043066 Not Cancer Driver No 10 0.049 34 1 0.029 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 GO:0043066 Census, Compendium Yes 40 0.12 132 10 0.076 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0043066 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0043066 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0043066 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0043066 Census, Compendium Yes 134 0.19 328 67 0.204 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0043066 Not Cancer Driver No 81 0.207 0 0 0.0 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0043066 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0043066 Not Cancer Driver No 45 0.1 190 19 0.1 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0043066 Not Cancer Driver No 56 0.124 30 1 0.033 0
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0043066 Not Cancer Driver No 88 0.161 267 38 0.142 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0043066 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0043066 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0043066 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0043066 Not Cancer Driver No 20 0.141 49 6 0.122 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0043066 Census, Compendium Yes 640 0.132 1312 170 0.13 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0043066 Not Cancer Driver No 52 0.174 136 22 0.162 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 GO:0043066 Not Cancer Driver No 79 0.335 39 10 0.256 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0043066 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0043066 Census Yes 163 0.359 112 62 0.554 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0043066 Not Cancer Driver No 91 0.211 69 18 0.261 0
BNIP1_ENST00000351486 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 GO:0043066 Not Cancer Driver No 43 0.189 57 10 0.175 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 GO:0043066 Not Cancer Driver No 28 0.089 144 18 0.125 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0043066 Not Cancer Driver No 16 0.073 175 14 0.08 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0043066 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0043066 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0043066 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BTC BTC P35070 Probetacellulin chr4 GO:0043066 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0043066 Census Yes 32 0.203 7 2 0.286 0
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0043066 Not Cancer Driver No 28 0.078 234 18 0.077 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0043066 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAPN13 CAPN13 Q6MZZ7 Calpain-13 chr2 GO:0043066 Not Cancer Driver No 155 0.232 73 24 0.329 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0043066 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0043066 Not Cancer Driver No 99 0.099 296 36 0.122 11
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0043066 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0043066 Census Yes 32 0.116 62 5 0.081 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 GO:0043066 Not Cancer Driver No 73 0.103 708 73 0.103 0
CAT CAT P04040 Catalase chr11 GO:0043066 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0043066 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0043066 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 GO:0043066 Not Cancer Driver No 72 0.129 477 63 0.132 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0043066 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0043066 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0043066 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0043066 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0043066 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0043066 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCNG1_ENST00000393929 CCNG1 P51959 Cyclin-G1 chr5 GO:0043066 Not Cancer Driver No 25 0.085 0 0 0.0 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0043066 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0043066 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0043066 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0043066 Census Yes 42 0.191 18 10 0.556 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0043066 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0043066 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD44 CD44 P16070 CD44 antigen chr11 GO:0043066 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0043066 Census Yes 31 0.105 185 20 0.108 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0043066 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0043066 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0043066 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0043066 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0043066 Not Cancer Driver No 17 0.102 44 3 0.068 0
CEACAM5 CEACAM5 P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 GO:0043066 Not Cancer Driver No 135 0.192 256 48 0.188 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0043066 Not Cancer Driver No 63 0.183 110 19 0.173 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0043066 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFDP1 CFDP1 Q9UEE9 Craniofacial development protein 1 chr16 GO:0043066 Not Cancer Driver No 21 0.07 273 18 0.066 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 GO:0043066 Not Cancer Driver No 21 0.127 4 0 0.0 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0043066 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0043066 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHL1_ENST00000397491 CHL1 O00533 Neural cell adhesion molecule L1-like protein chr3 GO:0043066 Not Cancer Driver No 348 0.288 415 121 0.292 0
CHST11 CHST11 Q9NPF2 Carbohydrate sulfotransferase 11 chr12 GO:0043066 Census Yes 69 0.196 45 11 0.244 0
CIAPIN1 CIAPIN1 Q6FI81 Anamorsin chr16 GO:0043066 Not Cancer Driver No 27 0.087 119 8 0.067 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0043066 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0043066 Not Cancer Driver No 43 0.196 32 3 0.094 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0043066 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0043066 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0043066 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC5A CLEC5A Q9NY25 C-type lectin domain family 5 member A chr7 GO:0043066 Not Cancer Driver No 46 0.245 0 0 0.0 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0043066 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0043066 Not Cancer Driver No 45 0.157 16 2 0.125 16
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0043066 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0043066 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:0043066 Not Cancer Driver No 50 0.134 92 8 0.087 0
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0043066 Census Yes 258 0.174 1215 207 0.17 64
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0043066 Not Cancer Driver No 97 0.128 306 52 0.17 61
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0043066 Not Cancer Driver No 36 0.108 32 7 0.219 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0043066 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0043066 Not Cancer Driver No 85 0.117 443 54 0.122 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0043066 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0043066 Census Yes 68 0.131 372 50 0.134 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0043066 Not Cancer Driver No 51 0.121 101 7 0.069 14
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 GO:0043066 Not Cancer Driver No 34 0.197 42 11 0.262 10
