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Total number of protein in "GO:0042325" GO term:  664

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0042325 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0042325 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0042325 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0042325 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0042325 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0042325 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0042325 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0042325 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0042325 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0042325 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0042325 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0042325 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0042325 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0042325 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0042325 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0042325 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0042325 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0042325 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0042325 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0042325 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0042325 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0042325 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0042325 Not Cancer Driver No 36 0.118 87 9 0.103 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0042325 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 GO:0042325 Not Cancer Driver No 76 0.118 510 61 0.12 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0042325 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0042325 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0042325 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0042325 Not Cancer Driver No 7 0.046 31 0 0.0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0042325 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANG ANG P03950 Angiogenin chr14 GO:0042325 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0042325 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0042325 Not Cancer Driver No 104 0.207 150 32 0.213 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0042325 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APLNR APLNR P35414 Apelin receptor chr11 GO:0042325 Not Cancer Driver No 96 0.253 29 8 0.276 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0042325 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0042325 Census, Compendium Yes 84 0.139 181 32 0.177 0
AREG AREG P15514 Amphiregulin chr4 GO:0042325 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0042325 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0042325 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0042325 Census Yes 77 0.098 511 56 0.11 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0042325 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0042325 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0042325 Census, Compendium Yes 469 0.153 225 39 0.173 41
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0042325 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0042325 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZU1 AZU1 P20160 Azurocidin chr19 GO:0042325 Not Cancer Driver No 42 0.167 53 13 0.245 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0042325 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0042325 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0042325 Not Cancer Driver No 38 0.18 58 9 0.155 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0042325 Census Yes 96 0.124 384 49 0.128 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0042325 Census Yes 30 0.156 39 2 0.051 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0042325 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0042325 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0042325 Not Cancer Driver No 81 0.207 0 0 0.0 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0042325 Not Cancer Driver No 47 0.19 79 19 0.241 1
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0042325 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0042325 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0042325 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0042325 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0042325 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0042325 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0042325 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0042325 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0042325 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0042325 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPER BMPER Q8N8U9 BMP-binding endothelial regulator protein chr7 GO:0042325 Not Cancer Driver No 196 0.286 0 0 0.0 1
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0042325 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0042325 Compendium Yes 141 0.136 601 70 0.116 19
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0042325 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0042325 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BTC BTC P35070 Probetacellulin chr4 GO:0042325 Not Cancer Driver No 29 0.163 12 5 0.417 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0042325 Not Cancer Driver No 71 0.203 0 0 0.0 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0042325 Not Cancer Driver No 31 0.091 43 5 0.116 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:0042325 Not Cancer Driver No 48 0.124 94 9 0.096 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0042325 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0042325 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0042325 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0042325 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0042325 Not Cancer Driver No 40 0.108 31 1 0.032 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0042325 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0042325 Not Cancer Driver No 99 0.099 296 36 0.122 11
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0042325 Census Yes 32 0.116 62 5 0.081 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0042325 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0042325 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 GO:0042325 Census, Compendium Yes 83 0.127 502 70 0.139 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0042325 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0042325 Census Yes 160 0.163 562 104 0.185 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0042325 Census Yes 60 0.127 128 21 0.164 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0042325 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 GO:0042325 Not Cancer Driver No 122 0.273 61 22 0.361 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0042325 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0042325 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0042325 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0042325 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0042325 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0042325 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0042325 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0042325 