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Total number of protein in "GO:0042995" GO term:  254

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0042995 Not Cancer Driver No 260 0.121 402 35 0.087 1
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0042995 Not Cancer Driver No 108 0.121 195 30 0.154 6
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0042995 Not Cancer Driver No 227 0.254 131 29 0.221 9
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0042995 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0042995 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACTR3B ACTR3B Q9P1U1 Actin-related protein 3B chr7 GO:0042995 Not Cancer Driver No 55 0.132 5 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0042995 Not Cancer Driver No 64 0.092 67 4 0.06 9
AFAP1L1 AFAP1L1 Q8TED9 Actin filament-associated protein 1-like 1 chr5 GO:0042995 Not Cancer Driver No 109 0.142 402 58 0.144 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0042995 Census Yes 474 0.121 2281 268 0.117 1
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0042995 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANKK1 ANKK1 Q8NFD2 Ankyrin repeat and protein kinase domain-containing protein 1 chr11 GO:0042995 Not Cancer Driver No 103 0.135 90 7 0.078 0
ANLN ANLN Q9NQW6 Anillin chr7 GO:0042995 Not Cancer Driver No 144 0.128 767 104 0.136 2
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0042995 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0042995 Not Cancer Driver No 50 0.155 30 9 0.3 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0042995 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0042995 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARPC4_ENST00000397261 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 GO:0042995 Not Cancer Driver No 11 0.065 3 0 0.0 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0042995 Not Cancer Driver No 49 0.117 154 13 0.084 0
ASPN ASPN Q9BXN1 Asporin chr9 GO:0042995 Not Cancer Driver No 40 0.105 32 9 0.281 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0042995 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0042995 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0042995 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0042995 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX GO:0042995 Census Yes 245 0.201 328 74 0.226 2
AVIL AVIL O75366 Advillin chr12 GO:0042995 Not Cancer Driver No 91 0.111 138 17 0.123 2
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0042995 Not Cancer Driver No 65 0.11 456 42 0.092 5
BIN2_ENST00000544402 BIN2 Q9UBW5 Bridging integrator 2 chr12 GO:0042995 Not Cancer Driver No 78 0.138 357 44 0.123 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0042995 Not Cancer Driver No 40 0.126 11 0 0.0 0
C1QL1 C1QL1 O75973 C1q-related factor chr17 GO:0042995 Not Cancer Driver No 25 0.097 126 5 0.04 0
C1QTNF5_ENST00000530681 C1QTNF5 Q9BXJ0 Complement C1q tumor necrosis factor-related protein 5 chr11 GO:0042995 Not Cancer Driver No 18 0.074 128 3 0.023 1
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0042995 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0042995 Not Cancer Driver No 57 0.176 90 16 0.178 1
CACNG7 CACNG7 P62955 Voltage-dependent calcium channel gamma-7 subunit chr19 GO:0042995 Not Cancer Driver No 99 0.36 9 1 0.111 0
CAD CAD P27708 CAD protein chr2 GO:0042995 Not Cancer Driver No 287 0.129 368 52 0.141 1
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0042995 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0042995 Not Cancer Driver No 81 0.116 46 11 0.239 0
CCDC13 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 GO:0042995 Not Cancer Driver No 114 0.159 580 95 0.164 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0042995 Not Cancer Driver No 51 0.095 92 2 0.022 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0042995 Not Cancer Driver No 75 0.101 542 60 0.111 0
CDC42SE2 CDC42SE2 Q9NRR3 CDC42 small effector protein 2 chr5 GO:0042995 Not Cancer Driver No 1 0.012 57 1 0.018 0
CEP350 CEP350 Q5VT06 Centrosome-associated protein 350 chr1 GO:0042995 Not Cancer Driver No 385 0.124 2576 316 0.123 0
CFAP45 CFAP45 Q9UL16 Cilia- and flagella-associated protein 45 chr1 GO:0042995 Not Cancer Driver No 126 0.229 493 120 0.243 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0042995 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0042995 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0042995 Not Cancer Driver No 183 0.264 217 67 0.309 53
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0042995 Not Cancer Driver No 36 0.086 71 2 0.028 0
CNTNAP4 CNTNAP4 Q9C0A0 Contactin-associated protein-like 4 chr16 GO:0042995 Not Cancer Driver No 408 0.312 132 40 0.303 0
COQ6 COQ6 Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial chr14 GO:0042995 Not Cancer Driver No 58 0.124 20 2 0.1 2
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0042995 Census, Compendium Yes 66 0.095 414 28 0.068 0