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0043066 Not Cancer Driver No 22 0.126 59 11 0.186 4
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0043066 Census Yes 133 0.137 124 17 0.137 20
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0043066 Not Cancer Driver No 11 0.076 34 3 0.088 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0043066 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0043066 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0043066 Not Cancer Driver No 45 0.134 4 0 0.0 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0043066 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0043066 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0043066 Not Cancer Driver No 16 0.172 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0043066 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 GO:0043066 Not Cancer Driver No 7 0.062 0 0 0.0 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0043066 Not Cancer Driver No 193 0.135 114 11 0.096 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0043066 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0043066 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:0043066 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0043066 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0043066 Census, Compendium Yes 133 0.201 301 47 0.156 18
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0043066 Not Cancer Driver No 47 0.142 113 18 0.159 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0043066 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0043066 Not Cancer Driver No 47 0.168 0 0 0.0 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0043066 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0043066 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0043066 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0043066 Not Cancer Driver No 25 0.098 183 21 0.115 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0043066 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0043066 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0043066 Not Cancer Driver No 60 0.119 131 17 0.13 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 GO:0043066 Not Cancer Driver No 23 0.116 46 6 0.13 1
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0043066 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0043066 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0043066 Not Cancer Driver No 54 0.131 41 6 0.146 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0043066 Not Cancer Driver No 61 0.175 249 48 0.193 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0043066 Not Cancer Driver No 88 0.22 45 17 0.378 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0043066 Not Cancer Driver No 112 0.121 112 4 0.036 2
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0043066 Not Cancer Driver No 87 0.148 193 20 0.104 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0043066 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0043066 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0043066 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0043066 Not Cancer Driver No 29 0.141 46 5 0.109 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0043066 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0043066 Not Cancer Driver No 60 0.155 252 46 0.183 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0043066 Not Cancer Driver No 59 0.107 188 22 0.117 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0043066 Not Cancer Driver No 50 0.126 186 13 0.07 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0043066 Not Cancer Driver No 42 0.107 357 30 0.084 0
EN2 EN2 P19622 Homeobox protein engrailed-2 chr7 GO:0043066 Not Cancer Driver No 23 0.069 317 23 0.073 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0043066 Not Cancer Driver No 51 0.118 21 2 0.095 0
EPO EPO P01588 Erythropoietin chr7 GO:0043066 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0043066 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0043066 Census Yes 175 0.148 816 121 0.148 6
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:0043066 Not Cancer Driver No 63 0.141 373 55 0.147 0
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0043066 Not Cancer Driver No 168 0.284 341 99 0.29 15
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0043066 Not Cancer Driver No 107 0.199 204 50 0.245 0
EYA3 EYA3 Q99504 Eyes absent homolog 3 chr1 GO:0043066 Not Cancer Driver No 58 0.101 310 40 0.129 0
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 GO:0043066 Not Cancer Driver No 183 0.286 337 108 0.32 2
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0043066 Not Cancer Driver No 73 0.172 19 2 0.105 0
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0043066 Not Cancer Driver No 34 0.268 0 0 0.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0043066 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0043066 Not Cancer Driver No 37 0.117 54 11 0.204 0
FAIM_ENST00000393035 FAIM Q9NVQ4 Fas apoptotic inhibitory molecule 1 chr3 GO:0043066 Not Cancer Driver No 20 0.112 1 0 0.0 0
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0043066 Not Cancer Driver No 99 0.133 206 20 0.097 0
FANK1 FANK1 Q8TC84 Fibronectin type 3 and ankyrin repeat domains protein 1 chr10 GO:0043066 Not Cancer Driver No 65 0.188 63 13 0.206 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0043066 Census, Compendium Yes 55 0.164 62 18 0.29 22
FATE1 FATE1 Q969F0 Fetal and adult testis-expressed transcript protein chrX GO:0043066 Not Cancer Driver No 45 0.246 117 30 0.256 0
FCMR FCMR O60667 Fas apoptotic inhibitory molecule 3 chr1 GO:0043066 Not Cancer Driver No 55 0.141 229 29 0.127 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0043066 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0043066 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0043066 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0043066 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0043066 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0043066 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0043066 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0043066 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0043066 Not Cancer Driver No 81 0.179 53 8 0.151 8
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:0043066 Not Cancer Driver No 30 0.108 0 0 0.0 0
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0043066 Not Cancer Driver No 75 0.111 224 23 0.103 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0043066 Not Cancer Driver No 71 0.172 160 25 0.156 0
FLNA FLNA P21333 Filamin-A chrX GO:0043066 Census Yes 416 0.157 1456 214 0.147 28
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0043066 Census, Compendium Yes 253 0.186 259 41 0.158 13
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0043066 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0043066 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0043066 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0043066 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0043066 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0043066 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0043066 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 GO:0043066 Not Cancer Driver No 22 0.055 245 4 0.016 0
FSTL1 FSTL1 Q12841 Follistatin-related protein 1 chr3 GO:0043066 Not Cancer Driver No 41 0.133 51 7 0.137 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0043066 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0043066 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0043066 Not Cancer Driver No 55 0.093 61 0 0.0 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0043066 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0043066 Not Cancer Driver No 165 0.322 27 10 0.37 1