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0042325 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0042325 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0042325 Not Cancer Driver No 31 0.086 100 8 0.08 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0042325 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0042325 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0042325 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0042325 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0042325 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0042325 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0042325 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0042325 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0042325 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0042325 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0042325 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0042325 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0042325 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0042325 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0042325 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0042325 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0042325 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0042325 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0042325 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:0042325 Census, Compendium Yes 23 0.137 49 6 0.122 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0042325 Not Cancer Driver No 17 0.102 44 3 0.068 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0042325 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0042325 Not Cancer Driver No 207 0.152 105 10 0.095 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0042325 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0042325 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 GO:0042325 Not Cancer Driver No 47 0.142 119 17 0.143 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0042325 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0042325 Not Cancer Driver No 86 0.17 11 1 0.091 0
CISH_ENST00000348721 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 GO:0042325 Not Cancer Driver No 33 0.128 97 8 0.082 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0042325 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0042325 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0042325 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0042325 Not Cancer Driver No 72 0.13 269 43 0.16 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0042325 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0042325 Compendium Yes 42 0.14 30 0 0.0 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0042325 Not Cancer Driver No 25 0.12 14 2 0.143 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0042325 Not Cancer Driver No 61 0.129 84 13 0.155 0
COX11 COX11 Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial chr17 GO:0042325 Not Cancer Driver No 21 0.076 51 4 0.078 0
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0042325 Not Cancer Driver No 15 0.125 78 5 0.064 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0042325 Census Yes 133 0.137 124 17 0.137 20
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0042325 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0042325 Not Cancer Driver No 20 0.093 19 0 0.0 4
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0042325 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0042325 Not Cancer Driver No 80 0.225 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0042325 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0042325 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0042325 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0042325 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0042325 Census, Compendium Yes 133 0.201 301 47 0.156 18
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0042325 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0042325 Not Cancer Driver No 87 0.094 410 42 0.102 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0042325 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0042325 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0042325 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0042325 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMD DMD P11532 Dystrophin chrX GO:0042325 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0042325 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0042325 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0042325 Not Cancer Driver No 60 0.119 131 17 0.13 0
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0042325 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0042325 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0042325 Not Cancer Driver No 52 0.103 286 27 0.094 19
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0042325 Not Cancer Driver No 49 0.14 210 25 0.119 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0042325 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0042325 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0042325 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0042325 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0042325 Not Cancer Driver No 84 0.457 0 0 0.0 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0042325 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0042325 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0042325 Not Cancer Driver No 54 0.257 78 21 0.269 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0042325 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0042325 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 GO:0042325 Not Cancer Driver No 74 0.16 121 17 0.14 3
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0042325 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0042325 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0042325 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0042325 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0042325 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0042325 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0042325 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0042325 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0042325 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:0042325 Not Cancer Driver No 30 0.122 17 3 0.176 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0042325 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENG ENG P17813 Endoglin chr9 GO:0042325 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0042325 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0042325 Not Cancer Driver No 41 0.096 6 1 0.167 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0042325 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPGN EPGN Q6UW88 Epigen chr4 GO:0042325 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0042325 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0042325 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0042325 Not Cancer Driver No 197 0.196 121 17 0.14 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0042325 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0042325 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0042325 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0042325 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0042325 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0042325 Not Cancer Driver No 55 0.119 297 37 0.125 0
