Total number of protein in "GO:0042177" GO term: 77
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRB1_ENST00000323289 | ADGRB1 | O14514 | Adhesion G protein-coupled receptor B1 | chr8 | GO:0042177 | Compendium | Yes | 213 | 0.134 | 485 | 47 | 0.097 | 0 |
| AGAP2 | AGAP2 | Q99490 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 | chr12 | GO:0042177 | Not Cancer Driver | No | 133 | 0.112 | 754 | 81 | 0.107 | 0 |
| ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | GO:0042177 | Not Cancer Driver | No | 49 | 0.145 | 20 | 4 | 0.2 | 0 |
| AQP11 | AQP11 | Q8NBQ7 | Aquaporin-11 | chr11 | GO:0042177 | Not Cancer Driver | No | 23 | 0.085 | 0 | 0 | 0.0 | 0 |
| ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:0042177 | Not Cancer Driver | No | 152 | 0.129 | 121 | 10 | 0.083 | 9 |
| AZIN1 | AZIN1 | O14977 | Antizyme inhibitor 1 | chr8 | GO:0042177 | Not Cancer Driver | No | 39 | 0.087 | 10 | 2 | 0.2 | 0 |
| AZIN2_ENST00000294517 | AZIN2 | Q96A70 | Antizyme inhibitor 2 | chr1 | GO:0042177 | Not Cancer Driver | No | 51 | 0.111 | 14 | 0 | 0.0 | 0 |
| BANP_ENST00000286122 | BANP | Q8N9N5 | Protein BANP | chr16 | GO:0042177 | Not Cancer Driver | No | 74 | 0.143 | 311 | 43 | 0.138 | 0 |
| CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0042177 | Not Cancer Driver | No | 71 | 0.182 | 75 | 8 | 0.107 | 4 |
| CSNK2A2 | CSNK2A2 | P19784 | Casein kinase II subunit alpha' | chr16 | GO:0042177 | Not Cancer Driver | No | 43 | 0.123 | 13 | 1 | 0.077 | 0 |
| CST3_ENST00000376925 | CST3 | P01034 | Cystatin-C | chr20 | GO:0042177 | Not Cancer Driver | No | 17 | 0.116 | 31 | 1 | 0.032 | 2 |
| CTSA_ENST00000372459 | CTSA | P10619 | Lysosomal protective protein | chr20 | GO:0042177 | Not Cancer Driver | No | 59 | 0.123 | 14 | 1 | 0.071 | 12 |
| CYP51A1 | CYP51A1 | Q16850 | Lanosterol 14-alpha demethylase | chr7 | GO:0042177 | Not Cancer Driver | No | 49 | 0.096 | 7 | 2 | 0.286 | 0 |
| DEDD_ENST00000545495 | DEDD | O75618 | Death effector domain-containing protein | chr1 | GO:0042177 | Not Cancer Driver | No | 36 | 0.113 | 90 | 7 | 0.078 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0042177 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0042177 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FMN2 | FMN2 | Q9NZ56 | Formin-2 | chr1 | GO:0042177 | Not Cancer Driver | No | 614 | 0.357 | 1322 | 475 | 0.359 | 0 |
| FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | GO:0042177 | Not Cancer Driver | No | 93 | 0.117 | 283 | 35 | 0.124 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0042177 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GRIN2A_ENST00000330684 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0042177 | Census, Compendium | Yes | 528 | 0.361 | 506 | 207 | 0.409 | 31 |
| GRIN2C | GRIN2C | Q14957 | Glutamate receptor ionotropic, NMDA 2C | chr17 | GO:0042177 | Not Cancer Driver | No | 111 | 0.09 | 276 | 6 | 0.022 | 0 |
| HFE | HFE | Q30201 | Hereditary hemochromatosis protein | chr6 | GO:0042177 | Not Cancer Driver | No | 55 | 0.158 | 27 | 2 | 0.074 | 11 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0042177 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| HMGCR_ENST00000511206 | HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | chr5 | GO:0042177 | Not Cancer Driver | No | 84 | 0.095 | 112 | 12 | 0.107 | 0 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0042177 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| INS | INS | P01308 | Insulin | chr11 | GO:0042177 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| IRAK3 | IRAK3 | Q9Y616 | Interleukin-1 receptor-associated kinase 3 | chr12 | GO:0042177 | Not Cancer Driver | No | 103 | 0.173 | 79 | 14 | 0.177 | 0 |
| LAPTM4B_ENST00000619747 | LAPTM4B | Q86VI4 | Lysosomal-associated transmembrane protein 4B | chr8 | GO:0042177 | Not Cancer Driver | No | 24 | 0.076 | 73 | 5 | 0.068 | 0 |
| LRIG2 | LRIG2 | O94898 | Leucine-rich repeats and immunoglobulin-like domains protein 2 | chr1 | GO:0042177 | Not Cancer Driver | No | 131 | 0.123 | 231 | 30 | 0.13 | 0 |
| MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | GO:0042177 | Not Cancer Driver | No | 26 | 0.127 | 12 | 1 | 0.083 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0042177 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MDM4 | MDM4 | O15151 | Protein Mdm4 | chr1 | GO:0042177 | Census, Compendium | Yes | 57 | 0.116 | 202 | 26 | 0.129 | 1 |
| MGAT3 | MGAT3 | Q09327 | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | chr22 | GO:0042177 | Not Cancer Driver | No | 105 | 0.197 | 130 | 27 | 0.208 | 0 |
| MYCBP2_ENST00000357337 | MYCBP2 | O75592 | E3 ubiquitin-protein ligase MYCBP2 | chr13 | GO:0042177 | Not Cancer Driver | No | 608 | 0.13 | 1398 | 189 | 0.135 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0042177 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0042177 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| PDCL3 | PDCL3 | Q9H2J4 | Phosducin-like protein 3 | chr2 | GO:0042177 | Not Cancer Driver | No | 48 | 0.201 | 73 | 13 | 0.178 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0042177 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0042177 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0042177 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PRKCG | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:0042177 | Not Cancer Driver | No | 172 | 0.247 | 151 | 43 | 0.285 | 5 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0042177 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | GO:0042177 | Not Cancer Driver | No | 139 | 0.152 | 214 | 28 | 0.131 | 0 |
| QRICH2 | QRICH2 | Q9H0J4 | Glutamine-rich protein 2 | chr17 | GO:0042177 | Not Cancer Driver | No | 204 | 0.123 | 1369 | 171 | 0.125 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0042177 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RILP | RILP | Q96NA2 | Rab-interacting lysosomal protein | chr17 | GO:0042177 | Not Cancer Driver | No | 30 | 0.075 | 333 | 21 | 0.063 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0042177 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | GO:0042177 | Not Cancer Driver | No | 27 | 0.152 | 12 | 1 | 0.083 | 1 |
| RPL23_ENST00000394332 | RPL23 | P62829 | 60S ribosomal protein L23 | chr17 | GO:0042177 | Not Cancer Driver | No | 14 | 0.1 | 29 | 4 | 0.138 | 0 |
| RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | GO:0042177 | Census | Yes | 57 | 0.192 | 96 | 17 | 0.177 | 2 |
| RPS7_ENST00000645674 | RPS7 | P62081 | 40S ribosomal protein S7 | chr2 | GO:0042177 | Not Cancer Driver | No | 29 | 0.149 | 39 | 7 | 0.179 | 0 |
| SERPINB12_ENST00000269491 | SERPINB12 | Q96P63 | Serpin B12 | chr18 | GO:0042177 | Not Cancer Driver | No | 82 | 0.202 | 21 | 6 | 0.286 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0042177 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SF3B3 | SF3B3 | Q15393 | Splicing factor 3B subunit 3 | chr16 | GO:0042177 | Not Cancer Driver | No | 154 | 0.127 | 145 | 19 | 0.131 | 0 |
| SGTA | SGTA | O43765 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha | chr19 | GO:0042177 | Not Cancer Driver | No | 38 | 0.121 | 159 | 23 | 0.145 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0042177 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0042177 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0042177 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0042177 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | GO:0042177 | Not Cancer Driver | No | 38 | 0.087 | 416 | 37 | 0.089 | 0 |
| SNX12 | SNX12 | Q9UMY4 | Sorting nexin-12 | chrX | GO:0042177 | Not Cancer Driver | No | 22 | 0.136 | 28 | 4 | 0.143 | 0 |
| SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | GO:0042177 | Not Cancer Driver | No | 21 | 0.13 | 37 | 4 | 0.108 | 0 |
| STYX | STYX | Q8WUJ0 | Serine/threonine/tyrosine-interacting protein | chr14 | GO:0042177 | Not Cancer Driver | No | 20 | 0.09 | 30 | 2 | 0.067 | 0 |
| SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0042177 | Census | Yes | 55 | 0.114 | 199 | 19 | 0.095 | 2 |
| SVIP | SVIP | Q8NHG7 | Small VCP/p97-interacting protein | chr11 | GO:0042177 | Not Cancer Driver | No | 16 | 0.208 | 77 | 16 | 0.208 | 0 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0042177 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0042177 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |
| TIMP2 | TIMP2 | P16035 | Metalloproteinase inhibitor 2 | chr17 | GO:0042177 | Not Cancer Driver | No | 31 | 0.141 | 6 | 2 | 0.333 | 0 |
| TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | GO:0042177 | Not Cancer Driver | No | 43 | 0.204 | 3 | 1 | 0.333 | 5 |
| TIMP4 | TIMP4 | Q99727 | Metalloproteinase inhibitor 4 | chr3 | GO:0042177 | Not Cancer Driver | No | 30 | 0.134 | 8 | 2 | 0.25 | 0 |
| TRIM39 | TRIM39 | Q9HCM9 | E3 ubiquitin-protein ligase TRIM39 | chr6 | GO:0042177 | Not Cancer Driver | No | 74 | 0.143 | 62 | 8 | 0.129 | 0 |
| TRIM40_ENST00000376724 | TRIM40 | Q6P9F5 | E3 ubiquitin ligase TRIM40 | chr6 | GO:0042177 | Not Cancer Driver | No | 44 | 0.171 | 84 | 12 | 0.143 | 0 |
| UBXN1_ENST00000301935 | UBXN1 | Q04323 | UBX domain-containing protein 1 | chr11 | GO:0042177 | Not Cancer Driver | No | 35 | 0.118 | 271 | 33 | 0.122 | 0 |
| USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | GO:0042177 | Not Cancer Driver | No | 59 | 0.119 | 86 | 6 | 0.07 | 0 |
| USP25_ENST00000285679 | USP25 | Q9UHP3 | Ubiquitin carboxyl-terminal hydrolase 25 | chr21 | GO:0042177 | Not Cancer Driver | No | 135 | 0.128 | 354 | 55 | 0.155 | 0 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0042177 | Not Cancer Driver | No | 68 | 0.085 | 99 | 9 | 0.091 | 1 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0042177 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |