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Total number of protein in "GO:0032496" GO term:  128

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0032496 Not Cancer Driver No 255 0.161 138 23 0.167 97
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0032496 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0032496 Not Cancer Driver No 51 0.157 31 6 0.194 8
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0032496 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADH5 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 GO:0032496 Not Cancer Driver No 36 0.096 2 1 0.5 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0032496 Not Cancer Driver No 20 0.108 113 13 0.115 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0032496 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKIRIN2 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0032496 Not Cancer Driver No 21 0.103 119 11 0.092 0
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0032496 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0032496 Not Cancer Driver No 80 0.153 184 39 0.212 113
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0032496 Not Cancer Driver No 1022 0.224 315 72 0.229 3
ATP4B ATP4B P51164 Potassium-transporting ATPase subunit beta chr13 GO:0032496 Not Cancer Driver No 35 0.12 2 0 0.0 0
BDKRB1_ENST00000611804 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0032496 Not Cancer Driver No 68 0.193 3 0 0.0 0
C2 C2 P06681 Complement C2 chr6 GO:0032496 Not Cancer Driver No 120 0.16 120 17 0.142 3
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0032496 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0032496 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0032496 Census Yes 49 0.118 71 7 0.099 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0032496 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0032496 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0032496 Not Cancer Driver No 132 0.226 165 34 0.206 1
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0032496 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0032496 Not Cancer Driver No 31 0.147 16 3 0.188 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0032496 Not Cancer Driver No 36 0.086 71 2 0.028 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0032496 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 GO:0032496 Not Cancer Driver No 57 0.158 21 4 0.19 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0032496 Not Cancer Driver No 368 0.245 73 22 0.301 140
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0032496 Not Cancer Driver No 204 0.227 541 120 0.222 0
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0032496 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0032496 Not Cancer Driver No 71 0.14 79 13 0.165 18
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0032496 Not Cancer Driver No 73 0.267 44 4 0.091 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0032496 Not Cancer Driver No 81 0.168 135 24 0.178 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0032496 Not Cancer Driver No 37 0.175 97 20 0.206 3
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0032496 Not Cancer Driver No 39 0.146 18 3 0.167 89
EPO EPO P01588 Erythropoietin chr7 GO:0032496 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:0032496 Not Cancer Driver No 167 0.118 967 118 0.122 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0032496 Not Cancer Driver No 73 0.172 19 2 0.105 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0032496 Not Cancer Driver No 65 0.231 94 18 0.191 1
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0032496 Not Cancer Driver No 114 0.139 145 21 0.145 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0032496 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0032496 Census, Compendium Yes 238 0.29 228 44 0.193 72
FMO1 FMO1 Q01740 Dimethylaniline monooxygenase [N-oxide-forming] 1 chr1 GO:0032496 Not Cancer Driver No 133 0.25 3 0 0.0 0
FOS FOS P01100 Protein c-Fos chr14 GO:0032496 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0032496 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0032496 Not Cancer Driver No 38 0.088 186 16 0.086 10
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0032496 Not Cancer Driver No 20 0.08 99 5 0.051 38
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0032496 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0032496 Not Cancer Driver No 42 0.161 12 4 0.333 4
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0032496 Not Cancer Driver No 46 0.094 145 14 0.097 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0032496 Not Cancer Driver No 38 0.182 207 38 0.184 0
HNRNPA0 HNRNPA0 Q13151 Heterogeneous nuclear ribonucleoprotein A0 chr5 GO:0032496 Not Cancer Driver No 25 0.082 172 14 0.081 0
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0032496 Not Cancer Driver No 32 0.12 4 1 0.25 2
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0032496 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 GO:0032496 Compendium Yes 55 0.099 50 6 0.12 0
IL10RA IL10RA Q13651 Interleukin-10 receptor subunit alpha chr11 GO:0032496 Not Cancer Driver No 77 0.133 220 26 0.118 7
IL12RB2 IL12RB2 Q99665 Interleukin-12 receptor subunit beta-2 chr1 GO:0032496 Not Cancer Driver No 129 0.15 195 31 0.159 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0032496 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0032496 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0032496 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0032496 Not Cancer Driver No 70 0.111 117 19 0.162 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0032496 Compendium Yes 71 0.1 337 39 0.116 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0032496 Not Cancer Driver No 103 0.173 79 14 0.177 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0032496 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUND JUND P17535 Transcription factor JunD chr19 GO:0032496 Not Cancer Driver No 21 0.061 313 19 0.061 0
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0032496 Not Cancer Driver No 99 0.233 68 22 0.324 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0032496 Not Cancer Driver No 84 0.175 6 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0032496 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIAS LIAS O43766 Lipoyl synthase, mitochondrial chr4 GO:0032496 Not Cancer Driver No 46 0.124 82 10 0.122 1
LOXL1 LOXL1 Q08397 Lysyl oxidase homolog 1 chr15 GO:0032496 Not Cancer Driver No 49 0.085 337 14 0.042 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0032496 Not Cancer Driver No 37 0.18 20 5 0.25 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0032496 Not Cancer Driver No 37 0.231 0 0 0.0 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0032496 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0032496 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK3 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 GO:0032496 Not Cancer Driver No 35 0.092 117 12 0.103 1
MPO MPO P05164 Myeloperoxidase chr17 GO:0032496 Not Cancer Driver No 149 0.2 52 12 0.231 3
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0032496 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0032496 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0032496 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0032496 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0032496 Census, Compendium Yes 363 0.142 686 87 0.127 3
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0032496 Not Cancer Driver No 62 0.104 252 24 0.095 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0032496 Not Cancer Driver No 107 0.268 58 27 0.466 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0032496 Not Cancer Driver No 55 0.096 430 39 0.091 4
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0032496 Not Cancer Driver No 51 0.086 14 2 0.143 0
PALM3 PALM3 A6NDB9 Paralemmin-3 chr19 GO:0032496 Not Cancer Driver No 26 0.039 635 23 0.036 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0032496 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0032496 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0032496 Not Cancer Driver No 139 0.185 336 61 0.182 2
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0032496 Not Cancer Driver No 47 0.112 167 17 0.102 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0032496 Not Cancer Driver No 109 0.408 142 62 0.437 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0032496 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0032496 Not Cancer Driver No 23 0.09 23 3 0.13 0
PTGER1 PTGER1 P34995 Prostaglandin E2 receptor EP1 subtype chr19 GO:0032496 Not Cancer Driver No 7 0.017 26 1 0.038 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0032496 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0032496 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0032496 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGIR PTGIR P43119 Prostacyclin receptor chr19 GO:0032496 Not Cancer Driver No 40 0.104 47 4 0.085 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0032496 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0032496 Not Cancer Driver No 141 0.175 364 62 0.17 4
REN REN P00797 Renin chr1 GO:0032496 Not Cancer Driver No 60 0.148 10 0 0.0 3
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0032496 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0032496 Not Cancer Driver No 45 0.086 226 26 0.115 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0032496 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0032496 Census Yes 39 0.386 28 14 0.5 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0032496 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0032496 Not Cancer Driver No 18 0.158 76 7 0.092 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0032496 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0032496 Not Cancer Driver No 12 0.132 14 2 0.143 0
SELE SELE P16581 E-selectin chr1 GO:0032496 Not Cancer Driver No 137 0.225 12 0 0.0 0
SELP SELP P16109 P-selectin chr1 GO:0032496 Not Cancer Driver No 226 0.272 14 2 0.143 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0032496 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLPI SLPI P03973 Antileukoproteinase chr20 GO:0032496 Not Cancer Driver No 20 0.152 0 0 0.0 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0032496 Not Cancer Driver No 38 0.077 248 7 0.028 7
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0032496 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0032496 Not Cancer Driver No 32 0.144 25 5 0.2 0
SRR SRR Q9GZT4 Serine racemase chr17 GO:0032496 Not Cancer Driver No 40 0.118 32 6 0.188 0
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 GO:0032496 Not Cancer Driver No 87 0.126 573 73 0.127 2
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0032496 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBD THBD P07204 Thrombomodulin chr20 GO:0032496 Not Cancer Driver No 39 0.068 51 3 0.059 9
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0032496 Not Cancer Driver No 30 0.134 8 2 0.25 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0032496 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0032496 Not Cancer Driver No 292 0.348 0 0 0.0 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0032496 Not Cancer Driver No 70 0.114 285 33 0.116 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0032496 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0032496 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0032496 Not Cancer Driver No 86 0.176 47 15 0.319 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0032496 Not Cancer Driver No 100 0.188 11 2 0.182 55
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0032496 Not Cancer Driver No 188 0.254 110 28 0.255 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 GO:0032496 Not Cancer Driver No 28 0.089 35 3 0.086 0