F2 F2 P00734 Prothrombin chr11 GO:0042325 Not Cancer Driver No 115 0.185 97 25 0.258 10
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0042325 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0042325 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0042325 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0042325 Not Cancer Driver No 62 0.166 37 5 0.135 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0042325 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0042325 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0042325 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0042325 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0042325 Not Cancer Driver No 43 0.108 272 33 0.121 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0042325 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0042325 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0042325 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0042325 Census, Compendium Yes 200 0.201 64 27 0.422 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0042325 Not Cancer Driver No 124 0.196 327 70 0.214 3
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0042325 Not Cancer Driver No 143 0.123 384 44 0.115 0
FNIP2 FNIP2 Q9P278 Folliculin-interacting protein 2 chr4 GO:0042325 Not Cancer Driver No 119 0.107 555 71 0.128 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0042325 Compendium Yes 70 0.153 258 34 0.132 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0042325 Not Cancer Driver No 96 0.274 26 5 0.192 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0042325 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0042325 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0042325 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0042325 Not Cancer Driver No 72 0.104 146 3 0.021 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0042325 Not Cancer Driver No 10 0.061 39 5 0.128 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 GO:0042325 Not Cancer Driver No 71 0.174 111 19 0.171 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0042325 Not Cancer Driver No 82 0.121 42 6 0.143 0
GCG GCG P01275 Pro-glucagon chr2 GO:0042325 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCKR GCKR Q14397 Glucokinase regulatory protein chr2 GO:0042325 Not Cancer Driver No 98 0.157 85 27 0.318 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0042325 Not Cancer Driver No 88 0.189 73 14 0.192 107
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0042325 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0042325 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0042325 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0042325 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0042325 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0042325 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0042325 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0042325 Not Cancer Driver No 72 0.159 53 15 0.283 0
GH1 GH1 P01241 Somatotropin chr17 GO:0042325 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0042325 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0042325 Not Cancer Driver No 173 0.271 229 66 0.288 19
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0042325 Not Cancer Driver No 67 0.088 434 42 0.097 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0042325 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0042325 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0042325 Not Cancer Driver No 89 0.156 94 18 0.191 0
GPRC5A GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0042325 Not Cancer Driver No 43 0.12 19 4 0.211 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0042325 Not Cancer Driver No 82 0.203 75 19 0.253 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0042325 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0042325 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0042325 Not Cancer Driver No 32 0.152 0 0 0.0 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0042325 Not Cancer Driver No 46 0.124 125 19 0.152 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0042325 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0042325 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0042325 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0042325 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0042325 Not Cancer Driver No 178 0.147 409 59 0.144 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0042325 Not Cancer Driver No 173 0.125 974 135 0.139 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0042325 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 GO:0042325 Not Cancer Driver No 35 0.122 286 35 0.122 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0042325 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0042325 Compendium Yes 233 0.32 43 16 0.372 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0042325 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0042325 Census Yes 118 0.143 435 51 0.117 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0042325 Not Cancer Driver No 128 0.105 559 51 0.091 0
HRC HRC P23327 Sarcoplasmic reticulum histidine-rich calcium-binding protein chr19 GO:0042325 Not Cancer Driver No 110 0.157 612 98 0.16 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0042325 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0042325 Census, Compendium Yes 100 0.138 254 43 0.169 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0042325 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTT HTT P42858 Huntingtin chr4 GO:0042325 Not Cancer Driver No 336 0.107 666 69 0.104 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0042325 Not Cancer Driver No 52 0.11 8 1 0.125 0
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 GO:0042325 Not Cancer Driver No 146 0.108 364 39 0.107 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0042325 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0042325 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0042325 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0042325 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0042325 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0042325 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0042325 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0042325 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0042325 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0042325 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0042325 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0042325 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0042325 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0042325 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0042325 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0042325 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0042325 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0042325 Not Cancer Driver No 45 0.231 87 23 0.264 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0042325 Census, Compendium Yes 106 0.14 211 31 0.147 1
