Total number of protein in "GO:0035591" GO term: 79
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0035591 | Census, Compendium | Yes | 55 | 0.108 | 360 | 39 | 0.108 | 0 |
| ABI2_ENST00000261018 | ABI2 | Q9NYB9 | Abl interactor 2 | chr2 | GO:0035591 | Not Cancer Driver | No | 56 | 0.109 | 361 | 38 | 0.105 | 0 |
| AFAP1L2 | AFAP1L2 | Q8N4X5 | Actin filament-associated protein 1-like 2 | chr10 | GO:0035591 | Not Cancer Driver | No | 86 | 0.105 | 558 | 59 | 0.106 | 0 |
| AKAP13_ENST00000394518 | AKAP13 | Q12802 | A-kinase anchor protein 13 | chr15 | GO:0035591 | Not Cancer Driver | No | 359 | 0.128 | 2091 | 258 | 0.123 | 0 |
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0035591 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BANK1 | BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | chr4 | GO:0035591 | Not Cancer Driver | No | 150 | 0.191 | 394 | 73 | 0.185 | 0 |
| BLNK | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:0035591 | Not Cancer Driver | No | 74 | 0.162 | 376 | 61 | 0.162 | 0 |
| CARD10_ENST00000251973 | CARD10 | Q9BWT7 | Caspase recruitment domain-containing protein 10 | chr22 | GO:0035591 | Not Cancer Driver | No | 94 | 0.091 | 474 | 40 | 0.084 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0035591 | Not Cancer Driver | No | 28 | 0.135 | 72 | 12 | 0.167 | 0 |
| CD3G | CD3G | P09693 | T-cell surface glycoprotein CD3 gamma chain | chr11 | GO:0035591 | Not Cancer Driver | No | 25 | 0.137 | 48 | 7 | 0.146 | 0 |
| CDC42SE2 | CDC42SE2 | Q9NRR3 | CDC42 small effector protein 2 | chr5 | GO:0035591 | Not Cancer Driver | No | 1 | 0.012 | 57 | 1 | 0.018 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0035591 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0035591 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0035591 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DEDD2 | DEDD2 | Q8WXF8 | DNA-binding death effector domain-containing protein 2 | chr19 | GO:0035591 | Not Cancer Driver | No | 42 | 0.129 | 133 | 25 | 0.188 | 0 |
| DLG5 | DLG5 | Q8TDM6 | Disks large homolog 5 | chr10 | GO:0035591 | Not Cancer Driver | No | 230 | 0.12 | 1119 | 135 | 0.121 | 0 |
| DOK2 | DOK2 | O60496 | Docking protein 2 | chr8 | GO:0035591 | Not Cancer Driver | No | 58 | 0.141 | 254 | 31 | 0.122 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0035591 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
| EPS8_ENST00000645775 | EPS8 | Q12929 | Epidermal growth factor receptor kinase substrate 8 | chr12 | GO:0035591 | Not Cancer Driver | No | 106 | 0.129 | 459 | 54 | 0.118 | 0 |
| FCRL2 | FCRL2 | Q96LA5 | Fc receptor-like protein 2 | chr1 | GO:0035591 | Not Cancer Driver | No | 116 | 0.228 | 76 | 14 | 0.184 | 0 |
| FRS2 | FRS2 | Q8WU20 | Fibroblast growth factor receptor substrate 2 | chr12 | GO:0035591 | Not Cancer Driver | No | 69 | 0.136 | 415 | 58 | 0.14 | 0 |
| FRS3_ENST00000259748 | FRS3 | O43559 | Fibroblast growth factor receptor substrate 3 | chr6 | GO:0035591 | Not Cancer Driver | No | 77 | 0.157 | 388 | 58 | 0.149 | 0 |
| G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | GO:0035591 | Not Cancer Driver | No | 64 | 0.133 | 384 | 53 | 0.138 | 0 |
| GAB2 | GAB2 | Q9UQC2 | GRB2-associated-binding protein 2 | chr11 | GO:0035591 | Not Cancer Driver | No | 85 | 0.126 | 537 | 73 | 0.136 | 0 |
| GNB1_ENST00000378609 | GNB1 | P62873 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | chr1 | GO:0035591 | Not Cancer Driver | No | 45 | 0.132 | 24 | 2 | 0.083 | 16 |
| GNB2 | GNB2 | P62879 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | chr7 | GO:0035591 | Not Cancer Driver | No | 50 | 0.147 | 21 | 0 | 0.0 | 7 |
| GNB3 | GNB3 | P16520 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | chr12 | GO:0035591 | Not Cancer Driver | No | 51 | 0.15 | 13 | 1 | 0.077 | 0 |
| GNB4_ENST00000468623 | GNB4 | Q9HAV0 | Guanine nucleotide-binding protein subunit beta-4 | chr3 | GO:0035591 | Not Cancer Driver | No | 49 | 0.144 | 27 | 3 | 0.111 | 2 |
| GNB5 | GNB5 | O14775 | Guanine nucleotide-binding protein subunit beta-5 | chr15 | GO:0035591 | Not Cancer Driver | No | 60 | 0.152 | 16 | 1 | 0.062 | 1 |
| GRAPL | GRAPL | Q8TC17 | GRB2-related adapter protein-like | chr17 | GO:0035591 | Not Cancer Driver | No | 0 | 0.0 | 26 | 0 | 0.0 | 0 |
| GRB10_ENST00000401949 | GRB10 | Q13322 | Growth factor receptor-bound protein 10 | chr7 | GO:0035591 | Not Cancer Driver | No | 94 | 0.158 | 220 | 38 | 0.173 | 0 |
| GRIP1_ENST00000359742 | GRIP1 | Q9Y3R0 | Glutamate receptor-interacting protein 1 | chr12 | GO:0035591 | Not Cancer Driver | No | 203 | 0.18 | 568 | 101 | 0.178 | 0 |
| GRIP2_ENST00000621039 | GRIP2 | Q9C0E4 | Glutamate receptor-interacting protein 2 | chr3 | GO:0035591 | Not Cancer Driver | No | 143 | 0.137 | 586 | 84 | 0.143 | 0 |
| HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | GO:0035591 | Not Cancer Driver | No | 46 | 0.13 | 243 | 32 | 0.132 | 0 |
| HOMER2 | HOMER2 | Q9NSB8 | Homer protein homolog 2 | chr15 | GO:0035591 | Not Cancer Driver | No | 53 | 0.15 | 233 | 32 | 0.137 | 1 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0035591 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0035591 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| KHDRBS1 | KHDRBS1 | Q07666 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | chr1 | GO:0035591 | Not Cancer Driver | No | 53 | 0.12 | 362 | 43 | 0.119 | 0 |
| KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | GO:0035591 | Not Cancer Driver | No | 114 | 0.124 | 404 | 58 | 0.144 | 0 |
| LAT_ENST00000360872 | LAT | O43561 | Linker for activation of T-cells family member 1 | chr16 | GO:0035591 | Not Cancer Driver | No | 37 | 0.141 | 213 | 29 | 0.136 | 0 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0035591 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0035591 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MAGI2 | MAGI2 | Q86UL8 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | chr7 | GO:0035591 | Not Cancer Driver | No | 305 | 0.21 | 1086 | 201 | 0.185 | 0 |
| MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | GO:0035591 | Census, Compendium | Yes | 94 | 0.239 | 96 | 24 | 0.25 | 6 |
| MAP2K2 | MAP2K2 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2 | chr19 | GO:0035591 | Census | Yes | 58 | 0.145 | 105 | 14 | 0.133 | 4 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0035591 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MAPK8IP2 | MAPK8IP2 | Q13387 | C-Jun-amino-terminal kinase-interacting protein 2 | chr22 | GO:0035591 | Not Cancer Driver | No | 49 | 0.059 | 568 | 27 | 0.048 | 0 |
| MAPK8IP3_ENST00000250894 | MAPK8IP3 | Q9UPT6 | C-Jun-amino-terminal kinase-interacting protein 3 | chr16 | GO:0035591 | Not Cancer Driver | No | 179 | 0.134 | 746 | 110 | 0.147 | 3 |
| MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | GO:0035591 | Not Cancer Driver | No | 70 | 0.13 | 411 | 58 | 0.141 | 0 |
| MMS19 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:0035591 | Not Cancer Driver | No | 73 | 0.071 | 11 | 0 | 0.0 | 0 |
