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Total number of protein in "GO:0034765" GO term:  416

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB1_ENST00000265724 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 GO:0034765 Compendium Yes 367 0.287 103 31 0.301 0
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0034765 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0034765 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0034765 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0034765 Not Cancer Driver No 227 0.254 131 29 0.221 9
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0034765 Not Cancer Driver No 131 0.144 244 42 0.172 8
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0034765 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0034765 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGT AGT P01019 Angiotensinogen chr1 GO:0034765 Not Cancer Driver No 85 0.179 33 10 0.303 1
AHNAK AHNAK Q09666 Neuroblast differentiation-associated protein AHNAK chr11 GO:0034765 Not Cancer Driver No 805 0.137 5777 794 0.137 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0034765 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0034765 Census Yes 474 0.121 2281 268 0.117 1
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:0034765 Not Cancer Driver No 90 0.19 0 0 0.0 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0034765 Not Cancer Driver No 46 0.093 85 7 0.082 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0034765 Not Cancer Driver No 770 0.195 2844 566 0.199 4
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0034765 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0034765 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANO9 ANO9 A1A5B4 Anoctamin-9 chr11 GO:0034765 Not Cancer Driver No 108 0.138 64 6 0.094 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0034765 Not Cancer Driver No 96 0.253 29 8 0.276 0
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0034765 Not Cancer Driver No 23 0.112 48 4 0.083 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0034765 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0034765 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARL6IP1 ARL6IP1 Q15041 ADP-ribosylation factor-like protein 6-interacting protein 1 chr16 GO:0034765 Not Cancer Driver No 35 0.172 9 1 0.111 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0034765 Not Cancer Driver No 26 0.138 0 0 0.0 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0034765 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0034765 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0034765 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0034765 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 GO:0034765 Not Cancer Driver No 36 0.129 6 1 0.167 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0034765 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0034765 Not Cancer Driver No 228 0.152 171 46 0.269 52
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0034765 Census Yes 30 0.156 39 2 0.051 0
BDKRB1_ENST00000611804 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0034765 Not Cancer Driver No 68 0.193 3 0 0.0 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0034765 Not Cancer Driver No 65 0.11 456 42 0.092 5
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 GO:0034765 Not Cancer Driver No 54 0.211 0 0 0.0 0
C4orf3_ENST00000504110 C4orf3 Q8WVX3 Uncharacterized protein C4orf3 chr4 GO:0034765 Not Cancer Driver No 11 0.167 18 5 0.278 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0034765 Not Cancer Driver No 31 0.091 43 5 0.116 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0034765 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 GO:0034765 Not Cancer Driver No 416 0.178 917 115 0.125 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0034765 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0034765 Census, Compendium Yes 342 0.158 736 126 0.171 2
CACNA1E_ENST00000621551 CACNA1E Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E chr1 GO:0034765 Not Cancer Driver No 778 0.336 917 339 0.37 14
CACNA1F CACNA1F O60840 Voltage-dependent L-type calcium channel subunit alpha-1F chrX GO:0034765 Not Cancer Driver No 284 0.144 530 78 0.147 20
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0034765 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0034765 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CACNA1I CACNA1I Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I chr22 GO:0034765 Not Cancer Driver No 272 0.122 870 73 0.084 0
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0034765 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0034765 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNA2D2 CACNA2D2 Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2 chr3 GO:0034765 Not Cancer Driver No 126 0.11 185 20 0.108 1
CACNA2D3_ENST00000415676 CACNA2D3 Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 chr3 GO:0034765 Not Cancer Driver No 261 0.239 37 12 0.324 0
CACNA2D4 CACNA2D4 Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 chr12 GO:0034765 Not Cancer Driver No 211 0.186 70 9 0.129 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0034765 Not Cancer Driver No 75 0.125 396 47 0.119 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0034765 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0034765 Not Cancer Driver No 58 0.12 258 30 0.116 0
CACNB4 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 GO:0034765 Not Cancer Driver No 82 0.158 295 49 0.166 1
CACNG1 CACNG1 Q06432 Voltage-dependent calcium channel gamma-1 subunit chr17 GO:0034765 Not Cancer Driver No 36 0.162 0 0 0.0 0
CACNG2 CACNG2 Q9Y698 Voltage-dependent calcium channel gamma-2 subunit chr22 GO:0034765 Not Cancer Driver No 57 0.176 90 16 0.178 1
CACNG3 CACNG3 O60359 Voltage-dependent calcium channel gamma-3 subunit chr16 GO:0034765 Not Cancer Driver No 126 0.4 69 37 0.536 0
CACNG4 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 GO:0034765 Not Cancer Driver No 51 0.156 71 17 0.239 0
CACNG6 CACNG6 Q9BXT2 Voltage-dependent calcium channel gamma-6 subunit chr19 GO:0034765 Not Cancer Driver No 49 0.188 19 2 0.105 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0034765 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALHM1 CALHM1 Q8IU99 Calcium homeostasis modulator protein 1 chr10 GO:0034765 Not Cancer Driver No 53 0.153 76 12 0.158 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0034765 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0034765 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0034765 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0034765 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0034765 Not Cancer Driver No 68 0.095 32 2 0.062 1
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0034765 Not Cancer Driver No 111 0.135 168 11 0.065 52
CASQ1 CASQ1 P31415 Calsequestrin-1 chr1 GO:0034765 Not Cancer Driver No 77 0.194 110 18 0.164 4
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0034765 Not Cancer Driver No 74 0.185 75 16 0.213 4
CATSPER1 CATSPER1 Q8NEC5 Cation channel sperm-associated protein 1 chr11 GO:0034765 Not Cancer Driver No 138 0.177 417 87 0.209 0
CATSPER2_ENST00000396879 CATSPER2 Q96P56 Cation channel sperm-associated protein 2 chr15 GO:0034765 Not Cancer Driver No 73 0.138 103 10 0.097 0
CATSPER3 CATSPER3 Q86XQ3 Cation channel sperm-associated protein 3 chr5 GO:0034765 Not Cancer Driver No 55 0.138 19 2 0.105 0
CATSPER4 CATSPER4 Q7RTX7 Cation channel sperm-associated protein 4 chr1 GO:0034765 Not Cancer Driver No 79 0.167 97 19 0.196 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0034765 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0034765 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBARP_ENST00000382477 CBARP Q8N350 Voltage-dependent calcium channel beta subunit-associated regulatory protein chr19 GO:0034765 Not Cancer Driver No 41 0.058 661 33 0.05 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0034765 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0034765 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0034765 Not Cancer Driver No 80 0.144 312 46 0.147 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0034765 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0034765 Not Cancer Driver No 207 0.152 105 10 0.095 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0034765 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0034765 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0034765 Not Cancer Driver No 27 0.138 70 12 0.171 0
CLCN1 CLCN1 P35523 Chloride channel protein 1 chr7 GO:0034765 Not Cancer Driver No 224 0.227 355 77 0.217 54
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 GO:0034765 Not Cancer Driver No 124 0.138 224 38 0.17 8
CLCNKA CLCNKA P51800 Chloride channel protein ClC-Ka chr1 GO:0034765 Not Cancer Driver No 92 0.134 35 3 0.086 1
CLCNKB CLCNKB P51801 Chloride channel protein ClC-Kb chr1 GO:0034765 Not Cancer Driver No 104 0.151 23 9 0.391 5
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 GO:0034765 Not Cancer Driver No 32 0.133 27 5 0.185 0
CLIC2 CLIC2 O15247 Chloride intracellular channel protein 2 chrX GO:0034765 Not Cancer Driver No 46 0.186 58 6 0.103 1
CLIC3 CLIC3 O95833 Chloride intracellular channel protein 3 chr9 GO:0034765 Not Cancer Driver No 23 0.097 36 3 0.083 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0034765 Not Cancer Driver No 24 0.095 49 4 0.082 0
CLIC5 CLIC5 Q9NZA1 Chloride intracellular channel protein 5 chr6 GO:0034765 Not Cancer Driver No 50 0.122 205 22 0.107 0
CLIC6 CLIC6 Q96NY7 Chloride intracellular channel protein 6 chr21 GO:0034765 Not Cancer Driver No 60 0.085 500 21 0.042 0
CLTRN CLTRN Q9HBJ8 Collectrin chrX GO:0034765 Not Cancer Driver No 28 0.126 28 4 0.143 0
CNIH2 CNIH2 Q6PI25 Protein cornichon homolog 2 chr11 GO:0034765 Not Cancer Driver No 20 0.125 0 0 0.0 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0034765 Not Cancer Driver No 72 0.13 269 43 0.16 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 GO:0034765 Not Cancer Driver No 21 0.111 17 0 0.0 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 GO:0034765 Not Cancer Driver No 7 0.111 15 2 0.133 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0034765 Not Cancer Driver No 88 0.12 436 60 0.138 0
CRBN CRBN Q96SW2 Protein cereblon chr3 GO:0034765 Not Cancer Driver No 52 0.118 76 10 0.132 1
CRH CRH P06850 Corticoliberin chr8 GO:0034765 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0034765 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0034765 Not Cancer Driver No 75 0.169 0 0 0.0 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0034765 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0034765 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0034765 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0034765 Not Cancer Driver No 32 0.256 38 16 0.421 0
