Total number of protein in "GO:0040007" GO term: 223
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0040007 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0040007 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
ADAM15 | ADAM15 | Q13444 | Disintegrin and metalloproteinase domain-containing protein 15 | chr1 | GO:0040007 | Not Cancer Driver | No | 104 | 0.121 | 213 | 29 | 0.136 | 0 |
ADARB1 | ADARB1 | P78563 | Double-stranded RNA-specific editase 1 | chr21 | GO:0040007 | Not Cancer Driver | No | 102 | 0.138 | 348 | 34 | 0.098 | 1 |
ADPRHL1 | ADPRHL1 | Q8NDY3 | Inactive ADP-ribosyltransferase ARH2 | chr13 | GO:0040007 | Not Cancer Driver | No | 52 | 0.147 | 32 | 7 | 0.219 | 0 |
ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0040007 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0040007 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
AKAP13_ENST00000394518 | AKAP13 | Q12802 | A-kinase anchor protein 13 | chr15 | GO:0040007 | Not Cancer Driver | No | 359 | 0.128 | 2091 | 258 | 0.123 | 0 |
ALCAM | ALCAM | Q13740 | CD166 antigen | chr3 | GO:0040007 | Not Cancer Driver | No | 89 | 0.153 | 96 | 19 | 0.198 | 0 |
AMH | AMH | P03971 | Muellerian-inhibiting factor | chr19 | GO:0040007 | Not Cancer Driver | No | 19 | 0.034 | 207 | 4 | 0.019 | 9 |
APBA1 | APBA1 | Q02410 | Amyloid-beta A4 precursor protein-binding family A member 1 | chr9 | GO:0040007 | Not Cancer Driver | No | 149 | 0.178 | 556 | 103 | 0.185 | 0 |
APOA5 | APOA5 | Q6Q788 | Apolipoprotein A-V | chr11 | GO:0040007 | Not Cancer Driver | No | 51 | 0.139 | 178 | 26 | 0.146 | 0 |
APOD | APOD | P05090 | Apolipoprotein D | chr3 | GO:0040007 | Not Cancer Driver | No | 34 | 0.18 | 13 | 2 | 0.154 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0040007 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
AR | AR | P10275 | Androgen receptor | chrX | GO:0040007 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
ARID5B | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0040007 | Not Cancer Driver | No | 162 | 0.136 | 769 | 95 | 0.124 | 0 |
ATF5_ENST00000595125 | ATF5 | Q9Y2D1 | Cyclic AMP-dependent transcription factor ATF-5 | chr19 | GO:0040007 | Not Cancer Driver | No | 47 | 0.167 | 239 | 40 | 0.167 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0040007 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0040007 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
AUTS2 | AUTS2 | Q8WXX7 | Autism susceptibility gene 2 protein | chr7 | GO:0040007 | Not Cancer Driver | No | 219 | 0.174 | 1218 | 213 | 0.175 | 0 |
BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0040007 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
BDNF_ENST00000439476 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0040007 | Not Cancer Driver | No | 47 | 0.19 | 79 | 19 | 0.241 | 1 |
BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0040007 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
BMPR1B_ENST00000394931 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0040007 | Not Cancer Driver | No | 84 | 0.167 | 64 | 12 | 0.188 | 5 |
BNC2 | BNC2 | Q6ZN30 | Zinc finger protein basonuclin-2 | chr9 | GO:0040007 | Not Cancer Driver | No | 242 | 0.22 | 682 | 150 | 0.22 | 1 |
CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0040007 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
CCM2_ENST00000258781 | CCM2 | Q9BSQ5 | Cerebral cavernous malformations 2 protein | chr7 | GO:0040007 | Not Cancer Driver | No | 58 | 0.131 | 132 | 8 | 0.061 | 3 |
CCN3 | CCN3 | P48745 | CCN family member 3 | chr8 | GO:0040007 | Not Cancer Driver | No | 66 | 0.185 | 19 | 1 | 0.053 | 0 |
CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | GO:0040007 | Not Cancer Driver | No | 68 | 0.115 | 278 | 40 | 0.144 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0040007 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0040007 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
CELA1 | CELA1 | Q9UNI1 | Chymotrypsin-like elastase family member 1 | chr12 | GO:0040007 | Not Cancer Driver | No | 48 | 0.186 | 20 | 0 | 0.0 | 0 |
CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0040007 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
CHRNA1_ENST00000348749 | CHRNA1 | P02708 | Acetylcholine receptor subunit alpha | chr2 | GO:0040007 | Not Cancer Driver | No | 86 | 0.188 | 9 | 1 | 0.111 | 12 |
CHRND | CHRND | Q07001 | Acetylcholine receptor subunit delta | chr2 | GO:0040007 | Not Cancer Driver | No | 110 | 0.213 | 71 | 19 | 0.268 | 7 |
CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | GO:0040007 | Not Cancer Driver | No | 24 | 0.095 | 49 | 4 | 0.082 | 0 |
COBL_ENST00000265136 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0040007 | Not Cancer Driver | No | 233 | 0.185 | 1149 | 216 | 0.188 | 0 |
COL3A1 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0040007 | Census | Yes | 402 | 0.274 | 1182 | 337 | 0.285 | 103 |
COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0040007 | Not Cancer Driver | No | 97 | 0.128 | 306 | 52 | 0.17 | 61 |
CPQ | CPQ | Q9Y646 | Carboxypeptidase Q | chr8 | GO:0040007 | Not Cancer Driver | No | 110 | 0.233 | 3 | 0 | 0.0 | 0 |
CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0040007 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
CTC1 | CTC1 | Q2NKJ3 | CST complex subunit CTC1 | chr17 | GO:0040007 | Not Cancer Driver | No | 142 | 0.117 | 103 | 8 | 0.078 | 9 |
CTR9 | CTR9 | Q6PD62 | RNA polymerase-associated protein CTR9 homolog | chr11 | GO:0040007 | Not Cancer Driver | No | 164 | 0.14 | 385 | 48 | 0.125 | 0 |
CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0040007 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
CYFIP2 | CYFIP2 | Q96F07 | Cytoplasmic FMR1-interacting protein 2 | chr5 | GO:0040007 | Not Cancer Driver | No | 211 | 0.165 | 86 | 11 | 0.128 | 3 |
CYP19A1_ENST00000396404 | CYP19A1 | P11511 | Aromatase | chr15 | GO:0040007 | Not Cancer Driver | No | 91 | 0.181 | 2 | 1 | 0.5 | 5 |
DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0040007 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
DDR2 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0040007 | Census | Yes | 192 | 0.225 | 118 | 34 | 0.288 | 7 |
DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0040007 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0040007 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
ECM1_ENST00000369047 | ECM1 | Q16610 | Extracellular matrix protein 1 | chr1 | GO:0040007 | Not Cancer Driver | No | 91 | 0.169 | 219 | 28 | 0.128 | 1 |
EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0040007 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0040007 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0040007 | Not Cancer Driver | No | 142 | 0.117 | 585 | 71 | 0.121 | 0 |
EN1 | EN1 | Q05925 | Homeobox protein engrailed-1 | chr2 | GO:0040007 | Not Cancer Driver | No | 42 | 0.107 | 357 | 30 | 0.084 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0040007 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0040007 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0040007 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0040007 | Census, Compendium | Yes | 150 | 0.197 | 5 | 0 | 0.0 | 35 |
ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0040007 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
EREG | EREG | O14944 | Proepiregulin | chr4 | GO:0040007 | Not Cancer Driver | No | 26 | 0.154 | 10 | 3 | 0.3 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0040007 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
ETNK2_ENST00000367202 | ETNK2 | Q9NVF9 | Ethanolamine kinase 2 | chr1 | GO:0040007 | Not Cancer Driver | No | 46 | 0.119 | 38 | 34 | 0.895 | 0 |
EVC | EVC | P57679 | Ellis-van Creveld syndrome protein | chr4 | GO:0040007 | Not Cancer Driver | No | 143 | 0.144 | 373 | 60 | 0.161 | 4 |
EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0040007 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
EYS | EYS | Q5T1H1 | Protein eyes shut homolog | chr6 | GO:0040007 | Not Cancer Driver | No | 447 | 0.141 | 109 | 9 | 0.083 | 16 |
FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0040007 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
FGF1_ENST00000612258 | FGF1 | P05230 | Fibroblast growth factor 1 | chr5 | GO:0040007 | Not Cancer Driver | No | 30 | 0.194 | 29 | 2 | 0.069 | 0 |
FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0040007 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0040007 | Census, Compendium | Yes | 173 | 0.215 | 241 | 26 | 0.108 | 37 |
FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | GO:0040007 | Not Cancer Driver | No | 71 | 0.172 | 160 | 25 | 0.156 | 0 |
FLVCR1 | FLVCR1 | Q9Y5Y0 | Feline leukemia virus subgroup C receptor-related protein 1 | chr1 | GO:0040007 | Not Cancer Driver | No | 58 | 0.105 | 117 | 14 | 0.12 | 4 |
FMN1 | FMN1 | Q68DA7 | Formin-1 | chr15 | GO:0040007 | Not Cancer Driver | No | 117 | 0.082 | 983 | 67 | 0.068 | 0 |
FOXL2 | FOXL2 | P58012 | Forkhead box protein L2 | chr3 | GO:0040007 | Census, Compendium | Yes | 39 | 0.104 | 257 | 20 | 0.078 | 26 |
FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0040007 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0040007 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
G6PC | G6PC1 | P35575 | Glucose-6-phosphatase catalytic subunit 1 | chr17 | GO:0040007 | Not Cancer Driver | No | 67 | 0.188 | 0 | 0 | 0.0 | 54 |
GAP43_ENST00000305124 | GAP43 | P17677 | Neuromodulin | chr3 | GO:0040007 | Not Cancer Driver | No | 79 | 0.332 | 238 | 79 | 0.332 | 0 |
GAS2 | GAS2 | O43903 | Growth arrest-specific protein 2 | chr11 | GO:0040007 | Not Cancer Driver | No | 73 | 0.233 | 92 | 16 | 0.174 | 0 |
GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0040007 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0040007 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0040007 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
GPR149 | GPR149 | Q86SP6 | Probable G-protein coupled receptor 149 | chr3 | GO:0040007 | Not Cancer Driver | No | 180 | 0.246 | 286 | 74 | 0.259 | 0 |
GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0040007 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
GRHL2 | GRHL2 | Q6ISB3 | Grainyhead-like protein 2 homolog | chr8 | GO:0040007 | Not Cancer Driver | No | 95 | 0.152 | 258 | 43 | 0.167 | 2 |
H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0040007 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0040007 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0040007 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | GO:0040007 | Not Cancer Driver | No | 59 | 0.088 | 622 | 57 | 0.092 | 0 |
