Total number of protein in "GO:0032989" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0032989 | Census, Compendium | Yes | 55 | 0.108 | 360 | 39 | 0.108 | 0 |
| ADARB1 | ADARB1 | P78563 | Double-stranded RNA-specific editase 1 | chr21 | GO:0032989 | Not Cancer Driver | No | 102 | 0.138 | 348 | 34 | 0.098 | 1 |
| ARC | ARC | Q7LC44 | Activity-regulated cytoskeleton-associated protein | chr8 | GO:0032989 | Not Cancer Driver | No | 64 | 0.162 | 194 | 29 | 0.149 | 0 |
| ARHGAP35_ENST00000614079 | ARHGAP35 | Q9NRY4 | Rho GTPase-activating protein 35 | chr19 | GO:0032989 | Census, Compendium | Yes | 255 | 0.17 | 409 | 58 | 0.142 | 0 |
| B4GALT5 | B4GALT5 | O43286 | Beta-1,4-galactosyltransferase 5 | chr20 | GO:0032989 | Not Cancer Driver | No | 53 | 0.137 | 20 | 1 | 0.05 | 0 |
| B4GALT6 | B4GALT6 | Q9UBX8 | Beta-1,4-galactosyltransferase 6 | chr18 | GO:0032989 | Not Cancer Driver | No | 47 | 0.123 | 13 | 2 | 0.154 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0032989 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0032989 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| C12orf57 | C12orf57 | Q99622 | Protein C10 | chr12 | GO:0032989 | Not Cancer Driver | No | 13 | 0.103 | 29 | 1 | 0.034 | 1 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0032989 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDH11 | CDH11 | P55287 | Cadherin-11 | chr16 | GO:0032989 | Census, Compendium | Yes | 264 | 0.332 | 399 | 127 | 0.318 | 0 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0032989 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| CHRNB2 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0032989 | Not Cancer Driver | No | 92 | 0.183 | 23 | 2 | 0.087 | 2 |
| COL4A3BP_ENST00000261415 | CERT1 | Q9Y5P4 | Ceramide transfer protein | chr5 | GO:0032989 | Not Cancer Driver | No | 73 | 0.117 | 215 | 23 | 0.107 | 2 |
| CSPG5 | CSPG5 | O95196 | Chondroitin sulfate proteoglycan 5 | chr3 | GO:0032989 | Not Cancer Driver | No | 75 | 0.133 | 397 | 46 | 0.116 | 0 |
| CTNND2 | CTNND2 | Q9UQB3 | Catenin delta-2 | chr5 | GO:0032989 | Census | Yes | 386 | 0.315 | 837 | 254 | 0.303 | 0 |
| DCC | DCC | P43146 | Netrin receptor DCC | chr18 | GO:0032989 | Census, Compendium | Yes | 530 | 0.366 | 631 | 215 | 0.341 | 2 |
| DCLK1 | DCLK1 | O15075 | Serine/threonine-protein kinase DCLK1 | chr13 | GO:0032989 | Not Cancer Driver | No | 209 | 0.282 | 252 | 77 | 0.306 | 0 |
| DIP2A | DIP2A | Q14689 | Disco-interacting protein 2 homolog A | chr21 | GO:0032989 | Not Cancer Driver | No | 204 | 0.13 | 396 | 53 | 0.134 | 0 |
| DLG4_ENST00000399506 | DLG4 | P78352 | Disks large homolog 4 | chr17 | GO:0032989 | Not Cancer Driver | No | 116 | 0.16 | 232 | 55 | 0.237 | 0 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0032989 | Not Cancer Driver | No | 67 | 0.091 | 212 | 23 | 0.108 | 7 |
| DOCK10 | DOCK10 | Q96BY6 | Dedicator of cytokinesis protein 10 | chr2 | GO:0032989 | Not Cancer Driver | No | 368 | 0.168 | 409 | 58 | 0.142 | 0 |
| DRAXIN | DRAXIN | Q8NBI3 | Draxin | chr1 | GO:0032989 | Not Cancer Driver | No | 61 | 0.175 | 249 | 48 | 0.193 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0032989 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| ECE1 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0032989 | Not Cancer Driver | No | 118 | 0.153 | 99 | 26 | 0.263 | 1 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0032989 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0032989 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0032989 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB1 | EPHB1 | P54762 | Ephrin type-B receptor 1 | chr3 | GO:0032989 | Not Cancer Driver | No | 316 | 0.321 | 67 | 17 | 0.254 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0032989 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| EPHB3 | EPHB3 | P54753 | Ephrin type-B receptor 3 | chr3 | GO:0032989 | Not Cancer Driver | No | 155 | 0.155 | 137 | 16 | 0.117 | 0 |
| EPHB6_ENST00000422643 | EPHB6 | O15197 | Ephrin type-B receptor 6 | chr7 | GO:0032989 | Not Cancer Driver | No | 227 | 0.222 | 246 | 45 | 0.183 | 0 |
| FBXO45 | FBXO45 | P0C2W1 | F-box/SPRY domain-containing protein 1 | chr3 | GO:0032989 | Not Cancer Driver | No | 28 | 0.098 | 10 | 0 | 0.0 | 0 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0032989 | Not Cancer Driver | No | 66 | 0.168 | 277 | 49 | 0.177 | 0 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | GO:0032989 | Not Cancer Driver | No | 25 | 0.164 | 6 | 0 | 0.0 | 0 |
| GLI2_ENST00000361492 | GLI2 | P10070 | Zinc finger protein GLI2 | chr2 | GO:0032989 | Not Cancer Driver | No | 287 | 0.181 | 1403 | 244 | 0.174 | 2 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0032989 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0032989 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0032989 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
| IGF2BP1 | IGF2BP1 | Q9NZI8 | Insulin-like growth factor 2 mRNA-binding protein 1 | chr17 | GO:0032989 | Not Cancer Driver | No | 141 | 0.244 | 298 | 80 | 0.268 | 0 |
| ISL1 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0032989 | Not Cancer Driver | No | 85 | 0.244 | 180 | 41 | 0.228 | 0 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | GO:0032989 | Not Cancer Driver | No | 254 | 0.246 | 97 | 27 | 0.278 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0032989 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0032989 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0032989 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MFF | MFF | Q9GZY8 | Mitochondrial fission factor | chr2 | GO:0032989 | Not Cancer Driver | No | 59 | 0.173 | 264 | 47 | 0.178 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0032989 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MYCBP2_ENST00000357337 | MYCBP2 | O75592 | E3 ubiquitin-protein ligase MYCBP2 | chr13 | GO:0032989 | Not Cancer Driver | No | 608 | 0.13 | 1398 | 189 | 0.135 | 0 |
| MYH14_ENST00000596571 | MYH14 | Q7Z406 | Myosin-14 | chr19 | GO:0032989 | Not Cancer Driver | No | 275 | 0.138 | 1215 | 169 | 0.139 | 5 |
| NDEL1 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | GO:0032989 | Not Cancer Driver | No | 32 | 0.093 | 202 | 16 | 0.079 | 0 |
| NEFH | NEFH | P12036 | Neurofilament heavy polypeptide | chr22 | GO:0032989 | Compendium | Yes | 114 | 0.111 | 871 | 106 | 0.122 | 0 |
| NFIB_ENST00000380959 | NFIB | O00712 | Nuclear factor 1 B-type | chr9 | GO:0032989 | Census | Yes | 63 | 0.15 | 254 | 36 | 0.142 | 3 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0032989 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
| NLGN1_ENST00000361589 | NLGN1 | Q8N2Q7 | Neuroligin-1 | chr3 | GO:0032989 | Not Cancer Driver | No | 214 | 0.248 | 248 | 61 | 0.246 | 4 |
| NPTX1 | NPTX1 | Q15818 | Neuronal pentraxin-1 | chr17 | GO:0032989 | Not Cancer Driver | No | 63 | 0.146 | 185 | 24 | 0.13 | 0 |
| NR2E1_ENST00000368986 | NR2E1 | Q9Y466 | Nuclear receptor subfamily 2 group E member 1 | chr6 | GO:0032989 | Not Cancer Driver | No | 75 | 0.195 | 57 | 6 | 0.105 | 0 |
| NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0032989 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0032989 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0032989 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NUBPL | NUBPL | Q8TB37 | Iron-sulfur protein NUBPL | chr14 | GO:0032989 | Not Cancer Driver | No | 32 | 0.1 | 49 | 1 | 0.02 | 2 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0032989 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0032989 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PAK6_ENST00000260404 | PAK6 | Q9NQU5 | Serine/threonine-protein kinase PAK 6 | chr15 | GO:0032989 | Not Cancer Driver | No | 82 | 0.12 | 398 | 52 | 0.131 | 0 |
| PANK2 | PANK2 | Q9BZ23 | Pantothenate kinase 2, mitochondrial | chr20 | GO:0032989 | Not Cancer Driver | No | 46 | 0.081 | 206 | 14 | 0.068 | 30 |
| PHACTR1 | PHACTR1 | Q9C0D0 | Phosphatase and actin regulator 1 | chr6 | GO:0032989 | Not Cancer Driver | No | 81 | 0.14 | 447 | 59 | 0.132 | 3 |
| PHOX2B | PHOX2B | Q99453 | Paired mesoderm homeobox protein 2B | chr4 | GO:0032989 | Census | Yes | 59 | 0.188 | 219 | 44 | 0.201 | 2 |
| PID1 | PID1 | Q7Z2X4 | PTB-containing, cubilin and LRP1-interacting protein | chr2 | GO:0032989 | Not Cancer Driver | No | 70 | 0.28 | 24 | 10 | 0.417 | 0 |
| PLEC | PLEC | Q15149 | Plectin | chr8 | GO:0032989 | Not Cancer Driver | No | 677 | 0.145 | 2130 | 272 | 0.128 | 2 |
| PLEKHO1 | PLEKHO1 | Q53GL0 | Pleckstrin homology domain-containing family O member 1 | chr1 | GO:0032989 | Not Cancer Driver | No | 55 | 0.134 | 341 | 46 | 0.135 | 0 |
| PLXNA4 | PLXNA4 | Q9HCM2 | Plexin-A4 | chr7 | GO:0032989 | Not Cancer Driver | No | 591 | 0.312 | 198 | 63 | 0.318 | 0 |
| PNPT1 | PNPT1 | Q8TCS8 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | chr2 | GO:0032989 | Not Cancer Driver | No | 86 | 0.11 | 115 | 10 | 0.087 | 2 |
| POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | GO:0032989 | Not Cancer Driver | No | 36 | 0.098 | 94 | 13 | 0.138 | 0 |
| POLG2 | POLG2 | Q9UHN1 | DNA polymerase subunit gamma-2, mitochondrial | chr17 | GO:0032989 | Not Cancer Driver | No | 64 | 0.132 | 46 | 4 | 0.087 | 3 |
| PRMT3 | PRMT3 | O60678 | Protein arginine N-methyltransferase 3 | chr11 | GO:0032989 | Not Cancer Driver | No | 68 | 0.128 | 52 | 9 | 0.173 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0032989 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0032989 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0032989 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| SEMA3A | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0032989 | Not Cancer Driver | No | 195 | 0.253 | 164 | 46 | 0.28 | 10 |
| SHANK1 | SHANK1 | Q9Y566 | SH3 and multiple ankyrin repeat domains protein 1 | chr19 | GO:0032989 | Not Cancer Driver | No | 288 | 0.133 | 1659 | 186 | 0.112 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | GO:0032989 | Not Cancer Driver | No | 37 | 0.089 | 96 | 2 | 0.021 | 4 |
| SLIRP | SLIRP | Q9GZT3 | SRA stem-loop-interacting RNA-binding protein, mitochondrial | chr14 | GO:0032989 | Not Cancer Driver | No | 7 | 0.064 | 41 | 3 | 0.073 | 0 |
| SNX1_ENST00000559844 | SNX1 | Q13596 | Sorting nexin-1 | chr15 | GO:0032989 | Not Cancer Driver | No | 61 | 0.117 | 214 | 25 | 0.117 | 0 |
| SNX2 | SNX2 | O60749 | Sorting nexin-2 | chr5 | GO:0032989 | Not Cancer Driver | No | 45 | 0.087 | 218 | 18 | 0.083 | 0 |
| SPTBN4_ENST00000598249 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | GO:0032989 | Not Cancer Driver | No | 312 | 0.122 | 866 | 103 | 0.119 | 0 |
| SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | GO:0032989 | Not Cancer Driver | No | 27 | 0.182 | 0 | 0 | 0.0 | 6 |
| SULT4A1 | SULT4A1 | Q9BR01 | Sulfotransferase 4A1 | chr22 | GO:0032989 | Not Cancer Driver | No | 46 | 0.162 | 17 | 2 | 0.118 | 0 |
| SUPV3L1 | SUPV3L1 | Q8IYB8 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | chr10 | GO:0032989 | Not Cancer Driver | No | 72 | 0.092 | 140 | 12 | 0.086 | 0 |
| SZT2_ENST00000634258 | SZT2 | Q5T011 | KICSTOR complex protein SZT2 | chr1 | GO:0032989 | Not Cancer Driver | No | 381 | 0.111 | 1292 | 161 | 0.125 | 1 |
| TAOK2 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0032989 | Not Cancer Driver | No | 191 | 0.155 | 666 | 102 | 0.153 | 0 |
| TCTN1_ENST00000551590 | TCTN1 | Q2MV58 | Tectonic-1 | chr12 | GO:0032989 | Not Cancer Driver | No | 63 | 0.107 | 47 | 6 | 0.128 | 0 |
| TPBG_ENST00000543496 | TPBG | Q13641 | Trophoblast glycoprotein | chr6 | GO:0032989 | Not Cancer Driver | No | 58 | 0.138 | 13 | 1 | 0.077 | 0 |
| TSKU_ENST00000333090 | TSKU | Q8WUA8 | Tsukushi | chr11 | GO:0032989 | Not Cancer Driver | No | 53 | 0.15 | 44 | 6 | 0.136 | 0 |
| WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | GO:0032989 | Not Cancer Driver | No | 63 | 0.113 | 445 | 49 | 0.11 | 0 |
| WASF2 | WASF2 | Q9Y6W5 | Wiskott-Aldrich syndrome protein family member 2 | chr1 | GO:0032989 | Not Cancer Driver | No | 61 | 0.122 | 400 | 43 | 0.107 | 0 |
| WASL | WASL | O00401 | Neural Wiskott-Aldrich syndrome protein | chr7 | GO:0032989 | Not Cancer Driver | No | 72 | 0.143 | 394 | 57 | 0.145 | 0 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0032989 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |