Total number of protein in "GO:0042058" GO term: 69
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0042058 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0042058 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0042058 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| AFAP1L2 | AFAP1L2 | Q8N4X5 | Actin filament-associated protein 1-like 2 | chr10 | GO:0042058 | Not Cancer Driver | No | 86 | 0.105 | 558 | 59 | 0.106 | 0 |
| AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | GO:0042058 | Not Cancer Driver | No | 23 | 0.131 | 20 | 2 | 0.1 | 0 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0042058 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AREG | AREG | P15514 | Amphiregulin | chr4 | GO:0042058 | Not Cancer Driver | No | 28 | 0.111 | 149 | 20 | 0.134 | 0 |
| BCAR3_ENST00000260502 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | GO:0042058 | Not Cancer Driver | No | 102 | 0.124 | 395 | 42 | 0.106 | 0 |
| BTC | BTC | P35070 | Probetacellulin | chr4 | GO:0042058 | Not Cancer Driver | No | 29 | 0.163 | 12 | 5 | 0.417 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0042058 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| CBLB | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0042058 | Census | Yes | 160 | 0.163 | 562 | 104 | 0.185 | 0 |
| CBLC_ENST00000647358 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | GO:0042058 | Census | Yes | 60 | 0.127 | 128 | 21 | 0.164 | 0 |
| CCDC88A_ENST00000642200 | CCDC88A | Q3V6T2 | Girdin | chr2 | GO:0042058 | Not Cancer Driver | No | 226 | 0.121 | 1481 | 173 | 0.117 | 0 |
| CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0042058 | Not Cancer Driver | No | 168 | 0.236 | 235 | 59 | 0.251 | 0 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0042058 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| CHMP6 | CHMP6 | Q96FZ7 | Charged multivesicular body protein 6 | chr17 | GO:0042058 | Not Cancer Driver | No | 26 | 0.129 | 88 | 16 | 0.182 | 0 |
| CNOT9_ENST00000273064 | CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | chr2 | GO:0042058 | Compendium | Yes | 42 | 0.14 | 30 | 0 | 0.0 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0042058 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DGKD | DGKD | Q16760 | Diacylglycerol kinase delta | chr2 | GO:0042058 | Not Cancer Driver | No | 160 | 0.132 | 441 | 60 | 0.136 | 0 |
| DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:0042058 | Not Cancer Driver | No | 21 | 0.114 | 4 | 1 | 0.25 | 0 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0042058 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0042058 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EPGN | EPGN | Q6UW88 | Epigen | chr4 | GO:0042058 | Not Cancer Driver | No | 16 | 0.104 | 0 | 0 | 0.0 | 0 |
| EREG | EREG | O14944 | Proepiregulin | chr4 | GO:0042058 | Not Cancer Driver | No | 26 | 0.154 | 10 | 3 | 0.3 | 0 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0042058 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| FASLG | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0042058 | Not Cancer Driver | No | 65 | 0.231 | 94 | 18 | 0.191 | 1 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0042058 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0042058 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0042058 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GPRC5A | GPRC5A | Q8NFJ5 | Retinoic acid-induced protein 3 | chr12 | GO:0042058 | Not Cancer Driver | No | 43 | 0.12 | 19 | 4 | 0.211 | 0 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | GO:0042058 | Not Cancer Driver | No | 97 | 0.145 | 454 | 60 | 0.132 | 0 |
| HBEGF | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0042058 | Not Cancer Driver | No | 16 | 0.077 | 63 | 3 | 0.048 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0042058 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0042058 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| IFI6_ENST00000361157 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0042058 | Not Cancer Driver | No | 12 | 0.092 | 7 | 0 | 0.0 | 0 |
| ITGA1 | ITGA1 | P56199 | Integrin alpha-1 | chr5 | GO:0042058 | Not Cancer Driver | No | 156 | 0.132 | 107 | 13 | 0.121 | 0 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0042058 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MVB12A | MVB12A | Q96EY5 | Multivesicular body subunit 12A | chr19 | GO:0042058 | Not Cancer Driver | No | 27 | 0.099 | 67 | 4 | 0.06 | 0 |