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0043066 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0043066 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0043066 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0043066 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0043066 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0043066 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0043066 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBE1 GBE1 Q04446 1,4-alpha-glucan-branching enzyme chr3 GO:0043066 Not Cancer Driver No 101 0.144 8 0 0.0 9
GCG GCG P01275 Pro-glucagon chr2 GO:0043066 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0043066 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0043066 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0043066 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0043066 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0043066 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:0043066 Not Cancer Driver No 176 0.447 5 2 0.4 0
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0043066 Not Cancer Driver No 50 0.145 8 0 0.0 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0043066 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0043066 Not Cancer Driver No 85 0.232 4 0 0.0 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0043066 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLO1 GLO1 Q04760 Lactoylglutathione lyase chr6 GO:0043066 Not Cancer Driver No 24 0.13 46 7 0.152 0
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0043066 Not Cancer Driver No 41 0.138 72 1 0.014 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0043066 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0043066 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0043066 Not Cancer Driver No 38 0.187 12 1 0.083 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0043066 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRIA4_ENST00000530497 GRIA4 P48058 Glutamate receptor 4 chr11 GO:0043066 Not Cancer Driver No 227 0.252 63 25 0.397 4
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0043066 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:0043066 Not Cancer Driver No 39 0.105 150 15 0.1 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0043066 Not Cancer Driver No 77 0.131 103 18 0.175 0
GRN GRN P28799 Progranulin chr17 GO:0043066 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0043066 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0043066 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0043066 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0043066 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0043066 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0043066 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0043066 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0043066 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0043066 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:0043066 Not Cancer Driver No 35 0.146 203 29 0.143 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0043066 Census Yes 38 0.097 248 17 0.069 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0043066 Not Cancer Driver No 64 0.19 179 26 0.145 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0043066 Compendium Yes 233 0.32 43 16 0.372 0
HHIP HHIP Q96QV1 Hedgehog-interacting protein chr4 GO:0043066 Not Cancer Driver No 150 0.214 73 34 0.466 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0043066 Census Yes 118 0.143 435 51 0.117 0
HIGD1A_ENST00000418900 HIGD1A Q9Y241 HIG1 domain family member 1A, mitochondrial chr3 GO:0043066 Not Cancer Driver No 17 0.183 8 0 0.0 0
HIGD2A HIGD2A Q9BW72 HIG1 domain family member 2A, mitochondrial chr5 GO:0043066 Not Cancer Driver No 9 0.085 41 4 0.098 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0043066 Not Cancer Driver No 94 0.088 524 34 0.065 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0043066 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0043066 Not Cancer Driver No 128 0.105 559 51 0.091 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0043066 Census Yes 12 0.11 109 12 0.11 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0043066 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGN5 HMGN5 P82970 High mobility group nucleosome-binding domain-containing protein 5 chrX GO:0043066 Not Cancer Driver No 27 0.096 282 27 0.096 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0043066 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0043066 Not Cancer Driver No 75 0.162 302 59 0.195 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0043066 Not Cancer Driver No 60 0.144 12 0 0.0 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0043066 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0043066 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSH2D HSH2D Q96JZ2 Hematopoietic SH2 domain-containing protein chr19 GO:0043066 Not Cancer Driver No 44 0.125 233 38 0.163 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0043066 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0043066 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0043066 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0043066 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0043066 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 GO:0043066 Not Cancer Driver No 67 0.099 283 26 0.092 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0043066 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPB6 HSPB6 O14558 Heat shock protein beta-6 chr19 GO:0043066 Not Cancer Driver No 5 0.031 56 0 0.0 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0043066 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTATIP2_ENST00000443524 HTATIP2 Q9BUP3 Oxidoreductase HTATIP2 chr11 GO:0043066 Not Cancer Driver No 22 0.091 14 0 0.0 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0043066 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0043066 Compendium Yes 44 0.096 127 9 0.071 2
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0043066 Not Cancer Driver No 132 0.132 373 47 0.126 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0043066 Not Cancer Driver No 61 0.115 251 28 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0043066 Not Cancer Driver No 20 0.129 17 6 0.353 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0043066 Not Cancer Driver No 82 0.203 41 8 0.195 0
IER3 IER3 P46695 Radiation-inducible immediate-early gene IEX-1 chr6 GO:0043066 Not Cancer Driver No 5 0.032 106 4 0.038 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0043066 Not Cancer Driver No 12 0.092 7 0 0.0 0
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 GO:0043066 Not Cancer Driver No 47 0.096 143 11 0.077 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0043066 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0043066 Not Cancer Driver No 45 0.231 87 23 0.264 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0043066 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0043066 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0043066 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0043066 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0043066 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0043066 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0043066 Census Yes 24 0.157 6 1 0.167 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0043066 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 GO:0043066 Not Cancer Driver No 81 0.147 182 33 0.181 1
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0043066 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0043066 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0043066 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0043066 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0043066 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0043066 Census, Compendium Yes 177 0.386 88 48 0.545 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0043066 Not Cancer Driver No 12 0.083 4 0 0.0 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0043066 Not Cancer Driver No 33 0.118 169 26 0.154 0
INS INS P01308 Insulin chr11 GO:0043066 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0043066 Not Cancer Driver No 18 0.137 34 12 0.353 3
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0043066 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0043066 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0043066 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0043066 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0043066 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0043066 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0043066 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPRIP_ENST00000358187 ITPRIP Q8IWB1 Inositol 1,4,5-trisphosphate receptor-interacting protein chr10 GO:0043066 Not Cancer Driver No 62 0.113 66 10 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0043066 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0043066 Census, Compendium Yes 167 0.149 63 10 0.159 7
JUN JUN P05412 Transcription factor Jun chr1 GO:0043066 Census Yes 35 0.106 281 25 0.089 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0043066 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0043066 Not Cancer Driver No 187 0.14 617 90 0.146 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0043066 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0043066 Not Cancer Driver No 68 0.313 121 43 0.355 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0043066 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0043066 Not Cancer Driver No 116 0.146 71 10 0.141 0
KITLG KITLG P21583 Kit ligand chr12 GO:0043066 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0043066 Not Cancer Driver No 83 0.136 143 17 0.119 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0043066 Census, Compendium Yes 788 4.169 7 2 0.286 27
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0043066 Not Cancer Driver No 80 0.109 113 17 0.15 2
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 GO:0043066 Not Cancer Driver No 57 0.133 179 21 0.117 4
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0043066 Not Cancer Driver No 38 0.275 90 27 0.3 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0043066 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0043066 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0043066 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0043066 Not Cancer Driver No 38 0.096 232 14 0.06 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 GO:0043066 Not Cancer Driver No 75 0.192 219 45 0.205 4
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0043066 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0043066 Not Cancer Driver No 203 0.312 291 97 0.333 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0043066 Not Cancer Driver No 55 0.161 8 0 0.0 0
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0043066 Census Yes 68 0.102 544 49 0.09 131
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0043066 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0043066 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0043066 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTF LTF P02788 Lactotransferrin chr3 GO:0043066 Not Cancer Driver No 131 0.185 21 4 0.19 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0043066 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYPD3 LYPD3 O95274 Ly6/PLAUR domain-containing protein 3 chr19 GO:0043066 Not Cancer Driver No 52 0.15 116 15 0.129 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0043066 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAEA MAEA Q7L5Y9 E3 ubiquitin-protein transferase MAEA chr4 GO:0043066 Not Cancer Driver No 58 0.146 64 5 0.078 0
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 GO:0043066 Not Cancer Driver No 126 0.29 114 35 0.307 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0043066 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAGEA4_ENST00000393921 MAGEA4 P43358 Melanoma-associated antigen 4 chrX GO:0043066 Not Cancer Driver No 104 0.328 108 35 0.324 0
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0043066 Not Cancer Driver No 118 0.188 65 7 0.108 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0043066 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0043066 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0043066 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0043066 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0043066 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0043066 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0043066 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0043066 Not Cancer Driver No 64 0.15 94 9 0.096 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0043066 Not Cancer Driver No 85 0.121 550 68 0.124 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0043066 Not Cancer Driver No 30 0.086 203 21 0.103 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0043066 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0043066 Census, Compendium Yes 56 0.114 297 37 0.125 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 GO:0043066 Census, Compendium Yes 57 0.116 202 26 0.129 1
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0043066 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0043066 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0043066 Not Cancer Driver No 92 0.195 408 81 0.199 0
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0043066 Not Cancer Driver No 175 0.175 159 31 0.195 3
MIEN1_ENST00000394231 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0043066 Not Cancer Driver No 17 0.148 37 4 0.108 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0043066 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0043066 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0043066 Not Cancer Driver No 23 0.074 64 2 0.031 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0043066 Not Cancer Driver No 149 0.2 52 12 0.231 3
MPV17L MPV17L Q2QL34 Mpv17-like protein chr16 GO:0043066 Not Cancer Driver No 16 0.082 3 0 0.0 0
MPZ MPZ P25189 Myelin protein P0 chr1 GO:0043066 Not Cancer Driver No 26 0.105 49 4 0.082 90
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0043066 Not Cancer Driver No 84 0.119 292 35 0.12 1
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0043066 Census Yes 92 0.099 37 4 0.108 70
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0043066 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0043066 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0043066 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTDH MTDH Q86UE4 Protein LYRIC chr8 GO:0043066 Not Cancer Driver No 83 0.143 516 81 0.157 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0043066 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTRNR2L12 MTRNR2L12 P0DMP1 Humanin-like 12 chr3 GO:0043066 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L4 MTRNR2L4 P0CJ71 Humanin-like 4 chr16 GO:0043066 Not Cancer Driver No 1 0.036 0 0 0.0 0
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0043066 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L7 MTRNR2L7 P0CJ74 Humanin-like 7 chr10 GO:0043066 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTRNR2L8 MTRNR2L8 P0CJ75 Humanin-like 8 chr11 GO:0043066 Not Cancer Driver No 1 0.042 0 0 0.0 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0043066 Census Yes 40 0.032 1050 19 0.018 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043066 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0043066 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 GO:0043066 Not Cancer Driver No 268 0.13 1237 176 0.142 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0043066 Not Cancer Driver No 284 0.303 853 263 0.308 0
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 GO:0043066 Not Cancer Driver No 95 0.11 115 17 0.148 0
NAA16 NAA16 Q6N069 N-alpha-acetyltransferase 16, NatA auxiliary subunit chr13 GO:0043066 Not Cancer Driver No 91 0.105 74 12 0.162 0
NAA35 NAA35 Q5VZE5 N-alpha-acetyltransferase 35, NatC auxiliary subunit chr9 GO:0043066 Not Cancer Driver No 87 0.12 120 22 0.183 0
NAA38_ENST00000575771 NAA38 Q9BRA0 N-alpha-acetyltransferase 38, NatC auxiliary subunit chr17 GO:0043066 Not Cancer Driver No 11 0.088 79 4 0.051 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0043066 Not Cancer Driver No 39 0.028 67 4 0.06 0
NAT8 NAT8 Q9UHE5 N-acetyltransferase 8 chr2 GO:0043066 Not Cancer Driver No 48 0.211 0 0 0.0 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0043066 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0043066 Not Cancer Driver No 125 0.22 129 29 0.225 1
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 GO:0043066 Not Cancer Driver No 14 0.08 46 4 0.087 2
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0043066 Not Cancer Driver No 92 0.169 285 39 0.137 12
NES NES P48681 Nestin chr1 GO:0043066 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0043066 Not Cancer Driver No 84 0.236 202 52 0.257 2
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0043066 Not Cancer Driver No 155 0.172 685 120 0.175 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0043066 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0043066 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0043066 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0043066 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX2-6 NKX2-6 A6NCS4 Homeobox protein Nkx-2.6 chr8 GO:0043066 Not Cancer Driver No 10 0.033 243 7 0.029 3
NKX3-2 NKX3-2 P78367 Homeobox protein Nkx-3.2 chr4 GO:0043066 Not Cancer Driver No 36 0.108 212 27 0.127 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0043066 Not Cancer Driver No 60 0.124 21 3 0.143 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0043066 Not Cancer Driver No 13 0.086 11 1 0.091 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0043066 Not Cancer Driver No 17 0.08 6 0 0.0 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 GO:0043066 Not Cancer Driver No 77 0.103 281 31 0.11 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0043066 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0043066 Not Cancer Driver No 20 0.096 179 17 0.095 2
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0043066 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0043066 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0043066 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0043066 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0043066 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0043066 Not Cancer Driver No 144 0.324 44 16 0.364 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0043066 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0043066 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0043066 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0043066 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 GO:0043066 Not Cancer Driver No 30 0.06 110 5 0.045 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0043066 Compendium Yes 146 0.158 211 31 0.147 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0043066 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0043066 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0043066 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0043066 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0043066 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUGGC NUGGC Q68CJ6 Nuclear GTPase SLIP-GC chr8 GO:0043066 Not Cancer Driver No 143 0.18 141 21 0.149 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0043066 Not Cancer Driver No 76 0.146 377 56 0.149 1
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0043066 Not Cancer Driver No 10 0.122 82 10 0.122 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0043066 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0043066 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0043066 Not Cancer Driver No 39 0.097 6 1 0.167 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0043066 Not Cancer Driver No 22 0.144 9 1 0.111 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0043066 Not Cancer Driver No 57 0.214 67 17 0.254 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0043066 Not Cancer Driver No 126 0.144 544 76 0.14 0
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 GO:0043066 Not Cancer Driver No 45 0.114 128 18 0.141 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX GO:0043066 Not Cancer Driver No 20 0.196 102 20 0.196 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0043066 Compendium Yes 89 0.17 242 49 0.202 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 GO:0043066 Not Cancer Driver No 58 0.098 340 33 0.097 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 GO:0043066 Census Yes 124 0.105 769 77 0.1 1
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0043066 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0043066 Not Cancer Driver No 49 0.129 28 5 0.179 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0043066 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 GO:0043066 Census Yes 97 0.192 401 77 0.192 1
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0043066 Census Yes 84 0.187 291 55 0.189 4
PCDHGC3 PCDHGC3 Q9UN70 Protocadherin gamma-C3 chr5 GO:0043066 Not Cancer Driver No 113 0.121 367 34 0.093 0
PCDHGC4 PCDHGC4 Q9Y5F7 Protocadherin gamma-C4 chr5 GO:0043066 Not Cancer Driver No 136 0.145 460 59 0.128 0
PCDHGC5 PCDHGC5 Q9Y5F6 Protocadherin gamma-C5 chr5 GO:0043066 Not Cancer Driver No 135 0.143 492 72 0.146 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0043066 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0043066 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0043066 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0043066 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0043066 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0043066 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0043066 Not Cancer Driver No 70 0.17 14 2 0.143 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0043066 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0043066 Not Cancer Driver No 37 0.228 96 24 0.25 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0043066 Not Cancer Driver No 32 0.113 238 23 0.097 0
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0043066 Not Cancer Driver No 12 0.092 35 5 0.143 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0043066 Not Cancer Driver No 13 0.129 0 0 0.0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0043066 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 GO:0043066 Not Cancer Driver No 239 0.131 835 110 0.132 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0043066 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0043066 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0043066 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0043066 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0043066 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0043066 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0043066 Census, Compendium Yes 71 0.227 27 8 0.296 0
PIM2 PIM2 Q9P1W9 Serine/threonine-protein kinase pim-2 chrX GO:0043066 Not Cancer Driver No 43 0.138 47 10 0.213 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0043066 Not Cancer Driver No 24 0.074 9 0 0.0 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0043066 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP PIP P12273 Prolactin-inducible protein chr7 GO:0043066 Not Cancer Driver No 42 0.288 0 0 0.0 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0043066 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0043066 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLAC8_ENST00000505406 PLAC8 Q9NZF1 Placenta-specific gene 8 protein chr4 GO:0043066 Not Cancer Driver No 20 0.174 7 0 0.0 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0043066 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0043066 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0043066 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0043066 Not Cancer Driver No 75 0.116 202 15 0.074 0
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0043066 Not Cancer Driver No 43 0.086 402 30 0.075 4
POU3F4_ENST00000644024 POU3F4 P49335 POU domain, class 3, transcription factor 4 chrX GO:0043066 Not Cancer Driver No 115 0.319 263 80 0.304 5
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0043066 Not Cancer Driver No 51 0.122 273 34 0.125 1
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0043066 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0043066 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0043066 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0043066 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0043066 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0043066 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0043066 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRAMEF1 PRAMEF1 O95521 PRAME family member 1 chr1 GO:0043066 Not Cancer Driver No 142 0.3 7 0 0.0 0
PRAMEF10 PRAMEF10 O60809 PRAME family member 10 chr1 GO:0043066 Not Cancer Driver No 91 0.192 7 1 0.143 0
PRAMEF11 PRAMEF11 O60813 PRAME family member 11 chr1 GO:0043066 Not Cancer Driver No 158 0.331 4 0 0.0 0
PRAMEF12 PRAMEF12 O95522 PRAME family member 12 chr1 GO:0043066 Not Cancer Driver No 122 0.253 6 6 1.0 0
PRAMEF14 PRAMEF14 Q5SWL7 PRAME family member 14 chr1 GO:0043066 Not Cancer Driver No 31 0.065 6 0 0.0 0
PRAMEF17 PRAMEF17 Q5VTA0 PRAME family member 17 chr1 GO:0043066 Not Cancer Driver No 34 0.072 10 3 0.3 0
PRAMEF2 PRAMEF2 O60811 PRAME family member 2 chr1 GO:0043066 Not Cancer Driver No 142 0.3 5 0 0.0 0
PRAMEF20 PRAMEF20 Q5VT98 PRAME family member 20 chr1 GO:0043066 Not Cancer Driver No 29 0.061 0 0 0.0 0
PRAMEF25 PRAMEF25 A6NGN4 PRAME family member 25 chr1 GO:0043066 Not Cancer Driver No 1 0.002 4 0 0.0 0
PRAMEF4 PRAMEF4 O60810 PRAME family member 4 chr1 GO:0043066 Not Cancer Driver No 135 0.282 4 3 0.75 0
PRAMEF5 PRAMEF5 Q5TYX0 PRAME family member 5 chr1 GO:0043066 Not Cancer Driver No 13 0.027 4 0 0.0 0
PRAMEF6 PRAMEF6 Q5VXH4 PRAME family member 6 chr1 GO:0043066 Not Cancer Driver No 47 0.099 4 2 0.5 0
PRAMEF7_ENST00000330881 PRAMEF7 Q5VXH5 PRAME family member 7 chr1 GO:0043066 Not Cancer Driver No 47 0.099 9 0 0.0 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:0043066 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0043066 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0043066 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0043066 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0043066 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0043066 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0043066 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0043066 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0043066 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0043066 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0043066 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0043066 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0043066 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0043066 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0043066 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0043066 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0043066 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0043066 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRLR PRLR P16471 Prolactin receptor chr5 GO:0043066 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0043066 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0043066 Not Cancer Driver No 73 0.158 41 9 0.22 36
PROK2 PROK2 Q9HC23 Prokineticin-2 chr3 GO:0043066 Not Cancer Driver No 18 0.14 23 1 0.043 6
PROP1 PROP1 O75360 Homeobox protein prophet of Pit-1 chr5 GO:0043066 Not Cancer Driver No 35 0.155 194 32 0.165 7
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0043066 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0043066 Not Cancer Driver No 68 0.152 89 16 0.18 7
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0043066 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSMG2 PSMG2 Q969U7 Proteasome assembly chaperone 2 chr18 GO:0043066 Not Cancer Driver No 19 0.072 3 0 0.0 0
PTCRA_ENST00000304672 PTCRA Q6ISU1 Pre T-cell antigen receptor alpha chr6 GO:0043066 Not Cancer Driver No 36 0.128 121 12 0.099 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0043066 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0043066 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0043066 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0043066 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0043066 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0043066 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTMA PTMA P06454 Prothymosin alpha chr2 GO:0043066 Compendium Yes 10 0.09 111 10 0.09 0
PTMS_ENST00000309083 PTMS P20962 Parathymosin chr12 GO:0043066 Not Cancer Driver No 10 0.098 102 10 0.098 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0043066 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0043066 Not Cancer Driver No 480 0.207 978 216 0.221 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0043066 Not Cancer Driver No 14 0.078 19 2 0.105 1
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0043066 Not Cancer Driver No 23 0.128 30 9 0.3 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0043066 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0043066 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0043066 Not Cancer Driver No 18 0.103 34 6 0.176 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0043066 Compendium Yes 154 0.147 181 25 0.138 3
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0043066 Census, Compendium Yes 140 0.151 282 32 0.113 22
RELA RELA Q04206 Transcription factor p65 chr11 GO:0043066 Compendium Yes 75 0.136 400 48 0.12 0
RETREG1 RETREG1 Q9H6L5 Reticulophagy regulator 1 chr5 GO:0043066 Not Cancer Driver No 48 0.097 245 21 0.086 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0043066 Not Cancer Driver No 50 0.138 150 21 0.14 0
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0043066 Not Cancer Driver No 87 0.112 461 51 0.111 0
RGN RGN Q15493 Regucalcin chrX GO:0043066 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0043066 Not Cancer Driver No 38 0.121 69 9 0.13 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0043066 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0043066 Compendium Yes 82 0.122 277 39 0.141 4
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0043066 Not Cancer Driver No 32 0.106 4 1 0.25 0
RNF157 RNF157 Q96PX1 E3 ubiquitin ligase RNF157 chr17 GO:0043066 Not Cancer Driver No 76 0.112 375 39 0.104 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0043066 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0043066 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX GO:0043066 Census, Compendium Yes 46 0.215 9 3 0.333 4
