Total number of protein in "GO:0034599" GO term: 173
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABCC1 | ABCC1 | P33527 | Multidrug resistance-associated protein 1 | chr16 | GO:0034599 | Not Cancer Driver | No | 199 | 0.13 | 123 | 22 | 0.179 | 1 |
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0034599 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ADNP2 | ADNP2 | Q6IQ32 | Activity-dependent neuroprotector homeobox protein 2 | chr18 | GO:0034599 | Not Cancer Driver | No | 133 | 0.118 | 475 | 53 | 0.112 | 0 |
ADPRHL2 | ADPRS | Q9NX46 | ADP-ribosylhydrolase ARH3 | chr1 | GO:0034599 | Not Cancer Driver | No | 32 | 0.088 | 49 | 4 | 0.082 | 1 |
AGAP3_ENST00000622464 | AGAP3 | Q96P47 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 | chr7 | GO:0034599 | Not Cancer Driver | No | 116 | 0.133 | 404 | 55 | 0.136 | 0 |
AIF1 | AIF1 | P55008 | Allograft inflammatory factor 1 | chr6 | GO:0034599 | Not Cancer Driver | No | 14 | 0.095 | 61 | 6 | 0.098 | 0 |
AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0034599 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0034599 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0034599 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
ALDH3B1 | ALDH3B1 | P43353 | Aldehyde dehydrogenase family 3 member B1 | chr11 | GO:0034599 | Not Cancer Driver | No | 36 | 0.077 | 23 | 6 | 0.261 | 0 |
ANKZF1 | ANKZF1 | Q9H8Y5 | Ankyrin repeat and zinc finger domain-containing protein 1 | chr2 | GO:0034599 | Not Cancer Driver | No | 77 | 0.106 | 507 | 57 | 0.112 | 0 |
ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0034599 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0034599 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0034599 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0034599 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0034599 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0034599 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:0034599 | Not Cancer Driver | No | 152 | 0.129 | 121 | 10 | 0.083 | 9 |
ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | GO:0034599 | Not Cancer Driver | No | 136 | 0.131 | 78 | 14 | 0.179 | 41 |
AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0034599 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0034599 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
BRF2 | BRF2 | Q9HAW0 | Transcription factor IIIB 50 kDa subunit | chr8 | GO:0034599 | Not Cancer Driver | No | 40 | 0.095 | 138 | 13 | 0.094 | 0 |
BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:0034599 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
CAMKK2 | CAMKK2 | Q96RR4 | Calcium/calmodulin-dependent protein kinase kinase 2 | chr12 | GO:0034599 | Not Cancer Driver | No | 65 | 0.111 | 281 | 35 | 0.125 | 0 |
CCS | CCS | O14618 | Copper chaperone for superoxide dismutase | chr11 | GO:0034599 | Not Cancer Driver | No | 28 | 0.102 | 105 | 10 | 0.095 | 0 |
CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0034599 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0034599 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
CHCHD2 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | GO:0034599 | Not Cancer Driver | No | 24 | 0.159 | 114 | 21 | 0.184 | 1 |
CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0034599 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
CPEB2_ENST00000507071 | CPEB2 | Q7Z5Q1 | Cytoplasmic polyadenylation element-binding protein 2 | chr4 | GO:0034599 | Not Cancer Driver | No | 66 | 0.112 | 269 | 17 | 0.063 | 0 |
CRYGD | CRYGD | P07320 | Gamma-crystallin D | chr2 | GO:0034599 | Not Cancer Driver | No | 28 | 0.161 | 0 | 0 | 0.0 | 6 |
CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0034599 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0034599 | Not Cancer Driver | No | 193 | 0.135 | 114 | 11 | 0.096 | 0 |
DHRS2_ENST00000250383 | DHRS2 | Q13268 | Dehydrogenase/reductase SDR family member 2, mitochondrial | chr14 | GO:0034599 | Not Cancer Driver | No | 47 | 0.168 | 0 | 0 | 0.0 | 0 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | GO:0034599 | Not Cancer Driver | No | 104 | 0.114 | 284 | 33 | 0.116 | 0 |
EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0034599 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0034599 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0034599 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
EIF2S1 | EIF2S1 | P05198 | Eukaryotic translation initiation factor 2 subunit 1 | chr14 | GO:0034599 | Not Cancer Driver | No | 35 | 0.111 | 59 | 6 | 0.102 | 0 |
ERMP1 | ERMP1 | Q7Z2K6 | Endoplasmic reticulum metallopeptidase 1 | chr9 | GO:0034599 | Not Cancer Driver | No | 80 | 0.088 | 93 | 4 | 0.043 | 0 |
ERN1 | ERN1 | O75460 | Serine/threonine-protein kinase/endoribonuclease IRE1 | chr17 | GO:0034599 | Not Cancer Driver | No | 125 | 0.128 | 250 | 28 | 0.112 | 0 |
ETV5_ENST00000434744 | ETV5 | P41161 | ETS translocation variant 5 | chr3 | GO:0034599 | Census, Compendium | Yes | 92 | 0.18 | 299 | 52 | 0.174 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0034599 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
FABP1 | FABP1 | P07148 | Fatty acid-binding protein, liver | chr2 | GO:0034599 | Not Cancer Driver | No | 34 | 0.268 | 0 | 0 | 0.0 | 0 |
FANCC | FANCC | Q00597 | Fanconi anemia group C protein | chr9 | GO:0034599 | Census, Compendium | Yes | 66 | 0.118 | 13 | 1 | 0.077 | 3 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | GO:0034599 | Census, Compendium | Yes | 176 | 0.121 | 181 | 14 | 0.077 | 3 |
FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0034599 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | GO:0034599 | Not Cancer Driver | No | 45 | 0.118 | 245 | 33 | 0.135 | 0 |
FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0034599 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0034599 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
FXN | FXN | Q16595 | Frataxin, mitochondrial | chr9 | GO:0034599 | Not Cancer Driver | No | 16 | 0.076 | 73 | 0 | 0.0 | 8 |
G6PD_ENST00000621232 | G6PD | P11413 | Glucose-6-phosphate 1-dehydrogenase | chrX | GO:0034599 | Not Cancer Driver | No | 86 | 0.167 | 28 | 3 | 0.107 | 58 |
GJB2_ENST00000382848 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0034599 | Not Cancer Driver | No | 34 | 0.15 | 0 | 0 | 0.0 | 46 |
GLRX2_ENST00000367439 | GLRX2 | Q9NS18 | Glutaredoxin-2, mitochondrial | chr1 | GO:0034599 | Not Cancer Driver | No | 12 | 0.073 | 10 | 1 | 0.1 | 0 |
GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0034599 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
GPX5 | GPX5 | O75715 | Epididymal secretory glutathione peroxidase | chr6 | GO:0034599 | Not Cancer Driver | No | 74 | 0.335 | 9 | 4 | 0.444 | 0 |
GPX7 | GPX7 | Q96SL4 | Glutathione peroxidase 7 | chr1 | GO:0034599 | Not Cancer Driver | No | 24 | 0.128 | 6 | 1 | 0.167 | 0 |
GPX8 | GPX8 | Q8TED1 | Probable glutathione peroxidase 8 | chr5 | GO:0034599 | Not Cancer Driver | No | 21 | 0.1 | 4 | 1 | 0.25 | 0 |
GSR | GSR | P00390 | Glutathione reductase, mitochondrial | chr8 | GO:0034599 | Not Cancer Driver | No | 53 | 0.102 | 55 | 5 | 0.091 | 1 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0034599 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0034599 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0034599 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0034599 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0034599 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
IL18BP_ENST00000337131 | IL18BP | O95998 | Interleukin-18-binding protein | chr11 | GO:0034599 | Not Cancer Driver | No | 16 | 0.082 | 50 | 6 | 0.12 | 0 |
IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0034599 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
IMPACT | IMPACT | Q9P2X3 | Protein IMPACT | chr18 | GO:0034599 | Not Cancer Driver | No | 49 | 0.153 | 84 | 12 | 0.143 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:0034599 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0034599 | Not Cancer Driver | No | 189 | 0.115 | 1278 | 142 | 0.111 | 2 |
KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0034599 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
KLF2 | KLF2 | Q9Y5W3 | Krueppel-like factor 2 | chr19 | GO:0034599 | Not Cancer Driver | No | 13 | 0.037 | 280 | 4 | 0.014 | 0 |
LONP1 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | GO:0034599 | Not Cancer Driver | No | 99 | 0.103 | 175 | 15 | 0.086 | 10 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0034599 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | GO:0034599 | Not Cancer Driver | No | 22 | 0.182 | 24 | 1 | 0.042 | 0 |
MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0034599 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
MAPK13 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0034599 | Not Cancer Driver | No | 51 | 0.14 | 50 | 15 | 0.3 | 0 |
MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0034599 | Census, Compendium | Yes | 62 | 0.172 | 2 | 0 | 0.0 | 7 |
MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0034599 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
MAPK7 | MAPK7 | Q13164 | Mitogen-activated protein kinase 7 | chr17 | GO:0034599 | Not Cancer Driver | No | 92 | 0.113 | 490 | 50 | 0.102 | 0 |
MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0034599 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
MAPK9 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0034599 | Not Cancer Driver | No | 59 | 0.139 | 90 | 8 | 0.089 | 0 |
MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0034599 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
MGAT3 | MGAT3 | Q09327 | Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | chr22 | GO:0034599 | Not Cancer Driver | No | 105 | 0.197 | 130 | 27 | 0.208 | 0 |
MGST1_ENST00000396210 | MGST1 | P10620 | Microsomal glutathione S-transferase 1 | chr12 | GO:0034599 | Not Cancer Driver | No | 26 | 0.168 | 0 | 0 | 0.0 | 0 |
MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0034599 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0034599 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
MPV17 | MPV17 | P39210 | Protein Mpv17 | chr2 | GO:0034599 | Not Cancer Driver | No | 21 | 0.119 | 0 | 0 | 0.0 | 16 |
MSRA | MSRA | Q9UJ68 | Mitochondrial peptide methionine sulfoxide reductase | chr8 | GO:0034599 | Not Cancer Driver | No | 39 | 0.166 | 81 | 14 | 0.173 | 0 |
MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0034599 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0034599 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
NET1 | NET1 | Q7Z628 | Neuroepithelial cell-transforming gene 1 protein | chr10 | GO:0034599 | Not Cancer Driver | No | 60 | 0.101 | 294 | 37 | 0.126 | 0 |
NFE2L1 | NFE2L1 | Q14494 | Endoplasmic reticulum membrane sensor NFE2L1 | chr17 | GO:0034599 | Not Cancer Driver | No | 65 | 0.084 | 511 | 32 | 0.063 | 0 |
NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0034599 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
NME8_ENST00000440017 | NME8 | Q8N427 | Thioredoxin domain-containing protein 3 | chr7 | GO:0034599 | Not Cancer Driver | No | 178 | 0.303 | 87 | 44 | 0.506 | 0 |
NQO1 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0034599 | Not Cancer Driver | No | 21 | 0.077 | 10 | 1 | 0.1 | 0 |
NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0034599 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
NUDT2_ENST00000346365 | NUDT2 | P50583 | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | chr9 | GO:0034599 | Not Cancer Driver | No | 16 | 0.109 | 24 | 1 | 0.042 | 0 |
OSER1 | OSER1 | Q9NX31 | Oxidative stress-responsive serine-rich protein 1 | chr20 | GO:0034599 | Not Cancer Driver | No | 32 | 0.11 | 221 | 28 | 0.127 | 0 |
OXR1 | OXR1 | Q8N573 | Oxidation resistance protein 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 126 | 0.144 | 544 | 76 | 0.14 | 0 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0034599 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0034599 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0034599 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0034599 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
PDGFD | PDGFD | Q9GZP0 | Platelet-derived growth factor D | chr11 | GO:0034599 | Not Cancer Driver | No | 85 | 0.23 | 37 | 13 | 0.351 | 0 |
PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0034599 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
PDK2 | PDK2 | Q15119 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | chr17 | GO:0034599 | Not Cancer Driver | No | 45 | 0.111 | 35 | 4 | 0.114 | 0 |
PENK_ENST00000451791 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0034599 | Not Cancer Driver | No | 109 | 0.408 | 142 | 62 | 0.437 | 0 |
PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0034599 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0034599 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
PLEKHA1 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0034599 | Not Cancer Driver | No | 61 | 0.151 | 191 | 32 | 0.168 | 0 |
PNPT1 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0034599 | Not Cancer Driver | No | 86 | 0.11 | 115 | 10 | 0.087 | 2 |
PPARGC1A | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0034599 | Not Cancer Driver | No | 181 | 0.227 | 609 | 148 | 0.243 | 0 |
PPARGC1B | PPARGC1B | Q86YN6 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta | chr5 | GO:0034599 | Not Cancer Driver | No | 125 | 0.122 | 845 | 99 | 0.117 | 0 |
PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0034599 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:0034599 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | GO:0034599 | Not Cancer Driver | No | 24 | 0.121 | 30 | 4 | 0.133 | 0 |
PRDX3 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0034599 | Not Cancer Driver | No | 23 | 0.09 | 23 | 3 | 0.13 | 0 |
PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0034599 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0034599 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0034599 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0034599 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0034599 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
PRKRA | PRKRA | O75569 | Interferon-inducible double-stranded RNA-dependent protein kinase activator A | chr2 | GO:0034599 | Not Cancer Driver | No | 41 | 0.131 | 104 | 12 | 0.115 | 1 |
PRR5L | PRR5L | Q6MZQ0 | Proline-rich protein 5-like | chr11 | GO:0034599 | Not Cancer Driver | No | 57 | 0.155 | 108 | 12 | 0.111 | 0 |
PTPRK_ENST00000368215 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0034599 | Census, Compendium | Yes | 292 | 0.203 | 302 | 57 | 0.189 | 0 |
PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | GO:0034599 | Not Cancer Driver | No | 62 | 0.105 | 341 | 24 | 0.07 | 0 |
PYCR1_ENST00000329875 | PYCR1 | P32322 | Pyrroline-5-carboxylate reductase 1, mitochondrial | chr17 | GO:0034599 | Not Cancer Driver | No | 31 | 0.097 | 67 | 10 | 0.149 | 9 |
PYCR2 | PYCR2 | Q96C36 | Pyrroline-5-carboxylate reductase 2 | chr1 | GO:0034599 | Not Cancer Driver | No | 31 | 0.097 | 41 | 3 | 0.073 | 2 |
PYROXD1 | PYROXD1 | Q8WU10 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | chr12 | GO:0034599 | Not Cancer Driver | No | 54 | 0.108 | 34 | 2 | 0.059 | 2 |
RAD52 | RAD52 | P43351 | DNA repair protein RAD52 homolog | chr12 | GO:0034599 | Not Cancer Driver | No | 41 | 0.098 | 251 | 30 | 0.12 | 0 |
RBM11 | RBM11 | P57052 | Splicing regulator RBM11 | chr21 | GO:0034599 | Not Cancer Driver | No | 67 | 0.238 | 124 | 38 | 0.306 | 0 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0034599 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | GO:0034599 | Not Cancer Driver | No | 52 | 0.265 | 19 | 2 | 0.105 | 0 |
RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0034599 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | GO:0034599 | Not Cancer Driver | No | 66 | 0.127 | 295 | 39 | 0.132 | 0 |
ROMO1_ENST00000397416 | ROMO1 | P60602 | Reactive oxygen species modulator 1 | chr20 | GO:0034599 | Not Cancer Driver | No | 9 | 0.114 | 0 | 0 | 0.0 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0034599 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
RWDD1 | RWDD1 | Q9H446 | RWD domain-containing protein 1 | chr6 | GO:0034599 | Not Cancer Driver | No | 28 | 0.115 | 168 | 19 | 0.113 | 0 |
SELENOS | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0034599 | Not Cancer Driver | No | 7 | 0.037 | 122 | 6 | 0.049 | 0 |
SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0034599 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0034599 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:0034599 | Census, Compendium | Yes | 96 | 0.19 | 281 | 51 | 0.181 | 0 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0034599 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0034599 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
SLC25A24 | SLC25A24 | Q6NUK1 | Calcium-binding mitochondrial carrier protein SCaMC-1 | chr1 | GO:0034599 | Not Cancer Driver | No | 40 | 0.084 | 21 | 2 | 0.095 | 2 |
SLC4A11_ENST00000539553 | SLC4A11 | Q8NBS3 | Solute carrier family 4 member 11 | chr20 | GO:0034599 | Not Cancer Driver | No | 159 | 0.182 | 69 | 10 | 0.145 | 42 |
SLC7A11 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0034599 | Not Cancer Driver | No | 70 | 0.14 | 15 | 2 | 0.133 | 0 |
SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0034599 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0034599 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0034599 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0034599 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
SRXN1 | SRXN1 | Q9BYN0 | Sulfiredoxin-1 | chr20 | GO:0034599 | Not Cancer Driver | No | 15 | 0.109 | 48 | 2 | 0.042 | 0 |
STAT6_ENST00000543873 | STAT6 | P42226 | Signal transducer and activator of transcription 6 | chr12 | GO:0034599 | Census, Compendium | Yes | 106 | 0.125 | 325 | 44 | 0.135 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | GO:0034599 | Not Cancer Driver | No | 77 | 0.133 | 456 | 63 | 0.138 | 0 |
STAU2 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0034599 | Not Cancer Driver | No | 68 | 0.119 | 486 | 54 | 0.111 | 0 |
STX2 | STX2 | P32856 | Syntaxin-2 | chr12 | GO:0034599 | Not Cancer Driver | No | 43 | 0.149 | 140 | 25 | 0.179 | 0 |
STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | GO:0034599 | Not Cancer Driver | No | 50 | 0.168 | 152 | 20 | 0.132 | 0 |
SUMO4 | SUMO4 | Q6EEV6 | Small ubiquitin-related modifier 4 | chr6 | GO:0034599 | Not Cancer Driver | No | 7 | 0.074 | 69 | 4 | 0.058 | 0 |
TMEM161A | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | GO:0034599 | Not Cancer Driver | No | 49 | 0.102 | 22 | 8 | 0.364 | 0 |
TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0034599 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
TP53INP1 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 32 | 0.133 | 134 | 20 | 0.149 | 0 |
TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | GO:0034599 | Not Cancer Driver | No | 33 | 0.116 | 234 | 29 | 0.124 | 8 |
TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0034599 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
TRPA1 | TRPA1 | O75762 | Transient receptor potential cation channel subfamily A member 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 324 | 0.29 | 62 | 14 | 0.226 | 1 |
TRPM2_ENST00000397928 | TRPM2 | O94759 | Transient receptor potential cation channel subfamily M member 2 | chr21 | GO:0034599 | Not Cancer Driver | No | 286 | 0.19 | 266 | 44 | 0.165 | 0 |
UCP1 | UCP1 | P25874 | Mitochondrial brown fat uncoupling protein 1 | chr4 | GO:0034599 | Not Cancer Driver | No | 43 | 0.14 | 1 | 0 | 0.0 | 0 |
VKORC1L1_ENST00000360768 | VKORC1L1 | Q8N0U8 | Vitamin K epoxide reductase complex subunit 1-like protein 1 | chr7 | GO:0034599 | Not Cancer Driver | No | 20 | 0.114 | 0 | 0 | 0.0 | 0 |
VRK2 | VRK2 | Q86Y07 | Serine/threonine-protein kinase VRK2 | chr2 | GO:0034599 | Not Cancer Driver | No | 63 | 0.124 | 126 | 15 | 0.119 | 0 |
ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0034599 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
ZFAND1 | ZFAND1 | Q8TCF1 | AN1-type zinc finger protein 1 | chr8 | GO:0034599 | Not Cancer Driver | No | 34 | 0.127 | 30 | 7 | 0.233 | 0 |
ZNF277 | ZNF277 | Q9NRM2 | Zinc finger protein 277 | chr7 | GO:0034599 | Not Cancer Driver | No | 59 | 0.131 | 79 | 15 | 0.19 | 0 |
ZNF580_ENST00000545125 | ZNF580 | Q9UK33 | Zinc finger protein 580 | chr19 | GO:0034599 | Not Cancer Driver | No | 8 | 0.047 | 153 | 8 | 0.052 | 0 |