HEG1 | HEG1 | Q9ULI3 | Protein HEG homolog 1 | chr3 | GO:0040007 | Not Cancer Driver | No | 173 | 0.125 | 974 | 135 | 0.139 | 0 |
HELT | HELT | A6NFD8 | Hairy and enhancer of split-related protein HELT | chr4 | GO:0040007 | Not Cancer Driver | No | 39 | 0.161 | 131 | 21 | 0.16 | 0 |
HESX1 | HESX1 | Q9UBX0 | Homeobox expressed in ES cells 1 | chr3 | GO:0040007 | Not Cancer Driver | No | 32 | 0.173 | 59 | 9 | 0.153 | 6 |
HOXA5 | HOXA5 | P20719 | Homeobox protein Hox-A5 | chr7 | GO:0040007 | Not Cancer Driver | No | 43 | 0.159 | 209 | 37 | 0.177 | 0 |
HOXD13 | HOXD13 | P35453 | Homeobox protein Hox-D13 | chr2 | GO:0040007 | Census, Compendium | Yes | 43 | 0.125 | 113 | 12 | 0.106 | 9 |
IER3IP1 | IER3IP1 | Q9Y5U9 | Immediate early response 3-interacting protein 1 | chr18 | GO:0040007 | Not Cancer Driver | No | 3 | 0.037 | 0 | 0 | 0.0 | 2 |
IGFBP1 | IGFBP1 | P08833 | Insulin-like growth factor-binding protein 1 | chr7 | GO:0040007 | Not Cancer Driver | No | 47 | 0.181 | 42 | 7 | 0.167 | 0 |
IHH | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0040007 | Not Cancer Driver | No | 58 | 0.141 | 111 | 15 | 0.135 | 6 |
KAT2A | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | GO:0040007 | Not Cancer Driver | No | 88 | 0.105 | 251 | 17 | 0.068 | 0 |
KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0040007 | Not Cancer Driver | No | 219 | 0.142 | 388 | 58 | 0.149 | 0 |
KIF26B | KIF26B | Q2KJY2 | Kinesin-like protein KIF26B | chr1 | GO:0040007 | Not Cancer Driver | No | 369 | 0.175 | 1412 | 198 | 0.14 | 0 |
KLF2 | KLF2 | Q9Y5W3 | Krueppel-like factor 2 | chr19 | GO:0040007 | Not Cancer Driver | No | 13 | 0.037 | 280 | 4 | 0.014 | 0 |
KLK6 | KLK6 | Q92876 | Kallikrein-6 | chr19 | GO:0040007 | Not Cancer Driver | No | 62 | 0.254 | 28 | 12 | 0.429 | 0 |
KMT2D | KMT2D | O14686 | Histone-lysine N-methyltransferase 2D | chr12 | GO:0040007 | Census, Compendium | Yes | 773 | 0.14 | 4386 | 552 | 0.126 | 13 |
LAMB2 | LAMB2 | P55268 | Laminin subunit beta-2 | chr3 | GO:0040007 | Not Cancer Driver | No | 234 | 0.13 | 463 | 67 | 0.145 | 9 |
LARGE1 | LARGE1 | O95461 | Xylosyl- and glucuronyltransferase LARGE1 | chr22 | GO:0040007 | Not Cancer Driver | No | 131 | 0.173 | 92 | 16 | 0.174 | 4 |
LEP | LEP | P41159 | Leptin | chr7 | GO:0040007 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
LEPR | LEPR | P48357 | Leptin receptor | chr1 | GO:0040007 | Not Cancer Driver | No | 243 | 0.209 | 57 | 11 | 0.193 | 0 |
LGR6 | LGR6 | Q9HBX8 | Leucine-rich repeat-containing G-protein coupled receptor 6 | chr1 | GO:0040007 | Not Cancer Driver | No | 163 | 0.169 | 101 | 16 | 0.158 | 0 |
LLPH_ENST00000446587 | LLPH | Q9BRT6 | Protein LLP homolog | chr12 | GO:0040007 | Not Cancer Driver | No | 15 | 0.116 | 113 | 14 | 0.124 | 0 |
LRP4 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 | chr11 | GO:0040007 | Not Cancer Driver | No | 233 | 0.122 | 265 | 28 | 0.106 | 11 |
LY6E_ENST00000522024 | LY6E | Q16553 | Lymphocyte antigen 6E | chr8 | GO:0040007 | Not Cancer Driver | No | 13 | 0.099 | 0 | 0 | 0.0 | 0 |
LZTS2 | LZTS2 | Q9BRK4 | Leucine zipper putative tumor suppressor 2 | chr10 | GO:0040007 | Not Cancer Driver | No | 78 | 0.117 | 508 | 66 | 0.13 | 0 |
MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0040007 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0040007 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
MESP1 | MESP1 | Q9BRJ9 | Mesoderm posterior protein 1 | chr15 | GO:0040007 | Not Cancer Driver | No | 8 | 0.03 | 247 | 7 | 0.028 | 0 |
MEX3C | MEX3C | Q5U5Q3 | RNA-binding E3 ubiquitin-protein ligase MEX3C | chr18 | GO:0040007 | Not Cancer Driver | No | 54 | 0.082 | 475 | 32 | 0.067 | 0 |
MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0040007 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0040007 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
MTPN | MTPN | P58546 | Myotrophin | chr7 | GO:0040007 | Not Cancer Driver | No | 11 | 0.093 | 11 | 3 | 0.273 | 0 |
MUSTN1 | MUSTN1 | Q8IVN3 | Musculoskeletal embryonic nuclear protein 1 | chr3 | GO:0040007 | Not Cancer Driver | No | 11 | 0.134 | 82 | 11 | 0.134 | 0 |
NBN | NBN | O60934 | Nibrin | chr8 | GO:0040007 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0040007 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
NINJ1 | NINJ1 | Q92982 | Ninjurin-1 | chr9 | GO:0040007 | Not Cancer Driver | No | 17 | 0.112 | 29 | 0 | 0.0 | 0 |
NLGN4X_ENST00000381093 | NLGN4X | Q8N0W4 | Neuroligin-4, X-linked | chrX | GO:0040007 | Not Cancer Driver | No | 279 | 0.342 | 211 | 81 | 0.384 | 0 |
NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0040007 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0040007 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0040007 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
NRP2 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0040007 | Not Cancer Driver | No | 161 | 0.173 | 207 | 45 | 0.217 | 0 |
OSTN | OSTN | P61366 | Osteocrin | chr3 | GO:0040007 | Not Cancer Driver | No | 30 | 0.226 | 54 | 13 | 0.241 | 0 |
PALB2 | PALB2 | Q86YC2 | Partner and localizer of BRCA2 | chr16 | GO:0040007 | Census | Yes | 124 | 0.105 | 769 | 77 | 0.1 | 1 |
PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0040007 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
PDLIM5_ENST00000317968 | PDLIM5 | Q96HC4 | PDZ and LIM domain protein 5 | chr4 | GO:0040007 | Not Cancer Driver | No | 89 | 0.149 | 372 | 57 | 0.153 | 0 |
PKDCC | PKDCC | Q504Y2 | Extracellular tyrosine-protein kinase PKDCC | chr2 | GO:0040007 | Not Cancer Driver | No | 36 | 0.073 | 124 | 0 | 0.0 | 0 |
PLAG1_ENST00000429357 | PLAG1 | Q6DJT9 | Zinc finger protein PLAG1 | chr8 | GO:0040007 | Census, Compendium | Yes | 108 | 0.216 | 209 | 48 | 0.23 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | GO:0040007 | Not Cancer Driver | No | 677 | 0.145 | 2130 | 272 | 0.128 | 2 |
PLEKHA1 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0040007 | Not Cancer Driver | No | 61 | 0.151 | 191 | 32 | 0.168 | 0 |
PLG | PLG | P00747 | Plasminogen | chr6 | GO:0040007 | Not Cancer Driver | No | 242 | 0.299 | 230 | 64 | 0.278 | 9 |
PPP1R13L_ENST00000360957 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | GO:0040007 | Not Cancer Driver | No | 117 | 0.141 | 657 | 90 | 0.137 | 0 |
PPP3CA | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0040007 | Compendium | Yes | 85 | 0.163 | 140 | 27 | 0.193 | 7 |
PRLR | PRLR | P16471 | Prolactin receptor | chr5 | GO:0040007 | Not Cancer Driver | No | 154 | 0.248 | 282 | 70 | 0.248 | 2 |
PSAP | PSAP | P07602 | Prosaposin | chr10 | GO:0040007 | Not Cancer Driver | No | 59 | 0.113 | 28 | 2 | 0.071 | 8 |
PSAPL1 | PSAPL1 | Q6NUJ1 | Proactivator polypeptide-like 1 | chr4 | GO:0040007 | Not Cancer Driver | No | 62 | 0.119 | 7 | 1 | 0.143 | 0 |
PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0040007 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0040007 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0040007 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0040007 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
PTPN12 | PTPN12 | Q05209 | Tyrosine-protein phosphatase non-receptor type 12 | chr7 | GO:0040007 | Not Cancer Driver | No | 102 | 0.131 | 516 | 60 | 0.116 | 0 |
PTX3 | PTX3 | P26022 | Pentraxin-related protein PTX3 | chr3 | GO:0040007 | Not Cancer Driver | No | 39 | 0.102 | 74 | 2 | 0.027 | 0 |
RAD51B_ENST00000487270 | RAD51B | O15315 | DNA repair protein RAD51 homolog 2 | chr14 | GO:0040007 | Census | Yes | 45 | 0.117 | 13 | 0 | 0.0 | 0 |
RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0040007 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
RARG | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0040007 | Not Cancer Driver | No | 82 | 0.181 | 164 | 24 | 0.146 | 0 |
RBBP6 | RBBP6 | Q7Z6E9 | E3 ubiquitin-protein ligase RBBP6 | chr16 | GO:0040007 | Not Cancer Driver | No | 229 | 0.128 | 1626 | 212 | 0.13 | 0 |
RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:0040007 | Not Cancer Driver | No | 128 | 0.107 | 703 | 81 | 0.115 | 0 |
RDH10 | RDH10 | Q8IZV5 | Retinol dehydrogenase 10 | chr8 | GO:0040007 | Not Cancer Driver | No | 33 | 0.097 | 8 | 0 | 0.0 | 0 |
RMI1 | RMI1 | Q9H9A7 | RecQ-mediated genome instability protein 1 | chr9 | GO:0040007 | Not Cancer Driver | No | 67 | 0.107 | 243 | 26 | 0.107 | 0 |
RSPO2 | RSPO2 | Q6UXX9 | R-spondin-2 | chr8 | GO:0040007 | Census | Yes | 96 | 0.395 | 41 | 10 | 0.244 | 1 |
RTF1 | RTF1 | Q92541 | RNA polymerase-associated protein RTF1 homolog | chr15 | GO:0040007 | Not Cancer Driver | No | 83 | 0.117 | 568 | 67 | 0.118 | 0 |
RUNX1_ENST00000344691 | RUNX1 | Q01196 | Runt-related transcription factor 1 | chr21 | GO:0040007 | Census, Compendium | Yes | 81 | 0.179 | 360 | 58 | 0.161 | 2 |
S1PR1 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | GO:0040007 | Not Cancer Driver | No | 86 | 0.225 | 29 | 6 | 0.207 | 0 |
SALL1 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | GO:0040007 | Not Cancer Driver | No | 454 | 0.343 | 949 | 334 | 0.352 | 0 |
SCNN1B | SCNN1B | P51168 | Amiloride-sensitive sodium channel subunit beta | chr16 | GO:0040007 | Not Cancer Driver | No | 90 | 0.141 | 62 | 4 | 0.065 | 13 |
SELENOM_ENST00000611680 | SELENOM | Q8WWX9 | Selenoprotein M | chr22 | GO:0040007 | Not Cancer Driver | No | 10 | 0.069 | 21 | 2 | 0.095 | 0 |
SEMA3A | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0040007 | Not Cancer Driver | No | 195 | 0.253 | 164 | 46 | 0.28 | 10 |
SEMA3F | SEMA3F | Q13275 | Semaphorin-3F | chr3 | GO:0040007 | Not Cancer Driver | No | 114 | 0.145 | 194 | 27 | 0.139 | 0 |
SGCA | SGCA | Q16586 | Alpha-sarcoglycan | chr17 | GO:0040007 | Not Cancer Driver | No | 58 | 0.15 | 82 | 9 | 0.11 | 29 |
SH3GL2 | SH3GL2 | Q99962 | Endophilin-A1 | chr9 | GO:0040007 | Not Cancer Driver | No | 76 | 0.216 | 214 | 50 | 0.234 | 0 |
SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0040007 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
SLC12A5 | SLC12A5 | Q9H2X9 | Solute carrier family 12 member 5 | chr20 | GO:0040007 | Not Cancer Driver | No | 263 | 0.231 | 290 | 59 | 0.203 | 5 |
SLC1A2 | SLC1A2 | P43004 | Excitatory amino acid transporter 2 | chr11 | GO:0040007 | Not Cancer Driver | No | 77 | 0.134 | 81 | 7 | 0.086 | 3 |
SLC25A25_ENST00000373064 | SLC25A25 | Q6KCM7 | Calcium-binding mitochondrial carrier protein SCaMC-2 | chr9 | GO:0040007 | Not Cancer Driver | No | 45 | 0.096 | 5 | 1 | 0.2 | 0 |
SLC4A10 | SLC4A10 | Q6U841 | Sodium-driven chloride bicarbonate exchanger | chr2 | GO:0040007 | Not Cancer Driver | No | 221 | 0.198 | 340 | 68 | 0.2 | 0 |
SLC9A6_ENST00000370698 | SLC9A6 | Q92581 | Sodium/hydrogen exchanger 6 | chrX | GO:0040007 | Not Cancer Driver | No | 98 | 0.146 | 109 | 19 | 0.174 | 1 |
SLIT1 | SLIT1 | O75093 | Slit homolog 1 protein | chr10 | GO:0040007 | Not Cancer Driver | No | 221 | 0.144 | 36 | 1 | 0.028 | 0 |
SLIT2 | SLIT2 | O94813 | Slit homolog 2 protein | chr4 | GO:0040007 | Not Cancer Driver | No | 428 | 0.28 | 31 | 13 | 0.419 | 0 |
SLIT3_ENST00000519560 | SLIT3 | O75094 | Slit homolog 3 protein | chr5 | GO:0040007 | Not Cancer Driver | No | 351 | 0.23 | 40 | 9 | 0.225 | 0 |
SLITRK1 | SLITRK1 | Q96PX8 | SLIT and NTRK-like protein 1 | chr13 | GO:0040007 | Not Cancer Driver | No | 299 | 0.43 | 126 | 64 | 0.508 | 0 |
SLITRK6_ENST00000643778 | SLITRK6 | Q9H5Y7 | SLIT and NTRK-like protein 6 | chr13 | GO:0040007 | Not Cancer Driver | No | 244 | 0.29 | 225 | 53 | 0.236 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0040007 | Census, Compendium | Yes | 79 | 0.169 | 137 | 12 | 0.088 | 0 |
SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0040007 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0040007 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
SORBS2_ENST00000284776 | SORBS2 | O94875 | Sorbin and SH3 domain-containing protein 2 | chr4 | GO:0040007 | Not Cancer Driver | No | 172 | 0.156 | 854 | 137 | 0.16 | 0 |
SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0040007 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
SOX15_ENST00000538513 | SOX15 | O60248 | Protein SOX-15 | chr17 | GO:0040007 | Not Cancer Driver | No | 18 | 0.077 | 227 | 18 | 0.079 | 0 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | GO:0040007 | Census | Yes | 39 | 0.123 | 312 | 39 | 0.125 | 0 |
SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0040007 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
SP2 | SP2 | Q02086 | Transcription factor Sp2 | chr17 | GO:0040007 | Not Cancer Driver | No | 59 | 0.096 | 503 | 55 | 0.109 | 0 |
SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0040007 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0040007 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
SPTBN2 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | GO:0040007 | Not Cancer Driver | No | 317 | 0.133 | 877 | 126 | 0.144 | 2 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0040007 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
STIL_ENST00000360380 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | GO:0040007 | Census, Compendium | Yes | 147 | 0.114 | 735 | 85 | 0.116 | 1 |
STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0040007 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
STK40_ENST00000373132 | STK40 | Q8N2I9 | Serine/threonine-protein kinase 40 | chr1 | GO:0040007 | Not Cancer Driver | No | 50 | 0.115 | 103 | 9 | 0.087 | 0 |
TAF10 | TAF10 | Q12962 | Transcription initiation factor TFIID subunit 10 | chr11 | GO:0040007 | Not Cancer Driver | No | 17 | 0.078 | 131 | 4 | 0.031 | 0 |
TAL2 | TAL2 | Q16559 | T-cell acute lymphocytic leukemia protein 2 | chr9 | GO:0040007 | Census | Yes | 18 | 0.167 | 81 | 14 | 0.173 | 0 |
TARBP2 | TARBP2 | Q15633 | RISC-loading complex subunit TARBP2 | chr12 | GO:0040007 | Not Cancer Driver | No | 45 | 0.123 | 203 | 22 | 0.108 | 0 |
TBL1XR1 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0040007 | Census, Compendium | Yes | 82 | 0.16 | 136 | 19 | 0.14 | 4 |
TEC | TEC | P42680 | Tyrosine-protein kinase Tec | chr4 | GO:0040007 | Census, Compendium | Yes | 91 | 0.144 | 57 | 15 | 0.263 | 0 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0040007 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
TM4SF4 | TM4SF4 | P48230 | Transmembrane 4 L6 family member 4 | chr3 | GO:0040007 | Not Cancer Driver | No | 36 | 0.178 | 0 | 0 | 0.0 | 0 |
TMED2 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | GO:0040007 | Not Cancer Driver | No | 24 | 0.119 | 25 | 4 | 0.16 | 0 |
TMEM108 | TMEM108 | Q6UXF1 | Transmembrane protein 108 | chr3 | GO:0040007 | Not Cancer Driver | No | 101 | 0.176 | 458 | 89 | 0.194 | 0 |
TNFAIP6 | TNFAIP6 | P98066 | Tumor necrosis factor-inducible gene 6 protein | chr2 | GO:0040007 | Not Cancer Driver | No | 62 | 0.224 | 13 | 5 | 0.385 | 0 |
TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:0040007 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
TNS2_ENST00000314250 | TNS2 | Q63HR2 | Tensin-2 | chr12 | GO:0040007 | Not Cancer Driver | No | 132 | 0.094 | 799 | 63 | 0.079 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0040007 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
TSKU_ENST00000333090 | TSKU | Q8WUA8 | Tsukushi | chr11 | GO:0040007 | Not Cancer Driver | No | 53 | 0.15 | 44 | 6 | 0.136 | 0 |
TTC8_ENST00000338104 | TTC8 | Q8TAM2 | Tetratricopeptide repeat protein 8 | chr14 | GO:0040007 | Not Cancer Driver | No | 74 | 0.137 | 98 | 12 | 0.122 | 0 |
TXK | TXK | P42681 | Tyrosine-protein kinase TXK | chr4 | GO:0040007 | Not Cancer Driver | No | 87 | 0.165 | 61 | 9 | 0.148 | 0 |
UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0040007 | Not Cancer Driver | No | 141 | 0.161 | 136 | 22 | 0.162 | 0 |
UBTFL1 | UBTFL1 | P0CB47 | Upstream-binding factor 1-like protein 1 | chr11 | GO:0040007 | Not Cancer Driver | No | 13 | 0.033 | 257 | 9 | 0.035 | 0 |
WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | GO:0040007 | Not Cancer Driver | No | 63 | 0.113 | 445 | 49 | 0.11 | 0 |
WDR11 | WDR11 | Q9BZH6 | WD repeat-containing protein 11 | chr10 | GO:0040007 | Not Cancer Driver | No | 122 | 0.1 | 94 | 6 | 0.064 | 6 |
WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0040007 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
WDTC1 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | GO:0040007 | Not Cancer Driver | No | 81 | 0.12 | 154 | 21 | 0.136 | 0 |
WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0040007 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
WWTR1_ENST00000360632 | WWTR1 | Q9GZV5 | WW domain-containing transcription regulator protein 1 | chr3 | GO:0040007 | Census | Yes | 41 | 0.102 | 387 | 41 | 0.106 | 0 |
XRCC2 | XRCC2 | O43543 | DNA repair protein XRCC2 | chr7 | GO:0040007 | Not Cancer Driver | No | 36 | 0.129 | 9 | 1 | 0.111 | 2 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0040007 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |
ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0040007 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |
ZFY_ENST00000155093 | ZFY | P08048 | Zinc finger Y-chromosomal protein | chrY | GO:0040007 | Not Cancer Driver | No | 29 | 0.036 | 357 | 8 | 0.022 | 0 |
ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0040007 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
ZNF830 | ZNF830 | Q96NB3 | Zinc finger protein 830 | chr17 | GO:0040007 | Not Cancer Driver | No | 39 | 0.105 | 312 | 37 | 0.119 | 0 |