CRB1 CRB1 P82279 Protein crumbs homolog 1 chr1 GO:0042995 Not Cancer Driver No 464 0.33 28 5 0.179 74
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0042995 Not Cancer Driver No 66 0.166 259 44 0.17 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0042995 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDN DDN O94850 Dendrin chr12 GO:0042995 Not Cancer Driver No 71 0.1 684 67 0.098 0
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 GO:0042995 Not Cancer Driver No 117 0.116 589 76 0.129 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0042995 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMD DMD P11532 Dystrophin chrX GO:0042995 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DNAH11 DNAH11 Q96DT5 Dynein axonemal heavy chain 11 chr7 GO:0042995 Not Cancer Driver No 885 0.196 221 36 0.163 3
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0042995 Not Cancer Driver No 88 0.22 45 17 0.378 0
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 GO:0042995 Not Cancer Driver No 151 0.107 1168 126 0.108 0
EGFLAM EGFLAM Q63HQ2 Pikachurin chr5 GO:0042995 Not Cancer Driver No 283 0.278 193 83 0.43 0
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0042995 Not Cancer Driver No 35 0.111 59 6 0.102 0
ENKUR ENKUR Q8TC29 Enkurin chr10 GO:0042995 Not Cancer Driver No 53 0.207 157 39 0.248 0
EPPK1 EPPK1 P58107 Epiplakin chr8 GO:0042995 Not Cancer Driver No 417 0.082 1336 67 0.05 0
EZR EZR P15311 Ezrin chr6 GO:0042995 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0042995 Not Cancer Driver No 55 0.139 7 2 0.286 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0042995 Not Cancer Driver No 28 0.098 10 0 0.0 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0042995 Not Cancer Driver No 75 0.144 243 38 0.156 1
FCHSD1 FCHSD1 Q86WN1 F-BAR and double SH3 domains protein 1 chr5 GO:0042995 Not Cancer Driver No 78 0.113 434 50 0.115 0
FERMT3 FERMT3 Q86UX7 Fermitin family homolog 3 chr11 GO:0042995 Not Cancer Driver No 99 0.148 108 14 0.13 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0042995 Not Cancer Driver No 49 0.148 32 7 0.219 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0042995 Not Cancer Driver No 43 0.108 272 33 0.121 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0042995 Not Cancer Driver No 151 0.13 575 82 0.143 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0042995 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0042995 Not Cancer Driver No 56 0.131 20 3 0.15 0
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 GO:0042995 Not Cancer Driver No 115 0.105 524 32 0.061 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0042995 Not Cancer Driver No 124 0.196 327 70 0.214 3
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0042995 Not Cancer Driver No 58 0.118 81 5 0.062 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0042995 Not Cancer Driver No 88 0.142 312 53 0.17 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 GO:0042995 Not Cancer Driver No 68 0.101 388 42 0.108 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0042995 Not Cancer Driver No 92 0.171 70 13 0.186 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0042995 Not Cancer Driver No 65 0.15 288 42 0.146 62
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0042995 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0042995 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0042995 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0042995 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0042995 Not Cancer Driver No 66 0.177 104 21 0.202 2
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 GO:0042995 Not Cancer Driver No 84 0.158 134 27 0.201 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0042995 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0042995 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0042995 Census Yes 323 0.367 8 3 0.375 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0042995 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0042995 Not Cancer Driver No 55 0.114 180 8 0.044 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0042995 Not Cancer Driver No 112 0.213 124 25 0.202 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0042995 Not Cancer Driver No 75 0.162 302 59 0.195 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0042995 Not Cancer Driver No 105 0.223 44 8 0.182 0
ICAM2_ENST00000579687 ICAM2 P13598 Intercellular adhesion molecule 2 chr17 GO:0042995 Not Cancer Driver No 39 0.142 19 1 0.053 0
IMPG2 IMPG2 Q9BZV3 Interphotoreceptor matrix proteoglycan 2 chr3 GO:0042995 Not Cancer Driver No 202 0.163 451 64 0.142 2
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0042995 Not Cancer Driver No 9 0.05 45 1 0.022 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0042995 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0042995 Not Cancer Driver No 103 0.129 84 10 0.119 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0042995 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0042995 Not Cancer Driver No 109 0.256 40 10 0.25 0
KCTD12 KCTD12 Q96CX2 BTB/POZ domain-containing protein KCTD12 chr13 GO:0042995 Not Cancer Driver No 15 0.046 147 4 0.027 0
KCTD16_ENST00000512467 KCTD16 Q68DU8 BTB/POZ domain-containing protein KCTD16 chr5 GO:0042995 Not Cancer Driver No 109 0.255 123 44 0.358 0
KCTD8 KCTD8 Q6ZWB6 BTB/POZ domain-containing protein KCTD8 chr4 GO:0042995 Not Cancer Driver No 149 0.315 257 90 0.35 0
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 GO:0042995 Not Cancer Driver No 240 0.148 982 137 0.14 0
KIZ KIZ Q2M2Z5 Centrosomal protein kizuna chr20 GO:0042995 Not Cancer Driver No 70 0.104 573 70 0.122 0
KLHL41 KLHL41 O60662 Kelch-like protein 41 chr2 GO:0042995 Not Cancer Driver No 69 0.114 18 2 0.111 1
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0042995 Not Cancer Driver No 24 0.076 73 5 0.068 0
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 GO:0042995 Not Cancer Driver No 107 0.147 529 71 0.134 4
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 GO:0042995 Not Cancer Driver No 43 0.111 134 16 0.119 0
LRGUK LRGUK Q96M69 Leucine-rich repeat and guanylate kinase domain-containing protein chr7 GO:0042995 Not Cancer Driver No 145 0.176 204 37 0.181 0
LRRC4B_ENST00000389201 LRRC4B Q9NT99 Leucine-rich repeat-containing protein 4B chr19 GO:0042995 Not Cancer Driver No 141 0.198 245 46 0.188 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 GO:0042995 Not Cancer Driver No 260 0.174 1212 220 0.182 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0042995 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0042995 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0042995 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0042995 Compendium Yes 367 0.201 1726 340 0.197 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0042995 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0042995 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0042995 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0042995 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0042995 Not Cancer Driver No 128 0.169 750 126 0.168 18
MCOLN1 MCOLN1 Q9GZU1 Mucolipin-1 chr19 GO:0042995 Not Cancer Driver No 77 0.133 63 15 0.238 7
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0042995 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0042995 Not Cancer Driver No 216 0.189 204 42 0.206 2
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0042995 Not Cancer Driver No 175 0.175 159 31 0.195 3
METTL5 METTL5 Q9NRN9 rRNA N6-adenosine-methyltransferase METTL5 chr2 GO:0042995 Not Cancer Driver No 19 0.091 0 0 0.0 0
MICAL3 MICAL3 Q7RTP6 [F-actin]-monooxygenase MICAL3 chr22 GO:0042995 Not Cancer Driver No 248 0.124 1264 159 0.126 0
MRI1 MRI1 Q9BV20 Methylthioribose-1-phosphate isomerase chr19 GO:0042995 Not Cancer Driver No 26 0.07 47 8 0.17 0
MSN MSN P26038 Moesin chrX GO:0042995 Census, Compendium Yes 108 0.187 286 56 0.196 1
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0042995 Not Cancer Driver No 7 0.103 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0042995 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 GO:0042995 Not Cancer Driver No 126 0.125 61 6 0.098 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0042995 Not Cancer Driver No 49 0.164 223 39 0.175 0
NDN NDN Q99608 Necdin chr15 GO:0042995 Not Cancer Driver No 123 0.383 117 42 0.359 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0042995 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0042995 Census Yes 63 0.15 254 36 0.142 3
NME9_ENST00000333911 NME9 Q86XW9 Thioredoxin domain-containing protein 6 chr3 GO:0042995 Not Cancer Driver No 51 0.155 145 27 0.186 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0042995 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPHS1 NPHS1 O60500 Nephrin chr19 GO:0042995 Not Cancer Driver No 230 0.185 484 108 0.223 62
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0042995 Not Cancer Driver No 32 0.212 71 14 0.197 1
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0042995 Not Cancer Driver No 593 0.401 301 110 0.365 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0042995 Not Cancer Driver No 46 0.087 287 19 0.066 2
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0042995 Not Cancer Driver No 156 0.149 89 16 0.18 2
OSBP2 OSBP2 Q969R2 Oxysterol-binding protein 2 chr22 GO:0042995 Not Cancer Driver No 101 0.11 432 41 0.095 0
OTOF OTOF Q9HC10 Otoferlin chr2 GO:0042995 Not Cancer Driver No 380 0.19 591 124 0.21 14
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0042995 Not Cancer Driver No 51 0.086 14 2 0.143 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0042995 Not Cancer Driver No 54 0.127 45 7 0.156 2
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0042995 Not Cancer Driver No 89 0.149 372 57 0.153 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0042995 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0042995 Not Cancer Driver No 37 0.228 96 24 0.25 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0042995 Not Cancer Driver No 109 0.408 142 62 0.437 0
PEX6 PEX6 Q13608 Peroxisome assembly factor 2 chr6 GO:0042995 Not Cancer Driver No 72 0.073 177 9 0.051 11
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0042995 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5K1B PIP5K1B O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta chr9 GO:0042995 Not Cancer Driver No 94 0.174 162 36 0.222 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0042995 Not Cancer Driver No 98 0.147 360 60 0.167 1
PIP5KL1 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 GO:0042995 Not Cancer Driver No 28 0.071 74 6 0.081 0
PITPNM3 PITPNM3 Q9BZ71 Membrane-associated phosphatidylinositol transfer protein 3 chr17 GO:0042995 Not Cancer Driver No 143 0.147 334 53 0.159 1
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0042995 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0042995 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0042995 Census, Compendium Yes 158 0.122 186 21 0.113 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0042995 Not Cancer Driver No 132 0.233 220 66 0.3 0
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0042995 Not Cancer Driver No 111 0.133 34 4 0.118 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 GO:0042995 Not Cancer Driver No 46 0.111 225 26 0.116 3
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0042995 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0042995 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0042995 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0042995 Census, Compendium Yes 315 0.241 462 107 0.232 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0042995 Not Cancer Driver No 66 0.129 356 43 0.121 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0042995 Not Cancer Driver No 26 0.122 32 5 0.156 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0042995 Not Cancer Driver No 85 0.179 227 33 0.145 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0042995 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0042995 Not Cancer Driver No 31 0.161 0 0 0.0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0042995 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0042995 Census, Compendium Yes 89 0.137 169 38 0.225 22
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0042995 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0042995 Not Cancer Driver No 52 0.265 19 2 0.105 0
RHOBTB1 RHOBTB1 O94844 Rho-related BTB domain-containing protein 1 chr10 GO:0042995 Not Cancer Driver No 95 0.136 121 19 0.157 0
RHOBTB2_ENST00000251822 RHOBTB2 Q9BYZ6 Rho-related BTB domain-containing protein 2 chr8 GO:0042995 Not Cancer Driver No 99 0.136 131 18 0.137 6
RHOBTB3 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 GO:0042995 Not Cancer Driver No 67 0.11 34 2 0.059 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0042995 Not Cancer Driver No 30 0.155 53 7 0.132 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0042995 Not Cancer Driver No 20 0.095 10 0 0.0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 GO:0042995 Not Cancer Driver No 18 0.085 10 0 0.0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0042995 Not Cancer Driver No 26 0.136 22 5 0.227 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0042995 Census Yes 41 0.215 12 3 0.25 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 GO:0042995 Not Cancer Driver No 34 0.132 63 6 0.095 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0042995 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 GO:0042995 Not Cancer Driver No 45 0.194 9 1 0.111 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0042995 Not Cancer Driver No 19 0.084 54 4 0.074 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 GO:0042995 Not Cancer Driver No 36 0.148 70 10 0.143 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0042995 Not Cancer Driver No 184 0.136 780 103 0.132 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0042995 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0042995 Not Cancer Driver No 56 0.127 142 12 0.085 0
SACS SACS Q9NZJ4 Sacsin chr13 GO:0042995 Not Cancer Driver No 683 0.149 272 41 0.151 24
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0042995 Not Cancer Driver No 100 0.14 170 35 0.206 0
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0042995 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0042995 Not Cancer Driver No 395 0.235 171 43 0.251 0
SDC3 SDC3 O75056 Syndecan-3 chr1 GO:0042995 Not Cancer Driver No 47 0.106 380 39 0.103 0
SDCCAG8 SDCCAG8 Q86SQ7 Serologically defined colon cancer antigen 8 chr1 GO:0042995 Not Cancer Driver No 110 0.154 487 73 0.15 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 GO:0042995 Not Cancer Driver No 48 0.133 187 30 0.16 0
SELPLG_ENST00000550948 SELPLG Q14242 P-selectin glycoprotein ligand 1 chr12 GO:0042995 Not Cancer Driver No 68 0.165 297 48 0.162 0
SEZ6 SEZ6 Q53EL9 Seizure protein 6 homolog chr17 GO:0042995 Not Cancer Driver No 120 0.121 345 54 0.157 0
SH3GL1 SH3GL1 Q99961 Endophilin-A2 chr19 GO:0042995 Census Yes 45 0.122 245 33 0.135 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0042995 Not Cancer Driver No 76 0.216 214 50 0.234 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 GO:0042995 Not Cancer Driver No 141 0.124 797 101 0.127 0
SH3PXD2B SH3PXD2B A1X283 SH3 and PX domain-containing protein 2B chr5 GO:0042995 Not Cancer Driver No 122 0.134 660 101 0.153 1
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0042995 Not Cancer Driver No 56 0.144 85 17 0.2 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0042995 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC17A8 SLC17A8 Q8NDX2 Vesicular glutamate transporter 3 chr12 GO:0042995 Not Cancer Driver No 134 0.228 95 30 0.316 1
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0042995 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0042995 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0042995 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC2A3 SLC2A3 P11169 Solute carrier family 2, facilitated glucose transporter member 3 chr12 GO:0042995 Not Cancer Driver No 96 0.194 33 11 0.333 0
SLC30A3 SLC30A3 Q99726 Zinc transporter 3 chr2 GO:0042995 Not Cancer Driver No 56 0.144 97 18 0.186 0
SLC4A10 SLC4A10 Q6U841 Sodium-driven chloride bicarbonate exchanger chr2 GO:0042995 Not Cancer Driver No 221 0.198 340 68 0.2 0
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0042995 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC6A17 SLC6A17 Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 GO:0042995 Not Cancer Driver No 119 0.164 67 10 0.149 2
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0042995 Not Cancer Driver No 70 0.14 15 2 0.133 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0042995 Not Cancer Driver No 33 0.082 91 13 0.143 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0042995 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0042995 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0042995 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 GO:0042995 Not Cancer Driver No 315 0.127 980 114 0.116 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0042995 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0042995 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0042995 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0042995 Not Cancer Driver No 328 0.153 562 70 0.125 7
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0042995 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0042995 Not Cancer Driver No 48 0.189 0 0 0.0 21
SVIL SVIL O95425 Supervillin chr10 GO:0042995 Not Cancer Driver No 308 0.139 1423 192 0.135 0
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0042995 Not Cancer Driver No 189 0.126 545 70 0.128 0
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0042995 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0042995 Not Cancer Driver No 60 0.155 110 11 0.1 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0042995 Not Cancer Driver No 63 0.156 132 25 0.189 0
THSD7A THSD7A Q9UPZ6 Thrombospondin type-1 domain-containing protein 7A chr7 GO:0042995 Not Cancer Driver No 408 0.246 224 74 0.33 0
TICAM2 TICAM2 Q86XR7 TIR domain-containing adapter molecule 2 chr5 GO:0042995 Not Cancer Driver No 35 0.149 88 10 0.114 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0042995 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0042995 Not Cancer Driver No 108 0.138 0 0 0.0 0
TMEM50A TMEM50A O95807 Transmembrane protein 50A chr1 GO:0042995 Not Cancer Driver No 24 0.153 0 0 0.0 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0042995 Not Cancer Driver No 426 0.328 637 231 0.363 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0042995 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 GO:0042995 Not Cancer Driver No 210 0.402 33 13 0.394 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0042995 Not Cancer Driver No 115 0.152 173 30 0.173 0
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0042995 Not Cancer Driver No 400 0.129 1052 118 0.112 10
TRIP10 TRIP10 Q15642 Cdc42-interacting protein 4 chr19 GO:0042995 Not Cancer Driver No 72 0.12 460 61 0.133 0
TTC25 ODAD4 Q96NG3 Outer dynein arm-docking complex subunit 4 chr17 GO:0042995 Not Cancer Driver No 62 0.092 264 25 0.095 0
TULP1 TULP1 O00294 Tubby-related protein 1 chr6 GO:0042995 Not Cancer Driver No 101 0.186 377 76 0.202 12
UTRN UTRN P46939 Utrophin chr6 GO:0042995 Not Cancer Driver No 476 0.139 1283 183 0.143 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0042995 Not Cancer Driver No 38 0.173 4 1 0.25 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0042995 Not Cancer Driver No 66 0.109 30 7 0.233 2
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 GO:0042995 Not Cancer Driver No 19 0.096 21 2 0.095 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 GO:0042995 Not Cancer Driver No 84 0.133 49 9 0.184 0
ZNRF2 ZNRF2 Q8NHG8 E3 ubiquitin-protein ligase ZNRF2 chr7 GO:0042995 Not Cancer Driver No 12 0.05 147 0 0.0 0