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Total number of protein in "GO:0035725" GO term:  120

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0035725 Not Cancer Driver No 134 0.147 80 11 0.138 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0035725 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0035725 Not Cancer Driver No 101 0.197 49 1 0.02 0
ASIC3_ENST00000349064 ASIC3 Q9UHC3 Acid-sensing ion channel 3 chr7 GO:0035725 Not Cancer Driver No 83 0.156 126 23 0.183 0
ASIC5 ASIC5 Q9NY37 Acid-sensing ion channel 5 chr4 GO:0035725 Not Cancer Driver No 112 0.222 12 4 0.333 0
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 GO:0035725 Not Cancer Driver No 203 0.195 117 24 0.205 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0035725 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0035725 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0035725 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0035725 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0035725 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0035725 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 GO:0035725 Not Cancer Driver No 36 0.129 6 1 0.167 0
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 GO:0035725 Not Cancer Driver No 201 0.194 121 30 0.248 0
ATP4B ATP4B P51164 Potassium-transporting ATPase subunit beta chr13 GO:0035725 Not Cancer Driver No 35 0.12 2 0 0.0 0
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0035725 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0035725 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CACNA1I CACNA1I Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I chr22 GO:0035725 Not Cancer Driver No 272 0.122 870 73 0.084 0
CNNM4 CNNM4 Q6P4Q7 Metal transporter CNNM4 chr2 GO:0035725 Not Cancer Driver No 104 0.134 116 22 0.19 4
FXYD2 FXYD2 P54710 Sodium/potassium-transporting ATPase subunit gamma chr11 GO:0035725 Not Cancer Driver No 2 0.03 20 2 0.1 1
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0035725 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0035725 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0035725 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0035725 Not Cancer Driver No 187 0.155 631 58 0.092 3
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 GO:0035725 Not Cancer Driver No 65 0.193 21 4 0.19 0
NALCN NALCN Q8IZF0 Sodium leak channel NALCN chr13 GO:0035725 Not Cancer Driver No 499 0.287 260 74 0.285 11
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0035725 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKD2L1 PKD2L1 Q9P0L9 Polycystic kidney disease 2-like 1 protein chr10 GO:0035725 Not Cancer Driver No 135 0.168 180 32 0.178 0
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0035725 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0035725 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0035725 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0035725 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0035725 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0035725 Not Cancer Driver No 46 0.214 52 7 0.135 2
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 GO:0035725 Not Cancer Driver No 415 0.207 432 83 0.192 6
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0035725 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 GO:0035725 Not Cancer Driver No 324 0.176 372 80 0.215 60
SCN4B SCN4B Q8IWT1 Sodium channel subunit beta-4 chr11 GO:0035725 Not Cancer Driver No 23 0.101 46 4 0.087 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0035725 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0035725 Not Cancer Driver No 395 0.235 171 43 0.251 0
SCN8A SCN8A Q9UQD0 Sodium channel protein type 8 subunit alpha chr12 GO:0035725 Not Cancer Driver No 290 0.146 460 75 0.163 28
SCN9A_ENST00000642356 SCN9A Q15858 Sodium channel protein type 9 subunit alpha chr2 GO:0035725 Not Cancer Driver No 461 0.232 490 126 0.257 21
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0035725 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0035725 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0035725 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0035725 Not Cancer Driver No 129 0.199 57 11 0.193 0
SHROOM2 SHROOM2 Q13796 Protein Shroom2 chrX GO:0035725 Not Cancer Driver No 215 0.133 1381 188 0.136 0
