Total number of protein in "GO:0032446" GO term: 143
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0032446 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| ANKRD39 | ANKRD39 | Q53RE8 | Ankyrin repeat domain-containing protein 39 | chr2 | GO:0032446 | Not Cancer Driver | No | 19 | 0.104 | 38 | 2 | 0.053 | 0 |
| AREL1 | AREL1 | O15033 | Apoptosis-resistant E3 ubiquitin protein ligase 1 | chr14 | GO:0032446 | Not Cancer Driver | No | 104 | 0.126 | 92 | 10 | 0.109 | 0 |
| ASB4 | ASB4 | Q9Y574 | Ankyrin repeat and SOCS box protein 4 | chr7 | GO:0032446 | Not Cancer Driver | No | 82 | 0.192 | 19 | 1 | 0.053 | 0 |
| ATG10 | ATG10 | Q9H0Y0 | Ubiquitin-like-conjugating enzyme ATG10 | chr5 | GO:0032446 | Not Cancer Driver | No | 22 | 0.1 | 9 | 1 | 0.111 | 0 |
| ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0032446 | Compendium | Yes | 77 | 0.11 | 53 | 8 | 0.151 | 6 |
| ATXN7L3_ENST00000389384 | ATXN7L3 | Q14CW9 | Ataxin-7-like protein 3 | chr17 | GO:0032446 | Not Cancer Driver | No | 41 | 0.118 | 241 | 27 | 0.112 | 0 |
| BARD1 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | GO:0032446 | Census | Yes | 96 | 0.124 | 384 | 49 | 0.128 | 0 |
| BCOR | BCOR | Q6W2J9 | BCL-6 corepressor | chrX | GO:0032446 | Census, Compendium | Yes | 291 | 0.166 | 1285 | 226 | 0.176 | 1 |
| BFAR | BFAR | Q9NZS9 | Bifunctional apoptosis regulator | chr16 | GO:0032446 | Not Cancer Driver | No | 56 | 0.124 | 30 | 1 | 0.033 | 0 |
| BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | GO:0032446 | Not Cancer Driver | No | 50 | 0.153 | 150 | 30 | 0.2 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0032446 | Census, Compendium | Yes | 224 | 0.12 | 1458 | 174 | 0.119 | 35 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0032446 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| CDC73 | CDC73 | Q6P1J9 | Parafibromin | chr1 | GO:0032446 | Census, Compendium | Yes | 110 | 0.207 | 210 | 39 | 0.186 | 2 |
| CDK5RAP3_ENST00000338399 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0032446 | Not Cancer Driver | No | 50 | 0.099 | 99 | 20 | 0.202 | 0 |
| CNOT4_ENST00000315544 | CNOT4 | O95628 | CCR4-NOT transcription complex subunit 4 | chr7 | GO:0032446 | Not Cancer Driver | No | 73 | 0.127 | 359 | 35 | 0.097 | 0 |
| CTR9 | CTR9 | Q6PD62 | RNA polymerase-associated protein CTR9 homolog | chr11 | GO:0032446 | Not Cancer Driver | No | 164 | 0.14 | 385 | 48 | 0.125 | 0 |
| CTU1 | CTU1 | Q7Z7A3 | Cytoplasmic tRNA 2-thiolation protein 1 | chr19 | GO:0032446 | Not Cancer Driver | No | 12 | 0.034 | 60 | 1 | 0.017 | 0 |
| CTU2_ENST00000453996 | CTU2 | Q2VPK5 | Cytoplasmic tRNA 2-thiolation protein 2 | chr16 | GO:0032446 | Not Cancer Driver | No | 46 | 0.089 | 137 | 11 | 0.08 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0032446 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | GO:0032446 | Not Cancer Driver | No | 138 | 0.151 | 207 | 38 | 0.184 | 2 |
| DCUN1D1 | DCUN1D1 | Q96GG9 | DCN1-like protein 1 | chr3 | GO:0032446 | Not Cancer Driver | No | 34 | 0.131 | 13 | 0 | 0.0 | 0 |
| DCUN1D2 | DCUN1D2 | Q6PH85 | DCN1-like protein 2 | chr13 | GO:0032446 | Not Cancer Driver | No | 36 | 0.139 | 29 | 7 | 0.241 | 0 |
| DCUN1D3 | DCUN1D3 | Q8IWE4 | DCN1-like protein 3 | chr16 | GO:0032446 | Not Cancer Driver | No | 36 | 0.118 | 118 | 9 | 0.076 | 0 |
| DCUN1D4_ENST00000334635 | DCUN1D4 | Q92564 | DCN1-like protein 4 | chr4 | GO:0032446 | Not Cancer Driver | No | 51 | 0.175 | 57 | 12 | 0.211 | 0 |
| DCUN1D5 | DCUN1D5 | Q9BTE7 | DCN1-like protein 5 | chr11 | GO:0032446 | Not Cancer Driver | No | 18 | 0.076 | 7 | 0 | 0.0 | 0 |
| DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0032446 | Not Cancer Driver | No | 126 | 0.111 | 50 | 8 | 0.16 | 4 |
| DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0032446 | Census, Compendium | Yes | 45 | 0.105 | 70 | 5 | 0.071 | 2 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | GO:0032446 | Not Cancer Driver | No | 34 | 0.108 | 181 | 23 | 0.127 | 0 |
| DTX3L | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:0032446 | Not Cancer Driver | No | 86 | 0.116 | 260 | 24 | 0.092 | 0 |
| ERCC8 | ERCC8 | Q13216 | DNA excision repair protein ERCC-8 | chr5 | GO:0032446 | Not Cancer Driver | No | 25 | 0.063 | 53 | 8 | 0.151 | 7 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0032446 | Not Cancer Driver | No | 274 | 0.105 | 991 | 108 | 0.109 | 0 |
| HERC5 | HERC5 | Q9UII4 | E3 ISG15--protein ligase HERC5 | chr4 | GO:0032446 | Not Cancer Driver | No | 124 | 0.121 | 118 | 12 | 0.102 | 0 |
| ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | GO:0032446 | Not Cancer Driver | No | 12 | 0.073 | 24 | 2 | 0.083 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0032446 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| KDM2B | KDM2B | Q8NHM5 | Lysine-specific demethylase 2B | chr12 | GO:0032446 | Not Cancer Driver | No | 187 | 0.14 | 617 | 90 | 0.146 | 0 |
| KLHL20 | KLHL20 | Q9Y2M5 | Kelch-like protein 20 | chr1 | GO:0032446 | Not Cancer Driver | No | 83 | 0.136 | 143 | 17 | 0.119 | 0 |
| KLHL24_ENST00000242810 | KLHL24 | Q6TFL4 | Kelch-like protein 24 | chr3 | GO:0032446 | Not Cancer Driver | No | 102 | 0.17 | 17 | 6 | 0.353 | 0 |
| LEO1 | LEO1 | Q8WVC0 | RNA polymerase-associated protein LEO1 | chr15 | GO:0032446 | Not Cancer Driver | No | 74 | 0.111 | 611 | 69 | 0.113 | 0 |
| LRSAM1_ENST00000373322 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | GO:0032446 | Not Cancer Driver | No | 86 | 0.119 | 240 | 30 | 0.125 | 1 |
| LTN1_ENST00000361371 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | GO:0032446 | Not Cancer Driver | No | 192 | 0.109 | 124 | 23 | 0.185 | 0 |
| MARCH5 | MARCHF5 | Q9NX47 | E3 ubiquitin-protein ligase MARCHF5 | chr10 | GO:0032446 | Not Cancer Driver | No | 27 | 0.097 | 0 | 0 | 0.0 | 0 |
| MARCH7 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:0032446 | Not Cancer Driver | No | 85 | 0.121 | 550 | 68 | 0.124 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0032446 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MOCS3 | MOCS3 | O95396 | Adenylyltransferase and sulfurtransferase MOCS3 | chr20 | GO:0032446 | Not Cancer Driver | No | 61 | 0.133 | 15 | 5 | 0.333 | 0 |
| NAE1_ENST00000290810 | NAE1 | Q13564 | NEDD8-activating enzyme E1 regulatory subunit | chr16 | GO:0032446 | Not Cancer Driver | No | 39 | 0.073 | 69 | 3 | 0.043 | 0 |
| NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | GO:0032446 | Not Cancer Driver | No | 10 | 0.123 | 36 | 5 | 0.139 | 0 |
| NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | GO:0032446 | Not Cancer Driver | No | 121 | 0.108 | 491 | 46 | 0.094 | 0 |
| PAF1 | PAF1 | Q8N7H5 | RNA polymerase II-associated factor 1 homolog | chr19 | GO:0032446 | Not Cancer Driver | No | 77 | 0.145 | 378 | 56 | 0.148 | 0 |
| PCGF1 | PCGF1 | Q9BSM1 | Polycomb group RING finger protein 1 | chr2 | GO:0032446 | Not Cancer Driver | No | 28 | 0.108 | 8 | 0 | 0.0 | 0 |
| PCGF3 | PCGF3 | Q3KNV8 | Polycomb group RING finger protein 3 | chr4 | GO:0032446 | Not Cancer Driver | No | 38 | 0.157 | 47 | 11 | 0.234 | 0 |
| PCGF5 | PCGF5 | Q86SE9 | Polycomb group RING finger protein 5 | chr10 | GO:0032446 | Not Cancer Driver | No | 31 | 0.121 | 52 | 5 | 0.096 | 0 |
| PCGF6 | PCGF6 | Q9BYE7 | Polycomb group RING finger protein 6 | chr10 | GO:0032446 | Not Cancer Driver | No | 29 | 0.083 | 142 | 11 | 0.077 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0032446 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0032446 | Not Cancer Driver | No | 59 | 0.119 | 328 | 43 | 0.131 | 0 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0032446 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:0032446 | Not Cancer Driver | No | 52 | 0.102 | 140 | 14 | 0.1 | 2 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0032446 | Not Cancer Driver | No | 10 | 0.093 | 18 | 1 | 0.056 | 0 |
| RING1 | RING1 | Q06587 | E3 ubiquitin-protein ligase RING1 | chr6 | GO:0032446 | Not Cancer Driver | No | 60 | 0.148 | 302 | 44 | 0.146 | 0 |
| RNF10_ENST00000325954 | RNF10 | Q8N5U6 | RING finger protein 10 | chr12 | GO:0032446 | Not Cancer Driver | No | 108 | 0.133 | 455 | 63 | 0.138 | 0 |
| RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | GO:0032446 | Not Cancer Driver | No | 17 | 0.11 | 76 | 7 | 0.092 | 0 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0032446 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| RNF115 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | GO:0032446 | Not Cancer Driver | No | 30 | 0.099 | 136 | 14 | 0.103 | 0 |
| RNF122 | RNF122 | Q9H9V4 | RING finger protein 122 | chr8 | GO:0032446 | Not Cancer Driver | No | 24 | 0.155 | 0 | 0 | 0.0 | 0 |
| RNF133 | RNF133 | Q8WVZ7 | E3 ubiquitin-protein ligase RNF133 | chr7 | GO:0032446 | Not Cancer Driver | No | 76 | 0.202 | 60 | 5 | 0.083 | 0 |
| RNF13_ENST00000392894 | RNF13 | O43567 | E3 ubiquitin-protein ligase RNF13 | chr3 | GO:0032446 | Not Cancer Driver | No | 45 | 0.118 | 107 | 17 | 0.159 | 2 |
| RNF141 | RNF141 | Q8WVD5 | RING finger protein 141 | chr11 | GO:0032446 | Not Cancer Driver | No | 28 | 0.122 | 48 | 4 | 0.083 | 0 |
| RNF146 | RNF146 | Q9NTX7 | E3 ubiquitin-protein ligase RNF146 | chr6 | GO:0032446 | Not Cancer Driver | No | 37 | 0.103 | 206 | 24 | 0.117 | 0 |
| RNF157 | RNF157 | Q96PX1 | E3 ubiquitin ligase RNF157 | chr17 | GO:0032446 | Not Cancer Driver | No | 76 | 0.112 | 375 | 39 | 0.104 | 0 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0032446 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF181 | RNF181 | Q9P0P0 | E3 ubiquitin-protein ligase RNF181 | chr2 | GO:0032446 | Not Cancer Driver | No | 15 | 0.098 | 63 | 8 | 0.127 | 0 |
| RNF183_ENST00000297894 | RNF183 | Q96D59 | E3 ubiquitin-protein ligase RNF183 | chr9 | GO:0032446 | Not Cancer Driver | No | 22 | 0.115 | 29 | 1 | 0.034 | 0 |
| RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0032446 | Not Cancer Driver | No | 25 | 0.13 | 82 | 15 | 0.183 | 0 |
| RNF186 | RNF186 | Q9NXI6 | E3 ubiquitin-protein ligase RNF186 | chr1 | GO:0032446 | Not Cancer Driver | No | 27 | 0.119 | 11 | 3 | 0.273 | 0 |
| RNF187_ENST00000639044 | RNF187 | Q5TA31 | E3 ubiquitin-protein ligase RNF187 | chr1 | GO:0032446 | Not Cancer Driver | No | 2 | 0.009 | 104 | 1 | 0.01 | 0 |
| RNF19B | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0032446 | Not Cancer Driver | No | 58 | 0.079 | 344 | 24 | 0.07 | 0 |
| RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | GO:0032446 | Not Cancer Driver | No | 40 | 0.119 | 203 | 22 | 0.108 | 0 |
| RNF20 | RNF20 | Q5VTR2 | E3 ubiquitin-protein ligase BRE1A | chr9 | GO:0032446 | Not Cancer Driver | No | 126 | 0.129 | 561 | 64 | 0.114 | 0 |
| RNF208 | RNF208 | Q9H0X6 | RING finger protein 208 | chr9 | GO:0032446 | Not Cancer Driver | No | 20 | 0.077 | 113 | 9 | 0.08 | 0 |
| RNF213 | RNF213 | Q63HN8 | E3 ubiquitin-protein ligase RNF213 | chr17 | GO:0032446 | Census, Compendium | Yes | 560 | 0.108 | 623 | 75 | 0.12 | 3 |
| RNF219 | OBI1 | Q5W0B1 | ORC ubiquitin ligase 1 | chr13 | GO:0032446 | Not Cancer Driver | No | 96 | 0.132 | 486 | 67 | 0.138 | 0 |
| RNF220_ENST00000361799 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | GO:0032446 | Not Cancer Driver | No | 104 | 0.184 | 401 | 75 | 0.187 | 0 |
| RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | GO:0032446 | Not Cancer Driver | No | 142 | 0.132 | 319 | 45 | 0.141 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | GO:0032446 | Not Cancer Driver | No | 14 | 0.074 | 117 | 7 | 0.06 | 0 |
| RNF40 | RNF40 | O75150 | E3 ubiquitin-protein ligase BRE1B | chr16 | GO:0032446 | Not Cancer Driver | No | 132 | 0.132 | 645 | 80 | 0.124 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0032446 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| RNF6 | RNF6 | Q9Y252 | E3 ubiquitin-protein ligase RNF6 | chr13 | GO:0032446 | Compendium | Yes | 91 | 0.133 | 601 | 87 | 0.145 | 0 |
| RNF7 | RNF7 | Q9UBF6 | RING-box protein 2 | chr3 | GO:0032446 | Not Cancer Driver | No | 17 | 0.15 | 0 | 0 | 0.0 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0032446 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| RNFT1 | RNFT1 | Q5M7Z0 | E3 ubiquitin-protein ligase RNFT1 | chr17 | GO:0032446 | Not Cancer Driver | No | 37 | 0.085 | 117 | 18 | 0.154 | 0 |
| RYBP | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | GO:0032446 | Not Cancer Driver | No | 37 | 0.162 | 214 | 37 | 0.173 | 0 |
| SAE1 | SAE1 | Q9UBE0 | SUMO-activating enzyme subunit 1 | chr19 | GO:0032446 | Not Cancer Driver | No | 39 | 0.113 | 90 | 6 | 0.067 | 0 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0032446 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0032446 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SH3RF3 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0032446 | Not Cancer Driver | No | 98 | 0.111 | 564 | 53 | 0.094 | 0 |
| SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | GO:0032446 | Not Cancer Driver | No | 34 | 0.088 | 237 | 16 | 0.068 | 0 |
| SKP1_ENST00000517625 | SKP1 | P63208 | S-phase kinase-associated protein 1 | chr5 | GO:0032446 | Not Cancer Driver | No | 19 | 0.117 | 95 | 17 | 0.179 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0032446 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0032446 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0032446 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRIM13_ENST00000378182 | TRIM13 | O60858 | E3 ubiquitin-protein ligase TRIM13 | chr13 | GO:0032446 | Not Cancer Driver | No | 53 | 0.13 | 1 | 0 | 0.0 | 0 |
| TRIM17_ENST00000366698 | TRIM17 | Q9Y577 | E3 ubiquitin-protein ligase TRIM17 | chr1 | GO:0032446 | Not Cancer Driver | No | 64 | 0.134 | 127 | 19 | 0.15 | 0 |
| TRIM21 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0032446 | Not Cancer Driver | No | 85 | 0.179 | 49 | 7 | 0.143 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0032446 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | GO:0032446 | Not Cancer Driver | No | 119 | 0.123 | 492 | 60 | 0.122 | 3 |
| TRIM40_ENST00000376724 | TRIM40 | Q6P9F5 | E3 ubiquitin ligase TRIM40 | chr6 | GO:0032446 | Not Cancer Driver | No | 44 | 0.171 | 84 | 12 | 0.143 | 0 |
| TRIM52 | TRIM52 | Q96A61 | E3 ubiquitin-protein ligase TRIM52 | chr5 | GO:0032446 | Not Cancer Driver | No | 23 | 0.077 | 147 | 13 | 0.088 | 0 |
| TRIM58 | TRIM58 | Q8NG06 | E3 ubiquitin-protein ligase TRIM58 | chr1 | GO:0032446 | Not Cancer Driver | No | 194 | 0.399 | 84 | 41 | 0.488 | 0 |
| TRIM62 | TRIM62 | Q9BVG3 | E3 ubiquitin-protein ligase TRIM62 | chr1 | GO:0032446 | Not Cancer Driver | No | 58 | 0.122 | 80 | 14 | 0.175 | 0 |
| TRIM68 | TRIM68 | Q6AZZ1 | E3 ubiquitin-protein ligase TRIM68 | chr11 | GO:0032446 | Not Cancer Driver | No | 74 | 0.153 | 37 | 7 | 0.189 | 0 |
| TRIM71 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0032446 | Not Cancer Driver | No | 124 | 0.143 | 163 | 21 | 0.129 | 2 |
| UBA1 | UBA1 | P22314 | Ubiquitin-like modifier-activating enzyme 1 | chrX | GO:0032446 | Not Cancer Driver | No | 117 | 0.111 | 165 | 22 | 0.133 | 6 |
| UBA2 | UBA2 | Q9UBT2 | SUMO-activating enzyme subunit 2 | chr19 | GO:0032446 | Not Cancer Driver | No | 84 | 0.131 | 219 | 33 | 0.151 | 0 |
| UBA3 | UBA3 | Q8TBC4 | NEDD8-activating enzyme E1 catalytic subunit | chr3 | GO:0032446 | Not Cancer Driver | No | 48 | 0.104 | 44 | 4 | 0.091 | 0 |
| UBA5 | UBA5 | Q9GZZ9 | Ubiquitin-like modifier-activating enzyme 5 | chr3 | GO:0032446 | Not Cancer Driver | No | 41 | 0.101 | 126 | 8 | 0.063 | 7 |
| UBA6 | UBA6 | A0AVT1 | Ubiquitin-like modifier-activating enzyme 6 | chr4 | GO:0032446 | Not Cancer Driver | No | 133 | 0.126 | 90 | 10 | 0.111 | 0 |
| UBA7 | UBA7 | P41226 | Ubiquitin-like modifier-activating enzyme 7 | chr3 | GO:0032446 | Not Cancer Driver | No | 92 | 0.091 | 166 | 15 | 0.09 | 0 |
| UBD | UBD | O15205 | Ubiquitin D | chr6 | GO:0032446 | Not Cancer Driver | No | 31 | 0.188 | 8 | 1 | 0.125 | 0 |
| UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | GO:0032446 | Compendium | Yes | 35 | 0.23 | 67 | 13 | 0.194 | 2 |
| UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0032446 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
| UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | GO:0032446 | Compendium | Yes | 19 | 0.129 | 13 | 1 | 0.077 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0032446 | Not Cancer Driver | No | 21 | 0.143 | 13 | 4 | 0.308 | 0 |
| UBE2D4 | UBE2D4 | Q9Y2X8 | Ubiquitin-conjugating enzyme E2 D4 | chr7 | GO:0032446 | Not Cancer Driver | No | 13 | 0.088 | 21 | 1 | 0.048 | 0 |
| UBE2E1 | UBE2E1 | P51965 | Ubiquitin-conjugating enzyme E2 E1 | chr3 | GO:0032446 | Not Cancer Driver | No | 21 | 0.109 | 78 | 10 | 0.128 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | GO:0032446 | Not Cancer Driver | No | 28 | 0.139 | 90 | 15 | 0.167 | 0 |
| UBE2F_ENST00000272930 | UBE2F | Q969M7 | NEDD8-conjugating enzyme UBE2F | chr2 | GO:0032446 | Not Cancer Driver | No | 21 | 0.114 | 19 | 5 | 0.263 | 0 |
| UBE2L6 | UBE2L6 | O14933 | Ubiquitin/ISG15-conjugating enzyme E2 L6 | chr11 | GO:0032446 | Not Cancer Driver | No | 19 | 0.124 | 7 | 1 | 0.143 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | GO:0032446 | Not Cancer Driver | No | 30 | 0.164 | 32 | 6 | 0.188 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | GO:0032446 | Not Cancer Driver | No | 25 | 0.113 | 102 | 12 | 0.118 | 0 |
| UBE2T | UBE2T | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | chr1 | GO:0032446 | Not Cancer Driver | No | 12 | 0.061 | 97 | 9 | 0.093 | 1 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0032446 | Not Cancer Driver | No | 141 | 0.161 | 136 | 22 | 0.162 | 0 |
| UBE3C | UBE3C | Q15386 | Ubiquitin-protein ligase E3C | chr7 | GO:0032446 | Not Cancer Driver | No | 143 | 0.132 | 65 | 12 | 0.185 | 0 |
| UBE3D | UBE3D | Q7Z6J8 | E3 ubiquitin-protein ligase E3D | chr6 | GO:0032446 | Not Cancer Driver | No | 51 | 0.131 | 9 | 3 | 0.333 | 0 |
| UFC1 | UFC1 | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme 1 | chr1 | GO:0032446 | Not Cancer Driver | No | 24 | 0.144 | 10 | 0 | 0.0 | 2 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0032446 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
| UFM1_ENST00000239878 | UFM1 | P61960 | Ubiquitin-fold modifier 1 | chr13 | GO:0032446 | Not Cancer Driver | No | 10 | 0.118 | 0 | 0 | 0.0 | 1 |
| UHRF1_ENST00000616255 | UHRF1 | Q96T88 | E3 ubiquitin-protein ligase UHRF1 | chr19 | GO:0032446 | Not Cancer Driver | No | 97 | 0.122 | 353 | 49 | 0.139 | 0 |
| UHRF2 | UHRF2 | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | chr9 | GO:0032446 | Not Cancer Driver | No | 88 | 0.11 | 253 | 22 | 0.087 | 0 |
| URM1_ENST00000372853 | URM1 | Q9BTM9 | Ubiquitin-related modifier 1 | chr9 | GO:0032446 | Not Cancer Driver | No | 7 | 0.069 | 0 | 0 | 0.0 | 0 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0032446 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| WSB1 | WSB1 | Q9Y6I7 | WD repeat and SOCS box-containing protein 1 | chr17 | GO:0032446 | Not Cancer Driver | No | 48 | 0.114 | 25 | 3 | 0.12 | 0 |
| WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0032446 | Not Cancer Driver | No | 112 | 0.129 | 422 | 57 | 0.135 | 0 |
| ZBED1 | ZBED1 | O96006 | E3 SUMO-protein ligase ZBED1 | chrX | GO:0032446 | Not Cancer Driver | No | 137 | 0.197 | 97 | 12 | 0.124 | 0 |