Total number of protein in "GO:0042593" GO term: 178
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC8_ENST00000389817 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0042593 | Not Cancer Driver | No | 255 | 0.161 | 138 | 23 | 0.167 | 97 |
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0042593 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACSM2A_ENST00000219054 | ACSM2A | Q08AH3 | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | chr16 | GO:0042593 | Not Cancer Driver | No | 200 | 0.347 | 48 | 24 | 0.5 | 0 |
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0042593 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| ADGRF5_ENST00000265417 | ADGRF5 | Q8IZF2 | Adhesion G protein-coupled receptor F5 | chr6 | GO:0042593 | Not Cancer Driver | No | 255 | 0.189 | 53 | 11 | 0.208 | 0 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0042593 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| ADIPOR1 | ADIPOR1 | Q96A54 | Adiponectin receptor protein 1 | chr1 | GO:0042593 | Not Cancer Driver | No | 63 | 0.168 | 69 | 10 | 0.145 | 0 |
| ADIPOR2 | ADIPOR2 | Q86V24 | Adiponectin receptor protein 2 | chr12 | GO:0042593 | Not Cancer Driver | No | 44 | 0.114 | 82 | 7 | 0.085 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0042593 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0042593 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ALOX5 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0042593 | Not Cancer Driver | No | 129 | 0.191 | 16 | 2 | 0.125 | 0 |
| APPL2_ENST00000258530 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:0042593 | Not Cancer Driver | No | 70 | 0.105 | 149 | 14 | 0.094 | 0 |
| AQP4 | AQP4 | P55087 | Aquaporin-4 | chr18 | GO:0042593 | Not Cancer Driver | No | 50 | 0.155 | 30 | 9 | 0.3 | 0 |
| ASPSCR1_ENST00000306739 | ASPSCR1 | Q9BZE9 | Tether containing UBX domain for GLUT4 | chr17 | GO:0042593 | Census | Yes | 72 | 0.13 | 298 | 49 | 0.164 | 0 |
| BACE2 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | GO:0042593 | Not Cancer Driver | No | 61 | 0.118 | 23 | 2 | 0.087 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0042593 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BHLHA15 | BHLHA15 | Q7RTS1 | Class A basic helix-loop-helix protein 15 | chr7 | GO:0042593 | Not Cancer Driver | No | 12 | 0.063 | 183 | 12 | 0.066 | 0 |
| CARTPT | CARTPT | Q16568 | Cocaine- and amphetamine-regulated transcript protein | chr5 | GO:0042593 | Not Cancer Driver | No | 18 | 0.155 | 0 | 0 | 0.0 | 0 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0042593 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0042593 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CCN4 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0042593 | Not Cancer Driver | No | 93 | 0.253 | 20 | 8 | 0.4 | 0 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0042593 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CMA1 | CMA1 | P23946 | Chymase | chr14 | GO:0042593 | Not Cancer Driver | No | 47 | 0.19 | 9 | 1 | 0.111 | 0 |
| CNR1_ENST00000549890 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0042593 | Not Cancer Driver | No | 129 | 0.273 | 9 | 1 | 0.111 | 0 |
| CPB2_ENST00000645658 | CPB2 | Q96IY4 | Carboxypeptidase B2 | chr13 | GO:0042593 | Not Cancer Driver | No | 59 | 0.139 | 2 | 0 | 0.0 | 0 |
| CRTC2 | CRTC2 | Q53ET0 | CREB-regulated transcription coactivator 2 | chr1 | GO:0042593 | Not Cancer Driver | No | 92 | 0.133 | 674 | 88 | 0.131 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0042593 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0042593 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| CSMD1 | CSMD1 | Q96PZ7 | CUB and sushi domain-containing protein 1 | chr8 | GO:0042593 | Not Cancer Driver | No | 1236 | 0.347 | 234 | 76 | 0.325 | 0 |
| CSRP3 | CSRP3 | P50461 | Cysteine and glycine-rich protein 3 | chr11 | GO:0042593 | Not Cancer Driver | No | 25 | 0.129 | 31 | 1 | 0.032 | 2 |
| CYB5R4 | CYB5R4 | Q7L1T6 | Cytochrome b5 reductase 4 | chr6 | GO:0042593 | Not Cancer Driver | No | 73 | 0.14 | 56 | 10 | 0.179 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0042593 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0042593 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP7A1 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0042593 | Not Cancer Driver | No | 109 | 0.216 | 48 | 8 | 0.167 | 0 |
| DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0042593 | Not Cancer Driver | No | 125 | 0.203 | 71 | 17 | 0.239 | 3 |
| DHPS | DHPS | P49366 | Deoxyhypusine synthase | chr19 | GO:0042593 | Not Cancer Driver | No | 52 | 0.141 | 69 | 4 | 0.058 | 1 |
| DUPD1 | DUSP29 | Q68J44 | Dual specificity phosphatase 29 | chr10 | GO:0042593 | Not Cancer Driver | No | 47 | 0.214 | 55 | 7 | 0.127 | 0 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0042593 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0042593 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
| FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | GO:0042593 | Not Cancer Driver | No | 15 | 0.111 | 4 | 4 | 1.0 | 0 |
| FAM3B | FAM3B | P58499 | Protein FAM3B | chr21 | GO:0042593 | Not Cancer Driver | No | 30 | 0.128 | 37 | 5 | 0.135 | 0 |
| FFAR1 | FFAR1 | O14842 | Free fatty acid receptor 1 | chr19 | GO:0042593 | Not Cancer Driver | No | 45 | 0.15 | 2 | 0 | 0.0 | 0 |
| FFAR2 | FFAR2 | O15552 | Free fatty acid receptor 2 | chr19 | GO:0042593 | Not Cancer Driver | No | 49 | 0.148 | 32 | 7 | 0.219 | 0 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0042593 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0042593 | Census, Compendium | Yes | 113 | 0.141 | 162 | 28 | 0.173 | 0 |
| FOXA1 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | GO:0042593 | Census, Compendium | Yes | 100 | 0.212 | 295 | 53 | 0.18 | 0 |
| FOXA3 | FOXA3 | P55318 | Hepatocyte nuclear factor 3-gamma | chr19 | GO:0042593 | Not Cancer Driver | No | 62 | 0.177 | 232 | 40 | 0.172 | 0 |
| FOXK1 | FOXK1 | P85037 | Forkhead box protein K1 | chr7 | GO:0042593 | Not Cancer Driver | No | 97 | 0.132 | 511 | 65 | 0.127 | 0 |
| FOXK2 | FOXK2 | Q01167 | Forkhead box protein K2 | chr17 | GO:0042593 | Not Cancer Driver | No | 79 | 0.12 | 548 | 64 | 0.117 | 0 |
| FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0042593 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
| FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0042593 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
| G6PC | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0042593 | Not Cancer Driver | No | 67 | 0.188 | 0 | 0 | 0.0 | 54 |
| G6PC2 | G6PC2 | Q9NQR9 | Glucose-6-phosphatase 2 | chr2 | GO:0042593 | Not Cancer Driver | No | 68 | 0.192 | 0 | 0 | 0.0 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0042593 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0042593 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GCG | GCG | P01275 | Pro-glucagon | chr2 | GO:0042593 | Not Cancer Driver | No | 49 | 0.272 | 82 | 22 | 0.268 | 0 |
| GCGR | GCGR | P47871 | Glucagon receptor | chr17 | GO:0042593 | Not Cancer Driver | No | 16 | 0.034 | 56 | 2 | 0.036 | 4 |
| GCKR | GCKR | Q14397 | Glucokinase regulatory protein | chr2 | GO:0042593 | Not Cancer Driver | No | 98 | 0.157 | 85 | 27 | 0.318 | 0 |
| GCK_ENST00000403799 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0042593 | Not Cancer Driver | No | 88 | 0.189 | 73 | 14 | 0.192 | 107 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0042593 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GCLM | GCLM | P48507 | Glutamate--cysteine ligase regulatory subunit | chr1 | GO:0042593 | Not Cancer Driver | No | 32 | 0.117 | 31 | 3 | 0.097 | 0 |
| GHRHR | GHRHR | Q02643 | Growth hormone-releasing hormone receptor | chr7 | GO:0042593 | Not Cancer Driver | No | 41 | 0.097 | 3 | 0 | 0.0 | 5 |
| GJB6_ENST00000644667 | GJB6 | O95452 | Gap junction beta-6 protein | chr13 | GO:0042593 | Not Cancer Driver | No | 42 | 0.161 | 12 | 4 | 0.333 | 4 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0042593 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0042593 | Not Cancer Driver | No | 77 | 0.138 | 73 | 11 | 0.151 | 24 |
| GPR1_ENST00000407325 | CMKLR2 | P46091 | Chemerin-like receptor 2 | chr2 | GO:0042593 | Not Cancer Driver | No | 50 | 0.141 | 0 | 0 | 0.0 | 0 |
| GPR21 | GPR21 | Q99679 | Probable G-protein coupled receptor 21 | chr9 | GO:0042593 | Not Cancer Driver | No | 39 | 0.112 | 2 | 0 | 0.0 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0042593 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GRIK5_ENST00000593562 | GRIK5 | Q16478 | Glutamate receptor ionotropic, kainate 5 | chr19 | GO:0042593 | Not Cancer Driver | No | 176 | 0.18 | 135 | 9 | 0.067 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0042593 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | GO:0042593 | Not Cancer Driver | No | 127 | 0.138 | 75 | 16 | 0.213 | 6 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0042593 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HK3 | HK3 | P52790 | Hexokinase-3 | chr5 | GO:0042593 | Not Cancer Driver | No | 164 | 0.178 | 71 | 17 | 0.239 | 0 |
| HKDC1 | HKDC1 | Q2TB90 | Hexokinase HKDC1 | chr10 | GO:0042593 | Not Cancer Driver | No | 146 | 0.159 | 33 | 3 | 0.091 | 0 |
| HNF1A_ENST00000257555 | HNF1A | P20823 | Hepatocyte nuclear factor 1-alpha | chr12 | GO:0042593 | Census, Compendium | Yes | 96 | 0.152 | 569 | 80 | 0.141 | 42 |
| HNF4A | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | GO:0042593 | Not Cancer Driver | No | 135 | 0.285 | 127 | 48 | 0.378 | 5 |
| ICAM1 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | GO:0042593 | Not Cancer Driver | No | 61 | 0.115 | 251 | 28 | 0.112 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0042593 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| IGFBP5 | IGFBP5 | P24593 | Insulin-like growth factor-binding protein 5 | chr2 | GO:0042593 | Not Cancer Driver | No | 27 | 0.099 | 112 | 17 | 0.152 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0042593 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0042593 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
| INS | INS | P01308 | Insulin | chr11 | GO:0042593 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0042593 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0042593 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0042593 | Not Cancer Driver | No | 69 | 0.052 | 1112 | 57 | 0.051 | 0 |
| KCNB1_ENST00000635465 | KCNB1 | Q14721 | Potassium voltage-gated channel subfamily B member 1 | chr20 | GO:0042593 | Not Cancer Driver | No | 192 | 0.224 | 417 | 100 | 0.24 | 6 |
| KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | GO:0042593 | Not Cancer Driver | No | 66 | 0.159 | 273 | 48 | 0.176 | 0 |
| KLF7 | KLF7 | O75840 | Krueppel-like factor 7 | chr2 | GO:0042593 | Not Cancer Driver | No | 46 | 0.152 | 72 | 7 | 0.097 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0042593 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LEPR | LEPR | P48357 | Leptin receptor | chr1 | GO:0042593 | Not Cancer Driver | No | 243 | 0.209 | 57 | 11 | 0.193 | 0 |
| LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0042593 | Not Cancer Driver | No | 37 | 0.177 | 86 | 12 | 0.14 | 0 |
| LRRC8A_ENST00000372599 | LRRC8A | Q8IWT6 | Volume-regulated anion channel subunit LRRC8A | chr9 | GO:0042593 | Not Cancer Driver | No | 105 | 0.13 | 32 | 3 | 0.094 | 0 |
| LRRC8D | LRRC8D | Q7L1W4 | Volume-regulated anion channel subunit LRRC8D | chr1 | GO:0042593 | Not Cancer Driver | No | 99 | 0.115 | 98 | 18 | 0.184 | 0 |
| MBD5 | MBD5 | Q9P267 | Methyl-CpG-binding domain protein 5 | chr2 | GO:0042593 | Not Cancer Driver | No | 254 | 0.17 | 1289 | 219 | 0.17 | 0 |
| MCU | MCU | Q8NE86 | Calcium uniporter protein, mitochondrial | chr10 | GO:0042593 | Not Cancer Driver | No | 41 | 0.117 | 13 | 0 | 0.0 | 0 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0042593 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MLXIPL | MLXIPL | Q9NP71 | Carbohydrate-responsive element-binding protein | chr7 | GO:0042593 | Not Cancer Driver | No | 106 | 0.124 | 554 | 66 | 0.119 | 0 |
| MTNR1B | MTNR1B | P49286 | Melatonin receptor type 1B | chr11 | GO:0042593 | Not Cancer Driver | No | 104 | 0.287 | 8 | 1 | 0.125 | 0 |
| NCOA5 | NCOA5 | Q9HCD5 | Nuclear receptor coactivator 5 | chr20 | GO:0042593 | Not Cancer Driver | No | 84 | 0.145 | 478 | 70 | 0.146 | 0 |
| NEUROD1 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0042593 | Not Cancer Driver | No | 84 | 0.236 | 202 | 52 | 0.257 | 2 |
| NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0042593 | Not Cancer Driver | No | 57 | 0.133 | 172 | 25 | 0.145 | 0 |
| NMB_ENST00000360476 | NMB | P08949 | Neuromedin-B | chr15 | GO:0042593 | Not Cancer Driver | No | 6 | 0.05 | 30 | 2 | 0.067 | 0 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:0042593 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| NPTX1 | NPTX1 | Q15818 | Neuronal pentraxin-1 | chr17 | GO:0042593 | Not Cancer Driver | No | 63 | 0.146 | 185 | 24 | 0.13 | 0 |
| NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0042593 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
| NR1H4 | NR1H4 | Q96RI1 | Bile acid receptor | chr12 | GO:0042593 | Not Cancer Driver | No | 111 | 0.228 | 78 | 18 | 0.231 | 0 |
| NUCKS1 | NUCKS1 | Q9H1E3 | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 | chr1 | GO:0042593 | Not Cancer Driver | No | 30 | 0.123 | 243 | 30 | 0.123 | 0 |
| OAS1_ENST00000202917 | OAS1 | P00973 | 2'-5'-oligoadenylate synthase 1 | chr12 | GO:0042593 | Not Cancer Driver | No | 67 | 0.168 | 71 | 12 | 0.169 | 0 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0042593 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0042593 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0042593 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
| PAX6_ENST00000241001 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0042593 | Not Cancer Driver | No | 72 | 0.171 | 337 | 56 | 0.166 | 38 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0042593 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0042593 | Not Cancer Driver | No | 91 | 0.142 | 139 | 13 | 0.094 | 0 |
| PDK2 | PDK2 | Q15119 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | chr17 | GO:0042593 | Not Cancer Driver | No | 45 | 0.111 | 35 | 4 | 0.114 | 0 |
| PDK3_ENST00000379162 | PDK3 | Q15120 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | chrX | GO:0042593 | Not Cancer Driver | No | 61 | 0.15 | 28 | 6 | 0.214 | 1 |
| PDK4 | PDK4 | Q16654 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | chr7 | GO:0042593 | Not Cancer Driver | No | 70 | 0.17 | 14 | 2 | 0.143 | 0 |
| PDX1 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:0042593 | Not Cancer Driver | No | 32 | 0.113 | 238 | 23 | 0.097 | 0 |
| PFKM_ENST00000550924 | PFKM | P08237 | ATP-dependent 6-phosphofructokinase, muscle type | chr12 | GO:0042593 | Not Cancer Driver | No | 80 | 0.103 | 70 | 8 | 0.114 | 9 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0042593 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0042593 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0042593 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
| PLSCR3 | PLSCR3 | Q9NRY6 | Phospholipid scramblase 3 | chr17 | GO:0042593 | Not Cancer Driver | No | 30 | 0.102 | 62 | 5 | 0.081 | 0 |
| POMC | POMC | P01189 | Pro-opiomelanocortin | chr2 | GO:0042593 | Not Cancer Driver | No | 50 | 0.187 | 198 | 38 | 0.192 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0042593 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PPARGC1A | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0042593 | Not Cancer Driver | No | 181 | 0.227 | 609 | 148 | 0.243 | 0 |
| PPP1R3G | PPP1R3G | B7ZBB8 | Protein phosphatase 1 regulatory subunit 3G | chr6 | GO:0042593 | Not Cancer Driver | No | 14 | 0.039 | 198 | 11 | 0.056 | 0 |
| PPP3CA | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0042593 | Compendium | Yes | 85 | 0.163 | 140 | 27 | 0.193 | 7 |
| PRCP_ENST00000313010 | PRCP | P42785 | Lysosomal Pro-X carboxypeptidase | chr11 | GO:0042593 | Not Cancer Driver | No | 58 | 0.117 | 0 | 0 | 0.0 | 0 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0042593 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0042593 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
| PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | GO:0042593 | Census | Yes | 53 | 0.151 | 24 | 0 | 0.0 | 2 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0042593 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0042593 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0042593 | Not Cancer Driver | No | 57 | 0.137 | 120 | 14 | 0.117 | 0 |
| PYGL | PYGL | P06737 | Glycogen phosphorylase, liver form | chr14 | GO:0042593 | Not Cancer Driver | No | 98 | 0.116 | 23 | 2 | 0.087 | 2 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0042593 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RBP4 | RBP4 | P02753 | Retinol-binding protein 4 | chr10 | GO:0042593 | Not Cancer Driver | No | 30 | 0.149 | 8 | 1 | 0.125 | 4 |
| RFX6 | RFX6 | Q8HWS3 | DNA-binding protein RFX6 | chr6 | GO:0042593 | Not Cancer Driver | No | 239 | 0.258 | 422 | 94 | 0.223 | 3 |
| RMI1 | RMI1 | Q9H9A7 | RecQ-mediated genome instability protein 1 | chr9 | GO:0042593 | Not Cancer Driver | No | 67 | 0.107 | 243 | 26 | 0.107 | 0 |
| RPH3AL | RPH3AL | Q9UNE2 | Rab effector Noc2 | chr17 | GO:0042593 | Not Cancer Driver | No | 40 | 0.127 | 162 | 20 | 0.123 | 0 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | GO:0042593 | Not Cancer Driver | No | 38 | 0.153 | 150 | 25 | 0.167 | 0 |
| SELENOT | SELENOT | P62341 | Thioredoxin reductase-like selenoprotein T | chr3 | GO:0042593 | Not Cancer Driver | No | 25 | 0.128 | 0 | 0 | 0.0 | 0 |
| SERPINF1 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0042593 | Not Cancer Driver | No | 51 | 0.122 | 57 | 5 | 0.088 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0042593 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SESN3 | SESN3 | P58005 | Sestrin-3 | chr11 | GO:0042593 | Not Cancer Driver | No | 84 | 0.171 | 44 | 4 | 0.091 | 0 |
| SIDT2_ENST00000620360 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | GO:0042593 | Not Cancer Driver | No | 113 | 0.136 | 23 | 6 | 0.261 | 0 |
| SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | GO:0042593 | Compendium | Yes | 172 | 0.135 | 617 | 73 | 0.118 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0042593 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0042593 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
| SLC16A1 | SLC16A1 | P53985 | Monocarboxylate transporter 1 | chr1 | GO:0042593 | Not Cancer Driver | No | 69 | 0.138 | 70 | 3 | 0.043 | 3 |
| SLC29A1_ENST00000371708 | SLC29A1 | Q99808 | Equilibrative nucleoside transporter 1 | chr6 | GO:0042593 | Not Cancer Driver | No | 51 | 0.112 | 27 | 4 | 0.148 | 0 |
| SLC2A4 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0042593 | Not Cancer Driver | No | 71 | 0.139 | 43 | 8 | 0.186 | 1 |
| SLC30A8 | SLC30A8 | Q8IWU4 | Zinc transporter 8 | chr8 | GO:0042593 | Not Cancer Driver | No | 115 | 0.312 | 25 | 9 | 0.36 | 0 |
| SLC39A14_ENST00000381237 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0042593 | Not Cancer Driver | No | 34 | 0.069 | 42 | 3 | 0.071 | 4 |
| SLC8B1 | SLC8B1 | Q6J4K2 | Mitochondrial sodium/calcium exchanger protein | chr12 | GO:0042593 | Not Cancer Driver | No | 70 | 0.12 | 0 | 0 | 0.0 | 0 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0042593 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SOX4 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | GO:0042593 | Not Cancer Driver | No | 28 | 0.059 | 400 | 24 | 0.06 | 4 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0042593 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0042593 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0042593 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| STXBP3 | STXBP3 | O00186 | Syntaxin-binding protein 3 | chr1 | GO:0042593 | Not Cancer Driver | No | 59 | 0.1 | 64 | 9 | 0.141 | 0 |
| SUCNR1 | SUCNR1 | Q9BXA5 | Succinate receptor 1 | chr3 | GO:0042593 | Not Cancer Driver | No | 51 | 0.153 | 0 | 0 | 0.0 | 0 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0042593 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0042593 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0042593 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| TRA2B | TRA2B | P62995 | Transformer-2 protein homolog beta | chr3 | GO:0042593 | Not Cancer Driver | No | 59 | 0.205 | 244 | 54 | 0.221 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0042593 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0042593 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| TWNK | TWNK | Q96RR1 | Twinkle mtDNA helicase | chr10 | GO:0042593 | Not Cancer Driver | No | 95 | 0.139 | 135 | 11 | 0.081 | 38 |
| UCP2 | UCP2 | P55851 | Mitochondrial uncoupling protein 2 | chr11 | GO:0042593 | Not Cancer Driver | No | 31 | 0.1 | 11 | 3 | 0.273 | 0 |
| UNC13B_ENST00000378495 | UNC13B | O14795 | Protein unc-13 homolog B | chr9 | GO:0042593 | Not Cancer Driver | No | 214 | 0.135 | 448 | 77 | 0.172 | 0 |
| USF1 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0042593 | Not Cancer Driver | No | 52 | 0.168 | 271 | 44 | 0.162 | 0 |
| VGF | VGF | O15240 | Neurosecretory protein VGF | chr7 | GO:0042593 | Not Cancer Driver | No | 48 | 0.078 | 593 | 47 | 0.079 | 0 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | GO:0042593 | Not Cancer Driver | No | 105 | 0.118 | 203 | 10 | 0.049 | 39 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0042593 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| ZBTB20 | ZBTB20 | Q9HC78 | Zinc finger and BTB domain-containing protein 20 | chr3 | GO:0042593 | Compendium | Yes | 151 | 0.204 | 433 | 80 | 0.185 | 4 |
| ZNF236_ENST00000253159 | ZNF236 | Q9UL36 | Zinc finger protein 236 | chr18 | GO:0042593 | Not Cancer Driver | No | 270 | 0.146 | 977 | 152 | 0.156 | 0 |