SLC12A1_ENST00000380993 SLC12A1 Q13621 Solute carrier family 12 member 1 chr15 GO:0035725 Not Cancer Driver No 199 0.181 143 35 0.245 2
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0035725 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A3_ENST00000563236 SLC12A3 P55017 Solute carrier family 12 member 3 chr16 GO:0035725 Not Cancer Driver No 146 0.143 124 16 0.129 117
SLC17A1_ENST00000476801 SLC17A1 Q14916 Sodium-dependent phosphate transport protein 1 chr6 GO:0035725 Not Cancer Driver No 84 0.18 7 2 0.286 0
SLC17A2_ENST00000265425 SLC17A2 O00624 Sodium-dependent phosphate transport protein 3 chr6 GO:0035725 Not Cancer Driver No 81 0.185 12 5 0.417 0
SLC17A3_ENST00000360657 SLC17A3 O00476 Sodium-dependent phosphate transport protein 4 chr6 GO:0035725 Not Cancer Driver No 97 0.231 26 6 0.231 0
SLC17A4 SLC17A4 Q9Y2C5 Probable small intestine urate exporter chr6 GO:0035725 Not Cancer Driver No 108 0.217 44 9 0.205 0
SLC17A7 SLC17A7 Q9P2U7 Vesicular glutamate transporter 1 chr19 GO:0035725 Not Cancer Driver No 79 0.141 80 21 0.263 0
SLC20A1 SLC20A1 Q8WUM9 Sodium-dependent phosphate transporter 1 chr2 GO:0035725 Not Cancer Driver No 67 0.099 157 9 0.057 0
SLC20A2_ENST00000520179 SLC20A2 Q08357 Sodium-dependent phosphate transporter 2 chr8 GO:0035725 Not Cancer Driver No 97 0.149 149 26 0.174 17
SLC23A1_ENST00000348729 SLC23A1 Q9UHI7 Solute carrier family 23 member 1 chr5 GO:0035725 Not Cancer Driver No 74 0.124 47 5 0.106 0
SLC24A1 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0035725 Not Cancer Driver No 105 0.096 595 53 0.089 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0035725 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A3 SLC24A3 Q9HC58 Sodium/potassium/calcium exchanger 3 chr20 GO:0035725 Not Cancer Driver No 143 0.222 120 45 0.375 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0035725 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC24A5 SLC24A5 Q71RS6 Sodium/potassium/calcium exchanger 5 chr15 GO:0035725 Not Cancer Driver No 79 0.158 7 2 0.286 0
SLC28A3 SLC28A3 Q9HAS3 Solute carrier family 28 member 3 chr9 GO:0035725 Not Cancer Driver No 104 0.151 83 9 0.108 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0035725 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC34A2 SLC34A2 O95436 Sodium-dependent phosphate transport protein 2B chr4 GO:0035725 Census Yes 132 0.191 65 15 0.231 1
SLC34A3_ENST00000361134 SLC34A3 Q8N130 Sodium-dependent phosphate transport protein 2C chr9 GO:0035725 Not Cancer Driver No 56 0.093 63 9 0.143 6
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 GO:0035725 Not Cancer Driver No 62 0.098 171 12 0.07 0
SLC41A1 SLC41A1 Q8IVJ1 Solute carrier family 41 member 1 chr1 GO:0035725 Not Cancer Driver No 68 0.133 103 15 0.146 1
SLC4A10 SLC4A10 Q6U841 Sodium-driven chloride bicarbonate exchanger chr2 GO:0035725 Not Cancer Driver No 221 0.198 340 68 0.2 0
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0035725 Not Cancer Driver No 159 0.182 69 10 0.145 42
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0035725 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLC4A5_ENST00000377634 SLC4A5 Q9BY07 Electrogenic sodium bicarbonate cotransporter 4 chr2 GO:0035725 Not Cancer Driver No 167 0.147 353 46 0.13 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 GO:0035725 Not Cancer Driver No 165 0.136 406 57 0.14 0
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0035725 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC4A9 SLC4A9 Q96Q91 Anion exchange protein 4 chr5 GO:0035725 Not Cancer Driver No 98 0.1 208 20 0.096 0
SLC5A1 SLC5A1 P13866 Sodium/glucose cotransporter 1 chr22 GO:0035725 Not Cancer Driver No 104 0.157 47 2 0.043 22
SLC5A10_ENST00000395645 SLC5A10 A0PJK1 Sodium/glucose cotransporter 5 chr17 GO:0035725 Not Cancer Driver No 79 0.133 2 0 0.0 0
SLC5A2 SLC5A2 P31639 Sodium/glucose cotransporter 2 chr16 GO:0035725 Not Cancer Driver No 91 0.135 61 4 0.066 1
SLC6A11 SLC6A11 P48066 Sodium- and chloride-dependent GABA transporter 3 chr3 GO:0035725 Not Cancer Driver No 116 0.184 39 2 0.051 0
SLC6A12_ENST00000536824 SLC6A12 P48065 Sodium- and chloride-dependent betaine transporter chr12 GO:0035725 Not Cancer Driver No 94 0.153 45 8 0.178 0
SLC6A13 SLC6A13 Q9NSD5 Sodium- and chloride-dependent GABA transporter 2 chr12 GO:0035725 Not Cancer Driver No 136 0.226 37 11 0.297 0