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 GO:0043066 Compendium Yes 21 0.08 85 5 0.059 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0043066 Not Cancer Driver No 38 0.153 150 25 0.167 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0043066 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0043066 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0043066 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0043066 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0043066 Not Cancer Driver No 66 0.101 115 15 0.13 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0043066 Not Cancer Driver No 116 0.188 531 103 0.194 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0043066 Not Cancer Driver No 19 0.062 168 4 0.024 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0043066 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0043066 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0043066 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINB13_ENST00000344731 SERPINB13 Q9UIV8 Serpin B13 chr18 GO:0043066 Not Cancer Driver No 84 0.215 55 16 0.291 0
SERPINB2_ENST00000299502 SERPINB2 P05120 Plasminogen activator inhibitor 2 chr18 GO:0043066 Not Cancer Driver No 100 0.241 29 7 0.241 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0043066 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0043066 Not Cancer Driver No 78 0.194 7 2 0.286 0
SET SET Q01105 Protein SET chr9 GO:0043066 Census, Compendium Yes 35 0.121 221 26 0.118 2
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0043066 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0043066 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0043066 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:0043066 Not Cancer Driver No 109 0.123 586 72 0.123 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0043066 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0043066 Not Cancer Driver No 84 0.144 397 58 0.146 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0043066 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0043066 Not Cancer Driver No 48 0.148 68 3 0.044 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0043066 Compendium Yes 172 0.135 617 73 0.118 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0043066 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0043066 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 GO:0043066 Not Cancer Driver No 41 0.132 55 7 0.127 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0043066 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX4 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0043066 Not Cancer Driver No 99 0.127 460 58 0.126 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0043066 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC25A31 SLC25A31 Q9H0C2 ADP/ATP translocase 4 chr4 GO:0043066 Not Cancer Driver No 68 0.216 8 0 0.0 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0043066 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0043066 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX GO:0043066 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0043066 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC35F6 SLC35F6 Q8N357 Solute carrier family 35 member F6 chr2 GO:0043066 Not Cancer Driver No 33 0.089 13 0 0.0 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0043066 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0043066 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0043066 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0043066 Not Cancer Driver No 89 0.109 251 29 0.116 1
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0043066 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0043066 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMO SMO Q99835 Smoothened homolog chr7 GO:0043066 Census, Compendium Yes 112 0.142 241 27 0.112 1
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0043066 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0043066 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0043066 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:0043066 Not Cancer Driver No 23 0.172 110 21 0.191 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0043066 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0043066 Not Cancer Driver No 32 0.162 61 2 0.033 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0043066 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043066 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0043066 Not Cancer Driver No 32 0.144 25 5 0.2 0
SON SON P18583 Protein SON chr21 GO:0043066 Not Cancer Driver No 234 0.096 2109 212 0.101 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0043066 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0043066 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0043066 Compendium Yes 86 0.169 495 82 0.166 18
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0043066 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0043066 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0043066 Census Yes 53 0.099 130 11 0.085 1
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0043066 Not Cancer Driver No 69 0.201 259 49 0.189 0
ST3GAL1_ENST00000522652 ST3GAL1 Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 chr8 GO:0043066 Not Cancer Driver No 51 0.15 6 0 0.0 0
ST6GAL1 ST6GAL1 P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 chr3 GO:0043066 Not Cancer Driver No 55 0.135 34 8 0.235 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0043066 Not Cancer Driver No 51 0.12 139 16 0.115 6
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0043066 Census, Compendium Yes 93 0.118 144 19 0.132 5
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 GO:0043066 Census, Compendium Yes 147 0.114 735 85 0.116 1
STK40_ENST00000373132 STK40 Q8N2I9 Serine/threonine-protein kinase 40 chr1 GO:0043066 Not Cancer Driver No 50 0.115 103 9 0.087 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0043066 Not Cancer Driver No 53 0.127 84 7 0.083 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0043066 Not Cancer Driver No 97 0.163 111 23 0.207 18
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0043066 Not Cancer Driver No 72 0.092 140 12 0.086 0
SYCP2_ENST00000371001 SYCP2 Q9BX26 Synaptonemal complex protein 2 chr20 GO:0043066 Not Cancer Driver No 247 0.161 761 121 0.159 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0043066 Not Cancer Driver No 153 0.114 830 90 0.108 2
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0043066 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0043066 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:0043066 Not Cancer Driver No 48 0.191 189 34 0.18 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 GO:0043066 Not Cancer Driver No 78 0.099 429 50 0.117 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0043066 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0043066 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0043066 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0043066 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0043066 Census Yes 30 0.263 5 1 0.2 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0043066 Not Cancer Driver No 39 0.207 25 2 0.08 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0043066 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENT5B TENT5B Q96A09 Terminal nucleotidyltransferase 5B chr1 GO:0043066 Not Cancer Driver No 52 0.122 57 6 0.105 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0043066 Census Yes 110 0.097 212 16 0.075 31
TEX11_ENST00000344304 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:0043066 Not Cancer Driver No 139 0.148 30 3 0.1 2
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0043066 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0043066 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFAP2D TFAP2D Q7Z6R9 Transcription factor AP-2-delta chr6 GO:0043066 Not Cancer Driver No 164 0.363 161 54 0.335 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0043066 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0043066 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0043066 Not Cancer Driver No 45 0.109 96 14 0.146 1
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0043066 Not Cancer Driver No 188 0.161 320 58 0.181 0
THOC6 THOC6 Q86W42 THO complex subunit 6 homolog chr16 GO:0043066 Not Cancer Driver No 49 0.144 16 4 0.25 1
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 GO:0043066 Not Cancer Driver No 16 0.139 30 5 0.167 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0043066 Not Cancer Driver No 25 0.121 0 0 0.0 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0043066 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 GO:0043066 Not Cancer Driver No 111 0.144 381 53 0.139 0
TMBIM1_ENST00000396809 TMBIM1 Q969X1 Protein lifeguard 3 chr2 GO:0043066 Not Cancer Driver No 30 0.096 83 8 0.096 0
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 GO:0043066 Not Cancer Driver No 36 0.151 3 0 0.0 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0043066 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0043066 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0043066 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 GO:0043066 Not Cancer Driver No 109 0.1 946 99 0.105 0
TMIGD1 TMIGD1 Q6UXZ0 Transmembrane and immunoglobulin domain-containing protein 1 chr17 GO:0043066 Not Cancer Driver No 37 0.141 6 1 0.167 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043066 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0043066 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFAIP8_ENST00000504771 TNFAIP8 O95379 Tumor necrosis factor alpha-induced protein 8 chr5 GO:0043066 Not Cancer Driver No 21 0.106 13 1 0.077 0
TNFRSF10D TNFRSF10D Q9UBN6 Tumor necrosis factor receptor superfamily member 10D chr8 GO:0043066 Not Cancer Driver No 51 0.132 193 28 0.145 0
TNFRSF18_ENST00000379268 TNFRSF18 Q9Y5U5 Tumor necrosis factor receptor superfamily member 18 chr1 GO:0043066 Not Cancer Driver No 22 0.091 23 1 0.043 0
TNFRSF6B TNFRSF6B O95407 Tumor necrosis factor receptor superfamily member 6B chr20 GO:0043066 Not Cancer Driver No 22 0.073 22 3 0.136 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 GO:0043066 Not Cancer Driver No 43 0.1 316 36 0.114 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0043066 Not Cancer Driver No 149 0.143 795 105 0.132 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 GO:0043066 Not Cancer Driver No 85 0.148 485 72 0.148 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0043066 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:0043066 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0043066 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0043066 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0043066 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0043066 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0043066 Not Cancer Driver No 82 0.126 87 10 0.115 3
TSC22D3_ENST00000372397 TSC22D3 Q99576 TSC22 domain family protein 3 chrX GO:0043066 Not Cancer Driver No 18 0.134 51 9 0.176 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0043066 Not Cancer Driver No 27 0.17 16 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0043066 Not Cancer Driver No 23 0.114 132 11 0.083 7
TWIST2 TWIST2 Q8WVJ9 Twist-related protein 2 chr2 GO:0043066 Not Cancer Driver No 11 0.069 90 2 0.022 4
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:0043066 Not Cancer Driver No 21 0.122 44 6 0.136 0
TXNDC5 TXNDC5 Q8NBS9 Thioredoxin domain-containing protein 5 chr6 GO:0043066 Not Cancer Driver No 47 0.109 104 12 0.115 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0043066 Not Cancer Driver No 119 0.134 197 17 0.086 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0043066 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0043066 Not Cancer Driver No 129 0.1 716 68 0.095 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 GO:0043066 Not Cancer Driver No 27 0.076 140 10 0.071 0
UCN UCN P55089 Urocortin chr2 GO:0043066 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0043066 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0043066 Not Cancer Driver No 109 0.137 141 24 0.17 0
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0043066 Not Cancer Driver No 10 0.118 0 0 0.0 1
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0043066 Not Cancer Driver No 155 0.164 117 20 0.171 0
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0043066 Not Cancer Driver No 34 0.109 96 13 0.135 1
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0043066 Not Cancer Driver No 137 0.1 425 39 0.092 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0043066 Not Cancer Driver No 38 0.134 36 4 0.111 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0043066 Not Cancer Driver No 27 0.116 41 7 0.171 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0043066 Census, Compendium Yes 142 0.667 117 36 0.308 133
VIP VIP P01282 VIP peptides chr6 GO:0043066 Not Cancer Driver No 58 0.341 77 25 0.325 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0043066 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSTM2L VSTM2L Q96N03 V-set and transmembrane domain-containing protein 2-like protein chr20 GO:0043066 Not Cancer Driver No 28 0.137 134 19 0.142 0
VTCN1 VTCN1 Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 chr1 GO:0043066 Not Cancer Driver No 43 0.152 3 2 0.667 0
WDR73 WDR73 Q6P4I2 WD repeat-containing protein 73 chr15 GO:0043066 Not Cancer Driver No 29 0.077 86 7 0.081 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0043066 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0043066 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0043066 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0043066 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043066 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0043066 Not Cancer Driver No 93 0.266 18 9 0.5 4
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0043066 Not Cancer Driver No 19 0.073 169 9 0.053 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0043066 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0043066 Not Cancer Driver No 36 0.129 9 1 0.111 2
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0043066 Not Cancer Driver No 51 0.101 489 49 0.1 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0043066 Not Cancer Driver No 49 0.132 359 47 0.131 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0043066 Not Cancer Driver No 112 0.145 136 14 0.103 1
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 GO:0043066 Not Cancer Driver No 30 0.122 81 10 0.123 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0043066 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3HC1 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 GO:0043066 Not Cancer Driver No 70 0.139 250 34 0.136 0
ZFAND6 ZFAND6 Q6FIF0 AN1-type zinc finger protein 6 chr15 GO:0043066 Not Cancer Driver No 26 0.125 140 17 0.121 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0043066 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF268_ENST00000228289 ZNF268 Q14587 Zinc finger protein 268 chr12 GO:0043066 Not Cancer Driver No 96 0.101 63 9 0.143 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0043066 Not Cancer Driver No 126 0.191 54 12 0.222 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0043066 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0043066 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0043066 Not Cancer Driver No 38 0.083 291 27 0.093 0