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Total number of protein in "GO:0034329" GO term:  145

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0034329 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0034329 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0034329 Not Cancer Driver No 108 0.121 195 30 0.154 6
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0034329 Not Cancer Driver No 227 0.254 131 29 0.221 9
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0034329 Not Cancer Driver No 123 0.137 135 13 0.096 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 GO:0034329 Census Yes 248 0.136 1247 180 0.144 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:0034329 Compendium Yes 45 0.084 307 13 0.042 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0034329 Not Cancer Driver No 770 0.195 2844 566 0.199 4
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0034329 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0034329 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0034329 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0034329 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0034329 Not Cancer Driver No 19 0.103 0 0 0.0 1
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0034329 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0034329 Census, Compendium Yes 146 0.115 603 69 0.114 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 GO:0034329 Not Cancer Driver No 40 0.14 41 2 0.049 0
CBLN4 CBLN4 Q9NTU7 Cerebellin-4 chr20 GO:0034329 Not Cancer Driver No 62 0.308 20 10 0.5 0
CD9 CD9 P21926 CD9 antigen chr12 GO:0034329 Not Cancer Driver No 22 0.096 0 0 0.0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0034329 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0034329 Not Cancer Driver No 144 0.184 305 55 0.18 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0034329 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN10 CLDN10 P78369 Claudin-10 chr13 GO:0034329 Not Cancer Driver No 51 0.224 4 1 0.25 2
CLDN11 CLDN11 O75508 Claudin-11 chr3 GO:0034329 Not Cancer Driver No 30 0.145 0 0 0.0 0
CLDN12_ENST00000394605 CLDN12 P56749 Claudin-12 chr7 GO:0034329 Not Cancer Driver No 37 0.152 0 0 0.0 0
CLDN14_ENST00000399135 CLDN14 O95500 Claudin-14 chr21 GO:0034329 Not Cancer Driver No 33 0.138 34 3 0.088 5
CLDN15 CLDN15 P56746 Claudin-15 chr7 GO:0034329 Not Cancer Driver No 30 0.132 2 0 0.0 0
CLDN17 CLDN17 P56750 Claudin-17 chr21 GO:0034329 Not Cancer Driver No 59 0.263 6 3 0.5 0
CLDN18 CLDN18 P56856 Claudin-18 chr3 GO:0034329 Not Cancer Driver No 44 0.169 21 5 0.238 0
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0034329 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLDN20 CLDN20 P56880 Claudin-20 chr6 GO:0034329 Not Cancer Driver No 21 0.096 19 3 0.158 0
CLDN22 CLDN22 Q8N7P3 Claudin-22 chr4 GO:0034329 Not Cancer Driver No 30 0.136 15 1 0.067 0
CLDN23 CLDN23 Q96B33 Claudin-23 chr8 GO:0034329 Not Cancer Driver No 16 0.055 92 6 0.065 0
CLDN24 CLDN24 A6NM45 Putative claudin-24 chr4 GO:0034329 Not Cancer Driver No 4 0.018 0 0 0.0 0
CLDN25 CLDN25 C9JDP6 Putative claudin-25 chr11 GO:0034329 Not Cancer Driver No 38 0.166 0 0 0.0 0
CLDN2_ENST00000336803 CLDN2 P57739 Claudin-2 chrX GO:0034329 Not Cancer Driver No 33 0.143 13 0 0.0 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0034329 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0034329 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0034329 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLDN6 CLDN6 P56747 Claudin-6 chr16 GO:0034329 Not Cancer Driver No 52 0.236 0 0 0.0 0
CLDN7_ENST00000397317 CLDN7 O95471 Claudin-7 chr17 GO:0034329 Not Cancer Driver No 18 0.085 2 0 0.0 0
CLDN8 CLDN8 P56748 Claudin-8 chr21 GO:0034329 Not Cancer Driver No 40 0.178 5 2 0.4 0
CLDN9 CLDN9 O95484 Claudin-9 chr16 GO:0034329 Not Cancer Driver No 30 0.138 6 0 0.0 0
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0034329 Not Cancer Driver No 173 0.125 141 15 0.106 6
COL17A1 COL17A1 Q9UMD9 Collagen alpha-1(XVII) chain chr10 GO:0034329 Not Cancer Driver No 196 0.131 1275 164 0.129 5
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0034329 Not Cancer Driver No 85 0.177 37 7 0.189 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0034329 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0034329 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 GO:0034329 Not Cancer Driver No 78 0.142 465 56 0.12 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0034329 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0034329 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0034329 Not Cancer Driver No 230 0.12 1119 135 0.121 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0034329 Not Cancer Driver No 104 0.114 284 33 0.116 0