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0034765 Not Cancer Driver No 109 0.191 11 3 0.273 65
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0034765 Not Cancer Driver No 193 0.135 114 11 0.096 0
DHRS7C DHRS7C A6NNS2 Dehydrogenase/reductase SDR family member 7C chr17 GO:0034765 Not Cancer Driver No 80 0.256 0 0 0.0 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0034765 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0034765 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMD DMD P11532 Dystrophin chrX GO:0034765 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 GO:0034765 Not Cancer Driver No 25 0.111 83 7 0.084 3
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0034765 Census Yes 138 0.159 270 43 0.159 22
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0034765 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0034765 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0034765 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0034765 Not Cancer Driver No 26 0.062 109 0 0.0 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0034765 Not Cancer Driver No 69 0.29 140 44 0.314 3
EHD3 EHD3 Q9NZN3 EH domain-containing protein 3 chr2 GO:0034765 Not Cancer Driver No 104 0.194 77 18 0.234 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0034765 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0034765 Not Cancer Driver No 27 0.14 9 1 0.111 1
F2 F2 P00734 Prothrombin chr11 GO:0034765 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0034765 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0034765 Not Cancer Driver No 43 0.112 46 4 0.087 0
FAM173A ANTKMT Q9BQD7 Adenine nucleotide translocase lysine N-methyltransferase chr16 GO:0034765 Not Cancer Driver No 10 0.043 37 3 0.081 0
FAM173B ATPSCKMT Q6P4H8 ATP synthase subunit C lysine N-methyltransferase chr5 GO:0034765 Not Cancer Driver No 41 0.176 10 1 0.1 0
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 GO:0034765 Not Cancer Driver No 20 0.089 68 5 0.074 0
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 GO:0034765 Not Cancer Driver No 74 0.305 102 30 0.294 1
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0034765 Not Cancer Driver No 70 0.286 96 33 0.344 2
FGF14_ENST00000376143 FGF14 Q92915 Fibroblast growth factor 14 chr13 GO:0034765 Not Cancer Driver No 72 0.291 93 30 0.323 1
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX GO:0034765 Not Cancer Driver No 56 0.173 51 7 0.137 13
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0034765 Not Cancer Driver No 15 0.139 39 7 0.179 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0034765 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLNA FLNA P21333 Filamin-A chrX GO:0034765 Census Yes 416 0.157 1456 214 0.147 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0034765 Not Cancer Driver No 124 0.196 327 70 0.214 3
FXYD1_ENST00000455515 FXYD1 O00168 Phospholemman chr19 GO:0034765 Not Cancer Driver No 10 0.109 22 4 0.182 0
FXYD2 FXYD2 P54710 Sodium/potassium-transporting ATPase subunit gamma chr11 GO:0034765 Not Cancer Driver No 2 0.03 20 2 0.1 1
FXYD3_ENST00000604404 FXYD3 Q14802 FXYD domain-containing ion transport regulator 3 chr19 GO:0034765 Not Cancer Driver No 16 0.184 16 1 0.062 0
FXYD4_ENST00000476166 FXYD4 P59646 FXYD domain-containing ion transport regulator 4 chr10 GO:0034765 Not Cancer Driver No 9 0.101 5 1 0.2 0
FXYD5_ENST00000590686 FXYD5 Q96DB9 FXYD domain-containing ion transport regulator 5 chr19 GO:0034765 Not Cancer Driver No 31 0.174 136 18 0.132 0
FXYD6_ENST00000260282 FXYD6 Q9H0Q3 FXYD domain-containing ion transport regulator 6 chr11 GO:0034765 Not Cancer Driver No 14 0.147 27 4 0.148 0
FXYD7 FXYD7 P58549 FXYD domain-containing ion transport regulator 7 chr19 GO:0034765 Not Cancer Driver No 7 0.087 43 2 0.047 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0034765 Not Cancer Driver No 92 0.171 70 13 0.186 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0034765 Not Cancer Driver No 86 0.167 28 3 0.107 58
GAL GAL P22466 Galanin peptides chr11 GO:0034765 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALR2 GALR2 O43603 Galanin receptor type 2 chr17 GO:0034765 Not Cancer Driver No 40 0.103 0 0 0.0 0
GEM GEM P55040 GTP-binding protein GEM chr8 GO:0034765 Not Cancer Driver No 64 0.216 96 22 0.229 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0034765 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0034765 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0034765 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLRX_ENST00000505427 GLRX P35754 Glutaredoxin-1 chr5 GO:0034765 Not Cancer Driver No 14 0.132 0 0 0.0 0
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:0034765 Not Cancer Driver No 60 0.152 16 1 0.062 1
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 GO:0034765 Census Yes 56 0.121 263 34 0.129 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0034765 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0034765 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0034765 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR89A GPR89A B7ZAQ6 Golgi pH regulator A chr1 GO:0034765 Not Cancer Driver No 22 0.048 1 0 0.0 0
GPR89B GPR89B P0CG08 Golgi pH regulator B chr1 GO:0034765 Not Cancer Driver No 11 0.024 1 0 0.0 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0034765 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0034765 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0034765 Not Cancer Driver No 26 0.108 18 1 0.056 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0034765 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0034765 Not Cancer Driver No 97 0.145 454 60 0.132 0
HECW1 HECW1 Q76N89 E3 ubiquitin-protein ligase HECW1 chr7 GO:0034765 Not Cancer Driver No 420 0.262 748 191 0.255 0
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 GO:0034765 Not Cancer Driver No 348 0.221 845 195 0.231 4
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0034765 Not Cancer Driver No 24 0.124 42 4 0.095 3
HRC HRC P23327 Sarcoplasmic reticulum histidine-rich calcium-binding protein chr19 GO:0034765 Not Cancer Driver No 110 0.157 612 98 0.16 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0034765 Not Cancer Driver No 93 0.146 286 38 0.133 0
HTT HTT P42858 Huntingtin chr4 GO:0034765 Not Cancer Driver No 336 0.107 666 69 0.104 2
HVCN1_ENST00000620084 HVCN1 Q96D96 Voltage-gated hydrogen channel 1 chr12 GO:0034765 Not Cancer Driver No 51 0.187 52 13 0.25 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0034765 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 GO:0034765 Not Cancer Driver No 36 0.107 18 2 0.111 5
IL13 IL13 P35225 Interleukin-13 chr5 GO:0034765 Not Cancer Driver No 20 0.137 0 0 0.0 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0034765 Not Cancer Driver No 14 0.084 24 3 0.125 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0034765 Not Cancer Driver No 103 0.129 84 10 0.119 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 GO:0034765 Not Cancer Driver No 131 0.198 421 89 0.211 0
JPH2 JPH2 Q9BR39 Junctophilin-2 chr20 GO:0034765 Not Cancer Driver No 137 0.197 542 97 0.179 4
JPH3 JPH3 Q8WXH2 Junctophilin-3 chr16 GO:0034765 Not Cancer Driver No 130 0.174 534 92 0.172 0
JPH4_ENST00000356300 JPH4 Q96JJ6 Junctophilin-4 chr14 GO:0034765 Not Cancer Driver No 57 0.091 516 54 0.105 0
JSRP1 JSRP1 Q96MG2 Junctional sarcoplasmic reticulum protein 1 chr19 GO:0034765 Not Cancer Driver No 39 0.118 313 39 0.125 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0034765 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA10 KCNA10 Q16322 Potassium voltage-gated channel subfamily A member 10 chr1 GO:0034765 Not Cancer Driver No 118 0.231 110 30 0.273 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0034765 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA3 KCNA3 P22001 Potassium voltage-gated channel subfamily A member 3 chr1 GO:0034765 Not Cancer Driver No 120 0.209 169 16 0.095 0
KCNA4 KCNA4 P22459 Potassium voltage-gated channel subfamily A member 4 chr11 GO:0034765 Not Cancer Driver No 213 0.326 233 82 0.352 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0034765 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNA6 KCNA6 P17658 Potassium voltage-gated channel subfamily A member 6 chr12 GO:0034765 Not Cancer Driver No 178 0.336 159 55 0.346 0
KCNA7 KCNA7 Q96RP8 Potassium voltage-gated channel subfamily A member 7 chr19 GO:0034765 Not Cancer Driver No 62 0.136 48 8 0.167 0
KCNAB1 KCNAB1 Q14722 Voltage-gated potassium channel subunit beta-1 chr3 GO:0034765 Not Cancer Driver No 89 0.212 83 23 0.277 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0034765 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNB2 KCNB2 Q92953 Potassium voltage-gated channel subfamily B member 2 chr8 GO:0034765 Not Cancer Driver No 372 0.408 502 200 0.398 0
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0034765 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0034765 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCNC3 KCNC3 Q14003 Potassium voltage-gated channel subfamily C member 3 chr19 GO:0034765 Not Cancer Driver No 76 0.1 405 29 0.072 4
KCNC4 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 GO:0034765 Not Cancer Driver No 105 0.165 244 38 0.156 0
KCND1 KCND1 Q9NSA2 Potassium voltage-gated channel subfamily D member 1 chrX GO:0034765 Not Cancer Driver No 97 0.15 180 30 0.167 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0034765 Not Cancer Driver No 220 0.349 195 62 0.318 0
KCND3 KCND3 Q9UK17 Potassium voltage-gated channel subfamily D member 3 chr1 GO:0034765 Not Cancer Driver No 172 0.263 202 44 0.218 5
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0034765 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0034765 Not Cancer Driver No 25 0.203 2 0 0.0 5
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 GO:0034765 Not Cancer Driver No 28 0.272 24 2 0.083 0
KCNE4 KCNE4 Q8WWG9 Potassium voltage-gated channel subfamily E member 4 chr2 GO:0034765 Not Cancer Driver No 26 0.118 94 18 0.191 0
KCNE5 KCNE5 Q9UJ90 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 chrX GO:0034765 Not Cancer Driver No 35 0.246 68 26 0.382 0
KCNF1 KCNF1 Q9H3M0 Potassium voltage-gated channel subfamily F member 1 chr2 GO:0034765 Not Cancer Driver No 116 0.235 73 13 0.178 0
KCNG1 KCNG1 Q9UIX4 Potassium voltage-gated channel subfamily G member 1 chr20 GO:0034765 Not Cancer Driver No 123 0.24 50 12 0.24 0
KCNG2 KCNG2 Q9UJ96 Potassium voltage-gated channel subfamily G member 2 chr18 GO:0034765 Not Cancer Driver No 75 0.161 71 4 0.056 0
