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Total number of protein in "GO:0042176" GO term:  115

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0042176 Not Cancer Driver No 240 0.099 497 44 0.089 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0042176 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0042176 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0042176 Not Cancer Driver No 67 0.144 161 10 0.062 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0042176 Not Cancer Driver No 49 0.145 20 4 0.2 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0042176 Not Cancer Driver No 25 0.079 124 6 0.048 12
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0042176 Not Cancer Driver No 23 0.085 0 0 0.0 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0042176 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0042176 Not Cancer Driver No 46 0.127 181 24 0.133 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0042176 Not Cancer Driver No 98 0.087 861 79 0.092 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0042176 Not Cancer Driver No 37 0.15 104 14 0.135 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0042176 Not Cancer Driver No 30 0.169 2 0 0.0 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0042176 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0042176 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0042176 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0042176 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0042176 Not Cancer Driver No 24 0.081 0 0 0.0 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0042176 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0042176 Not Cancer Driver No 26 0.129 88 16 0.182 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0042176 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0042176 Not Cancer Driver No 43 0.123 13 1 0.077 0
CST3_ENST00000376925 CST3 P01034 Cystatin-C chr20 GO:0042176 Not Cancer Driver No 17 0.116 31 1 0.032 2
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0042176 Not Cancer Driver No 59 0.123 14 1 0.071 12
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0042176 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 GO:0042176 Not Cancer Driver No 74 0.16 121 17 0.14 3
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0042176 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAM83D FAM83D Q9H4H8 Protein FAM83D chr20 GO:0042176 Not Cancer Driver No 70 0.12 273 29 0.106 0
FBXL20 FBXL20 Q96IG2 F-box/LRR-repeat protein 20 chr17 GO:0042176 Not Cancer Driver No 48 0.11 1 0 0.0 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0042176 Not Cancer Driver No 68 0.114 120 4 0.033 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0042176 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0042176 Not Cancer Driver No 74 0.149 184 30 0.163 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0042176 Not Cancer Driver No 74 0.138 38 5 0.132 171
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0042176 Not Cancer Driver No 65 0.15 288 42 0.146 62
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0042176 Not Cancer Driver No 153 0.182 36 9 0.25 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0042176 Census Yes 38 0.097 248 17 0.069 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0042176 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 GO:0042176 Not Cancer Driver No 109 0.14 528 74 0.14 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0042176 Not Cancer Driver No 154 0.129 686 96 0.14 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0042176 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0042176 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0042176 Not Cancer Driver No 39 0.145 16 3 0.188 0
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0042176 Not Cancer Driver No 24 0.076 73 5 0.068 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0042176 Not Cancer Driver No 119 0.138 63 3 0.048 104
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0042176 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0042176 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0042176 Not Cancer Driver No 998 0.214 209 40 0.191 1
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0042176 Not Cancer Driver No 59 0.139 90 8 0.089 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0042176 Not Cancer Driver No 33 0.134 23 5 0.217 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0042176 Census, Compendium Yes 56 0.114 297 37 0.125 0
MFSD8_ENST00000296468 MFSD8 Q8NHS3 Major facilitator superfamily domain-containing protein 8 chr4 GO:0042176 Not Cancer Driver No 69 0.133 16 3 0.188 16
MGAT3 MGAT3 Q09327 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase chr22 GO:0042176 Not Cancer Driver No 105 0.197 130 27 0.208 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0042176 Not Cancer Driver No 45 0.108 145 16 0.11 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0042176 Not Cancer Driver No 56 0.126 11 2 0.182 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0042176 Not Cancer Driver No 126 0.129 463 60 0.13 4
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0042176 Census, Compendium Yes 228 0.377 402 62 0.154 4
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0042176 Not Cancer Driver No 162 0.141 253 34 0.134 0
ODC1_ENST00000405333 ODC1 P11926 Ornithine decarboxylase chr2 GO:0042176 Not Cancer Driver No 46 0.1 33 7 0.212 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0042176 Not Cancer Driver No 52 0.123 290 31 0.107 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0042176 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0042176 Not Cancer Driver No 48 0.201 73 13 0.178 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0042176 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0042176 Not Cancer Driver No 75 0.116 202 15 0.074 0
PML PML P29590 Protein PML chr15 GO:0042176 Census, Compendium Yes 112 0.127 312 34 0.109 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0042176 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 GO:0042176 Not Cancer Driver No 110 0.115 201 19 0.095 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 GO:0042176 Not Cancer Driver No 100 0.11 135 14 0.104 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 GO:0042176 Not Cancer Driver No 69 0.129 152 19 0.125 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0042176 Not Cancer Driver No 139 0.152 214 28 0.131 0
QRICH2 QRICH2 Q9H0J4 Glutamine-rich protein 2 chr17 GO:0042176 Not Cancer Driver No 204 0.123 1369 171 0.125 0
RAB26 RAB26 Q9ULW5 Ras-related protein Rab-26 chr16 GO:0042176 Not Cancer Driver No 29 0.113 79 4 0.051 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0042176 Not Cancer Driver No 63 0.14 105 13 0.124 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0042176 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0042176 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF19A RNF19A Q9NV58 E3 ubiquitin-protein ligase RNF19A chr8 GO:0042176 Not Cancer Driver No 112 0.134 387 55 0.142 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0042176 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0042176 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0042176 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:0042176 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0042176 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0042176 Census Yes 57 0.192 96 17 0.177 2
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0042176 Not Cancer Driver No 29 0.149 39 7 0.179 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0042176 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0042176 Not Cancer Driver No 86 0.109 526 52 0.099 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0042176 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0042176 Not Cancer Driver No 33 0.093 164 12 0.073 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0042176 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNF8 SNF8 Q96H20 Vacuolar-sorting protein SNF8 chr17 GO:0042176 Not Cancer Driver No 30 0.116 10 2 0.2 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0042176 Not Cancer Driver No 38 0.087 416 37 0.089 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0042176 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0042176 Not Cancer Driver No 71 0.119 231 23 0.1 0
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0042176 Not Cancer Driver No 20 0.09 30 2 0.067 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0042176 Census Yes 55 0.114 199 19 0.095 2
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0042176 Not Cancer Driver No 16 0.208 77 16 0.208 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0042176 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0042176 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0042176 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0042176 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0042176 Not Cancer Driver No 30 0.134 8 2 0.25 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0042176 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 GO:0042176 Not Cancer Driver No 22 0.12 23 3 0.13 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0042176 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0042176 Not Cancer Driver No 48 0.104 229 28 0.122 0
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:0042176 Not Cancer Driver No 74 0.143 62 8 0.129 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0042176 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0042176 Not Cancer Driver No 82 0.131 581 79 0.136 8
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0042176 Not Cancer Driver No 35 0.118 271 33 0.122 0
UBXN2A UBXN2A P68543 UBX domain-containing protein 2A chr2 GO:0042176 Not Cancer Driver No 37 0.143 58 11 0.19 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0042176 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0042176 Not Cancer Driver No 59 0.119 86 6 0.07 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0042176 Not Cancer Driver No 161 0.122 539 68 0.126 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0042176 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0042176 Census, Compendium Yes 122 0.109 602 69 0.115 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0042176 Not Cancer Driver No 68 0.085 99 9 0.091 1
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0042176 Not Cancer Driver No 29 0.078 25 0 0.0 8
ZDHHC2 ZDHHC2 Q9UIJ5 Palmitoyltransferase ZDHHC2 chr8 GO:0042176 Not Cancer Driver No 47 0.128 73 6 0.082 0