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Total number of protein in "GO:0035239" GO term:  217

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0035239 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0035239 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAMTS16 ADAMTS16 Q8TE57 A disintegrin and metalloproteinase with thrombospondin motifs 16 chr5 GO:0035239 Not Cancer Driver No 383 0.313 179 59 0.33 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0035239 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0035239 Not Cancer Driver No 255 0.189 53 11 0.208 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0035239 Not Cancer Driver No 23 0.131 20 2 0.1 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0035239 Not Cancer Driver No 120 0.1 500 56 0.112 6
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0035239 Not Cancer Driver No 52 0.113 154 26 0.169 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0035239 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOE APOE P02649 Apolipoprotein E chr19 GO:0035239 Not Cancer Driver No 25 0.079 124 6 0.048 12
AREG AREG P15514 Amphiregulin chr4 GO:0035239 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0035239 Census, Compendium Yes 272 0.148 1143 141 0.123 0
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 GO:0035239 Not Cancer Driver No 99 0.138 56 8 0.143 4
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0035239 Census, Compendium Yes 24 0.1 72 5 0.069 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0035239 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0035239 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0035239 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0035239 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0035239 Compendium Yes 141 0.136 601 70 0.116 19
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0035239 Not Cancer Driver No 80 0.132 45 4 0.089 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0035239 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0035239 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCL11 CCL11 P51671 Eotaxin chr17 GO:0035239 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCM2_ENST00000258781 CCM2 Q9BSQ5 Cerebral cavernous malformations 2 protein chr7 GO:0035239 Not Cancer Driver No 58 0.131 132 8 0.061 3
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0035239 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0035239 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0035239 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0035239 Not Cancer Driver No 24 0.095 49 4 0.082 0
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0035239 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0035239 Not Cancer Driver No 97 0.128 306 52 0.17 61
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0035239 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0035239 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSMD1 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0035239 Not Cancer Driver No 1236 0.347 234 76 0.325 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0035239 Not Cancer Driver No 20 0.093 19 0 0.0 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0035239 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0035239 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTSZ CTSZ Q9UBR2 Cathepsin Z chr20 GO:0035239 Not Cancer Driver No 30 0.099 10 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0035239 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0035239 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0035239 Not Cancer Driver No 102 0.114 485 61 0.126 4
DCHS1 DCHS1 Q96JQ0 Protocadherin-16 chr11 GO:0035239 Not Cancer Driver No 444 0.135 2197 317 0.144 3
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0035239 Not Cancer Driver No 123 0.135 253 49 0.194 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0035239 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0035239 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0035239 Not Cancer Driver No 75 0.109 73 15 0.205 7
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0035239 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0035239 Not Cancer Driver No 62 0.145 21 6 0.286 2
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0035239 Not Cancer Driver No 42 0.126 97 15 0.155 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0035239 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0035239 Census, Compendium Yes 444 0.367 223 35 0.157 1
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0035239 Not Cancer Driver No 34 0.135 147 21 0.143 0
ENG ENG P17813 Endoglin chr9 GO:0035239 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0035239 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0035239 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0035239 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0035239 Not Cancer Driver No 155 0.155 137 16 0.117 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0035239 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESRP2_ENST00000565858 ESRP2 Q9H6T0 Epithelial splicing regulatory protein 2 chr16 GO:0035239 Not Cancer Driver No 79 0.109 145 12 0.083 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0035239 Census Yes 107 0.143 58 7 0.121 12
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0035239 Not Cancer Driver No 168 0.284 341 99 0.29 15
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0035239 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0035239 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0035239 Not Cancer Driver No 30 0.129 79 9 0.114 6
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 GO:0035239 Not Cancer Driver No 60 0.103 134 8 0.06 3
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0035239 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0035239 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0035239 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0035239 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0035239 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0035239 Not Cancer Driver No 47 0.129 215 25 0.116 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0035239 Not Cancer Driver No 57 0.106 33 5 0.152 19
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0035239 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0035239 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 GO:0035239 Not Cancer Driver No 43 0.124 243 31 0.128 0
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0035239 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0035239 Not Cancer Driver No 47 0.223 83 18 0.217 2
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0035239 Not Cancer Driver No 74 0.207 92 21 0.228 5
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0035239 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0035239 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0035239 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0035239 Compendium Yes 52 0.138 32 4 0.125 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0035239 Census Yes 89 0.153 86 11 0.128 1
GREB1L GREB1L Q9C091 GREB1-like protein chr18 GO:0035239 Not Cancer Driver No 87 0.045 480 22 0.046 25
GZF1 GZF1 Q9H116 GDNF-inducible zinc finger protein 1 chr20 GO:0035239 Not Cancer Driver No 94 0.132 312 47 0.151 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0035239 Not Cancer Driver No 47 0.217 124 29 0.234 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0035239 Not Cancer Driver No 173 0.125 974 135 0.139 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0035239 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0035239 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEY1_ENST00000354724 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0035239 Census Yes 33 0.109 172 15 0.087 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0035239 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHIP HHIP Q96QV1 Hedgehog-interacting protein chr4 GO:0035239 Not Cancer Driver No 150 0.214 73 34 0.466 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0035239 Census Yes 118 0.143 435 51 0.117 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0035239 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0035239 Census Yes 37 0.095 171 22 0.129 4
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0035239 Not Cancer Driver No 90 0.269 262 68 0.26 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:0035239 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXD11 HOXD11 P31277 Homeobox protein Hox-D11 chr2 GO:0035239 Census Yes 32 0.095 219 14 0.064 0
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0035239 Not Cancer Driver No 32 0.12 4 1 0.25 2
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0035239 Not Cancer Driver No 14 0.104 52 7 0.135 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0035239 Not Cancer Driver No 58 0.141 111 15 0.135 6
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0035239 Not Cancer Driver No 45 0.1 71 9 0.127 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0035239 Not Cancer Driver No 182 0.149 172 20 0.116 52
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0035239 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0035239 Census, Compendium Yes 357 0.263 275 55 0.2 2
KLHL3 KLHL3 Q9UH77 Kelch-like protein 3 chr5 GO:0035239 Not Cancer Driver No 67 0.114 34 9 0.265 32
KRAS KRAS P01116 GTPase KRas chr12 GO:0035239 Census, Compendium Yes 788 4.169 7 2 0.286 27
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 GO:0035239 Not Cancer Driver No 600 0.195 329 71 0.216 0
LAMA5 LAMA5 O15230 Laminin subunit alpha-5 chr20 GO:0035239 Not Cancer Driver No 431 0.117 701 90 0.128 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0035239 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0035239 Census Yes 64 0.16 370 57 0.154 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0035239 Not Cancer Driver No 108 0.114 16 3 0.188 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0035239 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0035239 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0035239 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP5L_ENST00000402785 LRP5L A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein chr22 GO:0035239 Not Cancer Driver No 38 0.151 39 5 0.128 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 GO:0035239 Not Cancer Driver No 78 0.117 508 66 0.13 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0035239 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0035239 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0035239 Not Cancer Driver No 363 0.128 476 59 0.124 3
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0035239 Not Cancer Driver No 8 0.03 247 7 0.028 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0035239 Census, Compendium Yes 226 0.163 62 15 0.242 19
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 GO:0035239 Not Cancer Driver No 82 0.147 152 23 0.151 2
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0035239 Not Cancer Driver No 64 0.11 118 11 0.093 1
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0035239 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0035239 Not Cancer Driver No 107 0.142 584 86 0.147 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0035239 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0035239 Not Cancer Driver No 284 0.303 853 263 0.308 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0035239 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0035239 Not Cancer Driver No 155 0.172 685 120 0.175 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0035239 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0035239 Not Cancer Driver No 35 0.15 171 16 0.094 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0035239 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0035239 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0035239 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0035239 Not Cancer Driver No 306 0.132 557 81 0.145 110
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0035239 Not Cancer Driver No 336 0.168 464 79 0.17 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0035239 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:0035239 Not Cancer Driver No 45 0.079 158 22 0.139 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0035239 Not Cancer Driver No 9 0.079 11 1 0.091 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0035239 Compendium Yes 146 0.158 211 31 0.147 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0035239 Not Cancer Driver No 57 0.094 66 4 0.061 2
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0035239 Not Cancer Driver No 57 0.214 67 17 0.254 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0035239 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0035239 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0035239 Census Yes 84 0.187 291 55 0.189 4
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0035239 Census Yes 82 0.191 290 57 0.197 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0035239 Census, Compendium Yes 164 0.148 231 44 0.19 7
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0035239 Not Cancer Driver No 31 0.104 26 4 0.154 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0035239 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0035239 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0035239 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0035239 Not Cancer Driver No 246 0.128 321 35 0.109 0
PML PML P29590 Protein PML chr15 GO:0035239 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0035239 Not Cancer Driver No 38 0.115 27 6 0.222 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0035239 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0035239 Compendium Yes 118 0.134 246 34 0.138 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0035239 Not Cancer Driver No 54 0.151 69 3 0.043 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0035239 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0035239 Census, Compendium Yes 69 0.282 205 49 0.239 1
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0035239 Census, Compendium Yes 243 0.168 382 67 0.175 18
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0035239 Not Cancer Driver No 73 0.076 505 48 0.095 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0035239 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0035239 Not Cancer Driver No 49 0.098 151 19 0.126 2
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0035239 Not Cancer Driver No 33 0.097 8 0 0.0 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0035239 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0035239 Not Cancer Driver No 52 0.265 19 2 0.105 0
RSPO2 RSPO2 Q6UXX9 R-spondin-2 chr8 GO:0035239 Census Yes 96 0.395 41 10 0.244 1
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0035239 Not Cancer Driver No 1703 0.343 782 281 0.359 51
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0035239 Not Cancer Driver No 454 0.343 949 334 0.352 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0035239 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 GO:0035239 Not Cancer Driver No 135 0.106 526 55 0.105 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0035239 Not Cancer Driver No 195 0.252 86 27 0.314 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0035239 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0035239 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0035239 Not Cancer Driver No 47 0.159 1 0 0.0 0
SGCD_ENST00000435422 SGCD Q92629 Delta-sarcoglycan chr5 GO:0035239 Not Cancer Driver No 67 0.232 74 20 0.27 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0035239 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0035239 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0035239 Not Cancer Driver No 428 0.28 31 13 0.419 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0035239 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0035239 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0035239 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0035239 Compendium Yes 81 0.196 378 59 0.156 2
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0035239 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0035239 Compendium Yes 86 0.169 495 82 0.166 18
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0035239 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0035239 Not Cancer Driver No 44 0.087 443 42 0.095 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 GO:0035239 Not Cancer Driver No 177 0.159 494 78 0.158 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0035239 Not Cancer Driver No 70 0.144 231 30 0.13 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0035239 Not Cancer Driver No 77 0.115 84 14 0.167 6
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0035239 Not Cancer Driver No 22 0.068 27 1 0.037 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0035239 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0035239 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0035239 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0035239 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0035239 Not Cancer Driver No 55 0.307 120 40 0.333 0
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 GO:0035239 Not Cancer Driver No 66 0.148 220 31 0.141 0
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0035239 Not Cancer Driver No 114 0.248 306 75 0.245 6
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0035239 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0035239 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0035239 Census, Compendium Yes 106 0.187 60 16 0.267 25
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0035239 Not Cancer Driver No 200 0.176 223 46 0.206 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0035239 Not Cancer Driver No 154 0.127 367 51 0.139 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0035239 Census, Compendium Yes 229 0.337 398 143 0.359 28
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 GO:0035239 Not Cancer Driver No 66 0.149 218 29 0.133 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0035239 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0035239 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNK4 WNK4 Q96J92 Serine/threonine-protein kinase WNK4 chr17 GO:0035239 Compendium Yes 178 0.143 916 126 0.138 4
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0035239 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0035239 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0035239 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0035239 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0035239 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0035239 Not Cancer Driver No 47 0.132 11 4 0.364 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0035239 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0035239 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0035239 Not Cancer Driver No 148 0.139 762 111 0.146 5