KCNG3 KCNG3 Q8TAE7 Potassium voltage-gated channel subfamily G member 3 chr2 GO:0034765 Not Cancer Driver No 35 0.08 22 1 0.045 0
KCNG4 KCNG4 Q8TDN1 Potassium voltage-gated channel subfamily G member 4 chr16 GO:0034765 Not Cancer Driver No 117 0.225 47 10 0.213 0
KCNH1 KCNH1 O95259 Potassium voltage-gated channel subfamily H member 1 chr1 GO:0034765 Not Cancer Driver No 247 0.25 248 70 0.282 10
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0034765 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNH3 KCNH3 Q9ULD8 Potassium voltage-gated channel subfamily H member 3 chr12 GO:0034765 Not Cancer Driver No 148 0.137 436 58 0.133 0
KCNH4 KCNH4 Q9UQ05 Potassium voltage-gated channel subfamily H member 4 chr17 GO:0034765 Not Cancer Driver No 168 0.165 402 51 0.127 0
KCNH5 KCNH5 Q8NCM2 Potassium voltage-gated channel subfamily H member 5 chr14 GO:0034765 Not Cancer Driver No 308 0.312 280 90 0.321 0
KCNH6 KCNH6 Q9H252 Potassium voltage-gated channel subfamily H member 6 chr17 GO:0034765 Not Cancer Driver No 202 0.203 284 67 0.236 0
KCNH7 KCNH7 Q9NS40 Potassium voltage-gated channel subfamily H member 7 chr2 GO:0034765 Not Cancer Driver No 324 0.271 508 138 0.272 0
KCNH8 KCNH8 Q96L42 Potassium voltage-gated channel subfamily H member 8 chr3 GO:0034765 Not Cancer Driver No 279 0.252 369 103 0.279 0
KCNIP2_ENST00000356640 KCNIP2 Q9NS61 Kv channel-interacting protein 2 chr10 GO:0034765 Not Cancer Driver No 34 0.126 89 16 0.18 0
KCNJ1 KCNJ1 P48048 ATP-sensitive inward rectifier potassium channel 1 chr11 GO:0034765 Not Cancer Driver No 83 0.212 10 0 0.0 13
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0034765 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0034765 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNJ12_ENST00000331718 KCNJ12 Q14500 ATP-sensitive inward rectifier potassium channel 12 chr17 GO:0034765 Not Cancer Driver No 248 0.573 50 27 0.54 0
KCNJ13_ENST00000410029 KCNJ13 O60928 Inward rectifier potassium channel 13 chr2 GO:0034765 Not Cancer Driver No 39 0.108 44 3 0.068 3
KCNJ14_ENST00000342291 KCNJ14 Q9UNX9 ATP-sensitive inward rectifier potassium channel 14 chr19 GO:0034765 Not Cancer Driver No 56 0.128 73 10 0.137 0
KCNJ15_ENST00000398934 KCNJ15 Q99712 ATP-sensitive inward rectifier potassium channel 15 chr21 GO:0034765 Not Cancer Driver No 85 0.227 12 2 0.167 0
KCNJ16_ENST00000283936 KCNJ16 Q9NPI9 Inward rectifier potassium channel 16 chr17 GO:0034765 Not Cancer Driver No 88 0.211 38 8 0.211 5
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0034765 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNJ3 KCNJ3 P48549 G protein-activated inward rectifier potassium channel 1 chr2 GO:0034765 Not Cancer Driver No 189 0.377 162 64 0.395 0
KCNJ4 KCNJ4 P48050 Inward rectifier potassium channel 4 chr22 GO:0034765 Not Cancer Driver No 103 0.231 62 16 0.258 0
KCNJ5_ENST00000533599 KCNJ5 P48544 G protein-activated inward rectifier potassium channel 4 chr11 GO:0034765 Census Yes 87 0.208 51 6 0.118 6
KCNJ6_ENST00000645093 KCNJ6 P48051 G protein-activated inward rectifier potassium channel 2 chr21 GO:0034765 Not Cancer Driver No 106 0.251 75 13 0.173 1
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0034765 Not Cancer Driver No 99 0.233 68 22 0.324 1
KCNJ9 KCNJ9 Q92806 G protein-activated inward rectifier potassium channel 3 chr1 GO:0034765 Not Cancer Driver No 47 0.12 67 1 0.015 0
KCNK10_ENST00000340700 KCNK10 P57789 Potassium channel subfamily K member 10 chr14 GO:0034765 Not Cancer Driver No 138 0.257 174 47 0.27 0
KCNK12 KCNK12 Q9HB15 Potassium channel subfamily K member 12 chr2 GO:0034765 Not Cancer Driver No 6 0.014 29 0 0.0 0
KCNK13 KCNK13 Q9HB14 Potassium channel subfamily K member 13 chr14 GO:0034765 Not Cancer Driver No 99 0.243 32 8 0.25 0
KCNK15 KCNK15 Q9H427 Potassium channel subfamily K member 15 chr20 GO:0034765 Not Cancer Driver No 54 0.164 32 8 0.25 0
KCNK16_ENST00000373229 KCNK16 Q96T55 Potassium channel subfamily K member 16 chr6 GO:0034765 Not Cancer Driver No 63 0.204 14 1 0.071 0
KCNK17 KCNK17 Q96T54 Potassium channel subfamily K member 17 chr6 GO:0034765 Not Cancer Driver No 46 0.139 31 11 0.355 0
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0034765 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNK5 KCNK5 O95279 Potassium channel subfamily K member 5 chr6 GO:0034765 Not Cancer Driver No 94 0.188 206 36 0.175 0
KCNK6 KCNK6 Q9Y257 Potassium channel subfamily K member 6 chr19 GO:0034765 Not Cancer Driver No 39 0.125 22 4 0.182 0
KCNK7 KCNK7 Q9Y2U2 Potassium channel subfamily K member 7 chr11 GO:0034765 Not Cancer Driver No 31 0.101 6 1 0.167 0
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 GO:0034765 Not Cancer Driver No 222 0.18 225 39 0.173 5
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0034765 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0034765 Not Cancer Driver No 60 0.141 31 6 0.194 3
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0034765 Not Cancer Driver No 78 0.115 219 20 0.091 132
KCNQ2 KCNQ2 O43526 Potassium voltage-gated channel subfamily KQT member 2 chr20 GO:0034765 Not Cancer Driver No 171 0.196 393 81 0.206 37
KCNQ3 KCNQ3 O43525 Potassium voltage-gated channel subfamily KQT member 3 chr8 GO:0034765 Not Cancer Driver No 249 0.286 411 109 0.265 3
KCNQ4_ENST00000347132 KCNQ4 P56696 Potassium voltage-gated channel subfamily KQT member 4 chr1 GO:0034765 Not Cancer Driver No 83 0.119 267 31 0.116 7
KCNQ5_ENST00000370398 KCNQ5 Q9NR82 Potassium voltage-gated channel subfamily KQT member 5 chr6 GO:0034765 Not Cancer Driver No 241 0.259 408 96 0.235 4
KCNRG KCNRG Q8N5I3 Potassium channel regulatory protein chr13 GO:0034765 Not Cancer Driver No 44 0.162 47 7 0.149 0
KCNS1 KCNS1 Q96KK3 Potassium voltage-gated channel subfamily S member 1 chr20 GO:0034765 Not Cancer Driver No 52 0.099 64 3 0.047 0
KCNS2_ENST00000521839 KCNS2 Q9ULS6 Potassium voltage-gated channel subfamily S member 2 chr8 GO:0034765 Not Cancer Driver No 124 0.26 29 7 0.241 0
KCNS3_ENST00000304101 KCNS3 Q9BQ31 Potassium voltage-gated channel subfamily S member 3 chr2 GO:0034765 Not Cancer Driver No 103 0.21 23 2 0.087 0
KCNU1 KCNU1 A8MYU2 Potassium channel subfamily U member 1 chr8 GO:0034765 Not Cancer Driver No 279 0.243 140 40 0.286 0
KCNV1 KCNV1 Q6PIU1 Potassium voltage-gated channel subfamily V member 1 chr8 GO:0034765 Not Cancer Driver No 147 0.294 30 4 0.133 0
KCNV2 KCNV2 Q8TDN2 Potassium voltage-gated channel subfamily V member 2 chr9 GO:0034765 Not Cancer Driver No 104 0.191 120 22 0.183 5
KEL KEL P23276 Kell blood group glycoprotein chr7 GO:0034765 Compendium Yes 232 0.317 117 39 0.333 0
KLHL24_ENST00000242810 KLHL24 Q6TFL4 Kelch-like protein 24 chr3 GO:0034765 Not Cancer Driver No 102 0.17 17 6 0.353 0
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0034765 Not Cancer Driver No 38 0.275 90 27 0.3 0
LRRC26 LRRC26 Q2I0M4 Leucine-rich repeat-containing protein 26 chr9 GO:0034765 Not Cancer Driver No 3 0.009 41 2 0.049 0
LRRC38 LRRC38 Q5VT99 Leucine-rich repeat-containing protein 38 chr1 GO:0034765 Not Cancer Driver No 24 0.082 12 2 0.167 0
LRRC52 LRRC52 Q8N7C0 Leucine-rich repeat-containing protein 52 chr1 GO:0034765 Not Cancer Driver No 61 0.195 15 4 0.267 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0034765 Not Cancer Driver No 49 0.059 568 27 0.048 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0034765 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0034765 Not Cancer Driver No 54 0.205 47 13 0.277 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0034765 Not Cancer Driver No 129 0.182 124 26 0.21 0
MRLN_ENST00000414264 MRLN P0DMT0 Myoregulin chr10 GO:0034765 Not Cancer Driver No 1 0.022 0 0 0.0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0034765 Not Cancer Driver No 104 0.287 8 1 0.125 0
NALCN NALCN Q8IZF0 Sodium leak channel NALCN chr13 GO:0034765 Not Cancer Driver No 499 0.287 260 74 0.285 11
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 GO:0034765 Not Cancer Driver No 14 0.173 4 0 0.0 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0034765 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0034765 Not Cancer Driver No 126 0.129 463 60 0.13 4
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0034765 Not Cancer Driver No 186 0.349 103 33 0.32 0
NETO2 NETO2 Q8NC67 Neuropilin and tolloid-like protein 2 chr16 GO:0034765 Not Cancer Driver No 71 0.135 102 22 0.216 0
NIPSNAP2 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 GO:0034765 Not Cancer Driver No 30 0.105 6 1 0.167 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0034765 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0034765 Not Cancer Driver No 158 0.186 257 54 0.21 2
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0034765 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0034765 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0034765 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0034765 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPSR1_ENST00000360581 NPSR1 Q6W5P4 Neuropeptide S receptor chr7 GO:0034765 Not Cancer Driver No 111 0.299 9 7 0.778 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0034765 Not Cancer Driver No 85 0.203 23 1 0.043 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0034765 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0034765 Not Cancer Driver No 81 0.219 0 0 0.0 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0034765 Not Cancer Driver No 107 0.268 58 27 0.466 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0034765 Not Cancer Driver No 57 0.214 67 17 0.254 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0034765 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0034765 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0034765 Not Cancer Driver No 50 0.152 10 5 0.5 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0034765 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0034765 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0034765 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0034765 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0034765 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDZK1_ENST00000344770 PDZK1 Q5T2W1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3 chr1 GO:0034765 Not Cancer Driver No 39 0.075 248 14 0.056 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0034765 Not Cancer Driver No 166 0.132 782 101 0.129 1
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0034765 Not Cancer Driver No 31 0.104 26 4 0.154 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0034765 Not Cancer Driver No 318 0.289 121 39 0.322 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0034765 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0034765 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0034765 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0034765 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0034765 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLN PLN P26678 Cardiac phospholamban chr6 GO:0034765 Not Cancer Driver No 10 0.192 0 0 0.0 3
PLP1 PLP1 P60201 Myelin proteolipid protein chrX GO:0034765 Not Cancer Driver No 49 0.177 5 1 0.2 72
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 GO:0034765 Not Cancer Driver No 79 0.157 42 10 0.238 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0034765 Not Cancer Driver No 19 0.092 43 4 0.093 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0034765 Census Yes 53 0.151 24 0 0.0 2
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0034765 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRNP PRNP P04156 Major prion protein chr20 GO:0034765 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0034765 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0034765 Not Cancer Driver No 68 0.152 89 16 0.18 7
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0034765 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0034765 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0034765 Not Cancer Driver No 139 0.152 214 28 0.131 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0034765 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0034765 Not Cancer Driver No 10 0.054 42 5 0.119 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0034765 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRF2 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0034765 Not Cancer Driver No 216 0.175 274 55 0.201 0
RELN RELN P78509 Reelin chr7 GO:0034765 Not Cancer Driver No 761 0.22 107 19 0.178 7
REM1 REM1 O75628 GTP-binding protein REM 1 chr20 GO:0034765 Not Cancer Driver No 75 0.252 133 38 0.286 0
RGN RGN Q15493 Regucalcin chrX GO:0034765 Not Cancer Driver No 38 0.127 14 3 0.214 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0034765 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0034765 Not Cancer Driver No 68 0.332 5 4 0.8 0
RGS7_ENST00000366563 RGS7 P49802 Regulator of G-protein signaling 7 chr1 GO:0034765 Census, Compendium Yes 196 0.396 150 50 0.333 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0034765 Compendium Yes 82 0.122 277 39 0.141 4
RNF207 RNF207 Q6ZRF8 RING finger protein 207 chr1 GO:0034765 Not Cancer Driver No 48 0.076 198 13 0.066 0
RRAD RRAD P55042 GTP-binding protein RAD chr16 GO:0034765 Not Cancer Driver No 46 0.149 142 14 0.099 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0034765 Not Cancer Driver No 1703 0.343 782 281 0.359 51
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0034765 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0034765 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0034765 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0034765 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0034765 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0034765 Not Cancer Driver No 46 0.214 52 7 0.135 2
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 GO:0034765 Not Cancer Driver No 415 0.207 432 83 0.192 6
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0034765 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 GO:0034765 Not Cancer Driver No 324 0.176 372 80 0.215 60
SCN4B SCN4B Q8IWT1 Sodium channel subunit beta-4 chr11 GO:0034765 Not Cancer Driver No 23 0.101 46 4 0.087 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0034765 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0034765 Not Cancer Driver No 395 0.235 171 43 0.251 0
SCN8A SCN8A Q9UQD0 Sodium channel protein type 8 subunit alpha chr12 GO:0034765 Not Cancer Driver No 290 0.146 460 75 0.163 28
SCN9A_ENST00000642356 SCN9A Q15858 Sodium channel protein type 9 subunit alpha chr2 GO:0034765 Not Cancer Driver No 461 0.232 490 126 0.257 21
SELENON SELENON Q9NZV5 Selenoprotein N chr1 GO:0034765 Not Cancer Driver No 53 0.09 93 5 0.054 11
SESTD1 SESTD1 Q86VW0 SEC14 domain and spectrin repeat-containing protein 1 chr2 GO:0034765 Not Cancer Driver No 100 0.144 126 18 0.143 0
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0034765 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC30A1 SLC30A1 Q9Y6M5 Zinc transporter 1 chr1 GO:0034765 Not Cancer Driver No 49 0.097 144 9 0.062 0
SLC30A5 SLC30A5 Q8TAD4 Zinc transporter 5 chr5 GO:0034765 Not Cancer Driver No 58 0.076 33 0 0.0 0
SLC31A2 SLC31A2 O15432 Probable low affinity copper uptake protein 2 chr9 GO:0034765 Not Cancer Driver No 14 0.098 0 0 0.0 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0034765 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC43A1_ENST00000528450 SLC43A1 O75387 Large neutral amino acids transporter small subunit 3 chr11 GO:0034765 Not Cancer Driver No 64 0.114 55 10 0.182 0
SLC43A2_ENST00000301335 SLC43A2 Q8N370 Large neutral amino acids transporter small subunit 4 chr17 GO:0034765 Not Cancer Driver No 51 0.09 31 8 0.258 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0034765 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0034765 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0034765 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0034765 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 GO:0034765 Not Cancer Driver No 77 0.093 464 38 0.082 0
SLN_ENST00000525934 SLN O00631 Sarcolipin chr11 GO:0034765 Not Cancer Driver No 8 0.258 0 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0034765 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNTA1 SNTA1 Q13424 Alpha-1-syntrophin chr20 GO:0034765 Not Cancer Driver No 43 0.085 238 14 0.059 2
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0034765 Not Cancer Driver No 82 0.125 293 39 0.133 0
SRI SRI P30626 Sorcin chr7 GO:0034765 Not Cancer Driver No 15 0.076 32 2 0.062 0
STAC STAC Q99469 SH3 and cysteine-rich domain-containing protein chr3 GO:0034765 Not Cancer Driver No 107 0.266 196 55 0.281 0
STAC2 STAC2 Q6ZMT1 SH3 and cysteine-rich domain-containing protein 2 chr17 GO:0034765 Not Cancer Driver No 56 0.136 228 36 0.158 0
STAC3 STAC3 Q96MF2 SH3 and cysteine-rich domain-containing protein 3 chr12 GO:0034765 Not Cancer Driver No 50 0.137 192 30 0.156 1
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0034765 Not Cancer Driver No 70 0.102 387 45 0.116 13
STIM2_ENST00000467087 STIM2 Q9P246 Stromal interaction molecule 2 chr4 GO:0034765 Not Cancer Driver No 82 0.11 387 45 0.116 0
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:0034765 Not Cancer Driver No 27 0.092 61 4 0.066 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0034765 Not Cancer Driver No 64 0.117 182 19 0.104 0
STOM STOM P27105 Stomatin chr9 GO:0034765 Not Cancer Driver No 23 0.08 44 3 0.068 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0034765 Not Cancer Driver No 10 0.099 76 7 0.092 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 GO:0034765 Not Cancer Driver No 21 0.071 111 2 0.018 0
TCAF1 TCAF1 Q9Y4C2 TRPM8 channel-associated factor 1 chr7 GO:0034765 Not Cancer Driver No 43 0.047 18 3 0.167 0
TCAF2_ENST00000441159 TCAF2 A6NFQ2 TRPM8 channel-associated factor 2 chr7 GO:0034765 Not Cancer Driver No 61 0.066 38 12 0.316 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0034765 Compendium Yes 68 0.082 102 6 0.059 5
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0034765 Not Cancer Driver No 31 0.145 73 6 0.082 0
THADA_ENST00000405975 THADA Q6YHU6 Thyroid adenoma-associated protein chr2 GO:0034765 Not Cancer Driver No 204 0.104 63 6 0.095 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0034765 Not Cancer Driver No 24 0.149 5 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0034765 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMC1 TMC1 Q8TDI8 Transmembrane channel-like protein 1 chr9 GO:0034765 Not Cancer Driver No 121 0.159 97 10 0.103 2
TMC2 TMC2 Q8TDI7 Transmembrane channel-like protein 2 chr20 GO:0034765 Not Cancer Driver No 180 0.199 293 44 0.15 0
TMEM109 TMEM109 Q9BVC6 Transmembrane protein 109 chr11 GO:0034765 Not Cancer Driver No 39 0.16 7 0 0.0 0
TMEM37 TMEM37 Q8WXS4 Voltage-dependent calcium channel gamma-like subunit chr2 GO:0034765 Not Cancer Driver No 34 0.179 0 0 0.0 0
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0034765 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0034765 Not Cancer Driver No 47 0.162 37 7 0.189 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0034765 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0034765 Not Cancer Driver No 24 0.103 45 3 0.067 0
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 GO:0034765 Not Cancer Driver No 114 0.14 99 18 0.182 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 GO:0034765 Not Cancer Driver No 73 0.097 16 0 0.0 0
TRDN TRDN Q13061 Triadin chr6 GO:0034765 Not Cancer Driver No 129 0.177 639 102 0.16 1
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0034765 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPC1 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0034765 Not Cancer Driver No 143 0.18 52 11 0.212 0
TRPM5 TRPM5 Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 chr11 GO:0034765 Not Cancer Driver No 123 0.106 186 19 0.102 0
TSPAN13 TSPAN13 O95857 Tetraspanin-13 chr7 GO:0034765 Not Cancer Driver No 17 0.083 3 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0034765 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0034765 Not Cancer Driver No 64 0.109 543 58 0.107 0
UTRN UTRN P46939 Utrophin chr6 GO:0034765 Not Cancer Driver No 476 0.139 1283 183 0.143 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0034765 Not Cancer Driver No 7 0.06 47 4 0.085 3
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0034765 Not Cancer Driver No 38 0.134 36 4 0.111 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 GO:0034765 Not Cancer Driver No 57 0.14 68 11 0.162 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0034765 Not Cancer Driver No 66 0.109 30 7 0.233 2
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0034765 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0034765 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0034765 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNK4 WNK4 Q96J92 Serine/threonine-protein kinase WNK4 chr17 GO:0034765 Compendium Yes 178 0.143 916 126 0.138 4
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0034765 Not Cancer Driver No 112 0.129 422 57 0.135 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0034765 Not Cancer Driver No 28 0.246 35 11 0.314 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0034765 Census Yes 32 0.125 41 3 0.073 0
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0034765 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0034765 Not Cancer Driver No 67 0.141 23 0 0.0 3