IL11 IL11 P20809 Interleukin-11 chr19 GO:0042325 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0042325 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0042325 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0042325 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL22RA2 IL22RA2 Q969J5 Interleukin-22 receptor subunit alpha-2 chr6 GO:0042325 Not Cancer Driver No 35 0.133 14 3 0.214 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0042325 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0042325 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0042325 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0042325 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0042325 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0042325 Not Cancer Driver No 55 0.118 165 23 0.139 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0042325 Not Cancer Driver No 49 0.153 84 12 0.143 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:0042325 Not Cancer Driver No 18 0.076 195 14 0.072 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0042325 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0042325 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0042325 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0042325 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0042325 Not Cancer Driver No 52 0.149 85 12 0.141 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0042325 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0042325 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0042325 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0042325 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0042325 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0042325 Not Cancer Driver No 128 0.117 52 3 0.058 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:0042325 Not Cancer Driver No 138 0.133 202 30 0.149 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0042325 Compendium Yes 71 0.1 337 39 0.116 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0042325 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0042325 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0042325 Not Cancer Driver No 26 0.13 58 11 0.19 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0042325 Census, Compendium Yes 136 0.12 59 5 0.085 5
JMJD8_ENST00000609261 JMJD8 Q96S16 JmjC domain-containing protein 8 chr16 GO:0042325 Not Cancer Driver No 11 0.042 22 0 0.0 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0042325 Census Yes 35 0.106 281 25 0.089 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0042325 Not Cancer Driver No 107 0.129 266 27 0.102 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0042325 Census, Compendium Yes 226 0.232 83 33 0.398 21
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0042325 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0042325 Census, Compendium Yes 178 0.164 687 116 0.169 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0042325 Not Cancer Driver No 66 0.216 191 39 0.204 0
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0042325 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0042325 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEP LEP P41159 Leptin chr7 GO:0042325 Not Cancer Driver No 29 0.174 0 0 0.0 2
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0042325 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0042325 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0042325 Not Cancer Driver No 162 0.362 277 115 0.415 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0042325 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0042325 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0042325 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0042325 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 GO:0042325 Not Cancer Driver No 289 0.143 261 33 0.126 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0042325 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0042325 Not Cancer Driver No 22 0.104 0 0 0.0 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0042325 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0042325 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0042325 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0042325 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0042325 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0042325 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0042325 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0042325 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0042325 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0042325 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0042325 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0042325 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0042325 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0042325 Not Cancer Driver No 70 0.134 173 25 0.145 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0042325 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0042325 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0042325 Not Cancer Driver No 47 0.145 5 2 0.4 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0042325 Not Cancer Driver No 101 0.14 128 22 0.172 0
MEN1 MEN1 O00255 Menin chr11 GO:0042325 Census, Compendium Yes 73 0.119 228 15 0.066 90
MIDN MIDN Q504T8 Midnolin chr19 GO:0042325 Not Cancer Driver No 43 0.092 446 43 0.096 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0042325 Not Cancer Driver No 4 0.035 0 0 0.0 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0042325 Not Cancer Driver No 106 0.124 554 66 0.119 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0042325 Not Cancer Driver No 23 0.074 64 2 0.031 0
MOB1B_ENST00000309395 MOB1B Q7L9L4 MOB kinase activator 1B chr4 GO:0042325 Not Cancer Driver No 17 0.079 7 0 0.0 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0042325 Not Cancer Driver No 84 0.119 292 35 0.12 1
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0042325 Not Cancer Driver No 110 0.155 168 19 0.113 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0042325 Not Cancer Driver No 68 0.181 64 11 0.172 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0042325 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTCP1_ENST00000362018 MTCP1 P56278 Protein p13 MTCP-1 chrX GO:0042325 Census, Compendium Yes 14 0.131 6 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0042325 Census, Compendium Yes 379 0.149 296 37 0.125 18
MVP MVP Q14764 Major vault protein chr16 GO:0042325 Not Cancer Driver No 141 0.158 285 31 0.109 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0042325 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0042325 Not Cancer Driver No 284 0.303 853 263 0.308 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0042325 Census Yes 67 0.128 395 51 0.129 0
NBN NBN O60934 Nibrin chr8 GO:0042325 Census Yes 90 0.119 417 54 0.129 1
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 GO:0042325 Not Cancer Driver No 113 0.099 72 8 0.111 3
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0042325 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0042325 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0042325 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0042325 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0042325 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0042325 Not Cancer Driver No 213 0.182 281 60 0.214 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0042325 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF2 NF2 P35240 Merlin chr22 GO:0042325 Census, Compendium Yes 69 0.116 252 26 0.103 16
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0042325 Not Cancer Driver No 66 0.274 93 25 0.269 1
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0042325 Not Cancer Driver No 310 0.292 116 43 0.371 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0042325 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0042325 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0042325 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0042325 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0042325 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPFFR2 NPFFR2 Q9Y5X5 Neuropeptide FF receptor 2 chr4 GO:0042325 Not Cancer Driver No 154 0.295 57 20 0.351 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0042325 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0042325 Not Cancer Driver No 32 0.212 71 14 0.197 1
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0042325 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 GO:0042325 Not Cancer Driver No 34 0.118 224 25 0.112 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0042325 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0042325 Not Cancer Driver No 227 0.315 425 134 0.315 0
NSD1 NSD1 Q96L73 Histone-lysine N-methyltransferase, H3 lysine-36 specific chr5 GO:0042325 Census, Compendium Yes 343 0.127 1864 206 0.111 14
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0042325 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0042325 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0042325 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0042325 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0042325 Not Cancer Driver No 10 0.122 82 10 0.122 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0042325 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0042325 Not Cancer Driver No 91 0.245 30 3 0.1 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0042325 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0042325 Not Cancer Driver No 43 0.171 114 24 0.211 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0042325 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0042325 Not Cancer Driver No 57 0.167 21 2 0.095 3
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0042325 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0042325 Compendium Yes 89 0.17 242 49 0.202 0
PAQR3 PAQR3 Q6TCH7 Progestin and adipoQ receptor family member 3 chr4 GO:0042325 Not Cancer Driver No 38 0.122 0 0 0.0 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0042325 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0042325 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0042325 Not Cancer Driver No 221 0.123 301 57 0.189 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0042325 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0042325 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0042325 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0042325 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0042325 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0042325 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0042325 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0042325 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0042325 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0042325 Not Cancer Driver No 33 0.059 121 12 0.099 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0042325 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0042325 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0042325 Not Cancer Driver No 20 0.143 0 0 0.0 0
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 GO:0042325 Not Cancer Driver No 20 0.079 70 5 0.071 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0042325 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0042325 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0042325 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0042325 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0042325 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0042325 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0042325 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0042325 Not Cancer Driver No 51 0.111 149 20 0.134 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0042325 Not Cancer Driver No 193 0.142 315 45 0.143 0
PIK3R5 PIK3R5 Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 chr17 GO:0042325 Not Cancer Driver No 143 0.163 316 55 0.174 1
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0042325 Not Cancer Driver No 100 0.133 156 26 0.167 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0042325 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0042325 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0042325 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0042325 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0042325 Not Cancer Driver No 62 0.147 111 23 0.207 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0042325 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0042325 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0042325 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0042325 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0042325 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0042325 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCL1 PLCL1 Q15111 Inactive phospholipase C-like protein 1 chr2 GO:0042325 Not Cancer Driver No 258 0.236 205 33 0.161 0
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0042325 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0042325 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0042325 Not Cancer Driver No 87 0.144 119 13 0.109 0
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 GO:0042325 Not Cancer Driver No 45 0.157 196 34 0.173 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0042325 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0042325 Census Yes 72 0.143 44 4 0.091 3
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0042325 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0042325 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 GO:0042325 Not Cancer Driver No 62 0.126 237 34 0.143 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0042325 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R14A PPP1R14A Q96A00 Protein phosphatase 1 regulatory subunit 14A chr19 GO:0042325 Not Cancer Driver No 14 0.095 113 10 0.088 0
PPP1R14B PPP1R14B Q96C90 Protein phosphatase 1 regulatory subunit 14B chr11 GO:0042325 Not Cancer Driver No 10 0.068 94 8 0.085 0
PPP1R14C PPP1R14C Q8TAE6 Protein phosphatase 1 regulatory subunit 14C chr6 GO:0042325 Not Cancer Driver No 14 0.085 125 9 0.072 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0042325 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0042325 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0042325 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0042325 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0042325 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0042325 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0042325 Not Cancer Driver No 79 0.159 119 9 0.076 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 GO:0042325 Not Cancer Driver No 41 0.134 0 0 0.0 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 GO:0042325 Not Cancer Driver No 32 0.077 314 26 0.083 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0042325 Not Cancer Driver No 100 0.118 240 33 0.138 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0042325 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0042325 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0042325 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0042325 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0042325 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0042325 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0042325 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0042325 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0042325 Compendium Yes 79 0.117 43 9 0.209 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0042325 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0042325 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0042325 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0042325 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRLR PRLR P16471 Prolactin receptor chr5 GO:0042325 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0042325 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0042325 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0042325 Not Cancer Driver No 42 0.094 235 24 0.102 0
