Total number of protein in "GO:0042113" GO term: 90
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0042113 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0042113 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| AICDA | AICDA | Q9GZX7 | Single-stranded DNA cytosine deaminase | chr12 | GO:0042113 | Not Cancer Driver | No | 56 | 0.283 | 0 | 0 | 0.0 | 8 |
| AKAP17A | AKAP17A | Q02040 | A-kinase anchor protein 17A | chrX | GO:0042113 | Not Cancer Driver | No | 108 | 0.155 | 407 | 56 | 0.138 | 0 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0042113 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| BANK1 | BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | chr4 | GO:0042113 | Not Cancer Driver | No | 150 | 0.191 | 394 | 73 | 0.185 | 0 |
| BATF | BATF | Q16520 | Basic leucine zipper transcriptional factor ATF-like | chr14 | GO:0042113 | Not Cancer Driver | No | 28 | 0.224 | 119 | 25 | 0.21 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0042113 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0042113 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| BST2 | BST2 | Q10589 | Bone marrow stromal antigen 2 | chr19 | GO:0042113 | Not Cancer Driver | No | 19 | 0.106 | 20 | 0 | 0.0 | 0 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:0042113 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
| C17orf99 | C17orf99 | Q6UX52 | Protein IL-40 | chr17 | GO:0042113 | Not Cancer Driver | No | 16 | 0.06 | 84 | 3 | 0.036 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0042113 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CCR6_ENST00000349984 | CCR6 | P51684 | C-C chemokine receptor type 6 | chr6 | GO:0042113 | Not Cancer Driver | No | 56 | 0.15 | 13 | 2 | 0.154 | 0 |
| CD180 | CD180 | Q99467 | CD180 antigen | chr5 | GO:0042113 | Not Cancer Driver | No | 105 | 0.159 | 0 | 0 | 0.0 | 0 |
| CD19_ENST00000324662 | CD19 | P15391 | B-lymphocyte antigen CD19 | chr16 | GO:0042113 | Not Cancer Driver | No | 80 | 0.144 | 312 | 46 | 0.147 | 0 |
| CD22 | CD22 | P20273 | B-cell receptor CD22 | chr19 | GO:0042113 | Not Cancer Driver | No | 173 | 0.204 | 290 | 66 | 0.228 | 0 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0042113 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CD40LG | CD40LG | P29965 | CD40 ligand | chrX | GO:0042113 | Not Cancer Driver | No | 56 | 0.215 | 24 | 7 | 0.292 | 32 |
| CD79A | CD79A | P11912 | B-cell antigen receptor complex-associated protein alpha chain | chr19 | GO:0042113 | Census | Yes | 32 | 0.142 | 28 | 3 | 0.107 | 0 |
| CD86 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0042113 | Not Cancer Driver | No | 90 | 0.274 | 56 | 18 | 0.321 | 0 |
| CDH17 | CDH17 | Q12864 | Cadherin-17 | chr8 | GO:0042113 | Census | Yes | 166 | 0.2 | 186 | 35 | 0.188 | 0 |
| CHRNA4 | CHRNA4 | P43681 | Neuronal acetylcholine receptor subunit alpha-4 | chr20 | GO:0042113 | Not Cancer Driver | No | 144 | 0.23 | 186 | 33 | 0.177 | 2 |
| CHRNB2 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0042113 | Not Cancer Driver | No | 92 | 0.183 | 23 | 2 | 0.087 | 2 |
| CMTM7 | CMTM7 | Q96FZ5 | CKLF-like MARVEL transmembrane domain-containing protein 7 | chr3 | GO:0042113 | Not Cancer Driver | No | 25 | 0.143 | 0 | 0 | 0.0 | 0 |
| CXCR5 | CXCR5 | P32302 | C-X-C chemokine receptor type 5 | chr11 | GO:0042113 | Not Cancer Driver | No | 41 | 0.11 | 0 | 0 | 0.0 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0042113 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
| DOCK10 | DOCK10 | Q96BY6 | Dedicator of cytokinesis protein 10 | chr2 | GO:0042113 | Not Cancer Driver | No | 368 | 0.168 | 409 | 58 | 0.142 | 0 |
| DOCK11 | DOCK11 | Q5JSL3 | Dedicator of cytokinesis protein 11 | chrX | GO:0042113 | Not Cancer Driver | No | 312 | 0.151 | 240 | 29 | 0.121 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0042113 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0042113 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0042113 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0042113 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0042113 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0042113 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FCRL1 | FCRL1 | Q96LA6 | Fc receptor-like protein 1 | chr1 | GO:0042113 | Not Cancer Driver | No | 151 | 0.352 | 96 | 40 | 0.417 | 0 |
| FNIP1 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0042113 | Not Cancer Driver | No | 143 | 0.123 | 384 | 44 | 0.115 | 0 |
| GAPT | GAPT | Q8N292 | Protein GAPT | chr5 | GO:0042113 | Not Cancer Driver | No | 41 | 0.261 | 83 | 27 | 0.325 | 0 |
| GPR183 | GPR183 | P32249 | G-protein coupled receptor 183 | chr13 | GO:0042113 | Not Cancer Driver | No | 53 | 0.147 | 25 | 3 | 0.12 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | GO:0042113 | Not Cancer Driver | No | 182 | 0.168 | 749 | 132 | 0.176 | 0 |
| HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | GO:0042113 | Not Cancer Driver | No | 118 | 0.105 | 718 | 73 | 0.102 | 0 |
| HDAC9_ENST00000432645 | HDAC9 | Q9UKV0 | Histone deacetylase 9 | chr7 | GO:0042113 | Not Cancer Driver | No | 286 | 0.283 | 631 | 178 | 0.282 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0042113 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
| ICOSLG_ENST00000407780 | ICOSLG | O75144 | ICOS ligand | chr21 | GO:0042113 | Not Cancer Driver | No | 25 | 0.083 | 30 | 2 | 0.067 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0042113 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IKZF3 | IKZF3 | Q9UKT9 | Zinc finger protein Aiolos | chr17 | GO:0042113 | Census, Compendium | Yes | 106 | 0.208 | 284 | 60 | 0.211 | 1 |
