Total number of protein in "GO:0042102" GO term: 99
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0042102 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0042102 | Not Cancer Driver | No | 14 | 0.095 | 61 | 6 | 0.098 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0042102 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| CARD11 | CARD11 | Q9BXL7 | Caspase recruitment domain-containing protein 11 | chr7 | GO:0042102 | Census, Compendium | Yes | 303 | 0.263 | 530 | 140 | 0.264 | 5 |
| CCDC88B | CCDC88B | A6NC98 | Coiled-coil domain-containing protein 88B | chr11 | GO:0042102 | Not Cancer Driver | No | 156 | 0.106 | 1152 | 130 | 0.113 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0042102 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0042102 | Not Cancer Driver | No | 81 | 0.217 | 23 | 1 | 0.043 | 0 |
| CD1D | CD1D | P15813 | Antigen-presenting glycoprotein CD1d | chr1 | GO:0042102 | Not Cancer Driver | No | 93 | 0.278 | 19 | 7 | 0.368 | 0 |
| CD209 | CD209 | Q9NNX6 | CD209 antigen | chr19 | GO:0042102 | Census | Yes | 116 | 0.287 | 42 | 8 | 0.19 | 0 |
| CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | GO:0042102 | Census | Yes | 29 | 0.1 | 54 | 9 | 0.167 | 0 |
| CD276 | CD276 | Q5ZPR3 | CD276 antigen | chr15 | GO:0042102 | Not Cancer Driver | No | 62 | 0.116 | 139 | 10 | 0.072 | 0 |
| CD28 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0042102 | Census | Yes | 42 | 0.191 | 18 | 10 | 0.556 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0042102 | Not Cancer Driver | No | 28 | 0.135 | 72 | 12 | 0.167 | 0 |
| CD40LG | CD40LG | P29965 | CD40 ligand | chrX | GO:0042102 | Not Cancer Driver | No | 56 | 0.215 | 24 | 7 | 0.292 | 32 |
| CD46_ENST00000358170 | CD46 | P15529 | Membrane cofactor protein | chr1 | GO:0042102 | Not Cancer Driver | No | 53 | 0.135 | 52 | 4 | 0.077 | 5 |
| CD55_ENST00000367064 | CD55 | P08174 | Complement decay-accelerating factor | chr1 | GO:0042102 | Not Cancer Driver | No | 45 | 0.118 | 128 | 13 | 0.102 | 1 |
| CD6 | CD6 | P30203 | T-cell differentiation antigen CD6 | chr11 | GO:0042102 | Not Cancer Driver | No | 91 | 0.136 | 268 | 41 | 0.153 | 0 |
| CD70_ENST00000245903 | CD70 | P32970 | CD70 antigen | chr19 | GO:0042102 | Not Cancer Driver | No | 33 | 0.171 | 11 | 2 | 0.182 | 0 |
| CD80_ENST00000478182 | CD80 | P33681 | T-lymphocyte activation antigen CD80 | chr3 | GO:0042102 | Not Cancer Driver | No | 50 | 0.174 | 26 | 5 | 0.192 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | GO:0042102 | Not Cancer Driver | No | 28 | 0.119 | 0 | 0 | 0.0 | 0 |
| CD86 | CD86 | P42081 | T-lymphocyte activation antigen CD86 | chr3 | GO:0042102 | Not Cancer Driver | No | 90 | 0.274 | 56 | 18 | 0.321 | 0 |
| CLECL1_ENST00000327839 | CLECL1 | Q8IZS7 | C-type lectin-like domain family 1 | chr12 | GO:0042102 | Not Cancer Driver | No | 18 | 0.108 | 0 | 0 | 0.0 | 0 |
| CORO1A | CORO1A | P31146 | Coronin-1A | chr16 | GO:0042102 | Not Cancer Driver | No | 51 | 0.111 | 126 | 15 | 0.119 | 1 |
| DHPS | DHPS | P49366 | Deoxyhypusine synthase | chr19 | GO:0042102 | Not Cancer Driver | No | 52 | 0.141 | 69 | 4 | 0.058 | 1 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | GO:0042102 | Not Cancer Driver | No | 50 | 0.104 | 152 | 21 | 0.138 | 0 |
| EBI3 | EBI3 | Q14213 | Interleukin-27 subunit beta | chr19 | GO:0042102 | Not Cancer Driver | No | 32 | 0.14 | 10 | 1 | 0.1 | 0 |
| EFNB1 | EFNB1 | P98172 | Ephrin-B1 | chrX | GO:0042102 | Not Cancer Driver | No | 46 | 0.133 | 126 | 14 | 0.111 | 19 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0042102 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0042102 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0042102 | Not Cancer Driver | No | 38 | 0.088 | 186 | 16 | 0.086 | 10 |
| GPAM | GPAM | Q9HCL2 | Glycerol-3-phosphate acyltransferase 1, mitochondrial | chr10 | GO:0042102 | Not Cancer Driver | No | 108 | 0.13 | 83 | 7 | 0.084 | 0 |
| HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:0042102 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0042102 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HHLA2_ENST00000489514 | HHLA2 | Q9UM44 | HERV-H LTR-associating protein 2 | chr3 | GO:0042102 | Not Cancer Driver | No | 85 | 0.205 | 57 | 10 | 0.175 | 0 |
| HLA-A_ENST00000376809 | HLA-A | P04439 | HLA class I histocompatibility antigen, A alpha chain | chr6 | GO:0042102 | Census, Compendium | Yes | 128 | 0.351 | 125 | 60 | 0.48 | 0 |
| HLA-DMB | HLA-DMB | P28068 | HLA class II histocompatibility antigen, DM beta chain | chr6 | GO:0042102 | Not Cancer Driver | No | 41 | 0.156 | 41 | 9 | 0.22 | 0 |
| HLA-DPA1 | HLA-DPA1 | P20036 | HLA class II histocompatibility antigen, DP alpha 1 chain | chr6 | GO:0042102 | Not Cancer Driver | No | 37 | 0.142 | 30 | 4 | 0.133 | 0 |
| HLA-DPB1 | HLA-DPB1 | P04440 | HLA class II histocompatibility antigen, DP beta 1 chain | chr6 | GO:0042102 | Not Cancer Driver | No | 38 | 0.147 | 39 | 4 | 0.103 | 0 |
| HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0042102 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0042102 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| ICOSLG_ENST00000407780 | ICOSLG | O75144 | ICOS ligand | chr21 | GO:0042102 | Not Cancer Driver | No | 25 | 0.083 | 30 | 2 | 0.067 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0042102 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0042102 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| IGFBP2 | IGFBP2 | P18065 | Insulin-like growth factor-binding protein 2 | chr2 | GO:0042102 | Not Cancer Driver | No | 32 | 0.098 | 171 | 24 | 0.14 | 0 |
| IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0042102 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
| IL12RB1_ENST00000593993 | IL12RB1 | P42701 | Interleukin-12 receptor subunit beta-1 | chr19 | GO:0042102 | Not Cancer Driver | No | 108 | 0.163 | 207 | 38 | 0.184 | 1 |
| IL15_ENST00000320650 | IL15 | P40933 | Interleukin-15 | chr4 | GO:0042102 | Not Cancer Driver | No | 25 | 0.154 | 6 | 1 | 0.167 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0042102 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0042102 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0042102 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| IL2 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0042102 | Census | Yes | 24 | 0.157 | 6 | 1 | 0.167 | 0 |
| IL21 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0042102 | Not Cancer Driver | No | 34 | 0.21 | 70 | 18 | 0.257 | 1 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0042102 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| IL23R | IL23R | Q5VWK5 | Interleukin-23 receptor | chr1 | GO:0042102 | Not Cancer Driver | No | 70 | 0.111 | 117 | 19 | 0.162 | 0 |
| IL27RA | IL27RA | Q6UWB1 | Interleukin-27 receptor subunit alpha | chr19 | GO:0042102 | Not Cancer Driver | No | 91 | 0.143 | 167 | 23 | 0.138 | 0 |
| IL2RA | IL2RA | P01589 | Interleukin-2 receptor subunit alpha | chr10 | GO:0042102 | Not Cancer Driver | No | 51 | 0.188 | 131 | 29 | 0.221 | 2 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0042102 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0042102 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0042102 | Census, Compendium | Yes | 102 | 0.111 | 315 | 40 | 0.127 | 2 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0042102 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| JAK3 | JAK3 | P52333 | Tyrosine-protein kinase JAK3 | chr19 | GO:0042102 | Census, Compendium | Yes | 167 | 0.149 | 63 | 10 | 0.159 | 7 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0042102 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0042102 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| LILRB2_ENST00000314446 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0042102 | Not Cancer Driver | No | 148 | 0.248 | 235 | 50 | 0.213 | 0 |
| NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0042102 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0042102 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0042102 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
| PDCD1LG2 | PDCD1LG2 | Q9BQ51 | Programmed cell death 1 ligand 2 | chr9 | GO:0042102 | Census, Compendium | Yes | 33 | 0.121 | 41 | 13 | 0.317 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | GO:0042102 | Not Cancer Driver | No | 38 | 0.131 | 29 | 2 | 0.069 | 5 |
| PRKCQ | PRKCQ | Q04759 | Protein kinase C theta type | chr10 | GO:0042102 | Not Cancer Driver | No | 147 | 0.208 | 28 | 9 | 0.321 | 0 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0042102 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0042102 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0042102 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RASAL3 | RASAL3 | Q86YV0 | RAS protein activator like-3 | chr19 | GO:0042102 | Not Cancer Driver | No | 114 | 0.113 | 536 | 68 | 0.127 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0042102 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0042102 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SASH3 | SASH3 | O75995 | SAM and SH3 domain-containing protein 3 | chrX | GO:0042102 | Not Cancer Driver | No | 59 | 0.155 | 327 | 49 | 0.15 | 0 |
| SELENOK | SELENOK | Q9Y6D0 | Selenoprotein K | chr3 | GO:0042102 | Not Cancer Driver | No | 10 | 0.106 | 47 | 6 | 0.128 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0042102 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0042102 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
| SLC7A1 | SLC7A1 | P30825 | High affinity cationic amino acid transporter 1 | chr13 | GO:0042102 | Not Cancer Driver | No | 89 | 0.141 | 17 | 3 | 0.176 | 0 |
| SPTA1_ENST00000368147 | SPTA1 | P02549 | Spectrin alpha chain, erythrocytic 1 | chr1 | GO:0042102 | Not Cancer Driver | No | 1046 | 0.432 | 707 | 294 | 0.416 | 21 |
| STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0042102 | Census, Compendium | Yes | 93 | 0.118 | 144 | 19 | 0.132 | 5 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0042102 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0042102 | Census | Yes | 89 | 0.117 | 80 | 6 | 0.075 | 1 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0042102 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TMIGD2 | TMIGD2 | Q96BF3 | Transmembrane and immunoglobulin domain-containing protein 2 | chr19 | GO:0042102 | Not Cancer Driver | No | 57 | 0.202 | 120 | 32 | 0.267 | 0 |
| TNFRSF13C | TNFRSF13C | Q96RJ3 | Tumor necrosis factor receptor superfamily member 13C | chr22 | GO:0042102 | Not Cancer Driver | No | 17 | 0.092 | 128 | 15 | 0.117 | 0 |
| TNFSF13B | TNFSF13B | Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | chr13 | GO:0042102 | Not Cancer Driver | No | 41 | 0.144 | 91 | 15 | 0.165 | 0 |
| TNFSF4 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0042102 | Not Cancer Driver | No | 28 | 0.153 | 1 | 0 | 0.0 | 0 |
| TNFSF9 | TNFSF9 | P41273 | Tumor necrosis factor ligand superfamily member 9 | chr19 | GO:0042102 | Not Cancer Driver | No | 32 | 0.126 | 39 | 4 | 0.103 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0042102 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | GO:0042102 | Not Cancer Driver | No | 148 | 0.125 | 213 | 29 | 0.136 | 0 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | GO:0042102 | Not Cancer Driver | No | 188 | 0.254 | 110 | 28 | 0.255 | 0 |
| VTCN1 | VTCN1 | Q7Z7D3 | V-set domain-containing T-cell activation inhibitor 1 | chr1 | GO:0042102 | Not Cancer Driver | No | 43 | 0.152 | 3 | 2 | 0.667 | 0 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0042102 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
| ZAP70 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0042102 | Not Cancer Driver | No | 126 | 0.204 | 117 | 17 | 0.145 | 8 |
| ZP3 | ZP3 | P21754 | Zona pellucida sperm-binding protein 3 | chr7 | GO:0042102 | Not Cancer Driver | No | 55 | 0.13 | 56 | 11 | 0.196 | 1 |
| ZP4 | ZP4 | Q12836 | Zona pellucida sperm-binding protein 4 | chr1 | GO:0042102 | Not Cancer Driver | No | 189 | 0.35 | 46 | 15 | 0.326 | 0 |