PRXL2C PRXL2C Q7RTV5 Peroxiredoxin-like 2C chr9 GO:0042325 Not Cancer Driver No 10 0.044 26 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0042325 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0042325 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0042325 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0042325 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0042325 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0042325 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0042325 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0042325 Census Yes 42 0.093 12 0 0.0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0042325 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0042325 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0042325 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0042325 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0042325 Census, Compendium Yes 315 0.241 462 107 0.232 0
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0042325 Not Cancer Driver No 51 0.102 186 22 0.118 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0042325 Not Cancer Driver No 16 0.082 39 4 0.103 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0042325 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD17 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 GO:0042325 Census Yes 78 0.115 207 19 0.092 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0042325 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0042325 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0042325 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0042325 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0042325 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0042325 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0042325 Not Cancer Driver No 32 0.175 8 2 0.25 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0042325 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0042325 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0042325 Not Cancer Driver No 73 0.076 505 48 0.095 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0042325 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0042325 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 GO:0042325 Not Cancer Driver No 140 0.131 335 41 0.122 0
RBL2 RBL2 Q08999 Retinoblastoma-like protein 2 chr16 GO:0042325 Not Cancer Driver No 116 0.102 504 56 0.111 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0042325 Not Cancer Driver No 23 0.117 87 11 0.126 0
RELN RELN P78509 Reelin chr7 GO:0042325 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0042325 Census, Compendium Yes 208 0.187 105 12 0.114 139
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0042325 Not Cancer Driver No 9 0.066 81 7 0.086 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 GO:0042325 Not Cancer Driver No 212 0.124 366 50 0.137 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0042325 Not Cancer Driver No 63 0.117 143 20 0.14 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0042325 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0042325 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0042325 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0042325 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0042325 Not Cancer Driver No 176 0.132 241 21 0.087 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0042325 Not Cancer Driver No 147 0.151 403 57 0.141 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0042325 Not Cancer Driver No 38 0.108 16 3 0.188 2
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0042325 Not Cancer Driver No 112 0.3 291 85 0.292 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0042325 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0042325 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0042325 Not Cancer Driver No 117 0.136 132 15 0.114 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0042325 Not Cancer Driver No 142 0.364 47 28 0.596 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0042325 Not Cancer Driver No 74 0.154 147 26 0.177 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0042325 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0042325 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0042325 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0042325 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0042325 Not Cancer Driver No 110 0.128 440 72 0.164 0
SH3BP5 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0042325 Not Cancer Driver No 46 0.101 378 35 0.093 0
SH3BP5L SH3BP5L Q7L8J4 SH3 domain-binding protein 5-like chr1 GO:0042325 Not Cancer Driver No 62 0.158 376 57 0.152 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0042325 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0042325 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0042325 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0042325 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0042325 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0042325 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0042325 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC2A6 SLC2A6 Q9UGQ3 Solute carrier family 2, facilitated glucose transporter member 6 chr9 GO:0042325 Not Cancer Driver No 65 0.128 31 2 0.065 0
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0042325 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0042325 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0042325 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0042325 Not Cancer Driver No 263 0.284 152 35 0.23 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0042325 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0042325 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0042325 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0042325 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0042325 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX25 SNX25 Q9H3E2 Sorting nexin-25 chr4 GO:0042325 Not Cancer Driver No 101 0.12 114 10 0.088 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0042325 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0042325 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0042325 Not Cancer Driver No 32 0.162 61 2 0.033 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0042325 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS4_ENST00000555846 SOCS4 Q8WXH5 Suppressor of cytokine signaling 4 chr14 GO:0042325 Not Cancer Driver No 43 0.098 136 13 0.096 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0042325 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 GO:0042325 Not Cancer Driver No 81 0.151 299 48 0.161 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0042325 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0042325 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0042325 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0042325 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0042325 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0042325 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0042325 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0042325 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0042325 Not Cancer Driver No 312 0.122 866 103 0.119 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0042325 Census Yes 53 0.099 130 11 0.085 1
