Total number of protein in "GO:0042531" GO term: 62
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARL2BP | ARL2BP | Q9Y2Y0 | ADP-ribosylation factor-like protein 2-binding protein | chr16 | GO:0042531 | Not Cancer Driver | No | 16 | 0.098 | 5 | 0 | 0.0 | 1 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0042531 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CLCF1 | CLCF1 | Q9UBD9 | Cardiotrophin-like cytokine factor 1 | chr11 | GO:0042531 | Not Cancer Driver | No | 22 | 0.098 | 42 | 4 | 0.095 | 1 |
| CNTF | CNTF | P26441 | Ciliary neurotrophic factor | chr11 | GO:0042531 | Not Cancer Driver | No | 41 | 0.205 | 34 | 5 | 0.147 | 0 |
| CRLF1 | CRLF1 | O75462 | Cytokine receptor-like factor 1 | chr19 | GO:0042531 | Not Cancer Driver | No | 51 | 0.121 | 101 | 7 | 0.069 | 14 |
| CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0042531 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
| CSF2 | CSF2 | P04141 | Granulocyte-macrophage colony-stimulating factor | chr5 | GO:0042531 | Not Cancer Driver | No | 11 | 0.076 | 34 | 3 | 0.088 | 0 |
| CSH1 | CSH1 | P0DML2 | Chorionic somatomammotropin hormone 1 | chr17 | GO:0042531 | Not Cancer Driver | No | 33 | 0.152 | 23 | 2 | 0.087 | 0 |
| CSH2 | CSH2 | P0DML3 | Chorionic somatomammotropin hormone 2 | chr17 | GO:0042531 | Not Cancer Driver | No | 53 | 0.244 | 23 | 3 | 0.13 | 0 |
| CSHL1 | CSHL1 | Q14406 | Chorionic somatomammotropin hormone-like 1 | chr17 | GO:0042531 | Not Cancer Driver | No | 63 | 0.284 | 18 | 5 | 0.278 | 0 |
| CTF1 | CTF1 | Q16619 | Cardiotrophin-1 | chr16 | GO:0042531 | Not Cancer Driver | No | 6 | 0.03 | 90 | 4 | 0.044 | 0 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0042531 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0042531 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
| FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0042531 | Census, Compendium | Yes | 173 | 0.215 | 241 | 26 | 0.108 | 37 |
| FLT3 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0042531 | Census, Compendium | Yes | 200 | 0.201 | 64 | 27 | 0.422 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0042531 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GH1 | GH1 | P01241 | Somatotropin | chr17 | GO:0042531 | Not Cancer Driver | No | 54 | 0.249 | 24 | 9 | 0.375 | 15 |
| GH2_ENST00000423893 | GH2 | P01242 | Growth hormone variant | chr17 | GO:0042531 | Not Cancer Driver | No | 55 | 0.253 | 12 | 9 | 0.75 | 0 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0042531 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| HCLS1 | HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | chr3 | GO:0042531 | Not Cancer Driver | No | 103 | 0.212 | 446 | 94 | 0.211 | 0 |
| HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0042531 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0042531 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HES5 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0042531 | Not Cancer Driver | No | 1 | 0.006 | 73 | 0 | 0.0 | 0 |
| HPX | HPX | P02790 | Hemopexin | chr11 | GO:0042531 | Not Cancer Driver | No | 60 | 0.13 | 53 | 8 | 0.151 | 0 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0042531 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| IFNA2 | IFNA2 | P01563 | Interferon alpha-2 | chr9 | GO:0042531 | Not Cancer Driver | No | 38 | 0.202 | 2 | 0 | 0.0 | 0 |
| IFNG | IFNG | P01579 | Interferon gamma | chr12 | GO:0042531 | Not Cancer Driver | No | 51 | 0.307 | 23 | 6 | 0.261 | 0 |
| IFNL1 | IFNL1 | Q8IU54 | Interferon lambda-1 | chr19 | GO:0042531 | Not Cancer Driver | No | 24 | 0.12 | 49 | 8 | 0.163 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0042531 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0042531 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