| MPP7 | MPP7 | Q5T2T1 | MAGUK p55 subfamily member 7 | chr10 | GO:0035591 | Not Cancer Driver | No | 132 | 0.229 | 199 | 72 | 0.362 | 0 |
| NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0035591 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0035591 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0035591 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
| PAG1 | PAG1 | Q9NWQ8 | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | chr8 | GO:0035591 | Not Cancer Driver | No | 58 | 0.134 | 394 | 54 | 0.137 | 0 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0035591 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0035591 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0035591 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0035591 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
| ROPN1B_ENST00000251776 | ROPN1B | Q9BZX4 | Ropporin-1B | chr3 | GO:0035591 | Not Cancer Driver | No | 35 | 0.165 | 15 | 1 | 0.067 | 0 |
| SARM1 | SARM1 | Q6SZW1 | NAD(+) hydrolase SARM1 | chr17 | GO:0035591 | Not Cancer Driver | No | 36 | 0.05 | 80 | 4 | 0.05 | 0 |
| SAV1 | SAV1 | Q9H4B6 | Protein salvador homolog 1 | chr14 | GO:0035591 | Not Cancer Driver | No | 42 | 0.11 | 243 | 17 | 0.07 | 0 |
| SH2B1 | SH2B1 | Q9NRF2 | SH2B adapter protein 1 | chr16 | GO:0035591 | Not Cancer Driver | No | 98 | 0.13 | 612 | 84 | 0.137 | 0 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0035591 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0035591 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SHANK1 | SHANK1 | Q9Y566 | SH3 and multiple ankyrin repeat domains protein 1 | chr19 | GO:0035591 | Not Cancer Driver | No | 288 | 0.133 | 1659 | 186 | 0.112 | 0 |
| SHANK2_ENST00000601538 | SHANK2 | Q9UPX8 | SH3 and multiple ankyrin repeat domains protein 2 | chr11 | GO:0035591 | Not Cancer Driver | No | 303 | 0.164 | 1379 | 262 | 0.19 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0035591 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SLA2 | SLA2 | Q9H6Q3 | Src-like-adapter 2 | chr20 | GO:0035591 | Not Cancer Driver | No | 32 | 0.123 | 43 | 9 | 0.209 | 0 |
| SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0035591 | Not Cancer Driver | No | 32 | 0.162 | 61 | 2 | 0.033 | 0 |
| SORBS1_ENST00000361941 | SORBS1 | Q9BX66 | Sorbin and SH3 domain-containing protein 1 | chr10 | GO:0035591 | Not Cancer Driver | No | 161 | 0.125 | 1111 | 133 | 0.12 | 0 |
| SPAG9 | SPAG9 | O60271 | C-Jun-amino-terminal kinase-interacting protein 4 | chr17 | GO:0035591 | Not Cancer Driver | No | 128 | 0.097 | 841 | 81 | 0.096 | 0 |
| SPATA2_ENST00000289431 | SPATA2 | Q9UM82 | Spermatogenesis-associated protein 2 | chr20 | GO:0035591 | Not Cancer Driver | No | 70 | 0.135 | 235 | 39 | 0.166 | 0 |
| STAP1_ENST00000396225 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:0035591 | Not Cancer Driver | No | 66 | 0.224 | 103 | 18 | 0.175 | 0 |
| STAP2_ENST00000594605 | STAP2 | Q9UGK3 | Signal-transducing adaptor protein 2 | chr19 | GO:0035591 | Not Cancer Driver | No | 43 | 0.107 | 177 | 16 | 0.09 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0035591 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0035591 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAT1 | TRAT1 | Q6PIZ9 | T-cell receptor-associated transmembrane adapter 1 | chr3 | GO:0035591 | Not Cancer Driver | No | 86 | 0.462 | 129 | 67 | 0.519 | 0 |
| ZDHHC11 | ZDHHC11 | Q9H8X9 | Palmitoyltransferase ZDHHC11 | chr5 | GO:0035591 | Not Cancer Driver | No | 68 | 0.165 | 76 | 24 | 0.316 | 0 |