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0042325 Not Cancer Driver No 86 0.185 64 13 0.203 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0042325 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0042325 Census, Compendium Yes 110 0.143 152 15 0.099 19
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0042325 Not Cancer Driver No 70 0.144 231 30 0.13 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0042325 Not Cancer Driver No 121 0.122 659 83 0.126 2
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0042325 Census Yes 96 0.151 131 27 0.206 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0042325 Census Yes 54 0.163 305 53 0.174 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0042325 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0042325 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0042325 Not Cancer Driver No 101 0.139 42 5 0.119 12
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0042325 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0042325 Census Yes 30 0.263 5 1 0.2 0
TCL1B TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 GO:0042325 Not Cancer Driver No 38 0.297 11 1 0.091 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0042325 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0042325 Not Cancer Driver No 728 0.267 482 164 0.34 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0042325 Not Cancer Driver No 28 0.07 310 16 0.052 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0042325 Not Cancer Driver No 63 0.101 339 35 0.103 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0042325 Compendium Yes 61 0.18 285 52 0.182 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0042325 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0042325 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0042325 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0042325 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0042325 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0042325 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0042325 Census, Compendium Yes 106 0.187 60 16 0.267 25
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0042325 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0042325 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0042325 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0042325 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0042325 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0042325 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0042325 Not Cancer Driver No 24 0.119 25 4 0.16 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0042325 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0042325 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFAIP8L3 TNFAIP8L3 Q5GJ75 Tumor necrosis factor alpha-induced protein 8-like protein 3 chr15 GO:0042325 Not Cancer Driver No 40 0.137 111 12 0.108 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0042325 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0042325 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0042325 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0042325 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0042325 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TNXB_ENST00000375244 TNXB P22105 Tenascin-X chr6 GO:0042325 Not Cancer Driver No 666 0.157 2794 498 0.178 5
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0042325 Not Cancer Driver No 51 0.107 268 29 0.108 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0042325 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0042325 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0042325 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0042325 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0042325 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0042325 Not Cancer Driver No 255 0.262 148 32 0.216 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0042325 Not Cancer Driver No 46 0.118 159 23 0.145 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0042325 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTC36 TTC36 A6NLP5 Tetratricopeptide repeat protein 36 chr11 GO:0042325 Not Cancer Driver No 13 0.069 98 12 0.122 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0042325 Not Cancer Driver No 136 0.159 352 46 0.131 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0042325 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0042325 Not Cancer Driver No 23 0.114 132 11 0.083 7
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0042325 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXN TXN P10599 Thioredoxin chr9 GO:0042325 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0042325 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0042325 Not Cancer Driver No 24 0.12 33 3 0.091 0
UCN UCN P55089 Urocortin chr2 GO:0042325 Not Cancer Driver No 7 0.056 61 4 0.066 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0042325 Not Cancer Driver No 20 0.083 89 4 0.045 1
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0042325 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0042325 Not Cancer Driver No 153 0.181 102 18 0.176 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0042325 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0042325 Not Cancer Driver No 128 0.305 37 12 0.324 0
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 GO:0042325 Not Cancer Driver No 16 0.091 10 0 0.0 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0042325 Not Cancer Driver No 6 0.013 336 6 0.018 0
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 GO:0042325 Not Cancer Driver No 164 0.084 721 51 0.071 1
WDR91 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 GO:0042325 Not Cancer Driver No 99 0.133 206 38 0.184 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0042325 Not Cancer Driver No 104 0.183 345 65 0.188 1
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0042325 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0042325 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0042325 Not Cancer Driver No 66 0.174 0 0 0.0 2
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0042325 Compendium Yes 151 0.204 433 80 0.185 4
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0042325 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0042325 Not Cancer Driver No 85 0.149 383 55 0.144 0
ZFYVE28 ZFYVE28 Q9HCC9 Lateral signaling target protein 2 homolog chr4 GO:0042325 Not Cancer Driver No 132 0.149 420 67 0.16 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 GO:0042325 Not Cancer Driver No 75 0.141 346 49 0.142 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0042325 Not Cancer Driver No 114 0.201 91 19 0.209 0