SLC6A14 SLC6A14 Q9UN76 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) chrX GO:0035725 Not Cancer Driver No 116 0.181 27 3 0.111 0
SLC6A15 SLC6A15 Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 chr12 GO:0035725 Not Cancer Driver No 163 0.223 70 22 0.314 0
SLC6A16 SLC6A16 Q9GZN6 Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 chr19 GO:0035725 Not Cancer Driver No 95 0.129 73 8 0.11 0
SLC6A17 SLC6A17 Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 GO:0035725 Not Cancer Driver No 119 0.164 67 10 0.149 2
SLC6A18 SLC6A18 Q96N87 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 chr5 GO:0035725 Not Cancer Driver No 122 0.194 37 5 0.135 0
SLC6A19 SLC6A19 Q695T7 Sodium-dependent neutral amino acid transporter B(0)AT1 chr5 GO:0035725 Not Cancer Driver No 130 0.205 1 0 0.0 14
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0035725 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A20 SLC6A20 Q9NP91 Sodium- and chloride-dependent transporter XTRP3 chr3 GO:0035725 Not Cancer Driver No 81 0.137 0 0 0.0 0
SLC6A2_ENST00000568943 SLC6A2 P23975 Sodium-dependent noradrenaline transporter chr16 GO:0035725 Not Cancer Driver No 127 0.206 23 8 0.348 1
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0035725 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0035725 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC6A5 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 chr11 GO:0035725 Not Cancer Driver No 181 0.227 169 38 0.225 7
SLC6A6_ENST00000622186 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 GO:0035725 Not Cancer Driver No 80 0.129 22 1 0.045 2
SLC6A7 SLC6A7 Q99884 Sodium-dependent proline transporter chr5 GO:0035725 Not Cancer Driver No 80 0.126 19 3 0.158 0
SLC6A8 SLC6A8 P48029 Sodium- and chloride-dependent creatine transporter 1 chrX GO:0035725 Not Cancer Driver No 50 0.079 25 1 0.04 12
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0035725 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0035725 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0035725 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0035725 Not Cancer Driver No 263 0.284 152 35 0.23 0
SLC8B1 SLC8B1 Q6J4K2 Mitochondrial sodium/calcium exchanger protein chr12 GO:0035725 Not Cancer Driver No 70 0.12 0 0 0.0 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0035725 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A2 SLC9A2 Q9UBY0 Sodium/hydrogen exchanger 2 chr2 GO:0035725 Not Cancer Driver No 165 0.203 221 63 0.285 0
SLC9A3 SLC9A3 P48764 Sodium/hydrogen exchanger 3 chr5 GO:0035725 Not Cancer Driver No 105 0.126 225 30 0.133 3
SLC9A4 SLC9A4 Q6AI14 Sodium/hydrogen exchanger 4 chr2 GO:0035725 Not Cancer Driver No 197 0.247 197 77 0.391 0
SLC9A5 SLC9A5 Q14940 Sodium/hydrogen exchanger 5 chr16 GO:0035725 Not Cancer Driver No 118 0.132 307 35 0.114 0
SLC9A6_ENST00000370698 SLC9A6 Q92581 Sodium/hydrogen exchanger 6 chrX GO:0035725 Not Cancer Driver No 98 0.146 109 19 0.174 1
SLC9A7_ENST00000328306 SLC9A7 Q96T83 Sodium/hydrogen exchanger 7 chrX GO:0035725 Not Cancer Driver No 102 0.141 180 29 0.161 1
SLC9A8_ENST00000361573 SLC9A8 Q9Y2E8 Sodium/hydrogen exchanger 8 chr20 GO:0035725 Not Cancer Driver No 73 0.126 75 8 0.107 0
SLC9A9 SLC9A9 Q8IVB4 Sodium/hydrogen exchanger 9 chr3 GO:0035725 Not Cancer Driver No 133 0.206 100 14 0.14 0
SLC9B1 SLC9B1 Q4ZJI4 Sodium/hydrogen exchanger 9B1 chr4 GO:0035725 Not Cancer Driver No 89 0.173 48 6 0.125 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0035725 Not Cancer Driver No 68 0.127 80 16 0.2 0
SLC9C1 SLC9C1 Q4G0N8 Sodium/hydrogen exchanger 10 chr3 GO:0035725 Not Cancer Driver No 214 0.182 44 9 0.205 0
SLC9C2 SLC9C2 Q5TAH2 Sodium/hydrogen exchanger 11 chr1 GO:0035725 Not Cancer Driver No 283 0.252 26 3 0.115 0
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 GO:0035725 Not Cancer Driver No 114 0.14 99 18 0.182 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 GO:0035725 Not Cancer Driver No 73 0.097 16 0 0.0 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0035725 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0035725 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPM5 TRPM5 Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 chr11 GO:0035725 Not Cancer Driver No 123 0.106 186 19 0.102 0