| IL21 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0042113 | Not Cancer Driver | No | 34 | 0.21 | 70 | 18 | 0.257 | 1 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0042113 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IRF2BP2 | IRF2BP2 | Q7Z5L9 | Interferon regulatory factor 2-binding protein 2 | chr1 | GO:0042113 | Not Cancer Driver | No | 42 | 0.072 | 451 | 26 | 0.058 | 1 |
| IRF8 | IRF8 | Q02556 | Interferon regulatory factor 8 | chr16 | GO:0042113 | Not Cancer Driver | No | 80 | 0.188 | 77 | 20 | 0.26 | 2 |
| ITFG2 | ITFG2 | Q969R8 | KICSTOR complex protein ITFG2 | chr12 | GO:0042113 | Not Cancer Driver | No | 59 | 0.132 | 61 | 9 | 0.148 | 0 |
| ITM2A | ITM2A | O43736 | Integral membrane protein 2A | chrX | GO:0042113 | Not Cancer Driver | No | 75 | 0.285 | 26 | 9 | 0.346 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0042113 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| LAT2 | LAT2 | Q9GZY6 | Linker for activation of T-cells family member 2 | chr7 | GO:0042113 | Not Cancer Driver | No | 39 | 0.16 | 176 | 29 | 0.165 | 0 |
| LAX1 | LAX1 | Q8IWV1 | Lymphocyte transmembrane adapter 1 | chr1 | GO:0042113 | Not Cancer Driver | No | 61 | 0.153 | 228 | 32 | 0.14 | 0 |
| LFNG | LFNG | Q8NES3 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe | chr7 | GO:0042113 | Not Cancer Driver | No | 37 | 0.098 | 65 | 1 | 0.015 | 1 |
| LGALS1 | LGALS1 | P09382 | Galectin-1 | chr22 | GO:0042113 | Not Cancer Driver | No | 16 | 0.119 | 0 | 0 | 0.0 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0042113 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| LRRC8A_ENST00000372599 | LRRC8A | Q8IWT6 | Volume-regulated anion channel subunit LRRC8A | chr9 | GO:0042113 | Not Cancer Driver | No | 105 | 0.13 | 32 | 3 | 0.094 | 0 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0042113 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
| MFNG | MFNG | O00587 | Beta-1,3-N-acetylglucosaminyltransferase manic fringe | chr22 | GO:0042113 | Not Cancer Driver | No | 37 | 0.115 | 29 | 4 | 0.138 | 0 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0042113 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MS4A1_ENST00000345732 | MS4A1 | P11836 | B-lymphocyte antigen CD20 | chr11 | GO:0042113 | Not Cancer Driver | No | 73 | 0.246 | 83 | 23 | 0.277 | 0 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0042113 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0042113 | Census | Yes | 154 | 0.113 | 386 | 41 | 0.106 | 6 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0042113 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| NKX2-3 | NKX2-3 | Q8TAU0 | Homeobox protein Nkx-2.3 | chr10 | GO:0042113 | Not Cancer Driver | No | 31 | 0.085 | 212 | 27 | 0.127 | 0 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0042113 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0042113 | Not Cancer Driver | No | 31 | 0.104 | 26 | 4 | 0.154 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0042113 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0042113 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0042113 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PLCL2 | PLCL2 | Q9UPR0 | Inactive phospholipase C-like protein 2 | chr3 | GO:0042113 | Not Cancer Driver | No | 185 | 0.164 | 274 | 31 | 0.113 | 0 |
| POU2AF1 | POU2AF1 | Q16633 | POU domain class 2-associating factor 1 | chr11 | GO:0042113 | Census | Yes | 59 | 0.23 | 181 | 45 | 0.249 | 0 |
| PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | GO:0042113 | Census, Compendium | Yes | 205 | 0.306 | 148 | 40 | 0.27 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0042113 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| RAG2 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:0042113 | Not Cancer Driver | No | 118 | 0.224 | 85 | 23 | 0.271 | 6 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0042113 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0042113 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0042113 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| SKAP2 | SKAP2 | O75563 | Src kinase-associated phosphoprotein 2 | chr7 | GO:0042113 | Not Cancer Driver | No | 51 | 0.142 | 157 | 19 | 0.121 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0042113 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| ST3GAL1_ENST00000522652 | ST3GAL1 | Q11201 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | chr8 | GO:0042113 | Not Cancer Driver | No | 51 | 0.15 | 6 | 0 | 0.0 | 0 |
| SWAP70 | SWAP70 | Q9UH65 | Switch-associated protein 70 | chr11 | GO:0042113 | Not Cancer Driver | No | 44 | 0.075 | 271 | 18 | 0.066 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | GO:0042113 | Not Cancer Driver | No | 63 | 0.102 | 284 | 32 | 0.113 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0042113 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0042113 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TXLNA_ENST00000373610 | TXLNA | P40222 | Alpha-taxilin | chr1 | GO:0042113 | Not Cancer Driver | No | 68 | 0.125 | 481 | 59 | 0.123 | 0 |
| UNG | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0042113 | Not Cancer Driver | No | 34 | 0.109 | 96 | 13 | 0.135 | 1 |
| ZAP70 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0042113 | Not Cancer Driver | No | 126 | 0.204 | 117 | 17 | 0.145 | 8 |