Total number of protein in "GO:0040029" GO term: 88
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARID1A | ARID1A | O14497 | AT-rich interactive domain-containing protein 1A | chr1 | GO:0040029 | Census, Compendium | Yes | 275 | 0.12 | 1856 | 206 | 0.111 | 0 |
| ARID1B_ENST00000350026 | ARID1B | Q8NFD5 | AT-rich interactive domain-containing protein 1B | chr6 | GO:0040029 | Census, Compendium | Yes | 251 | 0.108 | 1890 | 206 | 0.109 | 0 |
| ARID4A | ARID4A | P29374 | AT-rich interactive domain-containing protein 4A | chr14 | GO:0040029 | Not Cancer Driver | No | 151 | 0.12 | 978 | 123 | 0.126 | 0 |
| ARID4B | ARID4B | Q4LE39 | AT-rich interactive domain-containing protein 4B | chr1 | GO:0040029 | Not Cancer Driver | No | 143 | 0.109 | 1005 | 118 | 0.117 | 0 |
| ASIP_ENST00000374954 | ASIP | P42127 | Agouti-signaling protein | chr20 | GO:0040029 | Not Cancer Driver | No | 16 | 0.121 | 36 | 9 | 0.25 | 0 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0040029 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0040029 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
| CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0040029 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
| CDYL_ENST00000328908 | CDYL | Q9Y232 | Chromodomain Y-like protein | chr6 | GO:0040029 | Not Cancer Driver | No | 99 | 0.166 | 346 | 61 | 0.176 | 0 |
| CENPV | CENPV | Q7Z7K6 | Centromere protein V | chr17 | GO:0040029 | Not Cancer Driver | No | 16 | 0.058 | 154 | 2 | 0.013 | 0 |
| CGGBP1_ENST00000309534 | CGGBP1 | Q9UFW8 | CGG triplet repeat-binding protein 1 | chr3 | GO:0040029 | Not Cancer Driver | No | 18 | 0.108 | 105 | 11 | 0.105 | 0 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0040029 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| CTCF | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | GO:0040029 | Census, Compendium | Yes | 151 | 0.208 | 481 | 83 | 0.173 | 1 |
| CTCFL_ENST00000371196 | CTCFL | Q8NI51 | Transcriptional repressor CTCFL | chr20 | GO:0040029 | Not Cancer Driver | No | 136 | 0.205 | 266 | 61 | 0.229 | 0 |
| DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | GO:0040029 | Not Cancer Driver | No | 38 | 0.166 | 21 | 3 | 0.143 | 0 |
| DNMT1_ENST00000340748 | DNMT1 | P26358 | DNA (cytosine-5)-methyltransferase 1 | chr19 | GO:0040029 | Not Cancer Driver | No | 203 | 0.126 | 702 | 78 | 0.111 | 4 |
| DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0040029 | Census, Compendium | Yes | 194 | 0.213 | 371 | 59 | 0.159 | 16 |
| DNMT3L_ENST00000628202 | DNMT3L | Q9UJW3 | DNA (cytosine-5)-methyltransferase 3-like | chr21 | GO:0040029 | Not Cancer Driver | No | 83 | 0.215 | 10 | 1 | 0.1 | 0 |
| EIF1 | EIF1 | P41567 | Eukaryotic translation initiation factor 1 | chr17 | GO:0040029 | Not Cancer Driver | No | 13 | 0.115 | 9 | 1 | 0.111 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0040029 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| EXOSC10 | EXOSC10 | Q01780 | Exosome component 10 | chr1 | GO:0040029 | Not Cancer Driver | No | 87 | 0.098 | 375 | 35 | 0.093 | 0 |
| EZH1 | EZH1 | Q92800 | Histone-lysine N-methyltransferase EZH1 | chr17 | GO:0040029 | Not Cancer Driver | No | 82 | 0.11 | 213 | 21 | 0.099 | 0 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0040029 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
| FAM172A | FAM172A | Q8WUF8 | Cotranscriptional regulator FAM172A | chr5 | GO:0040029 | Not Cancer Driver | No | 53 | 0.127 | 109 | 19 | 0.174 | 0 |
| FAM47E | FAM47E | Q6ZV65 | Protein FAM47E | chr4 | GO:0040029 | Not Cancer Driver | No | 21 | 0.053 | 143 | 6 | 0.042 | 0 |
| GLMN | GLMN | Q92990 | Glomulin | chr1 | GO:0040029 | Not Cancer Driver | No | 49 | 0.082 | 37 | 6 | 0.162 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0040029 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0040029 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
| H2AFY2 | MACROH2A2 | Q9P0M6 | Core histone macro-H2A.2 | chr10 | GO:0040029 | Not Cancer Driver | No | 59 | 0.159 | 171 | 32 | 0.187 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0040029 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0040029 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0040029 | Not Cancer Driver | No | 47 | 0.098 | 135 | 10 | 0.074 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | GO:0040029 | Not Cancer Driver | No | 182 | 0.168 | 749 | 132 | 0.176 | 0 |
| HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | GO:0040029 | Not Cancer Driver | No | 118 | 0.105 | 718 | 73 | 0.102 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0040029 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HELLS_ENST00000348459 | HELLS | Q9NRZ9 | Lymphoid-specific helicase | chr10 | GO:0040029 | Not Cancer Driver | No | 78 | 0.093 | 227 | 25 | 0.11 | 0 |
| HIST1H3A | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 18 | 0.132 | 51 | 6 | 0.118 | 1 |
| HIST1H3B | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 80 | 0.588 | 51 | 24 | 0.471 | 1 |
| HIST1H3C | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 45 | 0.331 | 51 | 25 | 0.49 | 1 |
| HIST1H3D | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 49 | 0.36 | 51 | 20 | 0.392 | 1 |
| HIST1H3E_ENST00000614911 | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 36 | 0.265 | 51 | 11 | 0.216 | 1 |
| HIST1H3F | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 38 | 0.279 | 51 | 11 | 0.216 | 1 |
| HIST1H3G | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 33 | 0.243 | 51 | 13 | 0.255 | 1 |
| HIST1H3H | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 29 | 0.213 | 51 | 10 | 0.196 | 1 |
| HIST1H3I | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 44 | 0.324 | 51 | 15 | 0.294 | 1 |
| HIST1H3J | H3C12 | P68431 | Histone H3.1 | chr6 | GO:0040029 | Not Cancer Driver | No | 21 | 0.154 | 51 | 10 | 0.196 | 1 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | GO:0040029 | Not Cancer Driver | No | 77 | 0.093 | 504 | 45 | 0.089 | 0 |
| IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | GO:0040029 | Not Cancer Driver | No | 155 | 0.197 | 419 | 90 | 0.215 | 0 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0040029 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| JARID2 | JARID2 | Q92833 | Protein Jumonji | chr6 | GO:0040029 | Not Cancer Driver | No | 190 | 0.152 | 724 | 113 | 0.156 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0040029 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0040029 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KDM1B_ENST00000449850 | KDM1B | Q8NB78 | Lysine-specific histone demethylase 1B | chr6 | GO:0040029 | Not Cancer Driver | No | 81 | 0.099 | 74 | 11 | 0.149 | 0 |
| KLF2 | KLF2 | Q9Y5W3 | Krueppel-like factor 2 | chr19 | GO:0040029 | Not Cancer Driver | No | 13 | 0.037 | 280 | 4 | 0.014 | 0 |
| LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | GO:0040029 | Not Cancer Driver | No | 116 | 0.151 | 520 | 74 | 0.142 | 0 |
| MBD2 | MBD2 | Q9UBB5 | Methyl-CpG-binding domain protein 2 | chr18 | GO:0040029 | Not Cancer Driver | No | 26 | 0.063 | 384 | 25 | 0.065 | 0 |
| MBD3 | MBD3 | O95983 | Methyl-CpG-binding domain protein 3 | chr19 | GO:0040029 | Not Cancer Driver | No | 50 | 0.172 | 246 | 46 | 0.187 | 0 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0040029 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0040029 | Not Cancer Driver | No | 74 | 0.128 | 274 | 29 | 0.106 | 0 |
| MORC1 | MORC1 | Q86VD1 | MORC family CW-type zinc finger protein 1 | chr3 | GO:0040029 | Not Cancer Driver | No | 300 | 0.305 | 252 | 77 | 0.306 | 0 |
| MTA1 | MTA1 | Q13330 | Metastasis-associated protein MTA1 | chr14 | GO:0040029 | Not Cancer Driver | No | 92 | 0.129 | 327 | 42 | 0.128 | 0 |
| NDN | NDN | Q99608 | Necdin | chr15 | GO:0040029 | Not Cancer Driver | No | 123 | 0.383 | 117 | 42 | 0.359 | 0 |
| PADI2 | PADI2 | Q9Y2J8 | Protein-arginine deiminase type-2 | chr1 | GO:0040029 | Not Cancer Driver | No | 121 | 0.182 | 60 | 18 | 0.3 | 0 |
| PCGF3 | PCGF3 | Q3KNV8 | Polycomb group RING finger protein 3 | chr4 | GO:0040029 | Not Cancer Driver | No | 38 | 0.157 | 47 | 11 | 0.234 | 0 |
| PCGF5 | PCGF5 | Q86SE9 | Polycomb group RING finger protein 5 | chr10 | GO:0040029 | Not Cancer Driver | No | 31 | 0.121 | 52 | 5 | 0.096 | 0 |
| PHF2 | PHF2 | O75151 | Lysine-specific demethylase PHF2 | chr9 | GO:0040029 | Not Cancer Driver | No | 131 | 0.12 | 725 | 80 | 0.11 | 0 |
| PRDM14 | PRDM14 | Q9GZV8 | PR domain zinc finger protein 14 | chr8 | GO:0040029 | Not Cancer Driver | No | 122 | 0.214 | 179 | 37 | 0.207 | 0 |
| PRMT7_ENST00000441236 | PRMT7 | Q9NVM4 | Protein arginine N-methyltransferase 7 | chr16 | GO:0040029 | Not Cancer Driver | No | 71 | 0.103 | 39 | 1 | 0.026 | 3 |
| RBM15 | RBM15 | Q96T37 | RNA-binding protein 15 | chr1 | GO:0040029 | Census, Compendium | Yes | 118 | 0.121 | 686 | 91 | 0.133 | 0 |
| RBM15B | RBM15B | Q8NDT2 | Putative RNA-binding protein 15B | chr3 | GO:0040029 | Not Cancer Driver | No | 76 | 0.085 | 597 | 48 | 0.08 | 0 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | GO:0040029 | Not Cancer Driver | No | 287 | 0.116 | 1355 | 164 | 0.121 | 0 |
| RLIM_ENST00000349225 | RLIM | Q9NVW2 | E3 ubiquitin-protein ligase RLIM | chrX | GO:0040029 | Not Cancer Driver | No | 106 | 0.17 | 545 | 94 | 0.172 | 4 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0040029 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0040029 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0040029 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
| SMARCD1 | SMARCD1 | Q96GM5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | chr12 | GO:0040029 | Census, Compendium | Yes | 48 | 0.093 | 216 | 18 | 0.083 | 2 |
| SMCHD1 | SMCHD1 | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | chr18 | GO:0040029 | Not Cancer Driver | No | 240 | 0.12 | 342 | 45 | 0.132 | 45 |
| SPHK2 | SPHK2 | Q9NRA0 | Sphingosine kinase 2 | chr19 | GO:0040029 | Not Cancer Driver | No | 82 | 0.125 | 293 | 39 | 0.133 | 0 |
| SUZ12 | SUZ12 | Q15022 | Polycomb protein SUZ12 | chr17 | GO:0040029 | Census, Compendium | Yes | 83 | 0.112 | 483 | 46 | 0.095 | 3 |
| TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0040029 | Not Cancer Driver | No | 75 | 0.183 | 185 | 31 | 0.168 | 0 |
| TFAP2C | TFAP2C | Q92754 | Transcription factor AP-2 gamma | chr20 | GO:0040029 | Not Cancer Driver | No | 76 | 0.169 | 282 | 41 | 0.145 | 0 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0040029 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| WBP2_ENST00000254806 | WBP2 | Q969T9 | WW domain-binding protein 2 | chr17 | GO:0040029 | Not Cancer Driver | No | 26 | 0.1 | 102 | 6 | 0.059 | 1 |
| YTHDC1_ENST00000344157 | YTHDC1 | Q96MU7 | YTH domain-containing protein 1 | chr4 | GO:0040029 | Not Cancer Driver | No | 137 | 0.188 | 597 | 117 | 0.196 | 0 |
| ZDBF2 | ZDBF2 | Q9HCK1 | DBF4-type zinc finger-containing protein 2 | chr2 | GO:0040029 | Not Cancer Driver | No | 510 | 0.217 | 1664 | 380 | 0.228 | 0 |
| ZFP57_ENST00000376881 | ZFP57 | Q9NU63 | Zinc finger protein 57 homolog | chr6 | GO:0040029 | Not Cancer Driver | No | 82 | 0.181 | 153 | 33 | 0.216 | 3 |
| ZNF335 | ZNF335 | Q9H4Z2 | Zinc finger protein 335 | chr20 | GO:0040029 | Not Cancer Driver | No | 185 | 0.138 | 942 | 133 | 0.141 | 1 |
| ZNFX1_ENST00000371752 | ZNFX1 | Q9P2E3 | NFX1-type zinc finger-containing protein 1 | chr20 | GO:0040029 | Not Cancer Driver | No | 228 | 0.119 | 354 | 49 | 0.138 | 0 |