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Total number of protein in "GO:0034976" GO term:  128

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0034976 Census, Compendium Yes 139 0.123 604 73 0.121 2
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0034976 Not Cancer Driver No 23 0.131 20 2 0.1 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0034976 Not Cancer Driver No 88 0.144 166 22 0.133 11
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0034976 Not Cancer Driver No 84 0.127 46 7 0.152 0
ANKS4B ANKS4B Q8N8V4 Ankyrin repeat and SAM domain-containing protein 4B chr16 GO:0034976 Not Cancer Driver No 82 0.197 239 44 0.184 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0034976 Not Cancer Driver No 127 0.102 17 1 0.059 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0034976 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0034976 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0034976 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0034976 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATG10 ATG10 Q9H0Y0 Ubiquitin-like-conjugating enzyme ATG10 chr5 GO:0034976 Not Cancer Driver No 22 0.1 9 1 0.111 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0034976 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0034976 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0034976 Not Cancer Driver No 130 0.13 147 16 0.109 0
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0034976 Not Cancer Driver No 41 0.1 122 13 0.107 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0034976 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0034976 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0034976 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0034976 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0034976 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0034976 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0034976 Census, Compendium Yes 24 0.1 72 5 0.069 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0034976 Not Cancer Driver No 90 0.122 321 39 0.121 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0034976 Not Cancer Driver No 56 0.149 102 14 0.137 0
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 GO:0034976 Not Cancer Driver No 49 0.101 265 23 0.087 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0034976 Not Cancer Driver No 50 0.099 99 20 0.202 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0034976 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0034976 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0034976 Not Cancer Driver No 30 0.135 49 5 0.102 0
COL4A3BP_ENST00000261415 CERT1 Q9Y5P4 Ceramide transfer protein chr5 GO:0034976 Not Cancer Driver No 73 0.117 215 23 0.107 2
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0034976 Census Yes 68 0.131 372 50 0.134 0
CREB3L2 CREB3L2 Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 chr7 GO:0034976 Census Yes 61 0.117 364 46 0.126 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0034976 Not Cancer Driver No 96 0.208 338 67 0.198 1
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0034976 Not Cancer Driver No 17 0.172 0 0 0.0 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0034976 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0034976 Census Yes 29 0.172 160 27 0.169 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0034976 Not Cancer Driver No 34 0.108 181 23 0.127 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0034976 Not Cancer Driver No 28 0.112 11 1 0.091 0
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 GO:0034976 Not Cancer Driver No 30 0.135 107 15 0.14 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0034976 Not Cancer Driver No 110 0.139 36 3 0.083 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0034976 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0034976 Not Cancer Driver No 69 0.119 54 3 0.056 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0034976 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0034976 Not Cancer Driver No 76 0.105 179 16 0.089 29
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0034976 Not Cancer Driver No 35 0.111 59 6 0.102 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0034976 Not Cancer Driver No 118 0.306 117 34 0.291 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0034976 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0034976 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0034976 Not Cancer Driver No 48 0.103 32 5 0.156 0
ERP27 ERP27 Q96DN0 Endoplasmic reticulum resident protein 27 chr12 GO:0034976 Not Cancer Driver No 43 0.158 28 10 0.357 0
ERP44 ERP44 Q9BS26 Endoplasmic reticulum resident protein 44 chr9 GO:0034976 Not Cancer Driver No 43 0.106 43 3 0.07 0
FAM129A NIBAN1 Q9BZQ8 Protein Niban 1 chr1 GO:0034976 Not Cancer Driver No 162 0.175 394 79 0.201 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0034976 Not Cancer Driver No 46 0.1 42 3 0.071 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0034976 Not Cancer Driver No 43 0.101 122 15 0.123 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 GO:0034976 Not Cancer Driver No 55 0.122 287 31 0.108 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0034976 Not Cancer Driver No 56 0.133 146 13 0.089 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0034976 Census Yes 38 0.097 248 17 0.069 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0034976 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0034976 Not Cancer Driver No 73 0.112 282 35 0.124 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0034976 Not Cancer Driver No 132 0.132 373 47 0.126 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0034976 Not Cancer Driver No 390 0.141 581 76 0.131 6
JUN JUN P05412 Transcription factor Jun chr1 GO:0034976 Census Yes 35 0.106 281 25 0.089 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0034976 Not Cancer Driver No 197 0.143 242 29 0.12 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 GO:0034976 Not Cancer Driver No 140 0.133 206 36 0.175 1
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0034976 Not Cancer Driver No 63 0.121 16 4 0.25 9
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0034976 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0034976 Not Cancer Driver No 89 0.234 88 19 0.216 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0034976 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0034976 Not Cancer Driver No 79 0.121 98 13 0.133 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 GO:0034976 Not Cancer Driver No 66 0.167 18 3 0.167 22
NRBF2 NRBF2 Q96F24 Nuclear receptor-binding factor 2 chr10 GO:0034976 Not Cancer Driver No 34 0.118 224 25 0.112 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0034976 Not Cancer Driver No 72 0.108 451 49 0.109 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0034976 Not Cancer Driver No 61 0.12 79 15 0.19 1
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0034976 Not Cancer Driver No 37 0.115 33 3 0.091 0
PDIA2 PDIA2 Q13087 Protein disulfide-isomerase A2 chr16 GO:0034976 Not Cancer Driver No 70 0.133 80 12 0.15 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0034976 Not Cancer Driver No 57 0.113 98 11 0.112 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 GO:0034976 Not Cancer Driver No 81 0.126 147 22 0.15 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0034976 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0034976 Not Cancer Driver No 96 0.132 418 47 0.112 3
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0034976 Not Cancer Driver No 108 0.134 148 23 0.155 11
PML PML P29590 Protein PML chr15 GO:0034976 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0034976 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0034976 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0034976 Not Cancer Driver No 37 0.12 12 0 0.0 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0034976 Not Cancer Driver No 110 0.237 78 15 0.192 31
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0034976 Not Cancer Driver No 49 0.113 140 25 0.179 0
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 GO:0034976 Not Cancer Driver No 93 0.12 423 55 0.13 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0034976 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0034976 Not Cancer Driver No 216 0.175 274 55 0.201 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0034976 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0034976 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0034976 Not Cancer Driver No 27 0.119 11 3 0.273 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0034976 Not Cancer Driver No 17 0.094 69 3 0.043 0
SCAMP5_ENST00000425597 SCAMP5 Q8TAC9 Secretory carrier-associated membrane protein 5 chr15 GO:0034976 Not Cancer Driver No 41 0.174 2 1 0.5 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0034976 Not Cancer Driver No 16 0.072 130 9 0.069 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 GO:0034976 Not Cancer Driver No 285 0.121 1923 235 0.122 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0034976 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0034976 Not Cancer Driver No 7 0.037 122 6 0.049 0
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:0034976 Not Cancer Driver No 71 0.153 60 10 0.167 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0034976 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0034976 Not Cancer Driver No 137 0.143 281 40 0.142 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0034976 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMCO1 TMCO1 Q9UM00 Calcium load-activated calcium channel chr1 GO:0034976 Not Cancer Driver No 31 0.13 49 5 0.102 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0034976 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM117 TMEM117 Q9H0C3 Transmembrane protein 117 chr12 GO:0034976 Not Cancer Driver No 91 0.177 70 12 0.171 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0034976 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 GO:0034976 Not Cancer Driver No 24 0.097 6 0 0.0 0
TMTC3 TMTC3 Q6ZXV5 Protein O-mannosyl-transferase TMTC3 chr12 GO:0034976 Not Cancer Driver No 122 0.133 84 7 0.083 2
TMX1 TMX1 Q9H3N1 Thioredoxin-related transmembrane protein 1 chr14 GO:0034976 Not Cancer Driver No 34 0.121 59 6 0.102 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0034976 Not Cancer Driver No 44 0.1 190 19 0.1 0
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0034976 Not Cancer Driver No 33 0.099 0 0 0.0 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0034976 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0034976 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0034976 Not Cancer Driver No 65 0.182 114 24 0.211 0
TTC23L TTC23L Q6PF05 Tetratricopeptide repeat protein 23-like chr5 GO:0034976 Not Cancer Driver No 52 0.144 70 11 0.157 0
UBA5 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 GO:0034976 Not Cancer Driver No 41 0.101 126 8 0.063 7
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0034976 Not Cancer Driver No 64 0.109 543 58 0.107 0
UFC1 UFC1 Q9Y3C8 Ubiquitin-fold modifier-conjugating enzyme 1 chr1 GO:0034976 Not Cancer Driver No 24 0.144 10 0 0.0 2
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0034976 Not Cancer Driver No 26 0.085 100 7 0.07 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0034976 Not Cancer Driver No 109 0.137 141 24 0.17 0
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0034976 Not Cancer Driver No 10 0.118 0 0 0.0 1
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 GO:0034976 Not Cancer Driver No 169 0.109 161 20 0.124 0
UGGT2 UGGT2 Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 chr13 GO:0034976 Not Cancer Driver No 190 0.125 64 6 0.094 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0034976 Not Cancer Driver No 161 0.122 539 68 0.126 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0034976 Not Cancer Driver No 16 0.066 138 8 0.058 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0034976 Not Cancer Driver No 88 0.109 186 16 0.086 16
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0034976 Not Cancer Driver No 105 0.118 203 10 0.049 39
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0034976 Not Cancer Driver No 19 0.073 169 9 0.053 0