Total number of protein in "GO:0042770" GO term: 62
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0042770 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ACER2 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0042770 | Not Cancer Driver | No | 27 | 0.098 | 0 | 0 | 0.0 | 0 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0042770 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0042770 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0042770 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BATF | BATF | Q16520 | Basic leucine zipper transcriptional factor ATF-like | chr14 | GO:0042770 | Not Cancer Driver | No | 28 | 0.224 | 119 | 25 | 0.21 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0042770 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0042770 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BRCA2_ENST00000544455 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | GO:0042770 | Census, Compendium | Yes | 457 | 0.134 | 1542 | 225 | 0.146 | 46 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0042770 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0042770 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0042770 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0042770 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0042770 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0042770 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CEP63 | CEP63 | Q96MT8 | Centrosomal protein of 63 kDa | chr3 | GO:0042770 | Not Cancer Driver | No | 100 | 0.142 | 507 | 68 | 0.134 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0042770 | Census, Compendium | Yes | 335 | 0.617 | 157 | 130 | 0.828 | 13 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0042770 | Not Cancer Driver | No | 35 | 0.176 | 45 | 5 | 0.111 | 1 |
| E2F7 | E2F7 | Q96AV8 | Transcription factor E2F7 | chr12 | GO:0042770 | Not Cancer Driver | No | 122 | 0.134 | 554 | 70 | 0.126 | 0 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0042770 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FOXM1_ENST00000359843 | FOXM1 | Q08050 | Forkhead box protein M1 | chr12 | GO:0042770 | Not Cancer Driver | No | 97 | 0.127 | 601 | 73 | 0.121 | 0 |
| FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0042770 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
| GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0042770 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
| GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0042770 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
| GML | GML | Q99445 | Glycosyl-phosphatidylinositol-anchored molecule-like protein | chr8 | GO:0042770 | Not Cancer Driver | No | 49 | 0.31 | 12 | 6 | 0.5 | 0 |
| GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0042770 | Not Cancer Driver | No | 28 | 0.129 | 10 | 1 | 0.1 | 0 |
| GTSE1 | GTSE1 | Q9NYZ3 | G2 and S phase-expressed protein 1 | chr22 | GO:0042770 | Not Cancer Driver | No | 91 | 0.126 | 660 | 85 | 0.129 | 0 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0042770 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| ING4 | ING4 | Q9UNL4 | Inhibitor of growth protein 4 | chr12 | GO:0042770 | Not Cancer Driver | No | 31 | 0.124 | 108 | 15 | 0.139 | 0 |
| KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0042770 | Not Cancer Driver | No | 65 | 0.127 | 173 | 21 | 0.121 | 3 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0042770 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0042770 | Not Cancer Driver | No | 39 | 0.108 | 25 | 1 | 0.04 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0042770 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MDM4 | MDM4 | O15151 | Protein Mdm4 | chr1 | GO:0042770 | Census, Compendium | Yes | 57 | 0.116 | 202 | 26 | 0.129 | 1 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | GO:0042770 | Not Cancer Driver | No | 4 | 0.035 | 0 | 0 | 0.0 | 0 |
| MUC1_ENST00000611571 | MUC1 | P15941 | Mucin-1 | chr1 | GO:0042770 | Census | Yes | 40 | 0.032 | 1050 | 19 | 0.018 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | GO:0042770 | Not Cancer Driver | No | 176 | 0.136 | 342 | 41 | 0.12 | 3 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0042770 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| NDRG1 | NDRG1 | Q92597 | Protein NDRG1 | chr8 | GO:0042770 | Census | Yes | 66 | 0.168 | 140 | 22 | 0.157 | 0 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0042770 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PIDD1 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0042770 | Not Cancer Driver | No | 93 | 0.102 | 137 | 14 | 0.102 | 0 |
| PLK2 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0042770 | Not Cancer Driver | No | 92 | 0.134 | 178 | 21 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0042770 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0042770 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPM1D | PPM1D | O15297 | Protein phosphatase 1D | chr17 | GO:0042770 | Census, Compendium | Yes | 54 | 0.089 | 370 | 32 | 0.086 | 0 |
| PRAP1 | PRAP1 | Q96NZ9 | Proline-rich acidic protein 1 | chr10 | GO:0042770 | Not Cancer Driver | No | 14 | 0.093 | 124 | 13 | 0.105 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0042770 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| RFWD3 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0042770 | Census | Yes | 68 | 0.088 | 318 | 30 | 0.094 | 1 |
| RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0042770 | Not Cancer Driver | No | 28 | 0.104 | 114 | 16 | 0.14 | 0 |
| RPL26 | RPL26 | P61254 | 60S ribosomal protein L26 | chr17 | GO:0042770 | Not Cancer Driver | No | 16 | 0.11 | 114 | 13 | 0.114 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0042770 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| RPS6KA6_ENST00000262752 | RPS6KA6 | Q9UK32 | Ribosomal protein S6 kinase alpha-6 | chrX | GO:0042770 | Not Cancer Driver | No | 180 | 0.242 | 136 | 36 | 0.265 | 0 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | GO:0042770 | Not Cancer Driver | No | 56 | 0.124 | 290 | 35 | 0.121 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0042770 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | GO:0042770 | Not Cancer Driver | No | 136 | 0.155 | 680 | 101 | 0.149 | 0 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0042770 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0042770 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0042770 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TRIAP1 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0042770 | Not Cancer Driver | No | 9 | 0.118 | 20 | 1 | 0.05 | 0 |
| USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0042770 | Not Cancer Driver | No | 92 | 0.115 | 425 | 49 | 0.115 | 0 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0042770 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0042770 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |