Total number of protein in "GO:0042632" GO term: 83
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA1 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | GO:0042632 | Not Cancer Driver | No | 284 | 0.126 | 245 | 40 | 0.163 | 31 |
| ABCA2_ENST00000371605 | ABCA2 | Q9BZC7 | ATP-binding cassette sub-family A member 2 | chr9 | GO:0042632 | Not Cancer Driver | No | 240 | 0.099 | 497 | 44 | 0.089 | 0 |
| ABCA5 | ABCA5 | Q8WWZ7 | Cholesterol transporter ABCA5 | chr17 | GO:0042632 | Not Cancer Driver | No | 214 | 0.13 | 52 | 5 | 0.096 | 0 |
| ABCB11 | ABCB11 | O95342 | Bile salt export pump | chr2 | GO:0042632 | Not Cancer Driver | No | 233 | 0.176 | 124 | 24 | 0.194 | 21 |
| ABCG1 | ABCG1 | P45844 | ATP-binding cassette sub-family G member 1 | chr21 | GO:0042632 | Not Cancer Driver | No | 104 | 0.153 | 32 | 5 | 0.156 | 0 |
| ABCG4 | ABCG4 | Q9H172 | ATP-binding cassette sub-family G member 4 | chr11 | GO:0042632 | Not Cancer Driver | No | 122 | 0.189 | 29 | 7 | 0.241 | 0 |
| ABCG5_ENST00000405322 | ABCG5 | Q9H222 | ATP-binding cassette sub-family G member 5 | chr2 | GO:0042632 | Not Cancer Driver | No | 77 | 0.118 | 43 | 8 | 0.186 | 6 |
| ABCG8 | ABCG8 | Q9H221 | ATP-binding cassette sub-family G member 8 | chr2 | GO:0042632 | Not Cancer Driver | No | 137 | 0.204 | 40 | 8 | 0.2 | 10 |
| ACSM1_ENST00000520010 | ACSM1 | Q08AH1 | Acyl-coenzyme A synthetase ACSM1, mitochondrial | chr16 | GO:0042632 | Not Cancer Driver | No | 134 | 0.232 | 64 | 16 | 0.25 | 0 |
| ACSM3 | ACSM3 | Q53FZ2 | Acyl-coenzyme A synthetase ACSM3, mitochondrial | chr16 | GO:0042632 | Not Cancer Driver | No | 95 | 0.162 | 79 | 8 | 0.101 | 0 |
| AKR1C1 | AKR1C1 | Q04828 | Aldo-keto reductase family 1 member C1 | chr10 | GO:0042632 | Not Cancer Driver | No | 56 | 0.173 | 1 | 0 | 0.0 | 0 |
| ANGPTL3 | ANGPTL3 | Q9Y5C1 | Angiopoietin-related protein 3 | chr1 | GO:0042632 | Not Cancer Driver | No | 52 | 0.113 | 154 | 26 | 0.169 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0042632 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| APOA2 | APOA2 | P02652 | Apolipoprotein A-II | chr1 | GO:0042632 | Not Cancer Driver | No | 13 | 0.13 | 0 | 0 | 0.0 | 0 |
| APOA4 | APOA4 | P06727 | Apolipoprotein A-IV | chr11 | GO:0042632 | Not Cancer Driver | No | 77 | 0.194 | 298 | 65 | 0.218 | 0 |
| APOA5 | APOA5 | Q6Q788 | Apolipoprotein A-V | chr11 | GO:0042632 | Not Cancer Driver | No | 51 | 0.139 | 178 | 26 | 0.146 | 0 |
| APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | GO:0042632 | Not Cancer Driver | No | 1022 | 0.224 | 315 | 72 | 0.229 | 3 |
| APOC2 | APOC2 | P02655 | Apolipoprotein C-II | chr19 | GO:0042632 | Not Cancer Driver | No | 8 | 0.079 | 14 | 2 | 0.143 | 1 |
| APOC3 | APOC3 | P02656 | Apolipoprotein C-III | chr11 | GO:0042632 | Not Cancer Driver | No | 14 | 0.141 | 12 | 2 | 0.167 | 1 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0042632 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| APOM | APOM | O95445 | Apolipoprotein M | chr6 | GO:0042632 | Not Cancer Driver | No | 14 | 0.074 | 27 | 1 | 0.037 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0042632 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0042632 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CES1_ENST00000361503 | CES1 | P23141 | Liver carboxylesterase 1 | chr16 | GO:0042632 | Not Cancer Driver | No | 138 | 0.243 | 41 | 2 | 0.049 | 0 |
| CETP | CETP | P11597 | Cholesteryl ester transfer protein | chr16 | GO:0042632 | Not Cancer Driver | No | 58 | 0.118 | 0 | 0 | 0.0 | 3 |
| CNBP_ENST00000422453 | CNBP | P62633 | CCHC-type zinc finger nucleic acid binding protein | chr3 | GO:0042632 | Census | Yes | 11 | 0.062 | 19 | 0 | 0.0 | 0 |
| COMMD9 | COMMD9 | Q9P000 | COMM domain-containing protein 9 | chr11 | GO:0042632 | Not Cancer Driver | No | 25 | 0.126 | 0 | 0 | 0.0 | 0 |
| CYP39A1 | CYP39A1 | Q9NYL5 | 24-hydroxycholesterol 7-alpha-hydroxylase | chr6 | GO:0042632 | Not Cancer Driver | No | 61 | 0.13 | 3 | 0 | 0.0 | 0 |
| CYP7A1 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0042632 | Not Cancer Driver | No | 109 | 0.216 | 48 | 8 | 0.167 | 0 |
| CYP7B1 | CYP7B1 | O75881 | Cytochrome P450 7B1 | chr8 | GO:0042632 | Not Cancer Driver | No | 133 | 0.263 | 0 | 0 | 0.0 | 11 |
| DGAT2 | DGAT2 | Q96PD7 | Diacylglycerol O-acyltransferase 2 | chr11 | GO:0042632 | Not Cancer Driver | No | 56 | 0.144 | 17 | 2 | 0.118 | 0 |
| DISP3 | DISP3 | Q9P2K9 | Protein dispatched homolog 3 | chr1 | GO:0042632 | Not Cancer Driver | No | 320 | 0.23 | 172 | 44 | 0.256 | 0 |
| EHD1_ENST00000359393 | EHD1 | Q9H4M9 | EH domain-containing protein 1 | chr11 | GO:0042632 | Not Cancer Driver | No | 72 | 0.135 | 90 | 12 | 0.133 | 0 |
| EPHX2 | EPHX2 | P34913 | Bifunctional epoxide hydrolase 2 | chr8 | GO:0042632 | Not Cancer Driver | No | 78 | 0.141 | 26 | 3 | 0.115 | 0 |
| FABP3 | FABP3 | P05413 | Fatty acid-binding protein, heart | chr1 | GO:0042632 | Not Cancer Driver | No | 22 | 0.165 | 3 | 0 | 0.0 | 0 |
| FABP4 | FABP4 | P15090 | Fatty acid-binding protein, adipocyte | chr8 | GO:0042632 | Not Cancer Driver | No | 14 | 0.106 | 4 | 0 | 0.0 | 0 |
| FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0042632 | Census, Compendium | Yes | 113 | 0.141 | 162 | 28 | 0.173 | 0 |
| G6PC | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0042632 | Not Cancer Driver | No | 67 | 0.188 | 0 | 0 | 0.0 | 54 |
| GPIHBP1 | GPIHBP1 | Q8IV16 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | chr8 | GO:0042632 | Not Cancer Driver | No | 26 | 0.141 | 82 | 15 | 0.183 | 10 |
| GRAMD1B_ENST00000529750 | GRAMD1B | Q3KR37 | Protein Aster-B | chr11 | GO:0042632 | Not Cancer Driver | No | 140 | 0.19 | 335 | 69 | 0.206 | 0 |
| HDAC9_ENST00000432645 | HDAC9 | Q9UKV0 | Histone deacetylase 9 | chr7 | GO:0042632 | Not Cancer Driver | No | 286 | 0.283 | 631 | 178 | 0.282 | 0 |
| HNF4A | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | GO:0042632 | Not Cancer Driver | No | 135 | 0.285 | 127 | 48 | 0.378 | 5 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0042632 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| INSIG1 | INSIG1 | O15503 | Insulin-induced gene 1 protein | chr7 | GO:0042632 | Not Cancer Driver | No | 37 | 0.134 | 43 | 1 | 0.023 | 0 |
| LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | GO:0042632 | Not Cancer Driver | No | 13 | 0.081 | 96 | 7 | 0.073 | 0 |
| LCAT | LCAT | P04180 | Phosphatidylcholine-sterol acyltransferase | chr16 | GO:0042632 | Not Cancer Driver | No | 43 | 0.098 | 28 | 2 | 0.071 | 34 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0042632 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0042632 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LIMA1_ENST00000341247 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | GO:0042632 | Not Cancer Driver | No | 88 | 0.116 | 687 | 81 | 0.118 | 0 |
| LIPC_ENST00000356113 | LIPC | P11150 | Hepatic triacylglycerol lipase | chr15 | GO:0042632 | Not Cancer Driver | No | 91 | 0.182 | 17 | 3 | 0.176 | 2 |
| LIPG | LIPG | Q9Y5X9 | Endothelial lipase | chr18 | GO:0042632 | Not Cancer Driver | No | 90 | 0.18 | 59 | 7 | 0.119 | 0 |
| LPL | LPL | P06858 | Lipoprotein lipase | chr8 | GO:0042632 | Not Cancer Driver | No | 94 | 0.198 | 23 | 3 | 0.13 | 70 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0042632 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| LRP5L_ENST00000402785 | LRP5L | A4QPB2 | Low-density lipoprotein receptor-related protein 5-like protein | chr22 | GO:0042632 | Not Cancer Driver | No | 38 | 0.151 | 39 | 5 | 0.128 | 0 |
| MALL | MALL | Q13021 | MAL-like protein | chr2 | GO:0042632 | Not Cancer Driver | No | 20 | 0.131 | 0 | 0 | 0.0 | 0 |
| MALRD1 | MALRD1 | Q5VYJ5 | MAM and LDL-receptor class A domain-containing protein 1 | chr10 | GO:0042632 | Not Cancer Driver | No | 35 | 0.016 | 130 | 0 | 0.0 | 0 |
| MED13 | MED13 | Q9UHV7 | Mediator of RNA polymerase II transcription subunit 13 | chr17 | GO:0042632 | Not Cancer Driver | No | 288 | 0.132 | 905 | 127 | 0.14 | 3 |
| MTTP_ENST00000265517 | MTTP | P55157 | Microsomal triglyceride transfer protein large subunit | chr4 | GO:0042632 | Not Cancer Driver | No | 165 | 0.185 | 47 | 11 | 0.234 | 8 |
| MYLIP | MYLIP | Q8WY64 | E3 ubiquitin-protein ligase MYLIP | chr6 | GO:0042632 | Not Cancer Driver | No | 56 | 0.126 | 11 | 2 | 0.182 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0042632 | Not Cancer Driver | No | 155 | 0.121 | 24 | 0 | 0.0 | 150 |
| NPC2 | NPC2 | P61916 | NPC intracellular cholesterol transporter 2 | chr14 | GO:0042632 | Not Cancer Driver | No | 8 | 0.053 | 0 | 0 | 0.0 | 7 |
| NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0042632 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
| NR1H2_ENST00000593926 | NR1H2 | P55055 | Oxysterols receptor LXR-beta | chr19 | GO:0042632 | Not Cancer Driver | No | 56 | 0.122 | 179 | 30 | 0.168 | 0 |
| NR1H3_ENST00000467728 | NR1H3 | Q13133 | Oxysterols receptor LXR-alpha | chr11 | GO:0042632 | Not Cancer Driver | No | 56 | 0.125 | 146 | 13 | 0.089 | 0 |
| NR1H4 | NR1H4 | Q96RI1 | Bile acid receptor | chr12 | GO:0042632 | Not Cancer Driver | No | 111 | 0.228 | 78 | 18 | 0.231 | 0 |
| NR5A2 | NR5A2 | O00482 | Nuclear receptor subfamily 5 group A member 2 | chr1 | GO:0042632 | Not Cancer Driver | No | 126 | 0.233 | 154 | 35 | 0.227 | 0 |
| NUS1 | NUS1 | Q96E22 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | chr6 | GO:0042632 | Not Cancer Driver | No | 21 | 0.072 | 13 | 0 | 0.0 | 1 |
| PCSK9 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0042632 | Not Cancer Driver | No | 86 | 0.124 | 148 | 27 | 0.182 | 9 |
| PLA2G10 | PLA2G10 | O15496 | Group 10 secretory phospholipase A2 | chr16 | GO:0042632 | Not Cancer Driver | No | 5 | 0.03 | 0 | 0 | 0.0 | 0 |
| PLA2G12B | PLA2G12B | Q9BX93 | Group XIIB secretory phospholipase A2-like protein | chr10 | GO:0042632 | Not Cancer Driver | No | 30 | 0.154 | 15 | 2 | 0.133 | 0 |
| PLSCR3 | PLSCR3 | Q9NRY6 | Phospholipid scramblase 3 | chr17 | GO:0042632 | Not Cancer Driver | No | 30 | 0.102 | 62 | 5 | 0.081 | 0 |
| RALY | RALY | Q9UKM9 | RNA-binding protein Raly | chr20 | GO:0042632 | Not Cancer Driver | No | 58 | 0.19 | 187 | 32 | 0.171 | 0 |
| RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0042632 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |
| SCARB1_ENST00000415380 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0042632 | Not Cancer Driver | No | 53 | 0.096 | 6 | 1 | 0.167 | 0 |
| SEC24A | SEC24A | O95486 | Protein transport protein Sec24A | chr5 | GO:0042632 | Not Cancer Driver | No | 113 | 0.103 | 407 | 49 | 0.12 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0042632 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SOAT1 | SOAT1 | P35610 | Sterol O-acyltransferase 1 | chr1 | GO:0042632 | Not Cancer Driver | No | 73 | 0.133 | 49 | 4 | 0.082 | 0 |
| SOAT2 | SOAT2 | O75908 | Sterol O-acyltransferase 2 | chr12 | GO:0042632 | Not Cancer Driver | No | 69 | 0.132 | 67 | 4 | 0.06 | 0 |
| SREBF2 | SREBF2 | Q12772 | Sterol regulatory element-binding protein 2 | chr22 | GO:0042632 | Not Cancer Driver | No | 124 | 0.109 | 357 | 43 | 0.12 | 0 |
| TMEM97 | TMEM97 | Q5BJF2 | Sigma intracellular receptor 2 | chr17 | GO:0042632 | Not Cancer Driver | No | 16 | 0.091 | 0 | 0 | 0.0 | 0 |
| TSKU_ENST00000333090 | TSKU | Q8WUA8 | Tsukushi | chr11 | GO:0042632 | Not Cancer Driver | No | 53 | 0.15 | 44 | 6 | 0.136 | 0 |
| TTC39B | TTC39B | Q5VTQ0 | Tetratricopeptide repeat protein 39B | chr9 | GO:0042632 | Not Cancer Driver | No | 55 | 0.081 | 62 | 2 | 0.032 | 0 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0042632 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |