Total number of protein in "GO:0032508" GO term: 68
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0032508 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| ASCC3 | ASCC3 | Q8N3C0 | Activating signal cointegrator 1 complex subunit 3 | chr6 | GO:0032508 | Not Cancer Driver | No | 279 | 0.127 | 87 | 8 | 0.092 | 0 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0032508 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BLM | BLM | P54132 | Bloom syndrome protein | chr15 | GO:0032508 | Census | Yes | 153 | 0.108 | 667 | 70 | 0.105 | 8 |
| BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0032508 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
| CHD1 | CHD1 | O14646 | Chromodomain-helicase-DNA-binding protein 1 | chr5 | GO:0032508 | Not Cancer Driver | No | 172 | 0.101 | 975 | 109 | 0.112 | 4 |
| CHD1L | CHD1L | Q86WJ1 | Chromodomain-helicase-DNA-binding protein 1-like | chr1 | GO:0032508 | Not Cancer Driver | No | 98 | 0.109 | 225 | 30 | 0.133 | 0 |
| CHD2 | CHD2 | O14647 | Chromodomain-helicase-DNA-binding protein 2 | chr15 | GO:0032508 | Census, Compendium | Yes | 222 | 0.121 | 1051 | 136 | 0.129 | 2 |
| CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | GO:0032508 | Not Cancer Driver | No | 235 | 0.117 | 1015 | 122 | 0.12 | 18 |
| CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | GO:0032508 | Census, Compendium | Yes | 419 | 0.219 | 974 | 177 | 0.182 | 6 |
| CHD5 | CHD5 | Q8TDI0 | Chromodomain-helicase-DNA-binding protein 5 | chr1 | GO:0032508 | Not Cancer Driver | No | 365 | 0.187 | 931 | 183 | 0.197 | 0 |
| CHD6 | CHD6 | Q8TD26 | Chromodomain-helicase-DNA-binding protein 6 | chr20 | GO:0032508 | Not Cancer Driver | No | 393 | 0.145 | 1469 | 213 | 0.145 | 0 |
| CHD7 | CHD7 | Q9P2D1 | Chromodomain-helicase-DNA-binding protein 7 | chr8 | GO:0032508 | Not Cancer Driver | No | 464 | 0.155 | 1872 | 299 | 0.16 | 50 |
| CHD8_ENST00000643469 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0032508 | Not Cancer Driver | No | 328 | 0.127 | 1411 | 148 | 0.105 | 0 |
| CHD9_ENST00000398510 | CHD9 | Q3L8U1 | Chromodomain-helicase-DNA-binding protein 9 | chr16 | GO:0032508 | Not Cancer Driver | No | 301 | 0.104 | 1653 | 162 | 0.098 | 0 |
| CHTF18 | CHTF18 | Q8WVB6 | Chromosome transmission fidelity protein 18 homolog | chr16 | GO:0032508 | Not Cancer Driver | No | 114 | 0.117 | 503 | 56 | 0.111 | 0 |
| CHTF8_ENST00000398235 | CHTF8 | P0CG13 | Chromosome transmission fidelity protein 8 homolog | chr16 | GO:0032508 | Not Cancer Driver | No | 13 | 0.107 | 7 | 0 | 0.0 | 0 |
| DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | GO:0032508 | Not Cancer Driver | No | 82 | 0.111 | 91 | 15 | 0.165 | 0 |
| DDX11 | DDX11 | Q96FC9 | ATP-dependent DNA helicase DDX11 | chr12 | GO:0032508 | Not Cancer Driver | No | 154 | 0.159 | 280 | 55 | 0.196 | 1 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0032508 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0032508 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0032508 | Compendium | Yes | 182 | 0.143 | 331 | 42 | 0.127 | 0 |
| DNA2 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0032508 | Not Cancer Driver | No | 120 | 0.113 | 52 | 8 | 0.154 | 3 |
| DQX1_ENST00000393951 | DQX1 | Q8TE96 | ATP-dependent RNA helicase DQX1 | chr2 | GO:0032508 | Not Cancer Driver | No | 92 | 0.128 | 88 | 14 | 0.159 | 0 |
| DSCC1 | DSCC1 | Q9BVC3 | Sister chromatid cohesion protein DCC1 | chr8 | GO:0032508 | Not Cancer Driver | No | 28 | 0.071 | 41 | 4 | 0.098 | 0 |
| ERCC2 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0032508 | Census, Compendium | Yes | 150 | 0.197 | 5 | 0 | 0.0 | 35 |
| ERCC3 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | GO:0032508 | Census, Compendium | Yes | 92 | 0.118 | 208 | 22 | 0.106 | 2 |
| ERCC6L | ERCC6L | Q2NKX8 | DNA excision repair protein ERCC-6-like | chrX | GO:0032508 | Not Cancer Driver | No | 137 | 0.11 | 532 | 72 | 0.135 | 0 |
| FANCM | FANCM | Q8IYD8 | Fanconi anemia group M protein | chr14 | GO:0032508 | Not Cancer Driver | No | 268 | 0.131 | 898 | 128 | 0.143 | 0 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | GO:0032508 | Not Cancer Driver | No | 139 | 0.133 | 192 | 32 | 0.167 | 0 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | GO:0032508 | Not Cancer Driver | No | 85 | 0.182 | 352 | 65 | 0.185 | 0 |
| GTF2F2 | GTF2F2 | P13984 | General transcription factor IIF subunit 2 | chr13 | GO:0032508 | Not Cancer Driver | No | 20 | 0.08 | 112 | 9 | 0.08 | 0 |
| HELB | HELB | Q8NG08 | DNA helicase B | chr12 | GO:0032508 | Not Cancer Driver | No | 140 | 0.129 | 300 | 38 | 0.127 | 0 |
| HELQ | HELQ | Q8TDG4 | Helicase POLQ-like | chr4 | GO:0032508 | Not Cancer Driver | No | 134 | 0.122 | 273 | 19 | 0.07 | 0 |
| HFM1 | HFM1 | A2PYH4 | Probable ATP-dependent DNA helicase HFM1 | chr1 | GO:0032508 | Not Cancer Driver | No | 252 | 0.176 | 373 | 60 | 0.161 | 2 |
| IGHMBP2 | IGHMBP2 | P38935 | DNA-binding protein SMUBP-2 | chr11 | GO:0032508 | Not Cancer Driver | No | 136 | 0.137 | 354 | 53 | 0.15 | 31 |
| MCM8_ENST00000378896 | MCM8 | Q9UJA3 | DNA helicase MCM8 | chr20 | GO:0032508 | Not Cancer Driver | No | 94 | 0.112 | 188 | 19 | 0.101 | 1 |
| MCM9_ENST00000619706 | MCM9 | Q9NXL9 | DNA helicase MCM9 | chr6 | GO:0032508 | Not Cancer Driver | No | 56 | 0.049 | 523 | 13 | 0.025 | 0 |
| MCMDC2 | MCMDC2 | Q4G0Z9 | Minichromosome maintenance domain-containing protein 2 | chr8 | GO:0032508 | Not Cancer Driver | No | 98 | 0.144 | 0 | 0 | 0.0 | 0 |
| MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0032508 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
| NAV2 | NAV2 | Q8IVL1 | Neuron navigator 2 | chr11 | GO:0032508 | Not Cancer Driver | No | 367 | 0.148 | 1866 | 276 | 0.148 | 0 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0032508 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| PIF1_ENST00000559239 | PIF1 | Q9H611 | ATP-dependent DNA helicase PIF1 | chr15 | GO:0032508 | Not Cancer Driver | No | 54 | 0.084 | 209 | 11 | 0.053 | 0 |
| POLQ | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0032508 | Census, Compendium | Yes | 364 | 0.141 | 949 | 135 | 0.142 | 0 |
| POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | GO:0032508 | Census, Compendium | Yes | 113 | 0.178 | 31 | 6 | 0.194 | 9 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0032508 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD54B | RAD54B | Q9Y620 | DNA repair and recombination protein RAD54B | chr8 | GO:0032508 | Not Cancer Driver | No | 112 | 0.123 | 120 | 16 | 0.133 | 0 |
| RAD54L2 | RAD54L2 | Q9Y4B4 | Helicase ARIP4 | chr3 | GO:0032508 | Not Cancer Driver | No | 194 | 0.132 | 753 | 97 | 0.129 | 0 |
| RAD54L_ENST00000442598 | RAD54L | Q92698 | DNA repair and recombination protein RAD54-like | chr1 | GO:0032508 | Not Cancer Driver | No | 79 | 0.106 | 124 | 13 | 0.105 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | GO:0032508 | Census, Compendium | Yes | 138 | 0.114 | 608 | 71 | 0.117 | 1 |
| RECQL5 | RECQL5 | O94762 | ATP-dependent DNA helicase Q5 | chr17 | GO:0032508 | Not Cancer Driver | No | 132 | 0.133 | 495 | 71 | 0.143 | 0 |
| RECQL_ENST00000421138 | RECQL | P46063 | ATP-dependent DNA helicase Q1 | chr12 | GO:0032508 | Not Cancer Driver | No | 67 | 0.103 | 91 | 5 | 0.055 | 0 |
| RFC2 | RFC2 | P35250 | Replication factor C subunit 2 | chr7 | GO:0032508 | Not Cancer Driver | No | 45 | 0.127 | 39 | 6 | 0.154 | 0 |
| RFC3 | RFC3 | P40938 | Replication factor C subunit 3 | chr13 | GO:0032508 | Not Cancer Driver | No | 31 | 0.087 | 13 | 1 | 0.077 | 0 |
| RFC4_ENST00000296273 | RFC4 | P35249 | Replication factor C subunit 4 | chr3 | GO:0032508 | Not Cancer Driver | No | 58 | 0.16 | 50 | 8 | 0.16 | 0 |
| RFC5 | RFC5 | P40937 | Replication factor C subunit 5 | chr12 | GO:0032508 | Not Cancer Driver | No | 38 | 0.112 | 20 | 1 | 0.05 | 0 |
| RTEL1_ENST00000370018 | RTEL1 | Q9NZ71 | Regulator of telomere elongation helicase 1 | chr20 | GO:0032508 | Not Cancer Driver | No | 144 | 0.118 | 474 | 64 | 0.135 | 14 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | GO:0032508 | Not Cancer Driver | No | 54 | 0.118 | 67 | 7 | 0.104 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0032508 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
| SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0032508 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
| SMARCAD1_ENST00000354268 | SMARCAD1 | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 | chr4 | GO:0032508 | Not Cancer Driver | No | 129 | 0.126 | 388 | 50 | 0.129 | 0 |
| SUPV3L1 | SUPV3L1 | Q8IYB8 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | chr10 | GO:0032508 | Not Cancer Driver | No | 72 | 0.092 | 140 | 12 | 0.086 | 0 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0032508 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0032508 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0032508 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |
| WRNIP1 | WRNIP1 | Q96S55 | ATPase WRNIP1 | chr6 | GO:0032508 | Not Cancer Driver | No | 50 | 0.075 | 292 | 7 | 0.024 | 0 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0032508 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0032508 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |