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Total number of protein in "GO:0042391" GO term:  405

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0042391 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCB5 ABCB5 Q2M3G0 ATP-binding cassette sub-family B member 5 chr7 GO:0042391 Not Cancer Driver No 370 0.294 106 35 0.33 0
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0042391 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0042391 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC092017.3 AC092017.3 A0A1W2PPV4 PAC domain-containing protein (Fragment) chr1 GO:0042391 Not Cancer Driver No 19 0.2 0 0 0.0 0
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0042391 Not Cancer Driver No 227 0.254 131 29 0.221 9
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0042391 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0042391 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0042391 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRB1 ADRB1 P08588 Beta-1 adrenergic receptor chr10 GO:0042391 Not Cancer Driver No 35 0.073 116 1 0.009 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0042391 Not Cancer Driver No 52 0.126 35 4 0.114 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0042391 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0042391 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0042391 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0042391 Census Yes 77 0.16 84 9 0.107 2
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0042391 Not Cancer Driver No 770 0.195 2844 566 0.199 4
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0042391 Not Cancer Driver No 860 0.196 3054 579 0.19 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0042391 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0042391 Not Cancer Driver No 26 0.138 0 0 0.0 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0042391 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0042391 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0042391 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0042391 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0042391 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0042391 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0042391 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0042391 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0042391 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 GO:0042391 Not Cancer Driver No 36 0.129 6 1 0.167 0
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0042391 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0042391 Not Cancer Driver No 8 0.075 85 7 0.082 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0042391 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0042391 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0042391 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0042391 Census Yes 30 0.156 39 2 0.051 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0042391 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0042391 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCO2 BCO2 Q9BYV7 Carotenoid-cleaving dioxygenase, mitochondrial chr11 GO:0042391 Not Cancer Driver No 79 0.136 14 1 0.071 0
BEST2_ENST00000042931 BEST2 Q8NFU1 Bestrophin-2 chr19 GO:0042391 Not Cancer Driver No 64 0.126 90 3 0.033 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0042391 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0042391 Not Cancer Driver No 65 0.11 456 42 0.092 5
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0042391 Not Cancer Driver No 7 0.033 0 0 0.0 0
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0042391 Not Cancer Driver No 59 0.164 65 15 0.231 1
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0042391 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0042391 Census, Compendium Yes 342 0.158 736 126 0.171 2
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0042391 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0042391 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CACNA1I CACNA1I Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I chr22 GO:0042391 Not Cancer Driver No 272 0.122 870 73 0.084 0
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0042391 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0042391 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0042391 Not Cancer Driver No 58 0.12 258 30 0.116 0
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0042391 Not Cancer Driver No 57 0.176 90 16 0.178 1
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0042391 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0042391 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0042391 Not Cancer Driver No 57 0.114 84 10 0.119 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0042391 Not Cancer Driver No 74 0.185 75 16 0.213 4
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0042391 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0042391 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0042391 Not Cancer Driver No 46 0.238 14 2 0.143 0
CCN6_ENST00000230529 CCN6 O95389 Cellular communication network factor 6 chr6 GO:0042391 Not Cancer Driver No 39 0.11 11 0 0.0 9
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0042391 Not Cancer Driver No 75 0.159 12 3 0.25 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0042391 Not Cancer Driver No 48 0.164 5 1 0.2 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0042391 Not Cancer Driver No 107 0.22 253 74 0.292 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0042391 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0042391 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHRFAM7A CHRFAM7A Q494W8 CHRNA7-FAM7A fusion protein chr15 GO:0042391 Not Cancer Driver No 40 0.097 18 0 0.0 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0042391 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0042391 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA1_ENST00000348749 CHRNA1 P02708 Acetylcholine receptor subunit alpha chr2 GO:0042391 Not Cancer Driver No 86 0.188 9 1 0.111 12
CHRNA2 CHRNA2 Q15822 Neuronal acetylcholine receptor subunit alpha-2 chr8 GO:0042391 Not Cancer Driver No 85 0.161 33 5 0.152 1
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0042391 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0042391 Not Cancer Driver No 144 0.23 186 33 0.177 2
CHRNA5 CHRNA5 P30532 Neuronal acetylcholine receptor subunit alpha-5 chr15 GO:0042391 Not Cancer Driver No 63 0.135 24 3 0.125 0
CHRNA6 CHRNA6 Q15825 Neuronal acetylcholine receptor subunit alpha-6 chr8 GO:0042391 Not Cancer Driver No 101 0.204 33 6 0.182 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0042391 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0042391 Not Cancer Driver No 76 0.159 23 6 0.261 0
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 GO:0042391 Not Cancer Driver No 62 0.124 45 9 0.2 3
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0042391 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHRNB3 CHRNB3 Q05901 Neuronal acetylcholine receptor subunit beta-3 chr8 GO:0042391 Not Cancer Driver No 125 0.273 4 1 0.25 0
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 GO:0042391 Not Cancer Driver No 98 0.197 30 6 0.2 0
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 GO:0042391 Not Cancer Driver No 110 0.213 71 19 0.268 7
CHRNE CHRNE Q04844 Acetylcholine receptor subunit epsilon chr17 GO:0042391 Not Cancer Driver No 52 0.105 37 3 0.081 13
CHRNG CHRNG P07510 Acetylcholine receptor subunit gamma chr2 GO:0042391 Not Cancer Driver No 78 0.151 8 1 0.125 4
CLCN1 CLCN1 P35523 Chloride channel protein 1 chr7 GO:0042391 Not Cancer Driver No 224 0.227 355 77 0.217 54
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0042391 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 GO:0042391 Not Cancer Driver No 32 0.133 27 5 0.185 0
CNGB1 CNGB1 Q14028 Cyclic nucleotide-gated cation channel beta-1 chr16 GO:0042391 Not Cancer Driver No 206 0.165 789 120 0.152 1
CNIH2 CNIH2 Q6PI25 Protein cornichon homolog 2 chr11 GO:0042391 Not Cancer Driver No 20 0.125 0 0 0.0 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0042391 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 GO:0042391 Not Cancer Driver No 57 0.158 21 4 0.19 0
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0042391 Not Cancer Driver No 173 0.125 141 15 0.106 6
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0042391 Census, Compendium Yes 63 0.099 606 62 0.102 0
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 GO:0042391 Not Cancer Driver No 269 0.301 186 50 0.269 1
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0042391 Not Cancer Driver No 34 0.093 0 0 0.0 31
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0042391 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0042391 Not Cancer Driver No 51 0.14 98 19 0.194 0
DCN DCN P07585 Decorin chr12 GO:0042391 Not Cancer Driver No 96 0.267 81 26 0.321 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0042391 Not Cancer Driver No 67 0.132 17 0 0.0 10
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0042391 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0042391 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMD DMD P11532 Dystrophin chrX GO:0042391 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0042391 Not Cancer Driver No 54 0.086 220 14 0.064 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0042391 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0042391 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0042391 Not Cancer Driver No 26 0.062 109 0 0.0 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 GO:0042391 Not Cancer Driver No 192 0.213 257 61 0.237 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 GO:0042391 Not Cancer Driver No 173 0.155 476 68 0.143 5
DSP DSP P15924 Desmoplakin chr6 GO:0042391 Not Cancer Driver No 483 0.168 1124 204 0.181 6
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0042391 Not Cancer Driver No 73 0.105 434 38 0.088 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0042391 Not Cancer Driver No 37 0.175 97 20 0.206 3
EHD3 EHD3 Q9NZN3 EH domain-containing protein 3 chr2 GO:0042391 Not Cancer Driver No 104 0.194 77 18 0.234 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0042391 Not Cancer Driver No 50 0.122 57 6 0.105 1
FAM19A4 TAFA4 Q96LR4 Chemokine-like protein TAFA-4 chr3 GO:0042391 Not Cancer Driver No 38 0.271 4 1 0.25 0
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 GO:0042391 Not Cancer Driver No 74 0.305 102 30 0.294 1
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0042391 Not Cancer Driver No 70 0.286 96 33 0.344 2
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX GO:0042391 Not Cancer Driver No 56 0.173 51 7 0.137 13
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0042391 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLNA FLNA P21333 Filamin-A chrX GO:0042391 Census Yes 416 0.157 1456 214 0.147 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0042391 Not Cancer Driver No 124 0.196 327 70 0.214 3
FXYD1_ENST00000455515 FXYD1 O00168 Phospholemman chr19 GO:0042391 Not Cancer Driver No 10 0.109 22 4 0.182 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0042391 Not Cancer Driver No 55 0.093 61 0 0.0 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0042391 Not Cancer Driver No 150 0.156 142 17 0.12 0
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0042391 Not Cancer Driver No 175 0.384 58 31 0.534 6
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0042391 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX GO:0042391 Not Cancer Driver No 136 0.276 47 10 0.213 0
GABRA4 GABRA4 P48169 Gamma-aminobutyric acid receptor subunit alpha-4 chr4 GO:0042391 Not Cancer Driver No 191 0.345 179 82 0.458 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0042391 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRA6 GABRA6 Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 chr5 GO:0042391 Not Cancer Driver No 186 0.411 7 2 0.286 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0042391 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0042391 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0042391 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRD GABRD O14764 Gamma-aminobutyric acid receptor subunit delta chr1 GO:0042391 Not Cancer Driver No 71 0.157 19 5 0.263 1
GABRE GABRE P78334 Gamma-aminobutyric acid receptor subunit epsilon chrX GO:0042391 Not Cancer Driver No 133 0.263 73 19 0.26 0
GABRG1 GABRG1 Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 chr4 GO:0042391 Not Cancer Driver No 216 0.465 7 3 0.429 0
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0042391 Not Cancer Driver No 188 0.403 19 13 0.684 11
GABRG3 GABRG3 Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 chr15 GO:0042391 Not Cancer Driver No 137 0.293 12 5 0.417 0
GABRP_ENST00000265294 GABRP O00591 Gamma-aminobutyric acid receptor subunit pi chr5 GO:0042391 Not Cancer Driver No 81 0.184 0 0 0.0 0
GABRQ GABRQ Q9UN88 Gamma-aminobutyric acid receptor subunit theta chrX GO:0042391 Not Cancer Driver No 158 0.25 175 58 0.331 0
GABRR1 GABRR1 P24046 Gamma-aminobutyric acid receptor subunit rho-1 chr6 GO:0042391 Not Cancer Driver No 93 0.194 99 26 0.263 0
GABRR2 GABRR2 P28476 Gamma-aminobutyric acid receptor subunit rho-2 chr6 GO:0042391 Not Cancer Driver No 64 0.138 8 0 0.0 0
GABRR3 GABRR3 A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 chr3 GO:0042391 Not Cancer Driver No 76 0.163 30 7 0.233 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0042391 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0042391 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0042391 Not Cancer Driver No 32 0.117 31 3 0.097 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0042391 Not Cancer Driver No 20 0.171 52 11 0.212 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0042391 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0042391 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJC1_ENST00000590758 GJC1 P36383 Gap junction gamma-1 protein chr17 GO:0042391 Not Cancer Driver No 63 0.159 150 30 0.2 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0042391 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0042391 Not Cancer Driver No 106 0.235 58 14 0.241 0
GLRA3 GLRA3 O75311 Glycine receptor subunit alpha-3 chr4 GO:0042391 Not Cancer Driver No 132 0.284 32 11 0.344 0
GLRB GLRB P48167 Glycine receptor subunit beta chr4 GO:0042391 Not Cancer Driver No 112 0.225 66 12 0.182 4
GLRX_ENST00000505427 GLRX P35754 Glutaredoxin-1 chr5 GO:0042391 Not Cancer Driver No 14 0.132 0 0 0.0 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0042391 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0042391 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0042391 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR88 GPR88 Q9GZN0 Probable G-protein coupled receptor 88 chr1 GO:0042391 Not Cancer Driver No 15 0.039 30 0 0.0 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0042391 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRIA3 GRIA3 P42263 Glutamate receptor 3 chrX GO:0042391 Not Cancer Driver No 209 0.234 56 15 0.268 4
GRID1 GRID1 Q9ULK0 Glutamate receptor ionotropic, delta-1 chr10 GO:0042391 Not Cancer Driver No 276 0.274 204 52 0.255 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0042391 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRIK1_ENST00000399907 GRIK1 P39086 Glutamate receptor ionotropic, kainate 1 chr21 GO:0042391 Not Cancer Driver No 196 0.214 50 5 0.1 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0042391 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIK3 GRIK3 Q13003 Glutamate receptor ionotropic, kainate 3 chr1 GO:0042391 Not Cancer Driver No 256 0.279 38 9 0.237 0
GRIK4_ENST00000438375 GRIK4 Q16099 Glutamate receptor ionotropic, kainate 4 chr11 GO:0042391 Not Cancer Driver No 179 0.187 74 8 0.108 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0042391 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0042391 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0042391 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0042391 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 GO:0042391 Not Cancer Driver No 111 0.09 276 6 0.022 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0042391 Not Cancer Driver No 125 0.094 467 15 0.032 1
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0042391 Not Cancer Driver No 308 0.276 179 22 0.123 0
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0042391 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0042391 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0042391 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0042391 Not Cancer Driver No 56 0.133 146 13 0.089 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0042391 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0042391 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0042391 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0042391 Not Cancer Driver No 187 0.155 631 58 0.092 3
HCRT HCRT O43612 Orexin chr17 GO:0042391 Not Cancer Driver No 3 0.023 45 0 0.0 1
HEBP2 HEBP2 Q9Y5Z4 Heme-binding protein 2 chr6 GO:0042391 Not Cancer Driver No 20 0.098 113 12 0.106 0
HSH2D HSH2D Q96JZ2 Hematopoietic SH2 domain-containing protein chr19 GO:0042391 Not Cancer Driver No 44 0.125 233 38 0.163 0
HTR3A_ENST00000504030 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 GO:0042391 Not Cancer Driver No 127 0.266 45 13 0.289 0
HTR3B HTR3B O95264 5-hydroxytryptamine receptor 3B chr11 GO:0042391 Not Cancer Driver No 91 0.206 8 0 0.0 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 GO:0042391 Not Cancer Driver No 82 0.183 35 7 0.2 0
HTR3D HTR3D Q70Z44 5-hydroxytryptamine receptor 3D chr3 GO:0042391 Not Cancer Driver No 61 0.134 59 16 0.271 0
HTR3E_ENST00000415389 HTR3E A5X5Y0 5-hydroxytryptamine receptor 3E chr3 GO:0042391 Not Cancer Driver No 87 0.191 56 18 0.321 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0042391 Not Cancer Driver No 12 0.092 7 0 0.0 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0042391 Not Cancer Driver No 98 0.227 159 28 0.176 0
INSYN1 INSYN1 Q2T9L4 Inhibitory synaptic factor 1 chr15 GO:0042391 Not Cancer Driver No 44 0.15 253 41 0.162 0
INSYN2 INSYN2A Q6ZSG2 Inhibitory synaptic factor 2A chr10 GO:0042391 Not Cancer Driver No 90 0.188 393 76 0.193 0
JUP JUP P14923 Junction plakoglobin chr17 GO:0042391 Not Cancer Driver No 112 0.15 241 37 0.154 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0042391 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0042391 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0042391 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNAB2_ENST00000378097 KCNAB2 Q13303 Voltage-gated potassium channel subunit beta-2 chr1 GO:0042391 Not Cancer Driver No 41 0.112 33 1 0.03 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0042391 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0042391 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0042391 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0042391 Not Cancer Driver No 220 0.349 195 62 0.318 0
KCND3 KCND3 Q9UK17 Potassium voltage-gated channel subfamily D member 3 chr1 GO:0042391 Not Cancer Driver No 172 0.263 202 44 0.218 5
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0042391 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0042391 Not Cancer Driver No 25 0.203 2 0 0.0 5
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 GO:0042391 Not Cancer Driver No 28 0.272 24 2 0.083 0
KCNE4 KCNE4 Q8WWG9 Potassium voltage-gated channel subfamily E member 4 chr2 GO:0042391 Not Cancer Driver No 26 0.118 94 18 0.191 0
KCNE5 KCNE5 Q9UJ90 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 chrX GO:0042391 Not Cancer Driver No 35 0.246 68 26 0.382 0
KCNH1 KCNH1 O95259 Potassium voltage-gated channel subfamily H member 1 chr1 GO:0042391 Not Cancer Driver No 247 0.25 248 70 0.282 10
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0042391 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNH3 KCNH3 Q9ULD8 Potassium voltage-gated channel subfamily H member 3 chr12 GO:0042391 Not Cancer Driver No 148 0.137 436 58 0.133 0
KCNH4 KCNH4 Q9UQ05 Potassium voltage-gated channel subfamily H member 4 chr17 GO:0042391 Not Cancer Driver No 168 0.165 402 51 0.127 0
KCNH5 KCNH5 Q8NCM2 Potassium voltage-gated channel subfamily H member 5 chr14 GO:0042391 Not Cancer Driver No 308 0.312 280 90 0.321 0
KCNH6 KCNH6 Q9H252 Potassium voltage-gated channel subfamily H member 6 chr17 GO:0042391 Not Cancer Driver No 202 0.203 284 67 0.236 0
KCNH7 KCNH7 Q9NS40 Potassium voltage-gated channel subfamily H member 7 chr2 GO:0042391 Not Cancer Driver No 324 0.271 508 138 0.272 0
KCNH8 KCNH8 Q96L42 Potassium voltage-gated channel subfamily H member 8 chr3 GO:0042391 Not Cancer Driver No 279 0.252 369 103 0.279 0
KCNIP2_ENST00000356640 KCNIP2 Q9NS61 Kv channel-interacting protein 2 chr10 GO:0042391 Not Cancer Driver No 34 0.126 89 16 0.18 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0042391 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0042391 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0042391 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNJ3 KCNJ3 P48549 G protein-activated inward rectifier potassium channel 1 chr2 GO:0042391 Not Cancer Driver No 189 0.377 162 64 0.395 0
KCNJ5_ENST00000533599 KCNJ5 P48544 G protein-activated inward rectifier potassium channel 4 chr11 GO:0042391 Census Yes 87 0.208 51 6 0.118 6
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0042391 Not Cancer Driver No 99 0.233 68 22 0.324 1
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 GO:0042391 Not Cancer Driver No 65 0.193 21 4 0.19 0
KCNK10_ENST00000340700 KCNK10 P57789 Potassium channel subfamily K member 10 chr14 GO:0042391 Not Cancer Driver No 138 0.257 174 47 0.27 0
KCNK12 KCNK12 Q9HB15 Potassium channel subfamily K member 12 chr2 GO:0042391 Not Cancer Driver No 6 0.014 29 0 0.0 0
KCNK13 KCNK13 Q9HB14 Potassium channel subfamily K member 13 chr14 GO:0042391 Not Cancer Driver No 99 0.243 32 8 0.25 0
KCNK15 KCNK15 Q9H427 Potassium channel subfamily K member 15 chr20 GO:0042391 Not Cancer Driver No 54 0.164 32 8 0.25 0
KCNK16_ENST00000373229 KCNK16 Q96T55 Potassium channel subfamily K member 16 chr6 GO:0042391 Not Cancer Driver No 63 0.204 14 1 0.071 0
KCNK17 KCNK17 Q96T54 Potassium channel subfamily K member 17 chr6 GO:0042391 Not Cancer Driver No 46 0.139 31 11 0.355 0
KCNK18 KCNK18 Q7Z418 Potassium channel subfamily K member 18 chr10 GO:0042391 Not Cancer Driver No 103 0.268 7 0 0.0 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0042391 Not Cancer Driver No 109 0.256 40 10 0.25 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0042391 Not Cancer Driver No 54 0.137 60 7 0.117 6
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0042391 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNK5 KCNK5 O95279 Potassium channel subfamily K member 5 chr6 GO:0042391 Not Cancer Driver No 94 0.188 206 36 0.175 0
KCNK6 KCNK6 Q9Y257 Potassium channel subfamily K member 6 chr19 GO:0042391 Not Cancer Driver No 39 0.125 22 4 0.182 0
KCNK7 KCNK7 Q9Y2U2 Potassium channel subfamily K member 7 chr11 GO:0042391 Not Cancer Driver No 31 0.101 6 1 0.167 0
KCNK9 KCNK9 Q9NPC2 Potassium channel subfamily K member 9 chr8 GO:0042391 Not Cancer Driver No 139 0.372 58 22 0.379 2
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 GO:0042391 Not Cancer Driver No 222 0.18 225 39 0.173 5
KCNMB2_ENST00000452583 KCNMB2 Q9Y691 Calcium-activated potassium channel subunit beta-2 chr3 GO:0042391 Not Cancer Driver No 61 0.26 0 0 0.0 0
KCNMB3 KCNMB3 Q9NPA1 Calcium-activated potassium channel subunit beta-3 chr3 GO:0042391 Not Cancer Driver No 27 0.097 22 2 0.091 0
KCNMB4 KCNMB4 Q86W47 Calcium-activated potassium channel subunit beta-4 chr12 GO:0042391 Not Cancer Driver No 41 0.195 0 0 0.0 0
KCNN2 KCNN2 Q9H2S1 Small conductance calcium-activated potassium channel protein 2 chr5 GO:0042391 Not Cancer Driver No 112 0.193 175 33 0.189 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0042391 Not Cancer Driver No 60 0.141 31 6 0.194 3
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0042391 Not Cancer Driver No 78 0.115 219 20 0.091 132
KCNQ3 KCNQ3 O43525 Potassium voltage-gated channel subfamily KQT member 3 chr8 GO:0042391 Not Cancer Driver No 249 0.286 411 109 0.265 3
KCTD7 KCTD7 Q96MP8 BTB/POZ domain-containing protein KCTD7 chr7 GO:0042391 Not Cancer Driver No 37 0.128 45 1 0.022 4
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0042391 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0042391 Census, Compendium Yes 122 0.127 586 67 0.114 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0042391 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0042391 Not Cancer Driver No 49 0.059 568 27 0.048 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0042391 Not Cancer Driver No 128 0.169 750 126 0.168 18
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0042391 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0042391 Not Cancer Driver No 92 0.195 408 81 0.199 0
MFN1 MFN1 Q8IWA4 Mitofusin-1 chr3 GO:0042391 Not Cancer Driver No 90 0.121 64 5 0.078 0
MLLT11 MLLT11 Q13015 Protein AF1q chr1 GO:0042391 Census Yes 15 0.167 18 5 0.278 0
MPP2_ENST00000461854 MPP2 Q14168 MAGUK p55 subfamily member 2 chr17 GO:0042391 Not Cancer Driver No 109 0.189 112 18 0.161 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0042391 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0042391 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0042391 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0042391 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0042391 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 GO:0042391 Not Cancer Driver No 275 0.138 1215 169 0.139 5
MYOC MYOC Q99972 Myocilin chr1 GO:0042391 Not Cancer Driver No 92 0.183 196 43 0.219 58
NALCN NALCN Q8IZF0 Sodium leak channel NALCN chr13 GO:0042391 Not Cancer Driver No 499 0.287 260 74 0.285 11
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 GO:0042391 Not Cancer Driver No 81 0.111 40 3 0.075 2
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0042391 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0042391 Not Cancer Driver No 126 0.129 463 60 0.13 4
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0042391 Not Cancer Driver No 186 0.349 103 33 0.32 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0042391 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0042391 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0042391 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0042391 Not Cancer Driver No 279 0.342 211 81 0.384 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0042391 Not Cancer Driver No 94 0.186 255 53 0.208 1
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0042391 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPFF NPFF O15130 Pro-FMRFamide-related neuropeptide FF chr12 GO:0042391 Not Cancer Driver No 16 0.142 64 7 0.109 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0042391 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0042391 Not Cancer Driver No 27 0.303 5 2 0.4 0
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0042391 Not Cancer Driver No 210 0.161 471 75 0.159 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0042391 Not Cancer Driver No 593 0.401 301 110 0.365 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0042391 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0042391 Not Cancer Driver No 85 0.203 23 1 0.043 0
NTSR2 NTSR2 O95665 Neurotensin receptor type 2 chr2 GO:0042391 Not Cancer Driver No 73 0.178 55 3 0.055 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 GO:0042391 Not Cancer Driver No 154 0.111 221 19 0.086 1
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0042391 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0042391 Not Cancer Driver No 107 0.268 58 27 0.466 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0042391 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0042391 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0042391 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0042391 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0042391 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0042391 Not Cancer Driver No 33 0.075 43 1 0.023 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0042391 Not Cancer Driver No 51 0.086 14 2 0.143 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0042391 Not Cancer Driver No 46 0.081 206 14 0.068 30
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0042391 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0042391 Not Cancer Driver No 119 0.117 320 34 0.106 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0042391 Not Cancer Driver No 70 0.111 266 31 0.117 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0042391 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0042391 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIEZO2 PIEZO2 Q9H5I5 Piezo-type mechanosensitive ion channel component 2 chr18 GO:0042391 Not Cancer Driver No 198 0.072 603 19 0.032 8
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0042391 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5KL1 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 GO:0042391 Not Cancer Driver No 28 0.071 74 6 0.081 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0042391 Not Cancer Driver No 176 0.2 434 98 0.226 8
PLN PLN P26678 Cardiac phospholamban chr6 GO:0042391 Not Cancer Driver No 10 0.192 0 0 0.0 3
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0042391 Not Cancer Driver No 2 0.037 23 1 0.043 0
POPDC2 POPDC2 Q9HBU9 Popeye domain-containing protein 2 chr3 GO:0042391 Not Cancer Driver No 49 0.135 91 10 0.11 0
POPDC3 POPDC3 Q9HBV1 Popeye domain-containing protein 3 chr6 GO:0042391 Not Cancer Driver No 68 0.234 0 0 0.0 3
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 GO:0042391 Not Cancer Driver No 49 0.147 71 9 0.127 9
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0042391 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0042391 Compendium Yes 85 0.163 140 27 0.193 7
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0042391 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0042391 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0042391 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0042391 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0042391 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0042391 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0042391 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0042391 Not Cancer Driver No 139 0.152 214 28 0.131 0
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 GO:0042391 Not Cancer Driver No 31 0.097 67 10 0.149 9
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0042391 Not Cancer Driver No 123 0.125 294 32 0.109 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0042391 Not Cancer Driver No 34 0.107 13 0 0.0 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0042391 Not Cancer Driver No 10 0.054 42 5 0.119 0
RELN RELN P78509 Reelin chr7 GO:0042391 Not Cancer Driver No 761 0.22 107 19 0.178 7
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0042391 Not Cancer Driver No 68 0.332 5 4 0.8 0
RGS7BP RGS7BP Q6MZT1 Regulator of G-protein signaling 7-binding protein chr5 GO:0042391 Not Cancer Driver No 49 0.191 166 31 0.187 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0042391 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIMS3 RIMS3 Q9UJD0 Regulating synaptic membrane exocytosis protein 3 chr1 GO:0042391 Not Cancer Driver No 61 0.198 162 39 0.241 0
RIMS4_ENST00000372851 RIMS4 Q9H426 Regulating synaptic membrane exocytosis protein 4 chr20 GO:0042391 Not Cancer Driver No 63 0.234 71 13 0.183 0
RNF122 RNF122 Q9H9V4 RING finger protein 122 chr8 GO:0042391 Not Cancer Driver No 24 0.155 0 0 0.0 0
RNF207 RNF207 Q6ZRF8 RING finger protein 207 chr1 GO:0042391 Not Cancer Driver No 48 0.076 198 13 0.066 0
RTL10_ENST00000407472 RTL10 Q7L3V2 Protein Bop chr22 GO:0042391 Not Cancer Driver No 52 0.143 196 31 0.158 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0042391 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0042391 Not Cancer Driver No 38 0.108 16 3 0.188 2
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0042391 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0042391 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0042391 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0042391 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0042391 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0042391 Not Cancer Driver No 46 0.214 52 7 0.135 2
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 GO:0042391 Not Cancer Driver No 415 0.207 432 83 0.192 6
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0042391 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 GO:0042391 Not Cancer Driver No 324 0.176 372 80 0.215 60
SCN4B SCN4B Q8IWT1 Sodium channel subunit beta-4 chr11 GO:0042391 Not Cancer Driver No 23 0.101 46 4 0.087 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0042391 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0042391 Not Cancer Driver No 395 0.235 171 43 0.251 0
SCN8A SCN8A Q9UQD0 Sodium channel protein type 8 subunit alpha chr12 GO:0042391 Not Cancer Driver No 290 0.146 460 75 0.163 28
SCN9A_ENST00000642356 SCN9A Q15858 Sodium channel protein type 9 subunit alpha chr2 GO:0042391 Not Cancer Driver No 461 0.232 490 126 0.257 21
SEZ6 SEZ6 Q53EL9 Seizure protein 6 homolog chr17 GO:0042391 Not Cancer Driver No 120 0.121 345 54 0.157 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0042391 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0042391 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0042391 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC25A36 SLC25A36 Q96CQ1 Solute carrier family 25 member 36 chr3 GO:0042391 Not Cancer Driver No 39 0.125 10 2 0.2 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0042391 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0042391 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0042391 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0042391 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC39A8 SLC39A8 Q9C0K1 Metal cation symporter ZIP8 chr4 GO:0042391 Not Cancer Driver No 45 0.098 22 2 0.091 5
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0042391 Not Cancer Driver No 159 0.182 69 10 0.145 42
SLC4A3_ENST00000317151 SLC4A3 P48751 Anion exchange protein 3 chr2 GO:0042391 Not Cancer Driver No 189 0.153 564 91 0.161 0
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0042391 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0042391 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0042391 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0042391 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0042391 Not Cancer Driver No 263 0.284 152 35 0.23 0
SLC8B1 SLC8B1 Q6J4K2 Mitochondrial sodium/calcium exchanger protein chr12 GO:0042391 Not Cancer Driver No 70 0.12 0 0 0.0 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0042391 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 GO:0042391 Not Cancer Driver No 77 0.093 464 38 0.082 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0042391 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0042391 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNTA1 SNTA1 Q13424 Alpha-1-syntrophin chr20 GO:0042391 Not Cancer Driver No 43 0.085 238 14 0.059 2
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0042391 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0042391 Not Cancer Driver No 32 0.144 25 5 0.2 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 GO:0042391 Not Cancer Driver No 112 0.168 396 68 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0042391 Census Yes 53 0.099 130 11 0.085 1
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0042391 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0042391 Not Cancer Driver No 121 0.122 659 83 0.126 2
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0042391 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0042391 Not Cancer Driver No 38 0.132 155 20 0.129 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0042391 Not Cancer Driver No 10 0.099 76 7 0.092 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0042391 Not Cancer Driver No 69 0.17 28 2 0.071 0
TBX18 TBX18 O95935 T-box transcription factor TBX18 chr6 GO:0042391 Not Cancer Driver No 156 0.257 356 94 0.264 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0042391 Not Cancer Driver No 155 0.299 351 113 0.322 5
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0042391 Census Yes 30 0.263 5 1 0.2 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0042391 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM161B_ENST00000296595 TMEM161B Q8NDZ6 Transmembrane protein 161B chr5 GO:0042391 Not Cancer Driver No 69 0.142 14 2 0.143 0
TMEM25_ENST00000313236 TMEM25 Q86YD3 Transmembrane protein 25 chr11 GO:0042391 Not Cancer Driver No 50 0.137 128 11 0.086 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0042391 Not Cancer Driver No 24 0.103 45 3 0.067 0
TRDN TRDN Q13061 Triadin chr6 GO:0042391 Not Cancer Driver No 129 0.177 639 102 0.16 1
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0042391 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0042391 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0042391 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0042391 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0042391 Not Cancer Driver No 5 0.03 1 0 0.0 0
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0042391 Not Cancer Driver No 10 0.091 31 3 0.097 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0042391 Not Cancer Driver No 20 0.087 102 8 0.078 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0042391 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0042391 Not Cancer Driver No 31 0.1 11 3 0.273 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0042391 Not Cancer Driver No 214 0.135 448 77 0.172 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0042391 Not Cancer Driver No 88 0.109 186 16 0.086 16
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0042391 Not Cancer Driver No 66 0.109 30 7 0.233 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0042391 Not Cancer Driver No 93 0.266 18 9 0.5 4
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0042391 Not Cancer Driver No 112 0.129 422 57 0.135 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0042391 Census Yes 32 0.125 41 3 0.073 0
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0042391 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 GO:0042391 Not Cancer Driver No 46 0.112 48 6 0.125 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0042391 Not Cancer Driver No 67 0.141 23 0 0.0 3