| MVB12B | MVB12B | Q9H7P6 | Multivesicular body subunit 12B | chr9 | GO:0042058 | Not Cancer Driver | No | 34 | 0.107 | 148 | 10 | 0.068 | 0 |
| MVP | MVP | Q14764 | Major vault protein | chr16 | GO:0042058 | Not Cancer Driver | No | 141 | 0.158 | 285 | 31 | 0.109 | 0 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0042058 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NEURL1 | NEURL1 | O76050 | E3 ubiquitin-protein ligase NEURL1 | chr10 | GO:0042058 | Not Cancer Driver | No | 62 | 0.108 | 153 | 11 | 0.072 | 0 |
| NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0042058 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
| PDE6G | PDE6G | P18545 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | chr17 | GO:0042058 | Not Cancer Driver | No | 15 | 0.172 | 58 | 11 | 0.19 | 0 |
| PDE6H | PDE6H | Q13956 | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | chr12 | GO:0042058 | Not Cancer Driver | No | 15 | 0.181 | 59 | 14 | 0.237 | 0 |
| PLAUR | PLAUR | Q03405 | Urokinase plasminogen activator surface receptor | chr19 | GO:0042058 | Not Cancer Driver | No | 49 | 0.146 | 18 | 5 | 0.278 | 0 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0042058 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| PTK6 | PTK6 | Q13882 | Protein-tyrosine kinase 6 | chr20 | GO:0042058 | Census | Yes | 42 | 0.093 | 12 | 0 | 0.0 | 0 |
| PTPN12 | PTPN12 | Q05209 | Tyrosine-protein phosphatase non-receptor type 12 | chr7 | GO:0042058 | Not Cancer Driver | No | 102 | 0.131 | 516 | 60 | 0.116 | 0 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0042058 | Not Cancer Driver | No | 57 | 0.137 | 120 | 14 | 0.117 | 0 |
| PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | GO:0042058 | Not Cancer Driver | No | 139 | 0.152 | 214 | 28 | 0.131 | 0 |
| PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0042058 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0042058 | Not Cancer Driver | No | 27 | 0.13 | 11 | 0 | 0.0 | 4 |
| RHBDF1 | RHBDF1 | Q96CC6 | Inactive rhomboid protein 1 | chr16 | GO:0042058 | Not Cancer Driver | No | 96 | 0.112 | 316 | 44 | 0.139 | 0 |
| RHBDF2 | RHBDF2 | Q6PJF5 | Inactive rhomboid protein 2 | chr17 | GO:0042058 | Not Cancer Driver | No | 93 | 0.109 | 284 | 36 | 0.127 | 2 |
| RNF115 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | GO:0042058 | Not Cancer Driver | No | 30 | 0.099 | 136 | 14 | 0.103 | 0 |
| RNF126 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | GO:0042058 | Not Cancer Driver | No | 33 | 0.106 | 182 | 22 | 0.121 | 0 |
| SHKBP1 | SHKBP1 | Q8TBC3 | SH3KBP1-binding protein 1 | chr19 | GO:0042058 | Not Cancer Driver | No | 93 | 0.132 | 281 | 32 | 0.114 | 0 |
| SNX5_ENST00000377759 | SNX5 | Q9Y5X3 | Sorting nexin-5 | chr20 | GO:0042058 | Not Cancer Driver | No | 33 | 0.082 | 91 | 13 | 0.143 | 0 |
| SNX6 | SNX6 | Q9UNH7 | Sorting nexin-6 | chr14 | GO:0042058 | Not Cancer Driver | No | 33 | 0.081 | 85 | 7 | 0.082 | 0 |
| SOCS4_ENST00000555846 | SOCS4 | Q8WXH5 | Suppressor of cytokine signaling 4 | chr14 | GO:0042058 | Not Cancer Driver | No | 43 | 0.098 | 136 | 13 | 0.096 | 0 |
| SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0042058 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
| SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0042058 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
| TGFA_ENST00000295400 | TGFA | P01135 | Protransforming growth factor alpha | chr2 | GO:0042058 | Not Cancer Driver | No | 20 | 0.125 | 0 | 0 | 0.0 | 0 |
| TSG101 | TSG101 | Q99816 | Tumor susceptibility gene 101 protein | chr11 | GO:0042058 | Not Cancer Driver | No | 46 | 0.118 | 159 | 23 | 0.145 | 0 |
| VPS25 | VPS25 | Q9BRG1 | Vacuolar protein-sorting-associated protein 25 | chr17 | GO:0042058 | Not Cancer Driver | No | 16 | 0.091 | 10 | 0 | 0.0 | 0 |
| WDR54 | WDR54 | Q9H977 | WD repeat-containing protein 54 | chr2 | GO:0042058 | Not Cancer Driver | No | 39 | 0.117 | 5 | 0 | 0.0 | 0 |
| ZFYVE28 | ZFYVE28 | Q9HCC9 | Lateral signaling target protein 2 homolog | chr4 | GO:0042058 | Not Cancer Driver | No | 132 | 0.149 | 420 | 67 | 0.16 | 0 |
| ZGPAT | ZGPAT | Q8N5A5 | Zinc finger CCCH-type with G patch domain-containing protein | chr20 | GO:0042058 | Not Cancer Driver | No | 75 | 0.141 | 346 | 49 | 0.142 | 0 |