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 GO:0034329 Not Cancer Driver No 298 0.274 695 207 0.298 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0034329 Not Cancer Driver No 186 0.176 119 17 0.143 7
ESAM ESAM Q96AP7 Endothelial cell-selective adhesion molecule chr11 GO:0034329 Not Cancer Driver No 54 0.138 154 30 0.195 0
FBF1_ENST00000586717 FBF1 Q8TES7 Fas-binding factor 1 chr17 GO:0034329 Not Cancer Driver No 125 0.11 1066 116 0.109 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0034329 Not Cancer Driver No 28 0.098 10 0 0.0 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0034329 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0034329 Not Cancer Driver No 70 0.286 96 33 0.344 2
FRMPD2 FRMPD2 Q68DX3 FERM and PDZ domain-containing protein 2 chr10 GO:0034329 Not Cancer Driver No 254 0.194 479 106 0.221 0
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0034329 Not Cancer Driver No 175 0.384 58 31 0.534 6
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0034329 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0034329 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0034329 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0034329 Not Cancer Driver No 188 0.403 19 13 0.684 11
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0034329 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0034329 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJB1_ENST00000647424 GJB1 P08034 Gap junction beta-1 protein chrX GO:0034329 Not Cancer Driver No 34 0.12 23 7 0.304 189
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0034329 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0034329 Not Cancer Driver No 42 0.161 12 4 0.333 4
GJC1_ENST00000590758 GJC1 P36383 Gap junction gamma-1 protein chr17 GO:0034329 Not Cancer Driver No 63 0.159 150 30 0.2 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 GO:0034329 Not Cancer Driver No 5 0.017 79 0 0.0 0
GNPAT GNPAT O15228 Dihydroxyacetone phosphate acyltransferase chr1 GO:0034329 Not Cancer Driver No 86 0.126 6 3 0.5 3
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0034329 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0034329 Not Cancer Driver No 350 0.348 155 35 0.226 3
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0034329 Not Cancer Driver No 158 0.131 565 89 0.158 0
ILDR1_ENST00000344209 ILDR1 Q86SU0 Immunoglobulin-like domain-containing receptor 1 chr3 GO:0034329 Not Cancer Driver No 112 0.205 260 66 0.254 1
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0034329 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGB4 ITGB4 P16144 Integrin beta-4 chr17 GO:0034329 Not Cancer Driver No 248 0.136 753 86 0.114 14
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0034329 Not Cancer Driver No 50 0.161 62 11 0.177 2
JUP JUP P14923 Junction plakoglobin chr17 GO:0034329 Not Cancer Driver No 112 0.15 241 37 0.154 0
LAMC1 LAMC1 P11047 Laminin subunit gamma-1 chr1 GO:0034329 Not Cancer Driver No 232 0.144 562 94 0.167 0
LGI2 LGI2 Q8N0V4 Leucine-rich repeat LGI family member 2 chr4 GO:0034329 Not Cancer Driver No 96 0.176 0 0 0.0 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0034329 Not Cancer Driver No 233 0.122 265 28 0.106 11
LRRC4 LRRC4 Q9HBW1 Leucine-rich repeat-containing protein 4 chr7 GO:0034329 Not Cancer Driver No 117 0.179 110 14 0.127 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 GO:0034329 Not Cancer Driver No 89 0.137 330 42 0.127 0
MARVELD2_ENST00000325631 MARVELD2 Q8N4S9 MARVEL domain-containing protein 2 chr5 GO:0034329 Not Cancer Driver No 74 0.133 251 36 0.143 0
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0034329 Not Cancer Driver No 40 0.1 179 10 0.056 0
MICALL2 MICALL2 Q8IY33 MICAL-like protein 2 chr7 GO:0034329 Not Cancer Driver No 110 0.122 675 88 0.13 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 GO:0034329 Not Cancer Driver No 287 0.139 858 122 0.142 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 GO:0034329 Not Cancer Driver No 132 0.229 199 72 0.362 0
MYO9A MYO9A B2RTY4 Unconventional myosin-IXa chr15 GO:0034329 Not Cancer Driver No 323 0.127 970 131 0.135 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0034329 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0034329 Not Cancer Driver No 91 0.109 300 19 0.063 0
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0034329 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0034329 Not Cancer Driver No 47 0.118 118 9 0.076 0
OCEL1 OCEL1 Q9H607 Occludin/ELL domain-containing protein 1 chr19 GO:0034329 Not Cancer Driver No 25 0.095 193 21 0.109 0
OCLN OCLN Q16625 Occludin chr5 GO:0034329 Not Cancer Driver No 54 0.103 244 21 0.086 1
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0034329 Not Cancer Driver No 122 0.152 302 42 0.139 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0034329 Compendium Yes 89 0.17 242 49 0.202 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0034329 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PATJ PATJ Q8NI35 InaD-like protein chr1 GO:0034329 Not Cancer Driver No 261 0.145 918 142 0.155 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0034329 Not Cancer Driver No 85 0.098 272 22 0.081 0
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 GO:0034329 Not Cancer Driver No 222 0.127 1232 150 0.122 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0034329 Not Cancer Driver No 2 0.003 153 2 0.013 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0034329 Not Cancer Driver No 74 0.132 216 29 0.134 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0034329 Not Cancer Driver No 98 0.147 360 60 0.167 1
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 GO:0034329 Not Cancer Driver No 123 0.125 415 48 0.116 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0034329 Not Cancer Driver No 176 0.2 434 98 0.226 8
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 GO:0034329 Not Cancer Driver No 72 0.09 357 22 0.062 0
PLEC PLEC Q15149 Plectin chr8 GO:0034329 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0034329 Not Cancer Driver No 228 0.107 684 67 0.098 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0034329 Not Cancer Driver No 273 0.149 304 35 0.115 0
POF1B_ENST00000262753 POF1B Q8WVV4 Protein POF1B chrX GO:0034329 Not Cancer Driver No 154 0.261 391 104 0.266 1
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0034329 Not Cancer Driver No 94 0.14 154 22 0.143 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0034329 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0034329 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0034329 Not Cancer Driver No 204 0.168 137 34 0.248 0
RAB13 RAB13 P51153 Ras-related protein Rab-13 chr1 GO:0034329 Not Cancer Driver No 19 0.094 40 0 0.0 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0034329 Not Cancer Driver No 18 0.103 34 6 0.176 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0034329 Not Cancer Driver No 63 0.121 194 27 0.139 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0034329 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0034329 Not Cancer Driver No 30 0.155 53 7 0.132 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0034329 Not Cancer Driver No 20 0.095 10 0 0.0 0
SH3BP1 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 GO:0034329 Not Cancer Driver No 57 0.081 430 31 0.072 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0034329 Not Cancer Driver No 40 0.094 139 0 0.0 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0034329 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0034329 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0034329 Not Cancer Driver No 44 0.087 443 42 0.095 0
STRN STRN O43815 Striatin chr2 GO:0034329 Census, Compendium Yes 97 0.124 348 43 0.124 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0034329 Not Cancer Driver No 191 0.155 666 102 0.153 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0034329 Not Cancer Driver No 156 0.131 60 9 0.15 11
TESK2 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 GO:0034329 Not Cancer Driver No 77 0.135 242 43 0.178 0
THSD1 THSD1 Q9NS62 Thrombospondin type-1 domain-containing protein 1 chr13 GO:0034329 Not Cancer Driver No 161 0.189 427 86 0.201 2
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0034329 Not Cancer Driver No 24 0.149 5 0 0.0 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 GO:0034329 Not Cancer Driver No 62 0.13 268 19 0.071 0
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 GO:0034329 Not Cancer Driver No 107 0.198 18 2 0.111 0
VCL VCL P18206 Vinculin chr10 GO:0034329 Not Cancer Driver No 114 0.101 673 80 0.119 2
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 GO:0034329 Not Cancer Driver No 57 0.14 68 11 0.162 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0034329 Not Cancer Driver No 66 0.109 30 7 0.233 2
WHAMM WHAMM Q8TF30 WASP homolog-associated protein with actin, membranes and microtubules chr15 GO:0034329 Not Cancer Driver No 59 0.073 399 38 0.095 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0034329 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0034329 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0034329 Not Cancer Driver No 93 0.266 18 9 0.5 4
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0034329 Not Cancer Driver No 26 0.044 415 14 0.034 0