| IL13 | IL13 | P35225 | Interleukin-13 | chr5 | GO:0042531 | Not Cancer Driver | No | 20 | 0.137 | 0 | 0 | 0.0 | 0 |
| IL15_ENST00000320650 | IL15 | P40933 | Interleukin-15 | chr4 | GO:0042531 | Not Cancer Driver | No | 25 | 0.154 | 6 | 1 | 0.167 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0042531 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL2 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0042531 | Census | Yes | 24 | 0.157 | 6 | 1 | 0.167 | 0 |
| IL20_ENST00000367096 | IL20 | Q9NYY1 | Interleukin-20 | chr1 | GO:0042531 | Not Cancer Driver | No | 30 | 0.17 | 0 | 0 | 0.0 | 0 |
| IL21 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0042531 | Not Cancer Driver | No | 34 | 0.21 | 70 | 18 | 0.257 | 1 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0042531 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| IL23R | IL23R | Q5VWK5 | Interleukin-23 receptor | chr1 | GO:0042531 | Not Cancer Driver | No | 70 | 0.111 | 117 | 19 | 0.162 | 0 |
| IL24_ENST00000294984 | IL24 | Q13007 | Interleukin-24 | chr1 | GO:0042531 | Not Cancer Driver | No | 35 | 0.17 | 0 | 0 | 0.0 | 0 |
| IL3 | IL3 | P08700 | Interleukin-3 | chr5 | GO:0042531 | Not Cancer Driver | No | 25 | 0.164 | 22 | 3 | 0.136 | 0 |
| IL31RA_ENST00000297015 | IL31RA | Q8NI17 | Interleukin-31 receptor subunit alpha | chr5 | GO:0042531 | Not Cancer Driver | No | 117 | 0.16 | 163 | 30 | 0.184 | 1 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0042531 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0042531 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL6R | IL6R | P08887 | Interleukin-6 receptor subunit alpha | chr1 | GO:0042531 | Not Cancer Driver | No | 55 | 0.118 | 165 | 23 | 0.139 | 1 |
| IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0042531 | Census, Compendium | Yes | 102 | 0.111 | 315 | 40 | 0.127 | 2 |
| ISL1 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0042531 | Not Cancer Driver | No | 85 | 0.244 | 180 | 41 | 0.228 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0042531 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0042531 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0042531 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0042531 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0042531 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| OSBP | OSBP | P22059 | Oxysterol-binding protein 1 | chr11 | GO:0042531 | Not Cancer Driver | No | 83 | 0.103 | 386 | 39 | 0.101 | 0 |
| OSM | OSM | P13725 | Oncostatin-M | chr22 | GO:0042531 | Not Cancer Driver | No | 43 | 0.171 | 114 | 24 | 0.211 | 0 |
| PARP14 | PARP14 | Q460N5 | Protein mono-ADP-ribosyltransferase PARP14 | chr3 | GO:0042531 | Not Cancer Driver | No | 221 | 0.123 | 301 | 57 | 0.189 | 0 |
| PARP9 | PARP9 | Q8IXQ6 | Protein mono-ADP-ribosyltransferase PARP9 | chr3 | GO:0042531 | Not Cancer Driver | No | 110 | 0.129 | 45 | 3 | 0.067 | 0 |
| PIBF1 | PIBF1 | Q8WXW3 | Progesterone-induced-blocking factor 1 | chr13 | GO:0042531 | Not Cancer Driver | No | 83 | 0.11 | 419 | 45 | 0.107 | 2 |
| PTK6 | PTK6 | Q13882 | Protein-tyrosine kinase 6 | chr20 | GO:0042531 | Census | Yes | 42 | 0.093 | 12 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0042531 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF18_ENST00000379268 | TNFRSF18 | Q9Y5U5 | Tumor necrosis factor receptor superfamily member 18 | chr1 | GO:0042531 | Not Cancer Driver | No | 22 | 0.091 | 23 | 1 | 0.043 | 0 |
| TNFRSF1A | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0042531 | Not Cancer Driver | No | 58 | 0.127 | 111 | 15 | 0.135 | 12 |
| TSLP | TSLP | Q969D9 | Thymic stromal lymphopoietin | chr5 | GO:0042531 | Not Cancer Driver | No | 27 | 0.17 | 16 | 0 | 0.0 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0042531 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |